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The Association between Medication Use for Dyslipidemia and Osteoporosis (국내 성인환자에서 이상지질혈증 약물치료와 골다공증 상관성)

  • Lee, Hansol;Kim, Jongyoon;Rhew, Kiyon
    • Korean Journal of Clinical Pharmacy
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    • v.31 no.4
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    • pp.278-284
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    • 2021
  • Background: Osteoporosis is a disease that affects the quality of life and imposes a high socioeconomic burden. Studies have reported that statins, a HMG CoA reductase inhibitor, have a positive or negative effect on osteoporosis. The purpose of this study was to analyze the correlation between statins and osteoporosis risk. Methods: We used the total patient sample data of the Health Insurance Review and Assessment Service (HIRA-NPS-2018). We analyzed the prevalence of osteoporosis in adult patients of Korea who were diagnosed with dyslipidemia and were prescribed statins at the same time. The odds ratio (OR) according to the intensity and type of statin was used to confirming the prevalence. Results: Among the 1,138,899 patients included in the study, 143,895 patients used statins and 27,524 patients (19.13%) were diagnosed with osteoporosis in the statin group. The OR value of statin group was 0.96 (95% CI 0.94-0.98), confirming that the prevalence of osteoporosis decreased, and a significant decrease was seen in all statin intensity. Some of the moderate-intensity statins rather increased the prevalence of osteoporosis, but atorvastatin and rosuvastatin obtained positive results at both medium- and high-intensity doses, and lovastatin, a low-intensity statin, showed the greatest reduction in the prevalence of osteoporosis. Conclusion: We found that the prevalence of osteoporosis was reduced in the statin group, and there was a constant correlation regardless of gender or age. However, a large, prospective, double-blind and randomized study is needed for a long period of time to demonstrate the effectiveness of statins.

A Case Study on the Experience of Verbal abuse among Athletes (선수의 언어폭력 경험 실태에 관한 사례연구)

  • Yoo, Hyun-Mee
    • The Journal of the Korea Contents Association
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    • v.22 no.4
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    • pp.570-578
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    • 2022
  • The purpose of this study is to investigate the reality of verbal violence by leaders in the sports field to inform the seriousness of the damage suffered by athletes and to prepare a starting point for social interest and intervention. To this end, in-depth interviews were conducted with seven players who experienced verbal violence by the leader, and a qualitative case study method was adopted for a multifaceted analysis of verbal violence. As a result, 14 detailed areas and 5 categories were derived. Taken together, the verbal violence of the leader experienced by the players occurred in ambiguous, repetitive, and closed situations and had a structure of passive response. Since verbal violence affects the victim's personal and social problems without leaving evidence against trauma or perpetrators, a close understanding of the atmosphere and environment of the site is considered essential for preparing fundamental measures. Based on the results of these case studies, attention and intervention should be urged through understanding of secretly conducted verbal violence, and close policies should be prepared to supplement the blind spots of verbal violence.

Effect of application of muscle energy technique on patients with chronic back pain aged 30~40 years (근에너지기법 적용이 30~40대 만성 허리통증 환자의 통증과 압통에 미치는 영향)

  • Park, Jae Cheol;Yoo, Jin Ho
    • Journal of Korean Physical Therapy Science
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    • v.28 no.3
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    • pp.66-75
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    • 2021
  • Background: The purpose of this study is to investigate the effect of muscle energy technique and stretching on pain and pressure pain fear-avoidance beliefs questionnaire in patients with chronic back pain aged 30~40 years. Design: Pretest-Posttest design: single blind. Methods: The subjects of this study were 30, 22 males and 8 females between the ages of 30 and 40 with chronic back pain. Each group consists of three groups of 10 people. Changes in back pain were observed using Korean version of Oswestry Disability Index (K-ODI), visual analogue scale (VAS), and fear-avoidance beliefs questionnaire (FABQ). And the change in tenderness was observed using digital pressure statistics. Changes between groups after 3 weeks were compared with those before the experiment using one way ANOVA to determine the changes after 3 weeks. And the change within the group was investigated using the paired t-test. Results: As a result of the experiment, there were significant differences in the group changes in K-ODI, VAS, FABQ, and pressure pain (p<0.05). And there was a significant difference in all items after 3 weeks compared to before the experiment (p<0.05). Conclusion: In patients with chronic back pain, the muscle energy technique and stretching gave a significant difference in pain and pressure pain, fear-avoidance beliefs questionnaire changes. And this result suggests the possibility of providing basic data for future research and clinical physiotherapy intervention.

Design and Function Analysis of Dust Measurement Platform based on IoT protocol (사물인터넷 프로토콜 기반의 미세먼지 측정 플랫폼 설계와 기능해석)

  • Cho, Youngchan;Kim, Jeongho
    • Journal of Platform Technology
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    • v.9 no.4
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    • pp.79-89
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    • 2021
  • In this paper, the fine dust (PM10) and ultrafine dust (PM2.5) measurement platforms are designed to be mobile and fixed using oneM2M, the international standard for IoT. The fine dust measurement platform is composed and designed with a fine dust measurement device, agent, oneM2M platform, oneM2M IPE, and monitoring system. The main difference between mobile and fixed is that the mobile uses the MQTT protocol for interconnection between devices and services without blind spots based on LTE connection, and the fixed uses the LoRaWAN protocol with low power and wide communication range. Not only fine dust, but also temperature, humidity, atmospheric pressure, volatile organic compounds (VOC), carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2), and noise data related to daily life were collected. The collected sensor values were managed using the common API provided by oneM2M through the agent and oneM2M IPE, and it was designed into four resource types: AE and container. Six functions of operability, flexibility, convenience, safety, reusability, and scalability were analyzed through the fine dust measurement platform design.

Qualitative Study for Barriers for Medication and Health Care Service Use among the Visually Impaired and Hearing Impaired in Korea (시각장애인 또는 청각장애인의 의료기관 이용 및 의약품 안전사용 저해요인 관련 심층면접조사)

  • Lee, Soo-Hyun;Choi, Minji;Han, Euna
    • Korean Journal of Clinical Pharmacy
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    • v.31 no.4
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    • pp.311-323
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    • 2021
  • Objective: The disabled are in a blind spot for obtaining information on drugs, and the pharmacies' counseling on drug use is centered on non-disabled people. Few studies have investigated the current statuses of drug use by type of disability. The purpose of this study is to understand the drug use by type of disability and by life cycle of visually impaired and hearing impaired in Korea. Methods: The study participants consisted of 16 people with visually impairments, 12 people with hearing impairments. One in-depth interview was conducted per participant, and each interview was recorded and documented. Results: Common barriers against safe medication and medical service uses across disability types are 'lack of consideration and service for the disabled, limited access to medical facilities due to disability, limited access to information regarding medication use, psychological anxiety about drug use and side effects, and inconvenience regarding COVID-19 epidemic. The specific factors were 'difficulties in identifying proper medicines and following prescribed dosages' in the case of visually impaired, and 'problems with sign language interpretation system' for the hearing impaired. Conclusion: Disabled people are hindered from using medicines properly due to various factors. Based on the content derived from this study, it is necessary to eliminate the inhibition factors and devise specific measures for the safety of each type of disorder such as developing a method for medication counseling considering disabilities and establishing communication support systems.

Factors affecting the satisfaction of persons with disabilities at community oral care centers (일부지역 장애인구강진료센터 이용 만족도에 미치는 요인)

  • Yoon, So-Ra;Lee, Jae-Ra;Choi, Eun-Young
    • Journal of Korean Dental Hygiene Science
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    • v.4 no.2
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    • pp.1-7
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    • 2021
  • Background: To identify the factors that affect the current status and satisfaction of people with disabilities at community oral care centers. Methods: A structured self-administered survey, including five questions on facility environment, five on usage procedure, four on medical skill, four on care cost, three on friendliness, and three on satisfaction, was administered to 218 residents of the G-disabled community care center. It comprised a Likert 5-point scale (strongly agree, 5 points; agree, 4 points; moderate, 3 points; disagree, 2 points; not at all, 1 point). The reliability of the measurement tool was 0.932 for Cronbach's α. Results: The evaluation of community oral care centers for the disabled showed that the environment was hygienic (4.42±0.73), reservation system was well maintained (4.18±0.95), and the dentist-in-charge was satisfied with the treatment (4.37±0.62). The participants agreed that the details were sufficiently explained (4.29±0.71). However, in terms of medical expenses, the score of "have fully heard the explanation of medical expenses and reductions" was 3.88±0.92. The factors affecting satisfaction were sex, final educational background in the facility environment, usage procedure, and medical skill. Conclusion: To increase the satisfaction of people with disabilities at community oral care centers, it is necessary to establish a facility environment and service according to the patients' need and increase the reduction or exemption benefits between different treatment cost categories. Oral health management policies for the disabled should be developed based on these factors, so that the oral care of vulnerable groups in blind spots can be maintained.

Preventive effects of ginseng against atherosclerosis and subsequent ischemic stroke: A randomized controlled trial (PEGASUS trial)

  • Kwon, Boseong;Song, Yunsun;Kim, Joong-Goo;Lee, Dongwhane;Lee, Sang-hun;Cho, Young-Keol;Kim, Jong S.;Suh, Dae Chul
    • Journal of Ginseng Research
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    • v.46 no.4
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    • pp.585-591
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    • 2022
  • Background: Korean Red Ginseng (KRG) extract has been shown to have beneficial effects in patients with atherosclerosis, suggesting that KRG extract may be effective in preventing subsequent ischemic stroke in patients with severe atherosclerosis. Methods: This double-blind, placebo-controlled trial randomized patients with severe atherosclerosis in major intracranial arteries or extracranial carotid artery, to ginseng group and placebo group. They were given two 500-mg KRG tablets or identical placebo tablets twice daily for 12 months according to randomization. The primary endpoint was the composite of cerebral ischemic stroke and transient ischemic attack during 12 months after randomization. The secondary endpoints were change in volumetric blood flow of the intracranial vessels and the incidence of newly developed asymptomatic ischemic lesions. Any adverse events were monitored. Results: Fifty-eight patients were randomized from June 2016 to June 2017, 29 to ginseng and 29 to placebo, and 52 (28 and 24, respectively) completed the study. One patient in the placebo group, but none in the ginseng group, experienced ischemic symptoms (p = 0.46). Changes in volumetric blood flow and the presence of ischemic brain lesions did not differ significantly in the two groups, and none of these patients experienced adverse drug reactions. Conclusion: Ginseng was well tolerated by patients with severe atherosclerosis, with these patients showing good compliance with ginseng dosing. Ginseng did not show significant effects compared with placebo, although none of the ginseng-treated patients experienced ischemic events. Long-term studies in larger patient populations are required to test the effect of ginseng.

Analysis of the effect of non-face-to-face online SW education program on the computational thinking ability of students from the underprivileged class (비대면 온라인 SW 교육 프로그램이 소외계층 학생의 컴퓨팅 사고력에 미치는 영향 분석)

  • Lee, Jaeho;Lee, Seunghoon
    • Journal of Creative Information Culture
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    • v.7 no.4
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    • pp.207-215
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    • 2021
  • As computational thinking has been noted as an important competency worldwide, SW education was introduced in the 2015 revised curriculum, and SW education has been applied to the curriculum from 2018. However, in a poor educational environment, the educationally underprivileged class is in the blind spot of SW education and is not receiving systematic SW education. Therefore, this study analyzed the effect of conducting a non-face-to-face SW online education program for 267 underprivileged elementary school students in education at a time when non-face-to-face online education was being conducted through the COVID-19 mass infectious disease. As a result of conducting the computational thinking ability test, which abstraction, problem decomposition, algorithm, automation, and data processing, before and after education, the overall score of computational thinking and the score of all five factors were statistically significantly increased(p<0.001). Among the five factors, there was the highest score improvement in data processing score. These results suggest that the non-face-to-face SW online education program is effective in improving the computational thinking ability of elementary school students from the educational underprivileged class.

Effect of red ginseng on visual function and vision-related quality of life in patients with glaucoma

  • Lee, Kwanghyun;Yang, Heon;Kim, Joo Yeon;Choi, Wungrak;Seong, Gong Je;Kim, Chan Yun;Lee, Jun Mo;Bae, Hyoung Won
    • Journal of Ginseng Research
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    • v.45 no.6
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    • pp.676-682
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    • 2021
  • Background: Red ginseng has been found to improve ocular perfusion and dry eye syndrome in glaucomatous eyes; however, its effects on visual function and vision-related quality of life have not been investigated. This study sought to evaluate the effects of red ginseng on visual function and vision-related quality of life in glaucoma patients using contrast sensitivity and a questionnaire. Methods: Participants were randomly assigned to two groups in this prospective, randomized, double-blind study: in one group, red ginseng was taken first, followed by a placebo, and in the other, placebo was taken first, followed by red ginseng. We measured and compared changes in contrast sensitivity and vision-related quality of life between the two groups. Contrast sensitivity was measured using OPTEC® 6500P, and vision-related quality of life was evaluated using the 25-item National Eye Institute Visual Function Questionnaire. One-way and two-way repeated measure analyses of variance were used for the comparison. Relationships between respective changes in dry eye syndrome and contrast sensitivity were also analyzed. Results: Daytime contrast sensitivity and ocular pain improved after the administration of red ginseng. Nighttime contrast sensitivity was improved in early or moderate glaucoma. Improved contrast sensitivity was not associated with improvement in dry eye syndrome. Conclusion: Red ginseng could improve contrast sensitivity and ocular pain in patients with glaucoma. The mechanism underlying improvement in contrast sensitivity appears to be associated with enhanced retinal perfusion or retinal ganglion cell function, but not dry eye syndrome.

The efficacy of low-level diode laser versus laser acupuncture for the treatment of myofascial pain dysfunction syndrome (MPDS)

  • Khalighi, Hamid Reza;Mortazavi, Hamed;Mojahedi, Seyed Masoud;Azari-Marhabi, Saranaz;Parvaie, Parvin;Anbari, Fahimeh
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.22 no.1
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    • pp.19-27
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    • 2022
  • Background: Myofascial pain dysfunction syndrome (MPDS) is the most common type of temporomandibular disorder. This study compared the efficacies of low-level diode laser therapy (LLLT) and laser acupuncture therapy (LAT) in the treatment of MPDS. Methods: This double-blind randomized controlled clinical trial included 24 patients with MPDS who were randomly divided into two equally sized groups. Patients in the LLLT group received 12 sessions of low-level diode laser irradiation applied to the trigger points of the masticatory muscles during 1 month. The same protocol was also used in the LAT group according to the specific trigger points. We measured pain intensity and maximum mouth opening in both groups at baseline, during treatment, and 2 months after treatment completion. Results: The pain intensities decreased from 6.58±1.31 to 0.33±0.65 and from 7.08 ± 1.37 to 0 in the LLLT and LAT groups, respectively. The maximum mouth openings increased from 32.25 ± 8.78 mm to 42.58 ± 4.75 mm and from 33 ± 6.57 mm to 45.67 ± 3.86 mm in the LLLT and LAT groups, respectively. Pain intensity (P = 0.839) and level of maximum mouth opening (P = 0.790) did not differ significantly between the groups. Conclusion: Our results showed similar efficacy between LLLT and LAT in the treatment of MPDS signs and symptoms.