• 제목/요약/키워드: Biomedical engineering

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Polymer Nanofibers for Biomedical Engineering

  • Shin, Min-Kyoon;Kim, Seon-Jeong;Kim, In-Young;Kim, Sun-I.
    • 대한의용생체공학회:의공학회지
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    • 제29권3호
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    • pp.173-178
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    • 2008
  • Recent advancements in the electrospinning method enable the production of ultrafine solid and continuous fibers with diameters ranging from a few nanometers to a few hundred nanometers with controlled surface and morphological features. A wide range of biopolymers can be electrospun into mats with a specific fiber arrangement and structural integrity. These features of nanofiber mats are morphologically similar to the extracellular matrix of natural tissues, which are characterized by a wide pore diameter distribution, a high porosity, effective mechanical properties, and specific biochemical properties. This has resulted in various kinds of applications for polymer nanofibers in the field of biomedicine and biotechnology. The current emphasis of research is on exploiting these properties and focusing on determining the appropriate conditions for electrospinning various biopolymers for biomedical applications, including scaffolds used in tissue engineering, wound dressing, drug delivery, artificial organs, and vascular grafts, and for protective shields in specialty fabrics. This paper reviews the research on biomedical applications of electrospun nanofibers.

감마선 분포 측정을 위한 섬광필름 기반의 감마 영상 검출기 제작 및 성능평가 (Fabrication and Performance Evaluation of a Scintillating Film-based Gamma Imaging Detector to Measure Gamma-ray Distribution)

  • 신상훈;유욱재;장경원;조승현;이봉수
    • 센서학회지
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    • 제24권3호
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    • pp.202-207
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    • 2015
  • As a feasibility study on development of a gamma imaging probe, we developed a scintillating film-based gamma imaging detector that can obtain scintillation images with information of gamma-ray distribution. The scintillating film-based gamma imaging detector was composed of a sensing probe, an image intensifier, and a beam profiler. To detect and transmit scintillation image, the sensing probe was fabricated by coupling a scintillating film, a fiber-optic image conduit, and a fiber-optic taper, consecutively. First, the optical images of USAF 1951 resolution target were obtained and then, modulation transfer function values were calculated to test the image quality of the sensing probe. Second, we measured the scintillation images according to the activity of the 137Cs and the distance between the surface of 137Cs and the distal-end of sensing probe. Finally, the intensities of scintillating light as functions of the activity and the distance were evaluated from the region of interest in the scintillation image. From the results of this study, it is expected that a fiber-optic gamma imaging detector can be developed to detect gamma-rays emitted from radiopharmaceuticals during radioimmunoguided surgery.

요 스트립검사 자동화를 위한 동시 비교 스캔 기법 예비 연구 (Automation of urine dipstick test by simultaneous scanning : A pilot study)

  • 이상봉;최성수;이인광;한정수;김완석;김원재;차은종;김경아
    • 센서학회지
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    • 제19권3호
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    • pp.169-175
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    • 2010
  • Urinalysis is an important clinical test to diagnose urinary diseases, and dipstick method with visual inspection is widely applied in practice. Automated optical devices recently developed have disadvantages of long measurement time, big size and heavy weight, accuracy degradation with time, etc. The present study proposed a new computer scanning technique, in which the test strip and the standard chart were simultaneously scanned to remove any environmental artifacts, followed by automated differentiation with the minimum distance algorithm, leading to significant enhancement of accuracy. Experiments demonstrated an accuracy of 100 % in that all test results were identical with the human visual inspection. The present technique only uses a personal computer with scanner and shortens the test time to a great degree. The results are also stored and accumulated for later use which can be transmitted to remote locations through a network, thus could be easily integrated to any ubiquitous health care systems.

Co-registration of Human Brain MR and PET Images using the AC-PC Line

  • 백철화;유현선;김원기
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1996년도 추계학술대회
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    • pp.155-156
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    • 1996
  • The intercommissural(AC-PC) line is automatically detected for HR and PET images. With the detected AC-PC lines from MR and PET images, fully non-iterative automatic co- registration is accomplished. It provides a new automated method for image co-registration.

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Can We Estimate the LAP, RAP, PAP, AoP and CO from the Interventricular Pressure and Motor Current in a Moving- Actuator type Total Artificial Heart? Yes, We Can

  • 엄경식;안재목;박성근;조영호;최원우;최재순;김희찬;민병구
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1997년도 춘계학술대회
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    • pp.59-63
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    • 1997
  • It is needless to say that the hemodynamic variables estimation is a very important study for the artificial heart. Even though its importance there have not been satisfactory results which can be applied to the real-world situations. This paper surveys and recommends how to cope with the problem of hemodynamic variable estimation for the moving-actuator type total artificial heart (MA-TAH).

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감음성(感音性) 난청인의 언어청력 향상에 관한 연구 (An Improvement of Speech Hearing Ability for sensorineural impaired listners)

  • 이상민;우효창;김동욱;송철규;이영묵;김원기
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1996년도 춘계학술대회
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    • pp.240-242
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    • 1996
  • In this paper, we proposed a method of a hearing aid suitable for the sensorineural hearing impaired. Generally as the sensorineural hearing impaired have narrow audible ranges between threshold and discomfortable level, the speech spectrum may easily go beyond their audible range. Therefore speech spectrum must be optimally amplified and compressed into the impaired's audible range. The level and frequency of input speech signal are varied continuously. So we have to make compensation input signal for frequency-gain loss of the impaired, specially in the frequency band which includes much information. The input sigaal is divided into short time block and spectrum within the block is calculated. The frequency-gain characteristic is determined using the calculated spectrum. The number of frequency band and the target gain which will be added input signal are estimated. The input signal within the block is processed by a single digital filter with the calculated frequency-gain characteristics. From the results of monosyllabic speech tests to evaluate the performance of the proposed algorithm, the scores of test were improved.

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