• Title/Summary/Keyword: Biomedical technology

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Performance Analysis of 403.5MHz CMOS Ring Oscillator Implemented for Biomedical Implantable Device (생체 이식형 장치를 위해 구현된 403.5MHz CMOS 링 발진기의 성능 분석)

  • Ferdousi Arifa;Choi Goangseog
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.19 no.2
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    • pp.11-25
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    • 2023
  • With the increasing advancement of VLSI technology, health care system is also developing to serve the humanity with better care. Therefore, biomedical implantable devices are one of the amazing important invention of scientist to collect data from the body cell for the diagnosis of diseases without any pain. This Biomedical implantable transceiver circuit has several important issues. Oscillator is one of them. For the design flexibility and complete transistor-based architecture ring oscillator is favorite to the oscillator circuit designer. This paper represents the design and analysis of the a 9-stage CMOS ring oscillator using cadence virtuoso tool in 180nm technology. It is also designed to generate the carrier signal of 403.5MHz frequency. Ring oscillator comprises of odd number of stages with a feedback circuit forming a closed loop. This circuit was designed with 9-stages of delay inverter and simulated for various parameters such as delay, phase noise or jitter and power consumption. The average power consumption for this oscillator is 9.32㎼ and average phase noise is only -86 dBc/Hz with the source voltage of 0.8827V.

Rapid Identification of Bioactive Compounds Reducing the Production of Amyloid β-Peptide (Aβ) from South African Plants Using an Automated HPLC/SPE/HPLC Coupling System

  • Kwon, Hak-Cheol;Cha, Jin-Wook;Park, Jin-Soo;Chun, Yoon-Sun;Moodley, Nivan;Maharaj, Vinesh J.;Youn, Sung-Hee;Chung, Sung-Kwon;Yang, Hyun-Ok
    • Biomolecules & Therapeutics
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    • v.19 no.1
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    • pp.90-96
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    • 2011
  • Automated HPLC/SPE/HPLC coupling experiments using the Sepbox system allowed the rapid identification of four bioactive principles reducing the production of amyloid $\beta$-peptide ($A{\beta}$) from two South African plants, Euclea crispa subsp. crispa and Crinum macowanii. The structures of biologically active compounds isolated from the methanol extract of Euclea crispa subsp. crispa were assigned as 3-oxo-oleanolic acid (1) and natalenone (2) based on their NMR and MS data, while lycorine (3) and hamayne (4) were isolated from the dichloromethane-methanol (1:1) extract of Crinum macowanii. These compounds were shown to inhibit the production of $A{\beta}$ from HeLa cells stably expressing Swedish mutant form of amyloid precursor protein (APPsw).

Development of a Finger Tactile Stimulator Based on E-Prime Software (E-Prime에 기반한 손가락 촉각 자극기의 개발)

  • Kim, Hyung-Sik;Min, Yoon-Ki;Kim, Bo-Seong;Min, Byung-Chan;Yang, Jae-Woong;Lee, Su-Jeong;Choi, Mi-Hyun;Yi, Jeong-Han;Tack, Gye-Rae;Lee, Bong-Soo;Jun, Jae-Hoon;Chung, Soon-Cheol
    • Science of Emotion and Sensibility
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    • v.13 no.4
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    • pp.703-710
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    • 2010
  • In this study, a tactile stimulator was developed to resolve some problems from the previous version of the system such as system configuration, inappropriate stimulation control and additional problems. The developed tactile stimulator consists of control unit, drive unit and vibrator unit. The control unit was controlled by E-Prime software to generate appropriate vibration pulses. The drive unit supplies enough energy to the vibrator to generate effective stimulation pulses. The vibrator unit consists of small coin type vibrator and velcro, and was made to be attached at the hand easily. The developed tactile stimulator was designed by small-size, light-weight, low-power, simple-fabrication, max 35 channels and little delay time from instruction signal of E-Prime software to vibrator. The duration and magnitude of stimulation was controlled by 10 grades and the problems concerning stimulation control were compensated by wideband frequency ranges. Additionally, the electrical safety was ensured by low voltage operation. Vibrator was made to be attached on finger as well as on any part of the subject. Since this tactile stimulator is developed based on E-Prime software which is widely used in cognitive science, it is believed that this stimulator be suitable for the wide application of cognitive science study.

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Biomechanical Evaluation for Washing Machine Design Suggested Newly for Prevention of Musculoskeletal Disorders (근골격계 질환 예방을 위하여 새로이 제시된 세탁기 디자인에 대한 생체역학적 평가)

  • Cho, Young-Kuen;Choi, Hue-Seok;Kim, Hyun-Dong;Choi, Hyun-Ho;Youn, Join-In;Kim, Young-Ho;Shin, Tae-Min;Kim, Han-Sung;Lim, Do-Hyung
    • Journal of the Ergonomics Society of Korea
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    • v.27 no.4
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    • pp.27-35
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    • 2008
  • Recently, many studies have reported the fact that an excessively accumulated psychological and physical burden induced from physical labor conducted routinely in home and industry can be one of main reasons of musculoskeletal disorders in the working population. This fact makes increase interests in studies to reduce a risk of musculoskeletal disorders through grafting ergonomic considerations on working environment. However, there are currently limited methodologies in quantitative evaluations of new ergonomic suggestions to reduce a risk of musculoskeletal disorders. The current study is therefore performed to evaluate quantitatively effects of a design of washing machine as a new ergonomic suggestion onto prevention of musculoskeletal disorders, through application of a biomechanical evaluation methodology. For this, three-dimensional motion analysis by using musculoskeletal models with Rapid Entire Body Assessment (REBA), which has been generally used for a simple evaluation of a degree of harmfulness of the human body at specific working postures to be considered, was performed. The results of REBA did not give us enough information and their results were somewhat simple and inaccurate, but the results of the three-dimensional motion analysis give us enough information such as alteration of main muscle forces and joint moments required during washing work. All results showed that the main muscle strengths and joint moments were decreased effectively for reduction of a risk of musculoskeletal disorders during the washing work with newly designed washing machine evaluated in the current study, compared with those generated during the washing work with general washing machine. From these results, it can be concluded that a risk of the musculoskeletal disorders, which may be induced by a repetitive washing work, may be reduced through using the washing machine designed ergonomically and newly. Also, it is thought that if our ergonomic design can be applied for improvement of working environment in lifting and laying works conducted repeatedly for a treatment work of goods, which have a strong resemblance to the behaviors generated frequently during the washing work, a possibility of occurrence of the musculoskeletal disorders by the lifting and laying works may be reduced highly.

A Study on the Validity of Changing the Job Title of Medical Technologist (임상병리사 명칭 변경을 위한 타당성 연구)

  • Koo, Bon-Kyeong;Kim, Won Shik;Park, Sun Gu;Park, Jong O;Yoon, Seong Min
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.1
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    • pp.105-121
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    • 2021
  • To investigate and accommodate opinions on the revision of the official occupational title of the medical technologist, the Korean Association of Medical Technologists (KAMT) requested 22,638 people registered as its regular members to participate in an online survey and select their two preferred options from the alternative job titles presented. Survey responses were collected from 3,999 people (17.66%). To examine job title preferences among the KAMT members, each respondent was asked to choose two terms from the choice set. As a result, 6,958 responses were obtained, and out of the total responses, 5,555 (79.83%) indicated a choice for a job title that included the word 'analyst' as the preferred alternative. The survey results showed that "Diagnostic Laboratory Analyst" was the most preferred alternative selected by the largest proportion of respondents (2,417 responses, 34.73%), followed by "Clinical Laboratory Analyst" (1,710 responses, 24.57%), "Biomedical Pathology Technologist" (758 responses, 10.89%), "Biomedical Analyst" (730 responses, 10.49%), "Biomedical Laboratory Analyst" (730 responses, 10.03%), and "Clinical Laboratory Scientist" (646 responses, 9.26%). Therefore, based on the responses of the surveyed members, results of consultation and literature review, the Standard Classification of Occupations (SCO), and the current status of the job titles used in major countries, it is suggested that the occupational title of medical technologists should be changed by adopting "Diagnostic Laboratory Analyst", "Biomedical Laboratory Analyst", or "Biomedical Analyst" as their new official job title.

Effect of good death cognition, self esteem, attitude toward withdrawal of life-sustaining treatment on the consciousness of biomedical ethics of nursing students (간호대학생의 좋은 죽음 인식, 자아존중감, 연명치료 중단에 대한 태도가 생명의료윤리 의식에 미치는 영향)

  • Park, Hyo Jin;Yang, Hyun Joo;Byun, Eun Kyung
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.3
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    • pp.71-78
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    • 2021
  • The purpose of this study was to investigate the effect of good death recognition, self-esteem, attitude toward withdrawal of life-sustaining treatmenton the consciousness of biomedical ethics in nursing students. Data were collected from 154 nursing students in B city and analyzed by t-test, ANOVA, Pearson correlation coefficient, and multiple regression using SPSS/WIN 22.0. The degree of consciousness of biomedical ethics in nursing students was 2.87±0.26. There were significant differences in consciousness of biomedical ethics with respect to religion(t=-2.90, p=.004). There was positive correlation between consciousness of biomedical ethics and good death recognition(r=.27, p=.001), self-esteem(r=.36, p<.001), negative correlation between consciousness of biomedical ethics and attitude toward withdrawal of life-sustaining treatment(r=-.29, p<.001). The factors affecting consciousness of biomedical ethics of the study subjects were good death recognition(β=.26, p<.001), self-esteem(β=.29, p<.001), attitude toward withdrawal of life-sustaining treatment(β=-.30, p<.001), religion(β=-.20, p=.004), with an explanatory power of 28.7%. Through this research requires the fellow study to determine the factors affecting consciousness of biomedical ethics of nursing students.

A Study on the Blink Pattern Extraction of a Driver in Drowsy State (졸음감지를 위한 깜박임 패턴 검출에 관한 연구)

  • Kim, B.J.;Park, S.S.;Oh, S.G.;Kim, N.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.322-325
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    • 1997
  • In this study, we propose a non-invasive method to detect the drowsiness of a driver. The computer vision technology was used to extract an eye, track eyelids and measure the parameters related to the blink. We examined the blink patterns of a driver in drowsy state. For the evaluation of our image processing algorithm, the blink patterns were compared with the measured EOG signals. The result showed that our algorithm might be available in detection of drowsiness.

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