• 순환기질환의공학회:학술대회논문집
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• 2004.11a
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• pp.9-10
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• 2004

• Journal of Sasang Constitutional Medicine
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• v.1 no.1
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• pp.87-112
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• 1989

In order to investigate experimentally the effects of Sung-yangikgibujat'ang (SIT) and Kwangyebujalijungt'ang (KBT) on Yang-insufficient syndrome (陽虛證) induced by Hydrocortisone acetate (H.A.) in experimental animals (Mice and Rat), the author experimented various activities. Delayed type hypersensitivity (DTH), Rosette forming cells (RFC), hemagglutinin (HA) titers, Hemolysin (HL) titers, Body weight, Whole blood viscosity, Plasma Viscosity, Hematocrit, RBC, Albumin, Total protein, Triglyceride, cholesterol and Glucose were measured. The results summerized as follows; 1. In DTH and RFC all the experimental groups were increased significantly in comparison to the H.A.-treated group. 2. In HA titers SIT_treated group were increased significantly and KBT-treated group showed increasing tendancy, but showed no significance. 3. In HL titers all the experimental groups showed increasing tendancy, but showed no significance. 4. In body weight all the experimental groups showed increasing tendancy, but showed no significance. 5. In whole blood viscosity all the experimental groups were decreased significantly in comparison to the H.A.-treated group. 5. In whole blood viscosity all the experimental groups were decreased significantly in comparison to the H.A.-treated group. 6. In plasma viscosity KBT-treated group were decreased significantly and SIT-treated group showed decreasing tendancy, but showed no significance. 7. In Hematocrit SIT-treated group were decreased significantly and KBT-treated group showed decreasing tendancy, but showed no significance. 8. In RBC, albumin and cholesterol all the experimental groups were decreased significantly in comparison to the H.A.-treated group. 9. In total protein and triglyceride KBT-treated group were decreased significantly and SIT-treated group showed decreasing tendancy, but showed no significance. 10. In Glucose SIT-treated group were decreased significantly and KBT-treated group showed decreasing tendancy, but showed no significance. From above findings, it has been demonstrated that Sungyangikgibujat'ang and Kwangyebujalijungt'ang seem to produce the effectiveness on the recovery from depression of the cell-mediated immune response, blood circulation and energy metabolic rate, induced by Hydrocortisone acetate, and in the humoral immune response Sungyangikgibujat'ang have the effectiveness on the recovery, and in cellular component of blood Sungyangikgibujat'ang was more effective than Kwangyebujalijungt' ang, and in plasma of blood Kwangyebujalijungt'ang was more effective than Sungyangikgibujat'ang. Therefore it is suggested that Sungyangikgibujat'ang and Kwangyebujalijungt'ang have the effectiveness on the recovery from Yang-insufficient syndrome more or less.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2002.10b
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• pp.371-372
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• 2002

It is well known that red blood cells (RBCs) are suffered from chronic stresses in systemic circulation. The objective of this study is to clarify the effect of the aging of RBCs on rheological properties and hemolysis. Initially, RBCs age fractionation was performed by using a high-speed centrifugation (15[min] at 1500[G]), then young and aged RBCs were suspended in plasma to adjust the hematocrit level of 40[%]. After this pretreatment, the viscosity was measured by using a capillary type and a cone-plate type viscometers, respectively, and the hemolysis test was carried out by a seesaw type shaker. Results from these experiments showed that the viscosity of the aged RBCs measured by the capillary viscometer was increased by 10[%] as compared with that of the young RBCs. Under the condition of all shear zones, the viscosity of the aged RBCs was increased in case of using the cone-plate type viscometer. And the hemolytic level was increased twice as the aging. The data obtained in this study indicated that the ability of aggregation of RBCs was increased and the deformability of RBCs membrane got lower with the aging. Furthermore, it was exhibited that the fragility of RBCs ’ membrane was increased with the aging.

• Journal of Preventive Medicine and Public Health
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• v.30 no.3 s.58
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• pp.623-629
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• 1997

This is cross-sectional study to evaluate a potential relationship between air conduction hearing threshold and blood viscosity in normal adult males(n=1677). We measured hearing threshold in frequency level at 500, 1000, 2000, 4000Hz by pure-tone audiometry and RBC profiles containing red cell number, hemoglobin, hematocrit. Blood viscosity are replaced by hematocrit that are one major factor of influencing blood viscosity. PTAs(pure-tone averages) are measured by hearing threshold averages level at 500Hz, 1000Hz, 2000Hz. Grades of PTAs(pure-tone averages) are divided three groups that are less then 10.0dB group, between 10.0-19.9dB group and excess 20.0dB. The results shows significant association among hematocrit, red cell number and hearing loss(age adjust by ANACOVA).

• Journal of the Korean Applied Science and Technology
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• v.38 no.1
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• pp.271-279
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• 2021

The purpose of this study was to investigate the effects of maximum and endurance resistance exercises on total work, blood viscosity, and erythrocyte volume ratio. The study subjects were selected as 15 men in their twenties with 12 months or more of resistance exercise experience, and the bench press 1RM was measured before the experiment, and the experiment for each condition was cross-allocated at intervals of one week, and the maximum repetition was performed in 6 sets. As a result, the total amount of exercise showed that the muscular endurance strength was higher than that of the maximum muscular strength (p<.001), and the blood viscosity and erythrocyte volume ratio were higher after exercise than before (p<.01) regardless of the total exercise amount. In summary, it was found that blood viscosity was not affected by exercise intensity and amount of exercise, and increased with one-time resistance exercise. This is clinically significant in constructing a resistance exercise program, and it is considered to be a reference material in creating an exercise program for clinical patients related to vascular disease.

• 순환기질환의공학회:학술대회논문집
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• 2003.11a
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• pp.42-43
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• 2003

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.1682-1686
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• 2004

A slit-flow apparatus with laser diffraction method has been developed with significant advances in ektacytometry design, operation and data analysis. In the slit-flow ektacytometry (or laser-diffractometry), the deformation of red blood cells subjected to continuously decreasing shear stress in slit flow is measured. A laser beam traverses a diluted blood suspension flowing through a slit and is diffracted by RBCs in the volume. The diffraction patterns are captured by a CCD-video camera, linked to a frame grabber integrated with a computer, while the differential pressure variation is measured by a pressure transducer. Both measurements of laser-diffraction image and pressure with respect to time enable to determine deformation index and the shear stress. The range of shear stress of 0 ${\sim}$ 35 Pa and measuring time is less than 2 min. When deforming under decreasing shear stress, RBCs change gradually from the prolate ellipsoid towards a circular biconcave morphology. The Deformation Index (DI) as a measure of RBC deformability is determined from an isointensity curve in the diffraction pattern using an ellipse-fitting program. The advantages of this design are simplicity, i.e., ease of operation and no moving parts, low cost, short operating time, and the disposable kit which is contacted with blood sample.

• Preventive Nutrition and Food Science
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• v.3 no.4
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• pp.382-386
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• 1998

A soluble dietary fiber, $\beta$-glucan, contained in oat and barley has nutritional benefits such as hypocholesterolemic effects and influences blood glucose regulation. The contents of $\beta$-glucan in both cereals range from 3 to 7% with the exception of a certain barley genotype which contains up to 16% $\beta$-glucan. $\beta$-Glucan is distributed mainly in the cell walls of endosperm and the distal (bran) portion of kernel. Various procedures have been developed for increasing the extraction yield of $\beta$-glucan. Oat gum prepared with weak alkali extractionand alcohol proecipitation following protein removal usually contains 80% $\beta$-glucan.The most commonly used method for $\beta$-glucan quantitiation is an enzymatic procedure combining lichenase plus $\beta$-glucosidase followed by measuring the amount of glucos released by glucose oxidase-peroxidase treatment. The increase in foam-and emulsion-stabilizing capacity of $\beta$-glucan is due to the increase in viscosity of the aqueous phase. Therefore, $\beta$-glucan shows great potentials as a thickener and a stabilizer.

• Journal of Mechanical Science and Technology
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• v.18 no.12
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• pp.2258-2264
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• 2004

This article described the numerical investigation of shear-thinning blood flow characteristics when subjected to longitudinal and transverse vibrations and delineated the underlying mechanisms of the flow rate enhancements, respectively. In order to fully consider the mechanical vibrations of the capillary, a moving wall boundary condition was adopted. The present numerical results showed that the longitudinal vibration caused a significant increase of wall shear rates, which resulted in a decrease of viscosity and the subsequent increase of flow rates. However, the shear rate for the transverse vibration was slightly increased and the calculated flow rate was underestimated comparing with the previous experimental results.

• Journal of Applied Biological Chemistry
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• v.42 no.2
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• pp.81-84
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• 1999

Blood glue was prepared to reutilize porcine blood. Plasma proteins after lyophilization were treated by addition of wood flour, sodium hydroxide, sodium silicate, and hydrated lime to make blood glue with a suitable adhesivity. Characteristics of the prepared blood glue was monitored by measuring the viscosity with time, and the relationship between degree of hydrolysis of plasma proteins by addition of various amounts of sodium hydroxide and adhesivity was studied. To prevent the emission of formaldehyde during manufacturing of plywood by blood glue, the cross-linking reaction of plasma protein with formaldehyde was also examined. Fourier transform infrared, circular dichroism, and fluorescence spectroscopy study showed that blood plasma proteins react with formaldehyde, resulting in removal of formaldehyde by cross-linking reaction.