• Title/Summary/Keyword: Block Division

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An Evaluation of Human Thermal Comfort and Improvement of Thermal Environment by Spatial Structure (공간 구조별 열쾌적성 평가와 열환경 개선방안)

  • Lee, Jung-A;Jung, Dae-Young;Chon, Jin-Hyung;Lee, Sang-Moon;Song, Young-Bae
    • Journal of the Korean Institute of Landscape Architecture
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    • v.38 no.5
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    • pp.12-20
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    • 2010
  • The purpose of this study is to evaluate human thermal comfort by spatial structure and to explore solutions to improve the thermal environment of a small urban space. The study site was Korea University campus. Thermal conditions were measured to evaluate the quality of the thermal environment in each type of space within the study site. Micrometeorology measurements, analysis of space characteristics for using fish-eye lens photography, and thermal comfort modeling through the use of collected meteorological data, such as temperature and humidity, were performed. Results showed that the level of thermal comfort for humans differs depending on the types of space within the study site. Thermal comfort is better in open spaces than enclosed in the aspect of radiative mean temperature, Predicted Mean Vote(PMV), and Physiologically Equivalent Temperature(PET). This fact is probably due to shadows or buildings or trees that may block solar radiation. Thus, it is necessary to consider the spatial arrangements of buildings and trees to enhance openness and ventilation in the space. Paving materials and exterior building materials should also be selected to lower the radiant temperature. Given these results, a quantitative evaluation on human thermal comfort could propose a way to plan user comfortable small urban spaces. Study methods used and results provided in the study can promote a better way for urban space planning direction to improve environmental quality.

Expression Analysis of Programmed Cell Death Genes in Porcine Parthenogenesis (돼지 단위생식란의 세포사멸 유전자 발현 양상에 관한 연구)

  • Son, Jong-Yoon;Kim, Sang-Hwan;Jung, Duk-Won;Ryu, Chun-Yeol;Yoon, Jong-Taek
    • Journal of Embryo Transfer
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    • v.30 no.3
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    • pp.239-248
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    • 2015
  • The nature of molecular mechanisms governing embryonic cell block is largely unknown, but recent reports have demonstrated that proper execution of programmed cell death is crucial for this process. The main objective of this study is to determine effects of programmed cell death on porcine oocytes development in vitro after parthenogenesis. Among the blastocysts matured in 3MA, MAP1LC3A and ATG5 RNA gene expression level increased in the order of Cyst < 3MA < RP. However, Casp-3 and TNF-r RNA gene expression level decreased in the order of RP < 3MA < Cyst. Expression of mTOR within the RP-cultured blastocyst was the most highly to the inner cell mass, while 3MA-cultured blastocyst showed very lowest expression in inner cell mass. The expression of mTOR showed a pattern opposite to that of MAP1LC3A. That is, its expression was the lowest in Cyst group. When the enzymatic activity of MMP-2 and MMP-9 was assessed in culture, the level of active MMP-9 was higher expression in the medium of each RP treatment group, with the level of another treatment group being relatively higher. Analyses of TIMP-2 and TIMP-3 revealed that their expression was higher in groups that did not receive RP treatment. More specifically, the level of TIMP-2 was not affected by Cyst treatment, while the level of TIMP-3 was higher in 3MA and RP treatment group. There was highly cell division activation efficiency of parthenogenesis on cultured system of RP supplement IVC medium. Therefore, these results suggest that embryo development was significantly increased in conditional culture medium with active autophagy as compared to common cultured condition. Further investigation of this distinction may enable the development of innovative improvements for the production of porcine somatic cell nuclear transfer.

Growth and Ground Coverage of Ophiopogon japonicus 'Nanus' under Different Shade Conditions (차광처리에 따른 애기소엽맥문동의 생장과 피복에 관한 연구)

  • Kang, Ae-Ran;Park, Seok-Gon
    • Journal of the Korean Institute of Landscape Architecture
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    • v.45 no.2
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    • pp.68-75
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    • 2017
  • Demand for dwarf mondo grass (DMG; Ophiopogon japonicus 'Nanus') as an ornamental garden plant is expected to grow in the future. The purpose of this study was to investigate the levels of shade tolerance and ground cover by growing DMG under a variety of shade conditions for 18 months (May 2015~October 2016). DMG plants grown in bare ground for 3 years in Jangheung-gun, Jeonnam were used for testing. In an experimental site created in Naju city in Jeonnam, the DMG was planted in planters ($70cm{\times}70cm{\times}24cm$) and covered with a shading curtain to block natural light. Shaded conditions were then arranged under different levels of shade (0%, 55% and 75%). When the plants were grown, growth (leaf size, the number of leaves, fresh weight and dry weight) and ground coverage of DMG were analyzed. According to the results, DMG growth in terms of leaf size and the number of leaves was statistically higher under zero shade (full sunlight), when compared to other shaded conditions. DMG's fresh and dry weights were significantly greater under 0% and 55% shade, compared to those under 75% shade. The degrees of shade tolerance required for normal growth of DMG were found in the range of 0~50%, meaning that more than 50% shade may decrease plant growth. There were no statistical differences in ground coverage rates of DMG under different levels of shade. When 220 tillers were planted per $1m^2$ of plot, up to 80% of the area was covered by DMG after 18 months. Since DMG requires nutrient-rich soil to grow, sufficient nitrogen fertilizers are proposed to accelerate the ground cover of DMG. As DMG remained alive over the winter in the experiments, this study also suggests that DMG can be planted in the southern temperate region.

Evolution of corporate social contribution activities in the era of the Fourth industrial revolution (4차 산업혁명 시대의 기업사회공헌 활동의 진화)

  • Kim, Minseok;Cho, Youngbohk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.1
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    • pp.85-95
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    • 2019
  • Recently, studies on the fourth industrial revolution have been actively conducted in the areas of government, business, and academia. Corporate business models that utilize the major agendas of the fourth industrial revolution such as robots, artificial intelligence, Internet of things (IoT), and block chains have been created, and various changes have occurred in not only business, education, and living environments but also in international relations. In this study, we looked at changes in social contribution activities from the perspective of a company facing impacts of the fourth industrial revolution. This study examines the definition and activities of corporate social contribution and how we can contribute to society through corporate activities. 'AT Educom', LG Uplus 'Social Contribution through IoT', KT's anti-infectious disease prevention platform and cases of Intel using IoT. In addition, we have presented what we need to do in the future to promote corporate social contribution activities that will make more meaningful impacts on how corporate social contribution activities will change according to technology development. The first, measuring the performance of corporate social contribution activities needs a standardized methodology and social contribution activities through platform business and ICT should be actively pursued. Lastly, social contribution activities between companies and sectors will increase.

A Study on Court Auction System using Ethereum-based Ether (이더리움 기반의 이더를 사용한 법원 경매 시스템에 관한 연구)

  • Kim, Hyo-Jong;Han, Kun-Hee;Shin, Seung-Soo
    • Journal of Convergence for Information Technology
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    • v.11 no.2
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    • pp.31-40
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    • 2021
  • Blockchain technology is also actively studied in the real estate transaction field, and real estate transactions have various ways. In this paper, we propose a model that simplifies the authentication procedure of auction systems using Ethereum's Ether to solve the problem of offline court auctions. The proposed model is written in Ethereum's Solidity language, the court registers the sale date and the sale date with the DApp browser, and the bidder accesses the address of the individual's wallet created through Metamask's private key. The bidder then selects the desired sale and enters the bid price amount to participate in the auction. The bidder's record of the highest bid price for the sale he wants is written on the Ethereum test network as a smart contract. and creates a block. Finally, smart contracts written on the network are distributed by the court auction manager to all nodes in the blockchain network, and each node in the blockchain network can be viewed and contract verified. As a result of analyzing the smart contracts of the proposed model and the performance of the system, there are fees incurred due to the creation and use of Ether on platforms using Ethereum, and participation. Ether's changes in value affect the price of the sale, resulting in inconsistent fees in smart contracts each time. However, in future work, we issue our own tokens to solve the market volatility problem and commission problem with the value change of Ether, and refine complex court auction systems.

Anesthetic efficacy of supplemental buccal infiltration versus intraligamentary injection in mandibular first and second molars with irreversible pulpitis: a prospective randomized clinical trial

  • Zargar, Nazanin;Shojaeian, Shiva;Vatankhah, Mohammadreza;Heidaryan, Shirin;Ashraf, Hengameh;Baghban, Alireza Akbarzadeh;Dianat, Omid
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.22 no.5
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    • pp.339-348
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    • 2022
  • Background: To compare the anesthetic efficacy of supplemental buccal infiltration (BI) (1.7 ml) versus intraligamentary (IL) injection containing 0.4 ml of 4% articaine with 1:100.000 epinephrine after an inferior alveolar nerve block (IANB) with 1.7 ml 2% lidocaine in the first and second mandibular molars diagnosed with irreversible pulpitis (IP). Methods: One hundred subjects diagnosed with IP of either the mandibular first (n = 50) or second molars (n = 50) and failed profound anesthesia following an IANB were selected. They randomly received either the IL or BI techniques of anesthesia. Pain scores on a 170 mm Heft-Parker visual analog scale were recorded initially, before, and during supplemental injections. Furthermore, pulse rate was measured before and after each supplemental injection. During the access cavity preparation and initial filing, no or mild pain was assumed to indicate anesthetic success. The chi-square test, Mann-Whitney U test, and independent samples t-test were used for the analyses. Results: The overall success rates were 80% in the IL group and 74% in the BI group, with no significant difference (P = 0.63). In the first molars, there was no significant difference between the two techniques (P = 0.088). In the second molars, IL injection resulted in a significantly higher success rate (P = 0.017) than BI. IL injection was statistically more successful (P = 0.034) in the second molars (92%) than in the first molars (68%). However, BI was significantly more successful (P = 0.047) in the first molars (88%) than in the second molars (64%). The mean pulse rate increase was significantly higher in the IL group than in the BI group (P < 0.001). Conclusions: Both the IL and BI techniques were advantageous when used as supplemental injections. However, more favorable outcomes were observed when the second molars received IL injection and the first molars received BI.

Model-based Design and Verification of High-lift Control System Using a Performance Analysis Model (성능해석 모델을 활용한 고양력 제어시스템의 모델기반 설계 및 검증)

  • Cho, Hyunjun;Kim, Taeju;Kim, Eunsoo;Kim, Sangbeom;Lee, Joonwon
    • Journal of Aerospace System Engineering
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    • v.16 no.2
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    • pp.49-62
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    • 2022
  • The purpose of this paper was to present a model analysis-based design process and verification results for the high-lift control system of aircraft. For this, we used Matlab/Simulink, one of the most widely-used physical modeling tools. The high-lift control system can be divided into three domains. (i.e., Electronic control domain, Hydraulic actuation domain, and Mechanical power transmission domain) Based on this division, we modeled each of the major domains and sub-components, and integrated them to complete the complicated system model. During the development process, each model block was tuned by referring to the results of pre-test and parts acceptance tests. As a result, the entire performance model and the developed system were completely verified, through unit components and system integrated performance tests. Finally, we summarize the process and results applied to the design process of high-lift control system and present future work.

Anti-atopic dermatitis effects of Parasenecio auriculatus via simultaneous inhibition of multiple inflammatory pathways

  • Kwon, Yujin;Cho, Su-Yeon;Kwon, Jaeyoung;Hwang, Min;Hwang, Hoseong;Kang, Yoon Jin;Lee, Hyeon-Seong;Kim, Jiyoon;Kim, Won Kyu
    • BMB Reports
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    • v.55 no.6
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    • pp.275-280
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    • 2022
  • The treatment of atopic dermatitis (AD) is challenging due to its complex etiology. From epidermal disruption to chronic inflammation, various cells and inflammatory pathways contribute to the progression of AD. As with immunosuppressants, general inhibition of inflammatory pathways can be effective, but this approach is not suitable for long-term treatment due to its side effects. This study aimed to identify a plant extract (PE) with anti-inflammatory effects on multiple cell types involved in AD development and provide relevant mechanistic evidence. Degranulation was measured in RBL-2H3 cells to screen 30 PEs native to South Korea. To investigate the anti-inflammatory effects of Parasenecio auriculatus var. matsumurana Nakai extract (PAE) in AD, production of cytokines and nitric oxide, activation status of FcεRI and TLR4 signaling, cell-cell junction, and cell viability were evaluated using qRT-PCR, western blotting, confocal microscopy, Griess system, and an MTT assay in RBL-2H3, HEK293, RAW264.7, and HaCaT cells. For in vivo experiments, a DNCBinduced AD mouse model was constructed, and hematoxylin and eosin, periodic acid-Schiff, toluidine blue, and F4/80-staining were performed. The chemical constituents of PAE were analyzed by HPLC-MS. By measuring the anti-degranulation effects of 30 PEs in RBL-2H3 cells, we found that Paeonia lactiflora Pall., PA, and Rehmannia glutinosa (Gaertn.) Libosch. ex Steud. show an inhibitory activity of more than 50%. Of these, PAE most dramatically and consistently suppressed cytokine expression, including IL-4, IL-9, IL-13, and TNF-α. PAE potently inhibited FcεRI signaling, which mechanistically supports its basophil-stabilizing effects, and PAE downregulated cytokines and NO production in macrophages via perturbation of toll-like receptor signaling. Moreover, PAE suppressed cytokine production in keratinocytes and upregulated the expression of tight junction molecules ZO-1 and occludin. In a DNCB-induced AD mouse model, the topical application of PAE significantly improved atopic index scores, immune cell infiltration, cytokine expression, abnormal activation of signaling molecules in FcεRI and TLR signaling, and damaged skin structure compared with dexamethasone. The anti-inflammatory effect of PAE was mainly due to integerrimine. Our findings suggest that PAE could potently inhibit multi-inflammatory cells involved in AD development, synergistically block the propagation of inflammatory responses, and thus alleviate AD symptoms.

Rock Bolt Integrity Assessment in Time-Frequency Domain : In-situ Application at Hard Rock Site (유도파를 이용한 시간-주파수 영역 해석을 통한 록볼트 건전도 실험의 경암지반 현장 적용성 평가)

  • Lee, In-Mo;Han, Shin-In;Min, Bok-Ki;Lee, Jong-Sub
    • Journal of the Korean Geotechnical Society
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    • v.25 no.12
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    • pp.5-12
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    • 2009
  • As rock bolts become one of the main support systems in tunnels and underground structures, the integrity of the rock bolts affects the safety of these structures. The purpose of this study is the evaluation of rock bolt integrity using wavelet transforms of the guided ultrasonic waves by using transmission test in the field. After several rock bolts with various defect ratios are embedded into a large scale concrete block and rock mass, guided waves are generated by a piezo disk element and measured by an acoustic emission (AE) sensor. The captured signals are analyzed in the time-frequency domain using the wavelet transform based on a Gabor wavelet. Peak values in the time-frequency domain represent the interval of travel time of each echo. The energy velocities of the guided waves increase with an increase in the defect ratio. The suitable curing time for the evergy velocity analysis is proposed by the laboratory test, and in-situ tests are performed in two tunnelling sites to verify the applicability of rock bolt integrity tests performed after proposed curing time. This study proves that time-frequency domain analysis is an effective tool for the evaluation of the rock bolt integrity.

Performance analysis and prediction through various over-provision on NAND flash memory based storage (낸드 플래시 메모리기반 저장 장치에서 다양한 초과 제공을 통한 성능 분석 및 예측)

  • Lee, Hyun-Seob
    • Journal of Digital Convergence
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    • v.20 no.3
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    • pp.343-348
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    • 2022
  • Recently, With the recent rapid development of technology, the amount of data generated by various systems is increasing, and enterprise servers and data centers that have to handle large amounts of big data need to apply high-stability and high-performance storage devices even if costs increase. In such systems, SSD(solid state disk) that provide high performance of read/write are often used as storage devices. However, due to the characteristics of reading and writing on a page-by-page basis, erasing operations on a block basis, and erassing-before-writing, there is a problem that performance is degraded when duplicate writes occur. Therefore, in order to delay this performance degradation problem, over-provision technology of SSD has been applied internally. However, since over-provided technologies have the disadvantage of consuming a lot of storage space instead of performance, the application of inefficient technologies above the right performance has a problem of over-costing. In this paper, we proposed a method of measuring the performance and cost incurred when various over-provisions are applied in an SSD and predicting the system-optimized over-provided ratio based on this. Through this research, we expect to find a trade-off with costs to meet the performance requirements in systems that process big data.