• Journal of Animal Science and Technology
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• v.63 no.3
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• pp.520-530
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• 2021

This experiment was performed to verify whether dietary heat-killed Lactobacillus rhamnosus (LR) improves growth performance and modulates immune responses of weaned pigs. Ninety-six weaned pigs ([Landrace × Yorkshire] × Duroc; 6.95 ± 0.25 kg body weight [BW]; 28 d old) were randomly allocated to four treatments: 1) a basal diet without heat-killed LR (CON), 2) T1 (CON with 0.1% heat-killed LR), 3) T2 (CON with 0.2% heat-killed LR), and 4) T3 (CON with 0.4% heat-killed LR). Each treatment had six pens with four pigs (6 replicates per treatment) in a randomized completely block design. The heat-killed LR used in this study contained 1 × 10⁹ FU/g of LR in a commercial product. Pigs were fed each treatment for four weeks using a two-phase feeding program to measure growth performance and frequency of diarrhea. During the last week of this study, all diets contained 0.2% chromic oxide as an indigestible marker. Fecal sampling was performed through rectal palpation for the consecutive three days after the four adaptation days to measure apparent total tract digestibility (ATTD) of dry matter, crude protein, and gross energy (GE). Blood sampling was also performed on day 1, 3, 7, and 14 after weaning to measure immune responses such as serum tumor necrosis factor-α (TNF-α), transforming growth factor-β1 (TGF-β1), C-reactive protein (CRP), and cortisol. The heat-killed LR increased (p < 0.05) growth rate, feed efficiency, and ATTD of GE for overall experimental period compared with CON, but reduced (p < 0.05) post-weaning diarrhea. In addition, pigs fed diets contained heat-killed had lower concentrations of serum TNF-α (d 7; p < 0.05), TGF-β1 (d 7; p < 0.10), and cortisol (d 3 and 7; p < 0.05) than pigs fed CON. In conclusion, dietary heat-killed LR improved growth rate, modified immune responses of weaned pigs, and alleviated post-weaning diarrhea.

• Journal of the Korea Institute of Building Construction
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• v.21 no.5
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• pp.483-493
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• 2021

Urban overcrowding has created an explosive supply and demand for high-rise buildings. High-rise buildings are contributing to enhancing the image of the city by serving as focal points, but due to the stack effect, malfunction of elevator doors, difficulties in opening and closing the doors and windows of the outer wall, smoke and odors spreading to the upper floors, noise, energy loss, fire and pollutants have been causing various unexpected problems such as rapid spread of fire. This study classified high-rise buildings according to their vertical zoning, analyzed the causes of and solutions to the stack effect, and derived design and construction methods. Through the initial plan to block the outside air and securing airtightness through precise construction, we sought ways to secure the airtightness inside and outside the building by actively blocking the airflow from the lower floors. In addition, the facility solution can be a measure to reduce the specific phenomena caused by the stack effect, but it should only be applied to the minimum extent because the potential for secondary damage is high. This study emphasized the need for systematic stack effect management by suggesting design and construction measures for each vertical zoning of the causes and countermeasures of the stack effect. It is expected that this study will be helpful not only for design and construction, but also for building maintenance.

• Journal of Science and Technology Studies
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• v.18 no.3
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• pp.217-255
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• 2018

Bitcoin, which appeared in 2008, was merely a conceptual virtual currency, but it now enjoys the status as actual money. Bitcoin is an electronic money system that can be traded directly without a central trust institution. Thanks to the popularization of Bitcoin, blockchain technology has become a widespread concern. That technology is expanding not only the currency mechanism, but also a variety of other services. The possibility of a blockchain in relation to actual currency is ongoing. This paper investigates the technological characteristics and social construction of the blockchain by comparing the cases of Bitcoin, Namecoin, and MediBloc among blockchain applications. Namecoin emerged in 2013 is an attempt to replace the centralized Internet Domain Name System(DNS). There has been controversy over that current system for a long time, but replacing the already established system is not easy. Nevertheless, Namecoin has potential as an alternative. Meanwhile, MediBloc is an application that involves distributed management of medical data in South Korea. MediBloc claims that the key producers of medical data are patients themselves. This is to challenge to the question who is a knowledge producer of medical data. Through these three cases, it has discussed that blockchain technology does supports to form more democratic decision-making or simply provide a technical solution as automation. As a citizen, we can intervene in the realization of blockchains by presenting social agenda. This will be a method of the social construction of technology.

• Journal of Korean Neurosurgical Society
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• v.64 no.1
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• pp.100-109
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• 2021

Objective : Diffuse astrocytic tumour (DAT) is a diffuse infiltrative astrocytoma tumour accompanied by molecular parameters such as the presence or absence of isocitrate dehydrogenase (IDH) gene mutations. Ki-67 is a marker for DAT proliferation, while programmed death ligand 1 (PD-L1) indicates an immune evasion mechanism. This study aimed to analyze the correlation among mutant IDH1 R132H, Ki-67, and PD-L1 immunoexpression in the DAT. Methods : A cross-sectional study was carried out on 30 paraffin blocks of DAT cases. Paraffin block samples consist of grade II (n=14), grade III (n=8), and grade IV (n=8). In this study, the immunohistochemistry-staining of mutant IDH1 R132H, Ki-67, and PD-L1 were carried out to determine the frequency of DAT with IDH1 mutations. Results : Our study shown the frequency of IDH1 mutations in grade II 50.0% (7/14), grade III 37.5% (3/8), and grade IV 12.5% (1/8). Our study also showed a difference in Ki-67 and PD-L1 expression between each the degree of DAT histopathology (p=0.0001 and p=0.002, respectively). There was an association between both mutant IDH1 R132H, and Ki-67 with PD-L1 expression in DAT (p=0.0087 and p=0.0049, respectively). Conclusion : DAT with the mutant IDH1 is frequently observed in grade II and small number of grade III. The expression of wild type IDH1, Ki-67, and PD-L1 were found to be higher in high grade DAT (grade III and grade IV). There is a correlation between each of mutant IDH1 status and Ki-67 with PD-L1 expression in DAT.

• Journal of Industrial Convergence
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• v.19 no.1
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• pp.147-158
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• 2021

This study was conducted seven times from 2007 to the 2019 Women's World Handball Championships to analyze and strengthen the strength of the Korean women's handball team through the analysis of the top five countries' strengths. Among the 41 national teams participating in the World Women's Handball Championship, a total of five national teams, including the Netherlands, Norway, Russia, Spain, and France, were selected for the final study. Among the records provided by the International Handball Federation (IHF), the ranking was selected by analyzing the competition records of 41 participating countries, and technical statistics and frequency analysis were conducted using the SPSS/PC+ Ver21.0 program. based on the accumulated records of the top five women's handball competitions, handball attack and defense strategies that can make up for the inferiority in future physical conditions are needed and detailed follow-up studies are needed. Also, we hope to use it as a basic resource for improving the performance of Korean women's handball players and to play a key role in enhancing the level of women's handball at the 2021 Tokyo Olympics.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.32 no.6
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• pp.575-586
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• 2020

In this study, a two-dimensional hydraulic model test was conducted to examine the hydraulic phenomena that occur around the seawall when wave and wind coexist. Based on recent seawall repair and reinforcement examples, the experimental section was constructed under the condition of installing wave dissipation blocks on the safety surface of four different representative seawalls. Water level fluctuation, reflection, overtopping and wave pressure characteristics according to external force change were reviewed. It was confirmed that the top concrete shape of the seawall is the most important factor of the hydraulic characteristics that appear in front of the seawall, and the tendency is more pronounced when wind acts. Even in the case of vertical type seawall, when wind of 3 m/s~5 m/s occurs, the amount of overtopping increases to about 5%~12%. In the case of wave pressure, it was confirmed from the experimental results that the value increased from about 1.5 to 2.2 times in front of the top of concrete block. In addition, it was confirmed that when the shape of the seawall was different, the range of change in the hydraulic characteristics appeared larger. Therefore, when designing a seawall of a new shape, a more detailed review of the hydraulic characteristics should be accompanied based on these experimental results.

• Applied Chemistry for Engineering
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• v.31 no.6
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• pp.679-687
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• 2020

In this study, poly(ether-block-amide) (PEBAX)/zeolitic imidazolate framework-8 (ZIF-8)-polyetherimide (PEI), and PEBAX/amine-modified ZIF-8 (amineZIF-8)-PEI composite membranes were prepared by varying the contents of ZIF-8 and amineZIF-8. Also the gas permeability properties of N2 and CO2 were investigated for each composite membrane. The N2 and CO2 permeability of the PEBAX/ZIF-8-PEI composite membrane increased as the ZIF-8 content increased, while the CO2/N2 selectivity gradually decreased. In the case of the PEBAX/amineZIF-8-PEI composite membrane, the permeability of N2 decreased slightly, and CO2 increased till amineZIF-8 amount was 0.5 wt% and then decreased when the content increased further. The CO2/N2 selectivity was the highest with a value of 78.3 at 0.5 wt% of amineZIF-8. because the amine modification in the amineZIF-8 improves the compatibility between PEBAX and amineZIF-8, It seems that amineZIF-8 was evenly dispersed in PEBAX, which could be greatly influenced by the porousity of ZIF-8 and also the affinity of amine toward CO2.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.12
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• pp.65-76
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• 2018

Due to the rapid demographic and structural changes, Korea has faced a variety of social issues and quickly entered the aged society since the 2000s. In order deal with this reality, diverse types of welfare policies are emerging in the society as a whole. The government began to supply domestic public silver housing in 2016 to provide against the quickly growing aged society and now, the government is planning to supply approximately 50,000 housing by 2022 for quantitative growth of aged society, by selecting 1st and 2nd designated areas for the project additionally. This public retirement(silver) housing combines 'space' with 'service'. The lower floors are a public silver welfare Facilities and the upper floors are a housing spaces. This type of housing is to deal with requirements of rental housing residents by combining physical space with supporting service. Based on barrier-free design, the complex and unit house have safety handles and alarm bells in the bathroom, undulating washstands, bathroom sliding doors, corridor safety handles, and emergency safety exit lamps in each housing unit so the aged and the disabled can use easily and conveniently. Also, hand rails are installed and stepped pulleys are removed to promote convenience. Currently, the government is planning to increase the supply, focusing on low-income groups, such as beneficiaries of national basic livelihood and the working poor. Recognizing that the public retirement(silver) housing project is at its early stage, this study examined satisfaction, based on evaluations of real residents. This study aimed to obtain more empirical research data and apply them to public retirement(silver) house space analysis. For analysis, this study targeted Wirye public retirement(silver) housing and Magnolia public retirement(silver) housing that are in operation, and literature review, previous research review, and field survey were conducted to examine the present state. Using the questionnaires consisting of four large classification items; Block Layout, Housing Unit, Welfare Facilities, and Barrier-free Design, and sub-details, a survey was conducted to analyze residents' satisfaction. In conclusion, it is anticipated that this study would serve as basic research data about public retirement(silver) housing to increase continuously in future by analyzing public retirement(silver) housing spaces, on the basis of the analyzed data.

• Journal of Dental Anesthesia and Pain Medicine
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• v.20 no.6
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• pp.367-375
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• 2020

Background: Intraosseous anesthesia (IO) allows the anesthetic solution to be injected directly into the cancellous bone. The anesthetic solution immediately reaches the periapical region, and thus the axonal area of the nerve, where it can temporarily disable the sodium pump. The effect is felt almost without any time delay, and only a small amount of anesthetic solution is required. Methods: This study aims to investigate the efficacy of IO using the AnestoⓇ device after infiltration anesthesia (IA) and/or inferior alveolar nerve block anesthesia (IANB) failed to work in symptomatic irreversible pulpitis (hot tooth). The 33 patients included in the study were treated additionally with 1.7 ml articaine hydrochloride with 1:100,000 epinephrine hydrochloride (UltracainⓇ D-S, Sanofi-Aventis, Frankfurt, Germany) IO. Results: The electrical pulp test showed that 95.76% of the volunteers reacted positively to the combination of IANB or IA with the IO. In women, the additive IO was effective at 97.22%. In men, the IO led to pain elimination in 94.00% of cases. The duration of the IO was less than a quarter of an hour (13.03 min). The IO worked longer in women than in men (13.61 min vs. 12.33 min). Overall, more than every third tooth that needed trepanation was located in the posterior area of the mandible (36.4%). Treatment of hot teeth in this area was associated with an increased pulse rate and increased residual pain. There was a moderate correlation (Spearman-Rho [IRI] = 0.280) between the Visual Analog Scale (VAS) score and bone density, and a significant correlation (IRI = 0.612) between subjective residual pain and bone width. The IO resulted in a moderate, transient increase in the pulse rate by approximately 20 bpm. This is similar to the temporary increase in heart rate after conventional anesthesia techniques in non-preloaded patients and can be considered clinically irrelevant. Conclusion: IO with the AnestoⓇ device as an extension and deepening of local pain elimination is recommended for the treatment of hot teeth.

• Journal of Internet of Things and Convergence
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• v.8 no.6
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• pp.93-97
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• 2022

The purpose of this study is to suggest implications for early childhood SW·AI education considering the characteristics of early childhood education through a survey on SW·AI education in kindergartens. For this study, data were collected from 194 kindergartens through convenience sampling. The data was analyzed using frequency distribution, and it was found that 44% of kindergartens are conducting SW·AI education. 22% are conducting SW·AI education in the form of regular curriculum, and 70% are conducting SW·AI education in the form of special activities after school. SW·AI education was found to be conducted mainly by external instructors (97%) in the classroom (80%). For SW·AI education, block coding-based programs developed by companies such as Naver and the Clova were used, and all of these programs used programs and teaching aids in a package format, including teaching aids and materials developed by companies. 56% answered that they are not currently conducting SW/AI education, and lack of awareness on SW·AI education and lack of human/environmental infrastructure were the main factors. In order to realize SW·AI education considering the characteristics of early childhood education based on this survey, First, SW·AI education programs should be developed to develop play-centered computational thinking skills. Second, systematic teacher education at the national level should be conducted. Finally, the establishment of a department dedicated to early childhood SW·AI consisting of early childhood education experts and SW·AI education experts and financial support at the national level should be provided.