• 한국군사과학기술학회지
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• 제14권6호
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• pp.1159-1165
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• 2011

Telemetry techniques of rats have been used for assessing safety pharmacology of drugs and chemicals. Biological signals including blood pressure and heart rate measured under anesthesia were significantly different from those obtained under normal conditions. The stress of restraint in awake animals can also affect the accuracy of physiological evaluation. This paper details the surgery required to allow key cardiovascular parameters to be determined. The telemetric measurement of cardiovascular parameters such as blood pressure, heart rate, electrocardiograph(ECG) established. We carried out the continuous monitoring of cardiovascular parameters using the telemetry system in F344 rats. During the measurement, no significant changes were observed in the heart rate and blood pressure. ECG signals and body temperature were also constant during the measurement of biological signals. With the results of this study, we conclude that this telemetry system can be applied usefully for the assesment of biological parameters in the rats.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2009년도 정보 및 제어 심포지움 논문집
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• pp.138-140
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• 2009

Hemorrhage shock occupies high rate in trauma patient's mortality and blood pressure is the variance that judges early diagnosis and the effect of remedy. Systolic blood pressure is related to pulse transit time(PTT). PTT means the time that is required to flow from the heart to peripheral artery. PTT is influenced from the length, cross section and stiffness of the blood vessels. It is hard to evaluate the correlation between systolic blood pressure and PTT because they are variable in human body. In this paper, we evaluated the correlation between the systolic blood pressure and PTT in normal and hemorrhage states using standardized rat. PTT is defined as the time differences between the R peak and the peak of pulse wave. The analyzed time differences of ECG and blood pressure are analyzed every 5minutes for 30 seconds when there is before and after bleeding. Before bleeding, systolic blood pressure and PTT are steadily preserved but when the bleeding comes started, systolic blood pressure is declined. However PTT was increased and decreased. Under the circumstance that the standardized rat is controlled by age, the length of the blood vessels, and any disease, it shows that PTT measurement using systolic blood pressure of bleeding is impossible.

• 대한의용생체공학회:의공학회지
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• 제45권1호
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• pp.49-55
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• 2024

Accurate measurement of blood pressure is essential for classifying an individual's disease, identifying blood pressure-related risks, and managing health. Due to the environmental and health hazards of mercury sphygmomanometers, automatic sphygmomanometers using the oscillometric method are widely used in hospitals as well as in general homes, and have established themselves as a practical standard sphygmomanometer. In this study, we developed a blood pressure simulator using an actuator that provides simulated pressure to an automatic blood pressure cuff. The developed blood pressure simulator adopts an arm-shaped cylindrical shape similar to the situation in which a person measures blood pressure with an automatic blood pressure monitor, and implements a method of transmitting pressure to the cuff using a pressure plate. Accuracy was evaluated through the mean and standard deviation of the difference with the commercialized blood pressure simulator BP PUMP 2, and reproducibility was confirmed using two automatic blood pressure monitors. The developed blood pressure simulator enables automatic blood pressure monitoring in a simple manner and also meets the evaluation standards for accuracy and reproducibility. In the future, as a standardized blood pressure simulator, it is expected to be of great help in evaluating and verifying the performance of automatic blood pressure monitors by supplementing precise hardware and software and building a blood pressure database.

• 대한수의학회지
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• 제58권3호
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• pp.131-136
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• 2018

Blood pressure (BP) measurement plays a pivotal role in veterinary medicine for diagnosing cardiovascular disorders and monitoring anesthesia of animals. Although indirect BP measurement has been widely applied to monitor BP because of its convenience and non-invasiveness, it is still unclear whether indirect BP measurement is compatible with direct BP measurement in minipigs. In addition, the effect of animal posture during BP measurement is not well understood in minipigs despite its importance to cardiovascular performance. Therefore, both systolic and diastolic arterial BPs in minipigs were measured via femoral artery catheterization for direct BP measurement and using a compressive cuff as an indirect BP measurement under the dorsal or right lateral recumbent postures. Numerical values were processed by the Bland-Altman method to calculate the bias ${\pm}$ SD and the limits of agreement (LOA). In accordance with the American College of Veterinary Internal Medicine guidelines, the results between direct and indirect BP measurements were determined as apparent disagreements in both systolic and diastolic arterial BPs under all postures because of large bias ${\pm}$ SD and wide LOA. The results of the present will help prevent misinterpretation of the anesthetized patient's condition during monitoring of BP by indirect measurement.

• 센서학회지
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• 제24권4호
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• pp.239-246
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• 2015

Blood pressure is possible to diagnose a disease associated with blood pressure and judgment the current health of patients. Automatic blood pressure monitor capable of measuring a blood pressure easily in hospital and at home have become spread. In this study, we developed the blood pressure simulator (BPS) that can test the arm-type automatic blood pressure monitor that is commonly used in hospital. BPS is to produce a pressure similar to the pressure wave generated in the human blood using a servo disk motor. Then, using the silicon tube, it implements the situations such as human blood vessels, and to output the generated pressure waveform. Simply the BPS's phantom put on the cuff and it is able to simulate blood pressure. So anyone can quickly test the blood pressure monitor within one minute and it is possible to shorten the test time required for the automatic blood pressure monitor. In Performance test, the trends and the standard deviation of the values measured in the BPS is similar to the value of the measured pressure from people with normal blood pressure. Thus, the development BPS showed a possibility of taking into account the actual blood pressure measurement environment simulator.

• Journal of Nutrition and Health
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• 제27권2호
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• pp.181-191
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• 1994

This study was designed to evaluate anthropometric measurement, blood pressure, salt threshold and salt preference of children living at orphan home in Seoul and Kangnung. Anthropometric data of the subjects were slightly lower than the Korean standards, and those of children in Seoul were slightly higher than those of children in Kangnung. There were no differences in salt threshold and salt preference between Seoul and Kangnung. Blood pressure had positive correlation that partialled out of age with various anthropometric measurements(body weight, mid-arm circumference, girth of chest, BMI and body surface area), but did not correlated to salt threshold and salt preference.

• 기본간호학회지
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• 제3권1호
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• pp.96-107
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• 1996

Automated blood pressure monitors have gained acceptance in many clinical settings with the increasing demand, the accurate BP measuring devices reguire the need for validation. We have evaluated the Dinamap 8100, an oscillometric automated blood pressure monitor, using the Mercury sphygmomanometer as a reference. Comparison of sphygmomanometers was conducted 60 patients (30-Normotensive group, 30-Hypertensive group at Seoul National University Hospital. Two trained observers took measure blood pressure(systolic/diastolic) at the same time using the Dinamap 8100 on one arm and the Mercury on the other. For each measurement, the device was randomly selected from a group of devices repetively used for the experiment. Mean readings for systolic pressure with the Dinamap 8100 in normotensive group were lower(mean difference ; 4.26mmHg) than the Mercury type. Mean readings for systolic pressure with the Dinamap 8100 in hypertensive group were lower(mean difference ; 9.05mmHg) than the Mercury type. Mean readings for diastolic pressure with the Dinamap 8100 in normotensive group were lower (mean difference ; 7.46mmHg) than the Mercury type. Mean readings for diastolic pressure with the Dinamap 8100 in hypertensive group were lower(mean difference ; 9.03mmHg) than the Mercury type. We have found that blood pressure readings with the Dinamap 8100 were lower than those with the Mercury type. we are using the Mercury type in clinics, although it has observer bias and terminal digit preference. But the Dinamap 8100 is readily portable, simple to use, and capable of preventing observer bias and terminal digit preference. The Dinamap 8100 is acceptable for blood pressure determination in subjects who are normotensive or hypertensive ones.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2008년도 추계학술대회 논문집
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• pp.651-652
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• 2008

• Journal of Nutrition and Health
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• 제27권5호
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• pp.460-472
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• 1994

Prevalences of hypertension and obesity of primary school children in Kangnung were investigated, and the correlations between blood perssure and measured anthropometry were also studied to identify the factors that influence on blood pressure. 1,164 children (602 boys and 562 girls) from five elementary schools were chosen for this study. Anthropometric measurements were taken for blood pressure, body weight, height, triceps skinfold, and circumferences of chest and arm. Data of family history of hypertension were obtained by means of prepared questionnaires. Prevalences of hypertension were 3.3% in boys and 3.1% in girls. The group with elevated blood pressure had relatively a greater frequency of familial hypertension and significantly higher mean body weight and obesity index. The prevalence of obesity was defined as percentage of children whose rates of current weight to standard weight for height and sex in Korean children were more than 120%. Prevalence of obesity were 16.3% in boys, 10.3% in girls. There findings clearly revealed the influences of above-average weight and familial hypertension on blood pressure. These results suggest that children with familial hypertension should be avoid excess adiposity and be measured blood pressure regularly.

• Journal of Mechanical Science and Technology
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• 제18권6호
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• pp.1036-1041
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• 2004

A newly designed pressure-scanning slit viscometer is developed to combine an optical device without refraction while measuring blood viscosity over a range of shear rates. The capillary tube in a previously designed capillary viscometer was replaced with a transparent slit, which is affordable to mount optical measurement of flowing blood cells. Using a pressure transducer, we measured the change of pressure in a collecting chamber with respect to the time, p(t), from which the viscosity and shear rate were mathematically calculated. For water, standard oil and whole blood, excellent agreement was found between the results from the pressure-scanning slit viscometer and those from a commercially available rotating viscometer. This new viscometer overcomes the drawbacks of the previously designed capillary viscometer in the measuring whole blood viscosity. First, the pressure-scanning slit viscometer can combine an optical instrument such as a microscope. Second, this design is low cost and simple (i.e., ease of operation, no moving parts, and disposable).