• Applied Microscopy
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• v.21 no.1
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• pp.63-76
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• 1991

Butylated hrdroxyanisole(BHA), a widely used food additive phenolic antioxidant, is known to inhibit cancer formations inducible with a wide variety of chemical carcinogens including aflatoxin $B_1(AFB_1)$. Thus, in the present study morphological characteristics underlying the hepatoprotective effects of BHA against $AFB_1$ inducible ultrastructural changes of hepatocytes have been examined. The obtained results are as follows : 1 . Livers obtained from rats treated with $AFB_1$ in vivo have been examined with transmission electron microscope. Among the many hepatocellular structural aberrations induced by $AFB_1$ treatment, the nuclear chromatins were found to be distributed irregularly('cap formation') and the nuclear membrane was found to be partially segregated. Furthermore, there were many lipid droplets, hyperplasia of smooth endoplasmic reticulum, dialated rough endoplasmic reticulum and, lysosomes arrested at various stages of its development. 2. Also, when $AFB_1$ was given in vitro to hepatocytes which have been isolated from untreated normal rats and examined under scanning electron microscope, there were much 'blobbing' phenomena resulting from cytoskeletal disturbances. 3. However, in the liver obtained from rats pretreated with BHA and then give the $AFB_1$, the observed morphological aberrations were in much reduced extent. Similarly, the BHA-hepatocytes had much decreased severity in the $AFB_1$ inducible blob formations.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.49.2-49.2
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• 2016

MIRIS Paschen-${\alpha}$ ($Pa{\alpha}$) Galactic Plane Survey (MIPAPS) presents the first whole Galactic plane (with the width of $-3^{\circ}$ < b < $+3^{\circ}$) map for the $Pa{\alpha}$ emission line. Many of $Pa{\alpha}$ features were detected more brightly than the previous observed $H{\alpha}$ features, and they coincide well with dense cloud regions. This means that newly detected $Pa{\alpha}$ blobs can indicate massive star forming regions (H II regions) screened by foreground clouds around Galactic plane. Anderson et al. (2014) presented the most complete Galactic H II region catalog based on WISE 12 and 22 um data. Of the cataloged sources, only ~20% have measured radio recombination line (RRL) or $H{\alpha}$ emission, and the rest are still candidate H II regions. At first, we compare the MIPAPS results with Anderson's H II region catalog for the Cepheus region (Galactic longitude from $+96^{\circ}$ to $116^{\circ}$). From this, we will investigate how much MIPAPS can supplement the catalog, and show MIPAPS scientific potential. After that, we plan to extend this work to the whole plane, and finally catalog MIRIS $Pa{\alpha}$ blob sources for the whole Galactic plane.

• The KIPS Transactions:PartD
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• v.15D no.4
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• pp.581-588
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• 2008

Old films or photographs usually have damages from physical or chemical effects, and the damage and digitalization make stain, scratch, scribbling, noise, and digital drop out in frames. Damages include global damage and local damage, and it is well known that local damage restoration is a main factor for improving image quality. Previous researches have focused on impairment localization (esp. for line scratch impairments) and restoration techniques for line scratch, dirt, blob, and intentional scratch. Inpainting is a key technique using partial derivatives to restore damages in images. It does not show good quality for the complex images because it is based on finite order for partial derivatives, and it takes much time complexity. In this paper, we present a modified inpainting scheme, where we use Sobel edge operator's and angle to compute isophotes, and compare our scheme with Bertalmio's scheme. We experiment our scheme with two old Korean films, and Simulation results show that our scheme requires smaller time complexity than Bertalmio's scheme with comparable reconstructed image quality.

• Journal of Fashion Business
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• v.7 no.5
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• pp.108-118
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• 2003

Surface properties, including the texture and the luster, of cotton fibers and yarns thereof play an important role in textile technology. The convolutions and the cross-sectional shape of the cotton fiber affect the fabric texture and the luster accordingly. Mercerization of the cotton fabric affects the luster, strength, and other properties of the fabric. In this study, the effect of mercerization was examined on the luster of the cotton fabric, together with the effect of polishing treatment. One of the traditional methods determining the fabric luster is the use of glossmeter or goniometric glossmeter. The use of glossmeter gives successful results in determining the gloss of rather flat and continuous surface such as plastic sheet, painted surface, or paper products. Since the textile fabrics have diverse surface structures and textures, these could be regarded as having three-dimensional surface. Such complexity imposes some difficulties for differentiating subtle surface luster properties of diverse textile fabrics. The advancement in the area of imaging technologies has enabled the micro-scale analysis of the surface textures and the fabric luster recently. Using a CCD camera, the surface luster images were taken at various incident illumination conditions. Microscale analysis, including the blob analysis, of the images could differentiate the subtle luster properties present in a group of cotton fabric samples comprising mercerized cotton fabric, non-mercerized cotton fabric, polished cotton fabric, and a 'standard' cotton fabric. The glossmeter measurement gave satisfactory but limited differentiation among the samples, whose luster differences are easily recognizable with visual observation, except for the mercerized cotton fabric sample and the non-mercerized cotton fabric. The microscale analysis of the fabric luster could, therefore, help understand the nature of diverse textile fabric luster.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.316-316
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• 2016

HyGIS는 DEM 기반의 수문지형처리를 중심으로 다양한 모형을 연계할 수 있도록 구성된 S/W 모음이다. 이는 한국건설기술연구원을 비롯한 다수의 기관 및 연구원들이 노력한 성과물이다. 본 연구는 기존 HyGIS 연구과정에서 도출된 성과물의 실용화 사업화를 위한 방안을 연구하였다. 이를 위하여 S/W 테스팅, 오픈소스 도입, 클라우드 컴퓨팅으로 나누어 접근하였다. 먼저 S/W의 테스팅에 있어서 기존 개발 소스코드는 블랙박스 테스트 방식의 동등 클래스 분할, 경계 값 분석 등 일부 모듈에 대한 단위 테스트와 제한적인 통합테스트가 수행된 바 있다. 보다 체계적인 테스트 단계로서 화이트박스 테스트 개념 중 문장/분기/조건 커버리지에 대하여 검토하였으며, 실제 소스코드 중 핵심 구간에 대한 적용 및 정량화를 통하여 현 수준을 객관적으로 진단하였고 보완 방안을 도출하였다. 오픈소스 적용을 위하여 QGIS, MapWindow 등 공간정보 분야의 최신 오픈소스 모듈을 비교 검토하였다. 적용 단계는 이를 기존 HyGIS S/W에 반영시키는 과정이며, S/W 관점에서는 컴포넌트 모듈의 대체라고 표현될 수 있다. 대규모의 전환 비용이 발생되므로 적용 후보에 대하여는 기능적 측면 뿐만 아니라 마이그레이션 비용과 중장기적인 유지보수 비용을 고려한 검토가 이루어 졌다. 한편 오픈소스 기술의 적용은 단순히 구성 요소 원가절감 측면만이 아닌, 중장기적 유지보수 체계 도모 및 지속가능한 생태계로의 전환에 더 큰 의의가 있다. 마지막으로 클라우드 컴퓨팅 기술의 적용 분야이다. HyGIS 입력 Data의 공급을 위한 인프라로서 자체 구축 인프라가 아닌 IaaS 클라우드인 Blob Storage 및 CDN을 시험 적용하였다. 클라우드를 활용함으로써 초기 비용을 최소화하고 합리적 비용으로 유연한 확장이 가능한(Scale Out, Scale Up) 구조를 취하게 되었다. 또한 입력 Data 공급 서버를 위한 Storage 측면만이 아니라 S/W의 배포에 있어서도 클라우드 컴퓨팅 기술을 활용하고자 시도하였다. 클라우드 기술을 활용하여 HyGIS S/W가 설치된 VM(Virtual Machine)자체를 임대하는 방식으로 시험 구성 되었다. VM에 대한 RDP 프로토콜 Access에 있어서 IP기반 접근 제어를 통하여 보안을 강화하는 방안을 실험하였으며, ISO 27001, ISO 27018 등 관련 보안 규정에 부합하는 서비스 제공이 가능하도록 검토하였다. 이러한 클라우드 VM방식 서비스를 통하여 Package형 S/W 뿐만 아니라 Subscription 방식의 서비스 제공 방식을 병행할 수 있다. 사용자에게는 S/W 설치 및 H/W Lock 구비 과정이 생략되는 이점이 있다.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.36 no.6
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• pp.525-534
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• 2018

Camera calibration is the process of determining the parameters such as the focal length of a camera, the position of a principal point, and lens distortions. For this purpose, images of checkerboard have been mainly used. When targets were automatically recognized in checkerboard image, the existing studies had limitations in that the user should have a good understanding of the input parameters for recognizing the target or that all checkerboard should appear in the image. In this study, a methodology for automatic target recognition was proposed. In this method, even if only a part of the checkerboard image was captured using rectangles including eight blobs, four each at the central portion and the outer portion of the checkerboard, the index of the target can be automatically assigned. In addition, there is no need for input parameters. In this study, three conditions were used to automatically extract the center point of the checkerboard target: the distortion of black and white pattern, the frequency of edge change, and the ratio of black and white pixels. Also, the direction and numbering of the checkerboard targets were made with blobs. Through experiments on two types of checkerboards, it was possible to automatically recognize checkerboard targets within a minute for 36 images.

• Nuclear Engineering and Technology
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• v.54 no.10
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• pp.3717-3723
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• 2022

For the first time, two-dimensional temporal behavior of the edge localized mode (ELM) filament is measured in the edge tokamak plasma with a multi-channel electrical probe array (MCEP). MCEP, which has 16 floating probes (4 × 4), is mounted at the far scrape-off layer (SOL) region in the KSTAR. An electron temperature and an ion flux are measured by sideband method (SBM), which can achieve two-dimensional measurements with high time resolution. Furthermore, temporal evolutions of the electron temperature and the ion flux are obtained during the ELM occurrence. In the H-mode period, short spikes from ELM bursts are observed in measured plasma parameters, and the trend is similar to that of typical Hα signal. Interestingly, when blob-like ELM filaments crash the probe, the heat flux is significantly higher in a local region of the probe array. The results show that our probe array using the SBM can measure the ELM behavior and the plasma parameters without the effect of the stray current caused by the huge device. This study can provide valuable data needed to understand the interaction between the SOL plasma and the plasma facing components (PFCs).

• The KIPS Transactions:PartB
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• v.17B no.1
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• pp.47-54
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• 2010

Old archived film shows two major defects: line scratch and blobs. In this paper, we present a design and implementation of an automatic video restoration system for line scratches observed in archived film. We use autoregressive (AR) image model because we can make stochastic and specifically autoregressive image generation process with our PAST-PRESENT model and Sampling Pattern. We designed locality maximizing scanning pattern, which can generate nearly stationary time-like series of pixels, which is a strong requirement for a stochastic series to be autoregressive. The sampled pixel series undergoes filtering and model fitting using Durbin-Levinson algorithm before interpolation process. We designed three-stage film restoration system, which includes (1) film acquisition from VHS tapes, (2) simple line scratch detection and restoration, and (3) manual blob identification and sophisticated inpainting scheme. We implemented film acquisition and simple inpainting scheme on Texas Instruments DSP board TMS320DM642 EVM, and implemented our AR inpainting scheme on PC for sophisticated restoration. We experimented our scheme with two old Korean films: "Viva Freedom" and "Robot Tae-Kwon-V", and the experimental results show that our scheme improves Bertalmio's scheme for subjective quality (MOS), objective quality (PSNR), and especially restoration ratio (RR), which reflects how much similar to the manual inpainting results.

• Korean Journal of Poultry Science
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• v.28 no.3
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• pp.267-274
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• 2001

The pineal gland of the bird occupies a key position in the phylogenetic evolution of this organ. Therefore, the purpose of this study was to investigate the developmental changes of the pineal gland during post-hatching period in Korean pheasant. The pheasants were sacrificed at 1-day-, 1-month-, 2-month-, and 6-month-old after hatching. The morphological characteristics of a pineal glands were determined in all pheasants using light microscope, and transmission electron microscope. Connective tissue originated from the capsule divided the pineal parenchyma into incomplete lobules. The parenchyma was consisted of pinealocytes and supportive cells. These parenchymal cells were arranged in the forms of solid lobules as well as incomplete follicles. At the follicular lumen, membraneous lamellar complexes and blob -like structures were present. Pinealocyte, a predominent cell type, had euchromatic nucleus, and showed the segmental organization. The bulbous apical portion had scanty free ribosomes and occasional cilia associated with basal bodies. The constricted neck, transitional portion from apical to pericarya had junctional complexes with adjacent supportive cells, and had microtubules. Cell body contained abundant mitochondria, well-developed Golgi complex, rough endoplasmic reticulum (RER) and free ribosomes. Basal processes extended from the base of the cell soma toward the basal lamina and contained 60∼90 nm dense cored vesicles. Supportive cells, another major type of the parenchyma, were characterized by the dense and elongated nucleus, and contained moderate number of mitochondria, RER, developed Golgi complex, free ribosomes and a few dense bodies in the perinuclear cytoplasm. Slender processes of supportive cells interposed between the pinealocytes and often bordered the basal region of the parenchyma. These results indicate that the pinealocytes of the pheasant are not rudimentary photoreceptor cells, and appear to have secretory function. Further studies will be required to confirm the morphological characteristics of pineal gland in adult pheasant during breeding and nonbreeding season.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.54-54
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• 2003

Prostate gland contains neuroendocrine cells (PNECs) are playing important roles in physiological and pathophysiological processes of the prostate gland. Here, we investigated the role of purinoceptors in PNECs freshly isolated from rat ventral prostate (RPNECs) that show immunoreactivity to chromogranin A. Fura-2 ratiometry revealed that ATP evokes both fast Ca$\^$2+/ influx and store Ca$\^$2+/ release in RPNECs. A whole-cell patch clamp study demonstrated fast inactivating cationic current activated by ATP or by ${\alpha}$,${\beta}$-MeATP, which was blocked by ATP-TNP. The activation of P2X inward current was tightly associated with a sharp increase in [Ca$\^$2+/]$\sub$c/. The presence of P2X1/3 subtypes were proved by RT-PCR analysis. For the stored Ca$\^$2+/ release, ATP and UTP showed similar effects, suggesting the dominant role or P2Y2 subtypes, also confirmed by RT-PCR. Both P2X (${\alpha}$,${\beta}$-MeATP) and P2Y (UTP) stimulation induced changes in the cell morphology (initial shrinkage and blob formation on the surface) reversibly. Exocytotic membrane trafficking events were monitored with the membrane-bound fluorescent dye, FM1-43 using confocal microscopy. In spite of the similar Ca$\^$2+/ responses, UTP was far less effective in triggering exocytosis than ${\alpha}$,${\beta}$ -MeATP. Since serotonin is reportedly stored in the secretory granule of PNECs, we directly examined whether the aforementioned agonists elicit release of serotonin using carbon fiber electrode-amperometry. In accordance with the results of FM1 -43 experiments, ${\alpha}$,${\beta}$-MeATP efficiently evoke serotonin secretion while not with UTP. In summary, the P2X-mediated Ca$\^$2+/ influx plays crucial roles in the exocytosis of RPNECs. Although a global increase in [Ca$\^$2+]$\sub$c/ might be related with the morphological changes, a sharp rise of [Ca$\^$2+/]$\sub$c/ in the putative sub-plasmalemmal ‘microdomains’ might be a decisive factor for the exocytosis.