• Bulletin of the Korean Chemical Society
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• v.22 no.5
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• pp.467-475
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• 2001

A triblock copolymer based on $poly(\varepsilon-caprolactone)$ (PCL) as the hydrophobic part and poly(ethylene glycol) (PEG) as the hydrophilic portion was synthesized by a ring-opening mechanism of ${\varepsilon}-caprolactone$ with PEG containing a hydroxyl group at bot h ends as an initiator. The synthesized block copolymers of PCL/PEG/PCL (CEC) were confirmed and characterized using various analysis equipment such as 1H NMR, DSC, FT-IR, and WAXD. Core-shell type nanoparticles of CEC triblock copolymers were prepared using a dialysis technique to estimate their potential as a colloidal drug carrier using a hydrophobic drug. From the results of particle size analysis and transmission electron microscopy, the particle size of CEC core-shell type nanoparticles was determined to be about 20-60 nm with a spherical shape. Since CEC block copolymer nanoparticles have a core-shell type micellar structure and small particle size similar to polymeric micelles, CEC block copolymer can self-associate at certain concentrations and the critical association concentration (CAC) was able to be determined by fluorescence probe techniques. The CAC values of the CEC block copolymers were dependent on the PCL block length. In addition, drug loading contents were dependent on the PCL block length: the larger the PCL block length, the higher the drug loading content. Drug release from CEC core-shell type nanoparticles showed an initial burst release for the first 12 hrs followed by pseudo-zero order release kinetics for 2 or 3 days. CEC-2 block copolymer core-shell type nanoparticles were degraded very slowly, suggesting that the drug release kinetics were governed by a diffusion mechanism rather than a degradation mechanism irrelevant to the CEC block copolymer composition.

• Journal of computational fluids engineering
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• v.16 no.3
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• pp.95-103
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• 2011

In the block type VHTR core, there are inevitable gaps among core blocks for the installation and refueling of the fuel blocks. These gaps are called bypass gap and the bypass flow is defined as a coolant flows through the bypass gap. Distribution of core bypass flow varies according to the reactor operation since the graphite core blocks are deformed by the fast neutron irradiation and thermal expansion. Furthermore, the cross-flow through an interfacial gap between the stacked blocks causes flow mixing between the coolant holes and bypass gap, so that complicated flow distribution occurs in the core. Since the bypass flow affects core thermal margin and reactor efficiency, accurate prediction and evaluation of the core bypass flow are very important. In this regard, experimental and computational studies were carried out to evaluate the core bypass flow distribution. A multi-block experimental apparatus was constructed to measure flow and pressure distribution. Multi-block effect such as cross flow phenomenon was investigated in the experiment. The experimental data were used to validate a CFD model foranalysis of bypass flow characteristics in detail.

• Bulletin of the Korean Chemical Society
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• v.23 no.6
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• pp.872-879
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• 2002

One of the improtant characteristics of core-shell type nanoparticles is the long-term storage and reuse as an aqueous injection solution when required. For this reason, reconstruction of lyophilized core-shell type nanoparticles is considered to be essential . BAB type triblock copolymers differ from AB type diblock copolymers, which contain the A block as a hydrophilic part and the B block as a hydrophobic part. by not being easily redistributed into phosphate-buffered saline (PBS, pH 7.4, 0.1 M). Therefore, lyophilized core-shell type nanoparticles of CEC triblock copolymer were reconstituted using a somication process with a bar-type sonicator in combination with a freezing-thawing process. Soncation for 30s only resuspended CEC nanoparticles in PBS; their particle size distribution showed a monomodal pattern with narrow size distribution. The bimodal size distribution pattern and the aggregates were reduced by further sonication for 120 s but these nanoparticles showed a wide size distribution. The initial burst of drug release was increased by reconstitution process. The reconstitution of CEC core-shell type nanoparticles by freezing-thawing resulted in trimodal distribution pattern and formed aggregates, although freezing-thawing process was easier than sonication . Drug release form CEC nanoparticles prepared by freezing-thawing was slower than from the original dialysis solution. Although core-shell typenanoparticles of CEC triblock copolymers were not easily performed. Cytotoxicity testing of core-shell type nanoparticles of CEC-2 triblock copolymers containing clonazepam (CNZ) was performed using L929 cells. Cytotoxicity of CNZ was decreased by incorporation into nanoparticles.

• Journal of Electrical Engineering and Technology
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• v.1 no.1
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• pp.58-62
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• 2006

We proposed a novel segment type switched reluctance motor (SRM) in which the segment core was embedded in aluminum (conductive metal) rotor block in order to increase the mechanical strength and easy manufacturing as well as to improve the performance characteristics and reduce the vibration and acoustic noise. This paper explains the operation principle and the drive system and shows the experimental results in comparison with the VR type SRM.

• Bulletin of the Korean Chemical Society
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• v.25 no.7
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• pp.1025-1030
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• 2004

A hybrid linear polymer-dendrimer block copolymer, poly(ethylene glycol)-block-poly(L-lysine) dendrimer, was synthesized and introduced to form polyionic complexes with DNA. The copolymer formed core-shell type nanoparticles with plasmid DNA. From dynamic light scattering experiments, the mean diameter of the polyplexes was observed to be 154.4 nm. The complex showed much increased water solubility compared to poly(L-lysine). The plasmid DNA in polyplexes was efficiently protected from the enzymatic digestion of DNase I. The cytotoxicity and transfection efficiency for 293 cells was measured in comparison with poly(Llysine).

• Proceedings of the KIEE Conference
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• 1995.11a
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• pp.21-23
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• 1995

The analysis of the thin lamination model of the wound core type transformer by FEM requires many region division and much calculationg time, and it has difficulty in calculation by modem computer. A new method which is simulated by a solid but anisotropic block with the magnetic permeabilities in the orthogonal dimension, is selected to account for the presence of the lamination.[1] Based on this equivalent anisotropic block model, we analyze the iron loss of the wound core type transformer by FEM, and compare the simulation results with the experimental results.

• Journal of computational fluids engineering
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• v.14 no.2
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• pp.59-67
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• 2009

An accurate prediction of the bypass flow is of great importance in the VHTR core design concerning the fuel thermal margin. Nevertheless, there has not been much effort in evaluating the amount and the distribution of the core bypass flow. In order to evaluate the behavior and the distribution of the coolant flow, a unit-cell experiment was carried out. Unit-cell is the regular triangular section which is formed by connecting the centers of three hexagonal blocks. Various conditions such as the inlet mass flow rate, block combinations and the size of bypass gap were examined in the experiment. CFD analysis was carried out to analyze detailed characteristics of the flow distribution. Commercial CFD code FLUENT 6.3 was validated by comparing with the experimental results. In addition, SST model and standard k-$\varepsilon$ model were validated. The results of CFD simulation show good agreements with the experimental results. SST model shows better agreement than standard k-$\varepsilon$ model. Results showed that block combinations and the size of the bypass gap have an influence on the bypass flow ratio but the inlet mass flow rate does not.

• Journal of the Korean housing association
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• v.24 no.3
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• pp.9-18
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• 2013

This paper aims to investigate the design characteristics of a single housing block which is increasing in urban areas. For the analysis, all cases of single block housing in Daejeon metropolitan city were gathered into a database. Main concerns were on the location and the physical characteristics. The results of this study were as follows; 1) single block housing has been increasing both in the new developed areas and the existing urban areas 2) their location has shifted from residential districts to semi-residential and commercial districts. For this reason, the size and density has been increasing 3) the slab block with the hall type and the exterior corridor type were general in residential districts, diverse ones, however, including the point tower type were increasing with unusual circulation types such as central corridor, central core, double corridor, and mixed type in semi-residential and commercial districts 4) there were 5 types of access systems, and especially the street access and the piloti access were increasing, which were related with the high density.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.55 no.5
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• pp.263-266
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• 2006

An optical microphone was developed using a dual-core multi-mode fiber block and a membrane type micromirror. The fiber block serves as a compact optical head, and the micromirror as a reflective diaphragm. The micromirror is designed to be suspended through a silicon bar connected t a frame, allowing for displacement induced by acoustic waves. The optical head is implemented by integrating two multi-mode fibers in a single block, and used to transfer light signals between it and the diaphragm. For the assembled microphone, its static characteristics were observed to reveal the operating point defined as the optimum distance between the optical head and the diaphragm. And its dynamic response was tested to exhibit a frequency bandwidth of 3 kHz with the variation of $\sim5dB$.

• Nuclear Engineering and Technology
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• v.56 no.6
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• pp.2388-2394
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• 2024

In our previous works, two different spherical burnable poison particles (BPPs) as B₄C and Gd₂O₃ in pin-in block type HTGR core had utilized to suppress the excess reactivity and to control long-term reactivity during the burnup period. In the present work, we performed the neutronic analysis of a prismatic HTGR operating at 850 ℃ with thermal power of 100 MW containing spherical and cylindrical BPPs and then studied the self-shielding effect of BPPs and shape effect. The calculations were performed when the surface area (1) or volume (2) of cylindrical BPPs equals to that of the spherical BPPs. The calculations showed that the neutronic parameters were slightly better for the second case than the first one, such as the excess reactivity of the reactor core at the beginning of the cycle were more suppressed, the core lifetime were more extended, and the fuel-burning were more efficiently. The neutron spectrum in each region of the cylindrical BBPs slightly differs than that of the spherical BPPs. Therefore, the self-shielding effect of BPPs on reactor core performance depends on the particle's geometrical shape.