• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2003년도 춘계학술발표논문집
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• pp.219-221
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• 2003

This system is Emergency patient medical examination and treatment way through biosignal transmission to use PDA. Store measured biosignal that is stored to file to database by Application, This system helps doctor's treatment that transmit patient's biosignal data and patient's symptoms use wireless internet. ThenOffer more than safer medical treatment environment to a doctor and patient

• 한국군사과학기술학회지
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• 제16권6호
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• pp.841-846
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• 2013

Recently, personal health monitoring system using intelligent biosensors and equipments has been realized. This system can be adopted for soldier's biosignal monitoring system. In this paper, we propose a soldier biosignal monitoring system using personal biosensors, such as the ECG sensors and accelerometer.

• 대한인간공학회지
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• 제29권1호
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• pp.47-53
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• 2010

An analysis of biosignal and performance data collected during driving has increasingly employed in research to explore a human-vehicle interface design for better safety and comfort. The present study developed a protocol and a system to effectively analyze biosignal and driving performance measurements in various driving conditions. Electrocardiogram (ECG), respiration rate (RR), and skin conductance level (SCL) were selected for biosignal analysis in the study. A data processing and analysis protocol was established based on a comprehensive review of related literature. Then, the established analysis protocol was implemented to a computerized system so that immense data of biosignal and driving performance can be analyzed with ease, efficiency, and effectiveness for an individual and/or a group of individuals of interest. The developed analysis system would be of use to examine the effects of driving conditions to cognitive workload and driving performance.

• 대한의용생체공학회:의공학회지
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• 제29권2호
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• pp.164-171
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• 2008

Recently, many of hospitals have hurried to computerize the resulting data from medical devices, in order to introduce Electric Medical Record(EMR). In terms of the linkage between medical devices and hospital information systems, however, many difficulties have arisen due to some reasons such as the variety of prescription input, the format difference of the resulting data sheet, and the interface difference between medical devices from different companies. To solve these problems, many researches on standardization of the resulting data of medical devices have been performed. In this study, the linkage between hospital information systems and resulting datum in Electrocardiogram(ECG) generating biosignal waveform was tested by applying Medical waveform Format Encoding Rules(MFER) Version 1.02, which has more advantages than existing global standard. MFER viewer, in addition, was made to display the resulting data on a screen. The MFER viewer was tested and compared to the existing Scalable Vector Graphics (SVG) Viewer. The results showed that this method is more effective in the interface the data storage and application, because of simplicity and easiness in data applications. And the results show that the MFER is convenience and effective for physician. It is considered that the role of MFER as the interface in biosignal waveform including Electrocardiogram medical devices would expand in the near future.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권1호
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• pp.1-15
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• 2019

Internet of Things (IoT) is commonly referred to as a future internet technology to provide advanced services by interconnecting physical and virtual things, collecting and using many data from them. The IoT platform is a server platform with a common architecture to collect and share the data independent of the IoT devices and services. Recently, oneM2M, the global standards initiative for Machine-to-Machine (M2M) communications and the IoT announced the availability of oneM2M Release 2 specifications. Accordingly, this paper presents a new oneM2M-compliant IoT platform called Mobius 2.0 and proposes its application to collect the biosignal data from wearable IoT devices for emotion recognition. Experimental results show that we can collect various biosignal data seamlessly and extract meaningful features from the biosignal data to recognize two emotions of joy and sadness.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 1998년도 춘계학술발표 논문집
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• pp.171-175
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• 1998

This work presents an estimation for stress status using biosignal and fuzzy theory. Stress is estimated by 'coin-build' experiment with two type, relax and stress status. The estimator uses five biosignals, fuzzy logic to combine these signals and physiological knowledge. The system was tested in 10 records of healthy indivisuals and acheived a template of a stress progress. This work presents an estimation for stress status using biosignal and fuzzy theory. Stress is estimated by 'coin-build' experiment with two type, relax and stress status. The estimator uses five biosignals, fuzzy logic to combine these signals and physiological knowledge. The system was tested in 10 records of healthy indivisuals and acheived a template of a stress progress.

• 한국위성정보통신학회논문지
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• 제9권2호
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• pp.80-84
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• 2014

유헬스는 정보통신기술과 생체의료기술을 융합하여 사용자에게 시간 및 공간적 제약이 없이 건강관리 및 의료 서비스를 제공하는 기술이다. 의사가 사용자의 건강상태를 원격으로 진단하기 위해서는 유헬스 기기의 생체신호 측정 기술과 측정된 생체 신호를 전송하는 통신 기술이 중요하다. 본 논문에서는 심전도측정센서, 영상모듈, GPS모듈, 통신모듈 및 MCU(Micro Controller Unit)를 이용하여 사람의 생체신호 중 심전도신호를 측정하여 영상 및 사용자의 위치정보를 무선으로 전송하는 생체신호 모니터링 시스템을 구현하는 과정을 소개한다.

• Journal of Microbiology and Biotechnology
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• 제28권3호
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• pp.439-447
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• 2018

The aromatic compound p-hydroxybenzoate (PHBA) is an important material with multiple applications, including as a building block of liquid crystal polymers in chemical industries. The cytochrome P450 (CYP) enzymes are beneficial monooxygenases for the synthesis of chemicals, and CYP53A15 from fungus Cochliobolus lunatus is capable of executing the hydroxylation from benzoate to PHBA. Here, we constructed a system for the bioconversion of benzoate to PHBA in Escherichia coli cells coexpressing CYP53A15 and human NADPH-P450 oxidoreductase (CPR) genes as a redox partner. For suitable coexpression of CYP53A15 and CPR, we originally constructed five plasmids in which we replaced the N-terminal transmembrane region of CYP53A15 with a portion of the N-terminus of various mammalian P450s. PHBA productivity was the greatest when CYP53A15 expression was induced at $20^{\circ}C$ in $2{\times}YT$ medium in host E. coli strain ${\Delta}gcvR$ transformed with an N-terminal transmembrane region of rabbit CYP2C3. By optimizing each reaction condition (reaction temperature, substrate concentration, reaction time, and E. coli cell concentration), we achieved 90% whole-cell conversion of benzoate. Our data demonstrate that the described novel E. coli bioconversion system is a more efficient tool for PHBA production from benzoate than the previously described yeast system.

• Journal of Microbiology and Biotechnology
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• 제30권8호
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• pp.1207-1213
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• 2020

Aflatoxin B1 (AFB1) is a mycotoxin produced by Aspergillus flavus (A. flavus). AFB1 is reported to have high thermal stability and is not decomposed by heat treatment during food processing. Therefore, in this study, knowing that AFB1 is metabolized by cytochrome P450 (CYP), our aim was to develop a method to detoxify A. flavus-contaminated maize, under normal temperature and pressure, using Escherichia coli expressing human CYP3A4. First, the metabolic activity of AFB1 by recombinant human CYP3A4 was evaluated. As a result, we confirmed that recombinant human CYP3A4 metabolizes 98% of AFB1. Next, we found that aflatoxin Q1, a metabolite of AFB1 was no longer mutagenic. Furthermore, we revealed that about 50% of the AFB1 metabolic activity can be maintained for 3 months when E. coli expressing human CYP3A4 is freeze-dried in the presence of trehalose. Finally, we found that 80% of AFB1 in A. flavus-contaminated maize was metabolized by E. coli expressing human CYP3A4 in the presence of surfactant triton X-405 at a final concentration of 10% (v/v). From these results, we conclude that AFB1 in A. flavus-contaminated maize can be detoxified under normal temperature and pressure by using E. coli expressing human CYP3A4.

• 한국컴퓨터정보학회논문지
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• 제15권12호
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• pp.19-26
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• 2010

본 논문에서는 일상생활 속에서 무자각적으로 생체신호를 측정하고 분석하여 감성을 평가할 수 있는 임베디드 시스템에 관하여 연구하였다. 지속적으로 변화하는 감성을 일관적이며 신뢰성이 높은 생리적인 방법으로 평가하기 위해 심전도(ECG:Electrocardiogram), 맥파(PPG:Photoplethysmography)의 두 가지 생체신호를 측정하고, 무선전송(Bluetooth) 장치를 이용하여 측정한 생체신호를 실시간으로 노트북PC로 전송하여 분석하였다. 생체신호의 분석방법은 고속 퓨리에 변환(FFT:Fast Fourier Transform)과 전력 스펙트럼 밀도(PSD:Power Spectrum Density)를 이용한 주파수 분석방법으로 두 생체신호의 특정 주파수 대역이 가지는 자율신경계의 활성도의 비율을 분석하여 비교 연구하였다. 또한 보다 빠르고 정확한 감성을 평가하기 위하여 분석 알고리즘의 연산을 최소화 하였으며 그래프를 이용한 분석결과의 시각화를 하였다. 본 논문에서는 무자각적인 생체 신호 측정 시스템을 이용하여 다양한 상황에서 생체신호를 측정하고, 개발한 분석 알고리즘으로 분석한 결과의 차이를 연구하여 정확도 및 신뢰도를 기준으로 감성을 평가하기 위한 분석 시스템을 평가하였다.