• Korean Journal of Fisheries and Aquatic Sciences
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• v.49 no.5
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• pp.620-627
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• 2016

A 60-day experiment was conducted to determine the effect of feeding and starvation on the survival, growth, and blood parameters of red sea bream Pagrus major. The starved group was not fed during the first 32 days of the experiment and was then fed for 28 days. The growth rate of the starved fish group was significantly lower than that of the fed fish group. Starvation resulted in growth retardation and reductions in final body weight, growth rate, specific growth rate, and condition factor, whereas the fed fish group grew well and maintained a good condition. The growth rate of the starved group that was refed was higher than that of the fed group. Red blood cells, hematocrit, and hemoglobin showed no significant differences between the fed and starved groups. The cortisol and glucose levels of the fed group of juveniles were higher than those of the starved group. The cortisol levels of the starved group of adults were higher than those of the fed group, whereas the glucose levels of the starved group were lower than those of the fed group. These results suggest that the survival, growth, and hematological parameters used to reflect starvation and feeding in this study provide a useful index of physiological response and survival rate in red sea bream.

• Journal of Korea Game Society
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• v.17 no.4
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• pp.149-160
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• 2017

In 2016, we developed serious content for diabetes (Roly Poly 160) for diabetes, and then revised and supplemented them to serious game contents for self-care throughout diabetes, reflecting the needs of diabetes and health educators. We investigated the clinical efficacy. This study was one-group pretest-posttest design, 49 people with diabetes who were admitted to a hospital in the G region were given self-management training through 'Roly Poly 160' for 5 days, from February 27 to April 21, 2017, once a day. As a result of the study, the fasting blood glucose level and the postprandial blood glucose level of the subjects were significantly decreased (p<.000), and the self-efficacy and cognitive function were significantly increased (p<.000).

• Clinical Nutrition Research
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• v.13 no.1
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• pp.51-60
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• 2024

Obesity and overweight pose a significant public health problem, as they are associated with an elevated risk of metabolic syndrome (MetS). Several studies have shown that diet quality is associated with the development of MetS risk factors. Analyzing dietary patterns may be more helpful in determining the relationship between eating habits and chronic diseases compared to focusing on single foods or nutrients. In this study, our objective was to evaluate the association of food quality score (FQS) with risk factors for MetS in individuals with obesity and overweight. The participants in this cross-sectional study were 340 adults with overweight and obesity. Participants' food intake was measured using a Food Frequency Questionnaire, then the FQS was calculated. A fasting blood sample assessed serum glucose, triglycerides, total cholesterol (TC), high-density lipoprotein cholesterol, and serum insulin levels. Fat-free mass, height, basal metabolic rate, socio-economic score, and waist-to-hip ratio significantly differed among FQS tertiles. TC, systolic and diastolic blood pressure, and fasting blood glucose were significantly lower in the highest tertile of FQS. After multivariable adjustment, our results showed that individuals in the third tertile of FQS had reduced risk of higher levels of TC (odds ratio [OR], 0.982; 95% confidence interval [CI], 0.970-0.984) and higher levels of low-density lipoprotein cholesterol (OR, 0.974; 95% CI, 0.974-0.999). Our findings demonstrate an inverse relationship between diet quality, as measured by FQS, and MetS risk factors. However, further experimental and longitudinal investigations are warranted to elucidate the causal nature of this association.

• Korean Journal of Environmental Biology
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• v.33 no.4
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• pp.412-418
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• 2015

The objective of this study was to evaluate the effects of acute hypoxia on the physiological stress responses (plasma cortisol as the primary response, and hematocrit, hemoglobin, plasma glucose, sodium, chloride, osmolality, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) as the secondary responses) of Korean rockfish. The mortality in Korean rockfish started at $0.7mg\;L^{-1}$ and $0.8mg\;L^{-1}$ levels at $12^{\circ}C$ and $20^{\circ}C$, respectively. And the time required for the mortality in experimental fish was 274 and 148 minutes at $12^{\circ}C$ and $20^{\circ}C$, respectively. Levels of hematocrit, hemoglobin, AST, ALT, ion concentration, osmolality, glucose and cortisol had significantly increased with decreasing dissolved oxygen at $12^{\circ}C$ and $20^{\circ}C$.

• Women's Health Nursing
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• v.24 no.4
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• pp.367-378
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• 2018

Purpose: To examine effects of a postnatal care program on self-efficacy, self-management, and glycemic control in women with gestational diabetes mellitus (GDM). Methods: A non-equivalent control group non-synchronized quasi-experimental design was used. Sixty-two women with GDM were enrolled and assigned to either an experimental group (n=30) or a control group (n=32). The experimental group received an intervention which was postnatal care program for women with GDM. The postnatal care program for GDM included an individual education with leaflet and mobile web-based video with three times of telephone counseling. Effects of the intervention were measured with self-efficacy, self-management questionnaire, and a 75 g oral glucose tolerance test (75g OGTT). Statistical significance was examined using independent t-test and $x^2-test$. Results: Although there was no significant difference in 75g OGTT ($x^2=.11$, p=.748) or self-management (t=-1.28, p=.206), there was a statistically significant increase in self-efficacy (t=-2.02, p=.048) in the experimental group compared to that in the control group. Conclusion: A postnatal care program is needed for women with GDM to improve their self-efficacy. Further studies are warranted to improve self-management and glycemic control through tailored education for GDM postpartum women.

• Korean Journal of Health Education and Promotion
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• v.24 no.3
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• pp.1-19
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• 2007

Objectives: The purpose of the this study was to evaluate lifestyle intervention program for the treatment of the metabolic syndrome. Methods: Subjects of this study were 700 adults with metabolic syndrome who took health examinations in health promotion centers of Korea Association of Health Promotion between May 1 and June 30, 2006. Subjects were randomly assigned to an experimental group and a comparison group. Participants in the experimental group received intensive 3-month lifestyle modification intervention and participants in the comparison group received minimal information on lifestyle modification. Pre test and Post test were carried out to evaluate the effectiveness of the intervention program. Results: After the intensive intervention on lifestyle modification(healthy diet, physical activity, moderate drinking, stress management, and smoking cessation), the levels of blood pressure, waist circumference, fasting blood glucose and triglycerides were significantly reduced for those in experimental group(P<0.001). For those in comparison group, the levels of blood pressure(P<0.001), waist circumference(P<0.001), and triglycerides(P<0.01) were significantly reduced after the intervention. No change in the levels of high-density lipoprotein cholesterol were observed in both groups. After 3-month intervention, the prevalence of metabolic syndrome was reduced to 35.7% in experimental group and 48.5% in comparison group. Conclusion: This study has demonstrated the efficacy of therapeutic lifestyle intervention for the management of metabolic syndrome.

• Nutritional Sciences
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• v.5 no.4
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• pp.234-244
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• 2002

This study was conducted to compare the rates of hyperlipidemia, hypertension, high blood glucose, and liver dysfunction, between 64 obese children (24 boys and 11 girls who were moderately obese, and 21 boys and 8 girls who were severely obese) and 45 normal weight children (31 boys and 14 girls) from 13 elementary schools in Kangnung city. Among the boys with severe obesity, the levels of serum triglycerides and LDL-cholesterol (133.60 $\pm$ 49.99 mg/dl and 105.00 $\pm$ 41.12 mg/dl( respectively) were significantly higher compared to the normal Weight group (81.16 $\pm$ 23.59 mg/dl and 87.74 $\pm$ 32.095 mg/dl, respectively) of moderately obese group (102.30 $\pm$ 36.03 mg/dl, 89.99 $\pm$ 32.10 mg/이, respectively). In girls, only serum triglycerides were significantly higher in the severely obese group (154.30 $\pm$ 46.84 mg/dl), compared with the normal weight group (80.00 $\pm$ 25.31 mg/dl) or moderately obese group (106.40 $\pm$ 41.73 mg/dl). In boys, blood pressure in the severely obese group (systolic: 120.5 $\pm$ 9.74 mmHg; diastolic: 80.95 $\pm$ 10.44 mmHg) was significantly higher compared with the groups of normal weight or moderately obese children. The rate of hypertriglyceridemia was significantly different among normal weight, moderately obese, and severely obese boys (9.7%, 41.7%, and 76.2%, respectively). The proportion of boys who had an Atherogenic Index(AI) higher than 3 was found to be significantly higher in the severely obese group (28.6%), compared to 6.5% in the normal weight group and 4.1% in the moderately obese group. Among boys, a significantly higher rate of hypertension was found in the severely obese group, which showed high systolic blood pressure and high diastolic pressure (81.0% and 81.0%), compared with the normal weight group (16.1% and 22.6%) and moderately obese group (33.3% and 33.3%). In conclusion, the diagnosis and management of obese children needs to be tailored to gender and the degree of obesity. Furthermore, a systematic management program needs to be developed for early screening and detection of obesity in order to minimize the risk of hyperlipidemia and hypertension, especially in severely obese children.

• CELLMED
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• v.7 no.1
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• pp.4.1-4.4
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• 2017

Sogeunjung-tang (S-tang) is a traditional Korean medicine that has been used for the therapy of anxiety disorder in a variety of clinical situations. However, no study has investigated this effect. The aim of this study was to investigate the effectiveness of S-tang for reducing depression in animal model. The anti-depressant effect of S-tang was investigated in ICR mice by using forced swimming test (FST). After FST, we analyzed the blood biochemical parameters from blood. The immobility time was significantly decreased in the S-tang oral administration or pharmaceutical acupuncture group compared with the control group at 14 days (p < 0.05). The anti-depressant effect of S-tang was higher than that of fluoxetine (a classical anti-depressant). S-tang or fluoxetine significantly decreased the creatine kinase and lactate dehydrogenase level compared with the control group (p < 0.05) but not glucose, protein, and blood urea nitrogen level. Further investigation of S-tang as a potential pharmacologic agent in the management of depression related anxiety is warranted.

• Journal of muscle and joint health
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• v.25 no.2
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• pp.75-83
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• 2018

Purpose: The purpose of this study is to investigate the effects of an 8-week aquatic exercise program on risk factors of metabolic syndrome and stress in women. Methods: This study employed a non-equivalent control group pretest-posttest design. A total of 35 patients were recruited through a community health center. The data were analyzed with the SPSS 22.0 version program, and the outcome variables were risk factors of metabolic syndrome including abdominal circumference, triglyceride, high density lipoprotein cholesterol, blood pressure, fasting blood glucose, and the level of stress. Results: There was no statistically significant differences in abdominal circumference, triglyceride, high density lipoprotein cholesterol, and blood pressure difference (post-pre) between the experimental and control group. However, there was a significant difference in the stress level. Conclusion: This study result support the beneficial effect of stress management in women on risk reduction for metabolic syndrome. Health professionals consider to develop strategy of the aquatic exercise program to reduce factors of metabolic syndrome.

• Archives of Obesity and Metabolism
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• v.2 no.2
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• pp.45-53
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• 2023

Despite the emergence of obesity as a significant public health concern, artificial sweeteners have made their way into various food products due to the perception, that they serve as substitutes for sugar. Artificial sweeteners are used to supposedly achieve weight management and health improvement. However, their efficacy and safety remain debatable. Commonly used artificial sweeteners include aspartame, acesulfame potassium, saccharin, and sucralose. This article discusses the effects of artificial sweetener consumption on weight loss, appetite regulation, blood glucose control, and gut microbiota. Research findings, concerning the consumption of artificial sweeteners and their association with body weight, have shown inconsistencies between randomized controlled trials and cohort studies. Studies, comparing artificial sweeteners to sugar, have reported no significant differences in satiety. Although artificial sweeteners have no calories, they can affect blood sugar levels through the cephalic phase insulin response. A recent study suggested that artificial sweeteners influenced the occurrence of diabetes. Due to limitations in the study design, excluding diabetes-influencing factors was not feasible. The evidence showed that artificial sweeteners harbored potential health risks, necessitating further investigation. According to recent studies, the consumption of artificial sweeteners was associated with gut microbiota changes and individual blood sugar responses. It is important to note that artificial sweeteners cannot be considered safe alternatives to sugar, and further research is required.