• Proceedings of the KOSOMBE Conference
• /
• v.1997 no.05
• /
• pp.84-87
• /
• 1997

In this study, for the coding of stereoscopic video sequence, two approaches are presented based on simulcast mathod and sidefield image format. The field sequential method for stereoscopic visualization have been specified. Also, camera parameter and shooting conditions for each test sequence are studied. Coding method based on sidefield format structure revealed better performance over simulcast in PSNR.

• KOGO NEWS
• /
• v.5 no.4
• /
• pp.9-16
• /
• 2005

Bioinformatics is a rapidly emerging field of biomedical research. A flood of large-scale genomic expression data transforms the challenges m biomedical research into ones in bioinformatics. Clinical informatics has long developed technologies to imp개ve biomedical research by integrating experimental and clinical information systems. Biomedical informatics, powered by high throughput techniques, genomic-scale databases and advanced clinical information system, is likely to transform our biomedical understanding forever much the same way that biochemistry did to biology a generation ago. The emergence of healthcare and biomedical informatics revolutionizing both bioinformatics and clinical informatics will eventually change the current practice of medicine, including diagnostics, therapeutics and prognostics.

• Journal of Biomedical Engineering Research
• /
• v.42 no.3
• /
• pp.94-99
• /
• 2021

Atopic dermatitis (AD), a chronic inflammatory skin disease, is characterized by itchy and age-dependent lesions. Previous studies have shown that pulsed electromagnetic field (PEMF) significantly improved chronic ulcers and ununited fractures, providing an evidence for the application of PEMF in resolving inflammation caused by AD. This study investigated the anti-inflammatory effect of PEMF on DNCB-induced AD in animal models. Five male hairless mice (6 weeks old) per group were assigned to a normal group, a sham group, and two PEMF groups (15Hz, 75Hz). Mice were treated with 2,4-Dinitrochlorobenzene (DNCB) to induce uniform AD among all groups excluding a normal group. To examine the inflammatory progress and the improvement of AD after the PEMF stimulation, images are taken with various cameras for non-invasive evaluation and the results are expressed using principal component analysis (PCA) for visualization. The results of this study demonstrated that PEMF effectively improved skin lesions without the use of drugs.

• BMB Reports
• /
• v.55 no.3
• /
• pp.148-153
• /
• 2022

Etoposide is a chemotherapeutic medication used to treat various types of cancer, including breast cancer. It is established that pulsed electromagnetic field (PEMF) therapy can enhance the effects of anti-cancer chemotherapeutic agents. In this study, we investigated whether PEMFs influence the anti-cancer effects of etoposide in MCF-7 cells and determined the signal pathways affected by PEMFs. We observed that co-treatment with etoposide and PEMFs led to a decrease in viable cells compared with cells solely treated with etoposide. PEMFs elevated the etoposide-induced PARP cleavage and caspase-7/9 activation and enhanced the etoposide-induced down-regulation of survivin and up-regulation of Bax. PEMF also increased the etoposide-induced activation of DNA damage-related molecules. In addition, the reactive oxygen species (ROS) level was slightly elevated during etoposide treatment and significantly increased during co-treatment with etoposide and PEMF. Moreover, treatment with ROS scavenger restored the PEMF-induced decrease in cell viability in etoposide-treated MCF-7 cells. These results combined indicate that PEMFs enhance etoposide-induced cell death by increasing ROS induction-DNA damage-caspase-dependent apoptosis.

• Journal of Electrical Engineering and Technology
• /
• v.10 no.5
• /
• pp.2155-2161
• /
• 2015

This study suggests an optical method to measure cardinal of gait (step width, step length, and stride length) with position sensitive detector (PSD). The effect of reflector’s shape (flat and cylinder) on the PSD output voltage was examined for the application of the suggested system to real situations with a curved shape reflector (e.g. shoes). Various mathematical models were evaluated to find the optimal equation for the distance measurement. Considering the effect of shape on detected signal, the inverse polynomial model was developed. The suggested method is simple to operate, low in cost, small in size, and can evaluate gait parameters in real time. This method is expected to be useful in the field of rehabilitation and sport science

• Journal of Sensor Science and Technology
• /
• v.16 no.1
• /
• pp.33-38
• /
• 2007

In this study, one-dimensional fiber-optic radiation sensor with an organic scintillator tip is fabricated to measure high energy X-ray beam profile of CLINAC. According to the energy and field size of X-ray, scintillating light signal from one-dimensional fiber-optic sensor is measured using a photodiode-amplifier system. This sensor has many advantages such as high resolution, real-time measurement and ease calibration over conventional ion chamber and film.

• Biomedical Science Letters
• /
• v.29 no.2
• /
• pp.53-57
• /
• 2023

The main objective of pathologists is to achieve accurate lesion diagnoses, which has become increasingly challenging due to the growing number of pathological slides that need to be examined. However, using digital technology has made it easier to complete this task compared to older methods. Digital pathology is a specialized field that manages data from digitized specimen slides, utilizing image processing technology to automate and improve analysis. It aims to enhance the precision, reproducibility, and standardization of pathology-based researches, preclinical, and clinical trials through the sophisticated techniques it employs. The advent of whole slide imaging (WSI) technology is revolutionizing the pathology field by replacing glass slides as the primary method of pathology evaluation. Image processing technology that utilizes WSI is being implemented to automate and enhance analysis. Artificial intelligence (AI) algorithms are being developed to assist pathologic diagnosis and detection and segmentation of specific objects. Application of AI-based digital pathology in biomedical researches is classified into four areas: diagnosis and rapid peer review, quantification, prognosis prediction, and education. AI-based digital pathology can result in a higher accuracy rate for lesion diagnosis than using either a pathologist or AI alone. Combining AI with pathologists can enhance and standardize pathology-based investigations, reducing the time and cost required for pathologists to screen tissue slides for abnormalities. And AI-based digital pathology can identify and quantify structures in tissues. Lastly, it can help predict and monitor disease progression and response to therapy, contributing to personalized medicine.

• Proceedings of the Korean Society of Medical Physics Conference
• /
• 1999.11a
• /
• pp.414-415
• /
• 1999

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.64 no.5
• /
• pp.792-798
• /
• 2015

Joint angle generally can be measured to check the recovery process in rehabilitation field. This paper suggests to measure joint angle with Infrared sensor based on triangulation principle. We performed various experiments to find the optimal condition of the sensor’s attached distance, height, and angle. The results were compared with commercial goniometer for accuracy. The proposed infrared joint angle sensor can be effectively used in rehabilitation and sport science fields.

• Investigative Magnetic Resonance Imaging
• /
• v.24 no.2
• /
• pp.67-75
• /
• 2020

When a patient takes an MRI scan, the patient has a risk of unexpected injuries due to the intensive electromagnetic (EM) field. Among the injuries, the tissue heating by the time-varying EM field is one of the main issues. Since an implanted artificial structure with a conductive material aggravates the heating effect, lots of studies have been conducted to investigate the effect around the implants. In this review article, a mechanism of RF heating around the implants and related studies are comprehensively investigated.