• 한국콘텐츠학회논문지
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• 제10권7호
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• pp.81-87
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• 2010

본 논문에서는 현재 생물정보학 연구에서 가장 많이 사용하고 있는 BLAST의 문제점을 분석하고 이에 따른 해결책을 제시하기 위하여 그리드 컴퓨팅을 이용한 G-BLAST(Grid Computing을 이용한 Basic Local Alignment Search Tool)를 제안한다. 본 연구에서 제안하고 있는 G-BLAST을 이용한 시스템은 이기종 분산 환경에서 수행이 가능한 서열분석 통합 소프트웨어 패키지이며 기존 서열분석 서비스의 취약점인 검색 성능을 개선하여 BLAST 검색 기능을 강화 하였다. 또한, BLAST 결과를 사용자가 관리 및 분석이 용이하도록 데이터베이스 및 유전체 서열분석 서비스 시스템을 구현하였다. 본 논문에서는 G-BLAST시스템의 성능확인을 위하여 병렬컴퓨팅 성능테스트 기법을 도입하여 구현된 시스템을 기존 BLAST와 속도 및 효율부분에서 비교하여 성능개선을 확인하였으며 서열결과 분석에 필요한 자료를 사용자관점에서 제공해주고 있다.

• Genomics & Informatics
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• 제20권3호
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• pp.36.1-36.6
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• 2022

BLAST, a basic bioinformatics tool for searching local sequence similarity, has been one of the most widely used bioinformatics programs since its introduction in 1990. Users generally use the web-based NCBI-BLAST program for BLAST analysis. However, users with large sequence data are often faced with a problem of upload size limitation while using the web-based BLAST program. This proves inconvenient as scientists often want to run BLAST on their own data, such as transcriptome or whole genome sequences. To overcome this issue, we developed NBLAST, a graphical user interface-based BLAST program that employs a two-way system, allowing the use of input sequences either as "query" or "target" in the BLAST analysis. NBLAST is also equipped with a dot plot viewer, thus allowing researchers to create custom database for BLAST and run a dot plot similarity analysis within a single program. It is available to access to the NBLAST with http://nbitglobal.com/nblast.

• Genomics & Informatics
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• 제4권4호
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• pp.173-181
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• 2006

Pattern finding is one of the important tasks in a protein or DNA sequence analysis. Alignment is the widely used technique for finding patterns in sequence analysis. BLAST (Basic Local Alignment Search Tool) is one of the most popularly used tools in bio-informatics to explore available DNA or protein sequence databases. BLAST may generate a huge output for a large sequence data that contains various sequence patterns. However, BLAST does not provide a tool to summarize and analyze the patterns or matched alignments in the BLAST output file. BLAST lacks of general and robust parsing tools to extract the essential information out from its output. This paper presents a pattern summary system which is a powerful and comprehensive tool for discovering pattern structures in huge amount of sequence data in the BLAST. The pattern summary system can identify clusters of patterns, extract the cluster pattern sequences from the subject database of BLAST, and display the clusters graphically to show the distribution of clusters in the subject database.

• Earthquakes and Structures
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• 제15권2호
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• pp.155-164
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• 2018

Design of structures subjected to blast loads are usually carried out through nonlinear inelastic dynamic analysis followed by imposing acceptance criteria specified in design codes. In addition to comprehensive aspects of inelastic dynamic analyses, particularly in analysis and design of structures subjected to transient loads, they inherently suffer from convergence and computational cost problems. In this research, a strategy is proposed for design of steel moment resisting frames under far range blast loads. This strategy is inspired from performance based seismic design concepts, which is here developed to blast design. For this purpose, an algorithm is presented to calculate the capacity modification factors of frame members in order to simplify design of these structures subjected to blast loading. The present method provides a simplified design procedure in which the linear dynamic analysis is preformed, instead of the time-consuming nonlinear dynamic analysis. Nonlinear and linear analyses are accomplished in order to establish this design procedure, and consequently the final design procedure is proposed as a strategy requiring only linear structural analysis, while acceptance criteria of nonlinear analysis is implicitly satisfied.

• Computers and Concrete
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• 제6권4호
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• pp.305-318
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• 2009

Fiber Reinforced Polymer (FRP) is widely used for retrofitting concrete structures for various purposes. Especially, for the retrofitting of concrete structures subjected to blast loads, FRP is proven to be a very effective retrofitting material. However, a systematic design procedure to implement FRP for concrete structure retrofitting against blast loads does not exist currently. In addition, in case of concrete structures with inarticulate geometrical boundary conditions such as arch structures, an effective analysis technique is needed to obtain reliable results based on minimal analytical assumptions. Therefore, in this study, a systematic and efficient blast analysis procedure for FRP retrofitting design of concrete arch structure is suggested. The procedure is composed of three sequential parts of preliminary analysis, breach and debris analysis, and retrofit-material analysis. Based on the suggested procedure, blast analyses are carried out by using explicit code, LS-DYNA. The study results are discussed in detail.

• 복합신소재구조학회 논문집
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• 제3권4호
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• pp.10-16
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• 2012

This study presents the effectiveness of a composite structure at improving blast resistance. The proposed composite structure consists of carbon fiber reinforced polymer (CFRP) and steel layers. While CFRP layer is used for blast energy reflection due to its high strength, steel layer is used for blast energy absorption due to its high ductility. A dynamic model is used to simulate the elastoplastic behavior of the proposed composite structure subject to blast load. Considering the magnitude variations of a blast event, the probability of failure of each layer is evaluated using reliability analysis. By assigning design probability of failure of each layer in the composite structure, the thickness of layers is optimized. A case study for the design of CFRP-steel composite structure subjected to an uncertain blast event is also presented.

• 화약ㆍ발파
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• 제37권3호
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• pp.1-12
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• 2019

폭발 해석 모델의 해석 방법은 직접적 해석과 간접적 해석으로 구별되며, 간접적 해석으로는 반경험적 해석 방법과 수치 해석적 방법으로 나뉜다. 본 연구에서는 반경험적 모델 해석의 프로그램인 ELS 폭발 해석 프로그램의 적용성을 평가하기 위해, 단순 해석 모델을 선정하고 다양한 반경험적 해석 프로그램인 AT-Blast, RC-Blast와 Kinney와 Graham의 경험식을 이용하여 자유 공중 폭발과 지표면 폭발에서의 폭발 하중 특성을 검토하였다. 단순 해석 모델에 대해 환산거리와 입사각에 대한 폭발 압력을 해석한 결과, 자유 공중 폭발 해석에서 환산거리의 범위는 $0.3{\sim}0.461m/kg^{1/3}$이고, 지표면 폭발 해석에서 환산거리의 범위는 $0.378{\sim}0.581m/kg^{1/3}$ 일 때 적합한 해석을 수행할 수 있으며, 입사각의 경우에는 $45^{\circ}$ 이내에서 해석한 결과가 적합한 것으로 판단된다.

• Structural Engineering and Mechanics
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• 제32권2호
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• pp.337-350
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• 2009

Finite element simulations are increasingly used in structural analysis and design, especially in cases where complex structural and loading conditions are involved. Due to considerable progresses in computer technology as well as nonlinear finite-element analysis techniques in past years, it has become possible to pursue an accurate analysis of the complex blast-induced structural effects by means of numerical simulations. This paper aims to develop a better understanding of the behavior of steel-concrete composite beams (SCCB) under localized blast loading through a numerical parametric study. A finite element model is set up to simulate the blast-resistant features of SCCB using the transient dynamic analysis software LS-DYNA. It is demonstrated that there are three dominant failure modes for SCCB subjected to localized blast loading. The effect of loading position on the behavior of SCCB is also investigated. Finally, a simplified model is proposed for assessing the overall response of SCCB subjected to localized blast loading.

• 한국기계가공학회지
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• 제11권3호
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• pp.130-137
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• 2012

Blast walls are integral structures at the typical offshore topside module to provide safety barriers for personnel and critical equipment against any blast loading and hydrocarbon explosions. The blast wall structures are usually configured with stainless steel. It can be referred as the good mechanical properties of the stainless steel against blast load, which features the characteristics of significant energy absorption and ductility. In this study, the proposed designs of corrugated panel are examined in order to determine the best design which satisfies the design criteria. The criteria on maximum deflection and stress are used to decide the best design. The effect of inclined angle of profile on deformation characteristics of blast wall is also performed. The numerical study was performed by using NX Nastran 7.5.

• Structural Engineering and Mechanics
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• 제46권5호
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• pp.595-613
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• 2013

A new effective model for calculation of the equivalent uniform blast load for non-uniform blast load such as close-in explosion of a one-way square and rectangle reinforced concrete slab is proposed in this paper. The model is then validated using single degree of freedom (SDOF) system with the experiments and blast tests for square slabs and rectangle slabs. Test results showed that the model is accurate in predicting the damage level on the tested RC slabs under the given explosive charge weight and stand-off distance especially for close-in blast load. The results are also compared with those obtained by conventional SDOF analysis and finite element (FE) analysis using solid elements. It is shown that the new model is more accurate than the conventional SDOF analysis and is running faster than the FE analysis.