• The Journal of Korean Physical Therapy
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• 제8권1호
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• pp.49-64
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• 1996

The technology of gait analysis is moving rapidly. Human gait is very complex, and a through understanding of it demands with the basic principles of biomechanics and the technology used to measure gait. Some professionals reluctance to use gait analysis may be due to the amount of time and effort necessary to accomplish this and the necessity for teamwork among the disciplines involved. Any form of observational gait analysis has limited precision and is more descriptive than quantative. The techniques of 3-D kinetic and kinematic analysis can provide a detailed biomechanical description of normal and pathological gait. This article review gait characteristics and procedures that are available for gait analysis. We are certain that, given the steady advance of technology and our continued efforts to document the benefits of that technology. gait analysis will soon be a routine part of the evaluation of both the elite athlete and the physically impaired adult or child.

• BMB Reports
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• 제39권2호
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• pp.132-139
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• 2006

Vascular endothelial cadherin (VE-cadherin), which belongs to the classical cadherin family, is localized at adherens junctions exclusively in vascular endothelial cells. Biochemical and biomechanical cues regulate the VE-cadherin adhesive potential by triggering the intracellular signals. VE-cadherin-mediated cell adhesion is required for cell survival and endothelial cell deadhesion is required for vascular development. It is therefore crucial to understand how VE-cadherin-based cell adhesion is controlled. This review summarizes the inter-endothelial cell adhesions and introduces our recent advance in Rap1-regulated VE-cadherin adhesion. A further analysis of the VE-cadherin recycling system will aid the understanding of cell adhesion/deadhesion mechanisms mediated by VE-cadherin in response to extracellular stimuli during development and angiogenesis.

• PNF and Movement
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• 제5권1호
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• pp.37-47
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• 2007

Objective : A large proportion of stroke survivors have to deal with problems in gait. Proper evaluation of gait must be undertaken to understand the sensorimotor impairment underlying locomotor disorders post stroke. Methods : The characteristics of gait pattern with post stroke are reviewed in this paper. In particular, temporal distance parameters, kimematics, kinetics, as well as energy cost, EMG are focused. Results : The technology for gait analysis is moving rapidly. The techniques of 3D kinematic and kinetic analysis can provide a detailed biomechanical description of normal and pathological gait. This article reviews gait analysis method and characteristics of post stroke. Finally current method of gait analysis can provide further insight to understand paretic gait and therapeutic direction.

• Journal of Periodontal and Implant Science
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• 제46권3호
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• pp.176-196
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• 2016

Purpose: We sought to evaluate the effectiveness of bone substitutes in circumferential periimplant defects created in the rabbit tibia. Methods: Thirty rabbits received 45 implants in their left and right tibia. A circumferential bone defect (6.1 mm in diameter/4 mm depth) was created in each rabbit tibia using a trephine bur. A dental implant ($4.1mm{\times}8.5mm$) was installed after the creation of the defect, providing a 2-mm gap. The bone defect gaps between the implant and the bone were randomly filled according to the following groups: blood clot (CO), particulate Bio-Oss$^{(R)}$ (BI), and Bio-Oss$^{(R)}$ Collagen (BC). Ten animals were euthanized after periods of 15, 30, and 60 days. Biomechanical analysis by means of the removal torque of the implants, as well as histologic and immunohistochemical analyses for protein expression of osteocalcin (OC), Runx2, OPG, RANKL, and TRAP were evaluated. Results: For biomechanics, BC showed a better biological response ($61.00{\pm}15.28Ncm$) than CO ($31.60{\pm}14.38Ncm$) at 30 days. Immunohistochemical analysis showed significantly different OC expression in CO and BC at 15 days, and also between the CO and BI groups, and between the CO and BC groups at 60 days. After 15 days, Runx2 expression was significantly different in the BI group compared to the CO and BC groups. RANKL expression was significantly different in the BI and CO groups and between the BI and BC groups at 15 days, and also between the BI and CO groups at 60 days. OPG expression was significantly higher at 60 days postoperatively in the BI group than the CO group. Conclusions: Collectively, our data indicate that, compared to CO and BI, BC offered better bone healing, which was characterized by greater RUNX2, OC, and OPG immunolabeling, and required greater reversal torque for implant removal. Indeed, along with BI, BC presents promising biomechanical and biological properties supporting its possible use in osteoconductive grafts for filling peri-implant gaps.

• 대한의용생체공학회:의공학회지
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• 제36권6호
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• pp.276-282
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• 2015

Recently, during the multi-level fusion with pedicle screws, interspinous spacer are sometimes substituted for the most superior level of the fusion in an attempt to reduce the number of fusion level and likelihood of degeneration process at the adjacent level. In this study, a finite element (FE) study was performed to assess biomechanical efficacies of the interspinous spacer combined with posterior lumbar fusion with a previously-validated 3-dimensional FE model of the intact lumbar spine (L1-S1). The post-operative models were made by modifying the intact model to simulate the implantation of interspinous spacer and pedicle screws at the L3-4 and L4-5. Four different configurations of the post-op model were considered: (1) a normal spinal model; (2) Type 1, one-level fusion using posterior pedicle screws at the L4-5; (3) Type 2, two-level (L3-5) fusion; (4) Type 3, Type 1 plus Coflex$^{TM}$ at the L3-4. hybrid protocol (intact: 10 Nm) with a compressive follower load of 400N were used to flex, extend, axially rotate and laterally bend the FE model. As compared to the intact model, Type 2 showed the greatest increase in Range of motion (ROM) at the adjacent level (L2-3), followed Type 3, and Type 1 depending on the loading type. At L3-4, ROM of Type 2 was reduced by 34~56% regardless of loading mode, as compared to decrease of 55% in Type 3 only in extension. In case of normal bone strength model (Type 3_Normal), PVMS at the process and the pedicle remained less than 20% of their yield strengths regardless of loading, except in extension (about 35%). However, for the osteoporotic model (Type 3_Osteoporotic), it reached up to 56% in extension indicating increased susceptibility to fracture. This study suggested that substitution of the superior level fusion with the interspinous spacer in multi-level fusion may be able to offer similar biomechanical outcome and stability while reducing likelihood of adjacent level degeneration.

• 한국산학기술학회논문지
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• 제12권12호
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• pp.5766-5772
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• 2011

본 연구는 아킬레스 건염 환자들과 정상인들을 대상으로 보행 선형지표와 고관절, 슬관절, 그리고 족관절의 모멘트 변화를 조사하여 아킬레스 건염에 의한 보행의 역학적 변화를 구명하고 아킬레스 건염을 예방하기 위한 예측인자들을 찾고자 실시되었다. 연구의 대상자는 아킬레스 건염 환자 20명과 비슷한 신체조건을 가진 건강한 정상인 20명이며, 대상자가 맨발 상태에서 힘판의 중앙 부분을 밟고 지나가도록 13 m의 거리를 편안한 속도로 5회 왕복하도록 하였다. 또한 대상자가 보행하는 동안 3차원 동작분석 장비를 이용하여 고관절, 슬관절, 그리고 족관절 모멘트를 산출하였다. 수집된 자료들을 SPSS 12.0 소프트웨어를 사용하여 분석하였다. 연구의 결과 아킬레스 건염 환자들의 고관절은 입각기 초기에 신전 모멘트가 감소하였고, 중후반에는 굴곡 모멘트가 감소하였다. 또한 슬관절에서는 입각기 초기부터 지속적인 굴곡 모멘트의 감소가 나타났으며 후기에는 신전 모멘트의 감소를 보였다. 그리고 족관절은 입각기 중반에 저측굴곡 모멘트가 감소하였으며 말기에는 배측 굴곡 모멘트가 감소하였다. 정상인과 비교해 아킬레스 건염 환자들에게서 보행의 역학적인 변화가 두드러지게 나타났으며, 임상에서는 아킬레스 건염 환자의 보행에 대한 변화를 세밀하게 파악하여 치료적 접근을 시도해야 할 것으로 보인다. 그리고 앞으로의 연구에서는 아킬레스 건염 환자에게서 나타나는 역학적인 변화에 대한 조사가 더 이루어져야 할 것이다.

• 대한기계학회논문집A
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• 제31권11호
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• pp.1115-1123
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• 2007

The foot plays an important role in supporting the body and keeping body balance. An abnormal walking habit breaks the balance of the human body as well as the function of the foot. The foot orthotics which is designed to consider biomechanics effectively distributes the load of the human body on the sole of the foot. In this paper, gait analysis was performed for three male subjects wearing the orthotics. In this study, three male subjects were selected. The experimental apparatus consists of a plantar pressure analysis system and digital EMG system. The gait characteristics are simulated by ADAMS/LifeMOD. The COP (Center of Pressure), EMG and ground reaction force were investigated. As a result of gait analysis, the path of COP was improved and muscle activities were decreased with orthotics on the abnormal walking subjects.

• 한국융합학회논문지
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• 제9권8호
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• pp.301-309
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• 2018

본 연구의 목적은 여성선수의 신경인지능력이 양발 착지 시 비접촉성 전방십자인대 손상의 위험요인과 어떠한 관계가 있는지 규명하는 것이다. 여성선수 32명을 대상으로 신경인지검사와 양발 착지에 대한 동작분석을 실시하였다. 전산화된 신경인지 검사의 원점수와 동작분석을 통해 산출된 3차원 관절각, 모멘트, 파워, 수직지면반력, 부하율, 지지시간의 상관관계 분석을 위해 피어슨의 정률상관분석을 실시하였다. 연구결과 신경인지 점수가 높을수록 착지 시 자세유지를 위한 전략을 사용하는 것이 관찰되었다. 따라서 신경인지 검사는 잠재적인 전방십자인대 손상의 위험인자를 검출하기 위한 스크리닝 방법으로 사용 될 수 있을 것으로 생각된다.

• 대한의용생체공학회:의공학회지
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• 제29권2호
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• pp.139-145
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• 2008

Many recent studies suggest that the posterior dynamic stabilization(PDS) can be a more physiologically-relevant alternative to the rigid fixation for the patients suffering from low back pain. However, its biomechanical effects or clinically proven efficacies still remain unknown. In this study, we evaluated kinematic behaviors of the lower lumbar spine with the PDS system and then compared to those of the rigid fixation system using finite element (FE) analysis. A validated FE model of intact lumbar spine(L2-L5) was developed. The implanted model was then constructed after modification from the intact to simulate two kinds of pedicle screw systems (PDS and the rigid fixation). Hybrid protocol was used to flex, extend, laterally bend and axially rotate the FE model. Results showed that the PDS systems are more flexible than rigid fixation systems, yet not flexible enough to preserve motion. PDS system allowed $16.2{\sim}42.2%$ more intersegmental rotation than the rigid fixation at the implanted level. One the other hand, at the adjacent level it allowed more range of motion ($2.0%{\sim}8.3%$) than the rigid fixation. The center of rotation of the PDS model remained closer to that of the intact spine. These results suggest that the PDS system could be able to prevent excessive motion at the adjacent levels and restore the spinal kinematics.

• Structural Engineering and Mechanics
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• 제74권4호
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• pp.567-576
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• 2020

Considerable controversy surrounds the choice of the best abutment type for implant prosthetics. The two most common structures are hex and non-hex abutments. The non-hex abutment typically furnishes a larger contact area between itself and the implant than that provided by a hex structure. However, when a hex abutment is loaded, the position of its contact area may be deeper than that of a non-hex abutment. Hence, the purpose of this study is to determine the different biomechanical behaviors of an internal bone-level implant based on the abutment type-hex or non-hex-and clinical crown length under static and cyclic loadings using finite element analysis (FEA). The hex structure was found to increase the implant and abutment stability more than the nonhex structure among several criteria. The use of the hex structure resulted in a smaller volume of bone tissues being at risk of hypertrophy and fatigue failure. It also reduced micromovement (separation) between the implant components, which is significantly related to the pumping effect and possible inflammation. Both static and fatigue analyses, used to examine short- and long-term stability, demonstrated the advantages of the hex abutment over the non-hex type for the stability of the implant components. Moreover, although its impact was not as significant as that of the abutment type, a large crown-implant ratio (CIR) increased bone strain and stress in the implant components, particularly under oblique loading.