• Asian-Australasian Journal of Animal Sciences
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• 제25권11호
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• pp.1611-1616
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• 2012

The aim of the study was to evaluate the effect of sodium nitrate consumption on egg quality and quantity, and some blood parameters of native breeder hens of West Azerbaijan province. One hundred native hens were used from wk 25 to 32 of age. These birds were divided into two groups. One group was fed the control diet (CD) but the other fed the same diet supplemented with 4.2 g/kg sodium nitrate (ND). After 2 wks of adaptation, eggs were collected daily and egg mass and egg production were measured weekly for five weeks. To assess the egg quality parameters, two eggs from each replicate pen were collected for three consecutive days each week. At the end of experimental period (wk 32 of age), blood samples of 5 birds per replicate were collected from the wing vein into anticoagulant tubes. Dietary sodium nitrate didn't affect the egg production, shell stiffness, shell thickness and Haugh unit (p>0.05) but it decreased the both egg production and egg mass during the last three weeks (wks 30, 31 and 32) (p<0.05). Furthermore, a treatment effect was observed for yolk colour (p<0.05). Both the egg production and egg mass were increased over time (p<0.05). No significant treatment${\times}$time interaction was observed for egg weight, egg production and egg mass (p>0.05). No effect of time or treatment${\times}$time were observed for shell stiffness (p>0.05). Over time, shell thickness was decreased while Haugh unit increased (p<0.05). None of the blood TP and TG or the activity of ALT, AST and LDH enzymes were affected by dietary consumption of sodium nitrate at wk 32 of age (p>0.05). Sodium nitrite decreased both the TAC and TC at wk 32 of age (p<0.001). It was concluded that the lower body antioxidant capacity of nitrate fed birds resulted in the lower performance (egg weight, egg production and egg mass).

• Asian-Australasian Journal of Animal Sciences
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• 제20권3호
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• pp.365-372
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• 2007

This study was conducted to determine effects of salinomycin (SL) on feeding-induced changes in glucose kinetics and blood VFA concentrations in sheep fed a high-roughage diet. Four sheep were fed the diet with or without 20 mg/kg diet of SL once daily for 21 d. Glucose entry and utilization rates were determined during the prefeeding and 3 h postfeeding periods, using a [$^{13}C_6$]glucose dilution method and non-steady state equations. Ruminal characteristics and concentrations of blood VFA, plasma glucose and insulin were also measured during the same periods. A feeding-induced increase in ruminal total VFA concentration tended to be inhibited (p<0.10) with SL, although ruminal pH was unaffected (p>0.10) with SL or by feeding. Salinomycin decreased (p<0.05) acetate proportion and increased (p<0.05) propionate proportion in the rumen, but did not modify these changes in response to feeding (p>0.10). A feeding-induced increase in blood acetate concentration was attenuated (p<0.05) with SL. Salinomycin tended to increase (p<0.10) blood propionate concentration without modifying its response patterns to feeding (p>0.10). Plasma concentrations of glucose or insulin were unaffected (p>0.10) with SL. Salinomycin tended to enhance (p<0.10) glucose entry and utilization rates. Feeding also enhanced (p<0.01) both rates, whereas their interactive effect was not detected (p>0.10). We conclude that SL possibly enhances whole body glucose entry and utilization with an increase in blood propionate concentration in sheep given a high-roughage diet, although SL does not appear to affect their responses to feeding.

• 대한의용생체공학회:의공학회지
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• 제23권4호
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• pp.281-286
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• 2002

심혈관계에서 자주 발생하는 죽상경화증과 혈전의 발생 및 성장에 관한 복잡한 기전을 이해하기 위하여 뇌의 혈액공급을 담당하는 경동맥을 2차원 축대칭으로 모사하여 수치해석하였다. 박동유동 상태에서 경동맥 내에 25%. 50%, 75%의 협착이 형성된 경우에 대하여 혈관내의 속도분포 및 혈류역학적 벽 파라미터들이 고찰되었다. 혈액은 뉴턴유체 및 전단변형률에 따라 점성이 변화하는 비뉴턴유체로 간주되었으며 비뉴턴모델로는 혈액과 유사한 점성치를 나타내는 Carraeu-Yasuda 모델이 적용되었다. 해석 결과 혈관내벽에 작용하는 벽전단응력은 협착이 커질수록 크게 증가하였으며 비뉴턴유체보다 뉴턴유체의 경우에서 벽전단응력이 크게 평가되었다. 벽전단응력 진동지표(OSI)에 의해 시간평균 재부착점이 예측되었는데 비뉴턴유체보다 뉴턴유체의 경우에서 협착 영역으로부터 멀리 떨어진 곳에서 관찰되었다. 시간평균 벽전단응력구배(WSSG)도 협착이 큰 경우에 상당히 크게 나타났는데 비뉴턴유체보다 뉴턴 유체의 경우에 더 큰 값이 나타났다.

• 한국식품저장유통학회지
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• 제23권5호
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• pp.753-757
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• 2016

본 연구에서는 도축장에서 폐수 처리되는 돈혈을 활용하여 단백질 분해 효소 처리를 하여 철분함량 및 용해도가 높은 철분분말을 제조하고자 하였다. 철분함량을 높이기 위하여 효소처리 및 혈액 분리 정도에 따른 돈혈 분말의 품질특성을 분석하였고, 그 결과 수급 받은 돈혈의 전혈에 Thermoase 0.2%를 첨가한 후 $60^{\circ}C$에서 4시간 처리하여 여과, 열풍건조처리를 하였을 때 철분함량이 110.00 mg/100 g 으로 가장 높은 것으로 확인되었으며, 재수화성 역시 높은 것을 확인하였다. 또 철분 보조제로써 활용 가능 여부를 확인하기 위하여 최종조건에 따라 제조 된 돈혈분말의 생체이용률을 측정하였으며, 대표적인 시중 판매 제품 보다 2.9배 높은 것으로 확인 되었다. 따라서 영양학적 가치가 있는 돈혈을 활용하여 철분분말을 제조한다면, 수입에 의존하고 있는 철분시장에 국내산 천연재료 공급이 가능할 뿐만 아니라 이의 폐기처리로 인한 비용처리 및 환경오염을 줄일 수 있을 것으로 기대된다.

• Journal of Korean Biological Nursing Science
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• 제19권4호
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• pp.215-226
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• 2017

Purpose: The purpose of this study was to investigate the effects of general, health, and alcohol-related characteristics on blood pressure and stress according to the Alcohol Use Disorders Identification Test (AUDIT). Methods: This was a descriptive study. From participants in the 2013 Korea National Health and Nutrition Examination Survey, 319 participants who responded to the survey when they were attending college or university were selected. Data were analyzed using the SPSS Win 23.0 program for composite sample data reflecting the composite design elements of stratification, colonization, and weighting. Results: Mean age of onset of alcohol drinking was $17.91{\pm}0.16$ years, the average AUDIT score was $7.56{\pm}0.41$, and 25 (9.1%) participants fell into the high-risk drinking group. In the high-risk AUDIT group, systolic blood pressure was influenced by age, gender, institution, health status, body mass index, and suicidal ideation, and the explanatory power of the model ($R^2$) was 75.0%. For diastolic blood pressure, institution and health status were the influential factors, and $R^2$ was 66.2%. Predictors of stress were health status, depression, and the age of onset of drinking, and $R^2$ was 57.2%. Conclusion: It was confirmed that the explanatory power of the variables in models of systolic and diastolic blood pressure and stress is greater in those with higher scores on AUDIT.

• 대한의용생체공학회:의공학회지
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• 제21권4호
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• pp.353-362
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• 2000

축류형 혈액펌프에서 발생하는 용혈이 이 펌프의 성공여부를 결정짓는 주요한 요인의 하나이다. 지금까지는 용혈을 알아내기 위해서는 in-vitro 적인 실험에 의하여 용혈량을 추정하였으나, 수치유체해석에 의한 용혈량의 추정이 가능하다고 생각된다. 따라서, 본 연구에서는 다양한 형태의 임펠러에 대하여, 난류모델은 k-$\varepsilon$모델을 사용하여 3차원 수치유체역학 해석을 시도하였다. 수치유체해석에 있어서는 펌프 유입측에 입자를 흘려 넣어 이 입자가 매일 10ms마다 받는 난류에너지를 구하여 전단응력으로 환산하였다. 해석결과 전단응력은 주로 임펠러의 후방에서 나타나는 것을 알 수 있었다. 수치유체해석결과의 신뢰성을 확인하기 위하여 임펠러의 in-vitro 실험에 의한 용혈시험 결과를 비교하였으나, 양자 사이에 상관도는 높은 것을 알 수 있었다. 상기한바와 같이 유체 해석에 의한 용혈 예측은 물론 용혈이 발생하는 주요 부위의 예측이 가능함을 시사하고 있어, 축류형 혈액펌프 개발시 용혈 특성 개선을 위한 설계도구로써의 유용함을 확인하였다.

• 대한의용생체공학회:의공학회지
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• 제24권4호
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• pp.301-307
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• 2003

본 연구에서는 한국형 인공심장의 혈액주머니 내 혈액 유동에 대한 수치적 해석 결과를 제시하였다. 혈액 유동은 2차원 비정상 유동으로 가정하였으며. 이를 해석하기 위하여 유한요소 기반의 상용코드인 ADINA를 사용하였다. 액츄에이터와 혈액주머니사이의 강체-고체 접촉, 그리고 혈액주머니와 혈류 사이의 고체-유체 상호작용을 모두 계산에서 반영하였다. 본 연구에서는 혈액주머니의 형상설계 과정에서 제시되었던 3가지 모델에 대해서 계산을 수행하고 이들의 혈류역학적인 적합성을 분석하였다. 계산결과에 의하면 혈액주머니의 수축 시는 출구로의 강한 흐름과 입구 부분에서의 정체영역이 관찰되었다. 이완 시에는 외부로부터 입구로 강한 혈류가 유입되고 있으며, 닫힌 출구에서 부근에서는 재순환 영역이 발생한다. 수축 시 전단응력은 출구 모서리 부근에서 극한값들을 가지게 되며, 이완 시에는 주로 입구 모서리와 액츄에이터 접촉면에서 최소, 최고치를 보여주고 있다.

• Journal of Nutrition and Health
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• 제46권2호
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• pp.126-136
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• 2013

This study was conducted in order to investigate the association between hypertension and oxidative stress-related parameters and to evaluate these parameters in subclinical hypertensive patients and normotensive subjects living in Korea. We attempted to determine whether oxidative stress-related parameters would differ between two groups of 227 newly-diagnosed, untreated (systolic blood pressure (BP) ${\geq}$ 130 mmHg and diastolic BP ${\geq}$ 85 mmHg) and 130 normotensive subjects (systolic BP < 120 mmHg and diastolic BP < 80 mmHg). General characteristics of the subjects were collected using a simple questionnaire. From subjects' blood, degree of DNA damage in lymphocytes, the activities of erythrocyte superoxide dismutase, catalase, and glutathione peroxidase, level of plasma total radical-trapping antioxidant potential (TRAP), glutathione, and anti-oxidative vitamins, as well as plasma lipid profiles and conjugated diene (CD) were analyzed. Evaluation of the associations of oxidative stress-related parameters with blood pressure of the subjects was performed using Pearson partial correlation and multivariate logistic regression analysis after adjusting for confounding factors. Several oxidative stress-related parameters were higher in subclinical hypertensive patients than in normotensive subjects. Plasma levels of ${\alpha}$-tocopherol, ${\beta}$-carotene, TRAP, and activity of GSH-px were significantly lower in subclinical hypertensive patients than in normotensive subjects. Increased levels of DNA damage, lipid peroxidation, triglyceride, total cholesterol, and LDL-cholesterol were observed in subclinical hypertensive patients. These results confirm an association between blood pressure and oxidative stress-related parameters and suggest that the pathogenic role of oxidative stress in hypertension might be significant.

• 한국유기농업학회지
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• 제28권4호
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• pp.627-641
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• 2020

Intensive farming methods that do not guarantee animal welfare can induce stress in pigs. Stress, in turn, can reduce their disease resistance and influence their hormones and metabolites in such a manner that productivity is negatively affected. This study was conducted to compare the stress related factors and blood characteristics of pigs raised on conventional farms and those raised on animal welfare farms. We measured the levels of cortisol, epinephrine and norepinephrine, biochemical parameters in blood and glycogen, L-lactate and heat shock protein 70 (HSP70) in muscle, as physiological markers of indicating the stress in conventional farm pigs (Control, n=10) and animal welfare farm pigs (Welfare, n=10). We found that there was a significant difference in the albumin-globulin ratio (A/G ratio), as well as the albumin (ALB), blood urea nitrogen (BUN) and aspartate aminotransferase (AST) levels between the two farms. Epinephrine was significantly higher in conventional farm, while level of norepinephrine was higher in animal welfare farm. There was no significant difference in cortisol, which is known as a stress hormone, across the two groups of farms. Muscular glycogen content was significantly high in animal welfare farm pigs. While L-lactate tended to be low in the animal welfare farm pigs, the difference between them and the conventional farm cohorts was not significant. HSP70 showed high levels of expression in conventional farm. Thus, we suggested that blood parameter results showed a stress response in the livers of conventional farm, and that catecholamine hormones, glycogen, L-lactate and HSP70 can be used as physiological factors of assessing animal welfare.

• 가정간호학회지
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• 제26권2호
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• pp.210-218
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• 2019

Purpose: The purpose of this study was to identify the nutritional status of elderly individuals according to their household types and to investigate the predictors of their nutritional status. Methods: This study, which was a descriptive research study, involved physical measurements, surveys, and biochemical tests in 87 elderly individuals living in the community. Using SPSS/Win 24.0, logistic regression analysis was performed to identify the general characteristics, blood pressure, body mass index (BMI), mini nutritional assessment (MNA) score, and biochemical indicators in elderly individuals according to the household type. Results: Elderly individuals living with family members had higher MNA scores than those of elderly individuals living alone, while showing lower levels of systolic blood pressure and fasting blood sugar. The results of the logistic regression analysis showed that the risk factors were MNA scores (odds ratio (OR)=1.81, 95% confidence interval (CI)=1.36-2.42), systolic blood pressure (OR=0.96, 95% CI=0.92-1.00), and fasting blood glucose (OR=0.94, 95% CI=0.90-0.99). Conclusion: It was confirmed that elderly individuals living alone need differentiated nutrition intervention, since the results showed that they had lower nutritional levels and improper nutritional management than that in elderly individuals living with family members.