• Journal of Applied Biological Chemistry
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• 제53권1호
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• pp.8-12
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• 2010

The antioxidant activity of hawthorn fruit (Crataegus pinnatifida Bunge var. typica Schneider) extracts was investigated by several in vitro antioxidants properties, including DPPH free radical scavenging activity, total phenolic and flavonoid contents, hydroxyl radical scavenging activity, reducing power activity, iron-chelating capacity and nitrite scavenging activity. Among the extracts in this study, the 70% EtOH extract showed higher antioxidant activity than the others. The $IC_{50}$ value of DPPH free radical scavenging activity was $99.26\;{\mu}g/mL$. Furthermore, the 70% EtOH extract also showed significantly high total phenolic and flavonoids contents and reducing power activity. However, the MeOH extract exhibited stronger effects on hydroxyl radical scavenging activity, iron-chelating capacity and nitrite scavenging activity. All the results implicated that, the hawthorn fruit may has the available potential to be utilize as a potential source of natural antioxidant.

• Applied Biological Chemistry
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• 제41권4호
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• pp.218-221
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• 1998

Various cinnamaldehyde derivatives were synthesized and their inhibition activity $(pI_{50})$ of farnesyl protein transferase (FPTase) was measured to examine the structure-activity relationships (SAR) on the basis that FPTase was inhibited by ortho-hydroxycinnamaldehyde derived from extracts of the bark of Cinnamomum cassia Blume. The ortho-substituents on the phenyl backbone of cinnamaldehyde showed higher activity than those with meta- and para-substituents, and the side chain required unsaturated aldehyde. In particular, 2-chlorocinnamaldehyde, 5 showed the highest inhibition activity on the FPTase among them and its inhibition activity $(pI_{50})$ value was 4.45.

• Journal of Microbiology and Biotechnology
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• 제11권6호
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• pp.928-933
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• 2001

Approximately 0.1 mg/ml of polyvinyl alcohol (PVA) was degraded by the growing cell, Brevibacillus laterospours, for 30 h, and 0.2 mg/ml of PVA was degraded by the cell-free extract that was isolated from Brevibacillus laterosporus. Approximately $0.29{\mu}g$/ml of acetic acid was produced from PVA by using the cell-free extract as a catalyst for 40 min. $V_{max}\;and\;K_m$ value of purified PAV-degradation enzyme was 3.75g/l and 2.75 g/l/min in reaction with EDTA and 3.99 g/l and 2.98 g/l/min in reaction without EDTA, respectively. Molecular weight of the purified enzyme determined by SDS-PAGE was 63,000 Da. Alcohol dehydrogenase and aldehyde dehydrogenase activities were qualitatively detected on a native acrylamide gel by an active staining method, indicating the existence of the metabolic pathway to use PVA as a substrate.

• Journal of Applied Biological Chemistry
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• 제56권2호
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• pp.101-107
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• 2013

Physicochemical properties of kochujang prepared with different concentration of turmeric were compared. The number of yeast and bacteria in the kochujang were low in the group with more than 1% of turmeric while the amylase and protease activity increased in the group with less than 1% of turmeric. The L- and b-values increased as the concentration of turmeric increased, however a-value decreased. The titratable acidity was low in the high percentage of turmeric added group. Oxidation-reduction potential increased in the later stage of fermentation with decrease in Aw. Reducing sugar and alcohol were high in than higher turmeric added group. Amino- and ammonia-type nitrogen were the highest in the 0.5% turmeric added group. The overall acceptability of kochujang was significantly more favorable (p<0.05) in the 0.25% turmeric added group than over 1% turmeric added one.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.453-456
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• 1997

In this paper, we present the developement of Biofeedback system. Biofeedback is a method for learned control of physiological response of the body. It can be used to control certain biological response that cause health problems. Over the past 2 decades, biofeedback has received much attention from medicine as a cure-all for a variety of disease. It has been heralded as a technique that can provide normalization of disturbed physiology without the need for drugs or surgery and their attendant negative side effects. Biofeedback system has been implemented by using PIC microprocessor. We have displayed 5-channel value on PC and managed patient information by using Delphi.

• 수산경영론집
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• 제43권3호
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• pp.23-30
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• 2012

This study aimed to analyze the economic feasibility of Mackerel offshore aquaculture production performance in Jeju region, Korea. Based on the collected biological, costs and market price data, farming revenue and expenses during the farming period were evaluated, and the net present value and the internal rate of return of a 10-year cash inflow and cash outflow were estimated to determine the economic feasibility of Mackerel offshore aquaculture production system. Model results indicated that the Mackerel offshore aquaculture production performance would have high profitability under the current production and market situation. This is because of the relatively high survival rate, relatively low feed conversion ratio and good market prices. However, sensitivity analyses of main important biological and economic variables showed that the economic viability of Mackerel offshore aquaculture production system would be highly vulnerable to production and market condition changes.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.319-323
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• 2005

This study is concerned with development of efficient culture methods for lactic acid fermentation of Lactobacillus sp. RKY2. The cell-recycle repeated batch fermentation using cheese whey and corn steep liquor as raw materials was tried in order to further enhance the productivity of lactic acid. In addition, fermentation efficiencies could be considerably enhanced by cell-recycle continuous culture. Through the cell-recycle repeated batch fermentation, lactic acid productivity was maximized to 6.34 $g/L{\cdot}h,$ which corresponded to 6.2 times higher value than that of the batch fermentation. During the cell-recycle continuous fermentation, the last dry cell weight at the end of fermentation could be increased to 25.3 g/L.

• Natural Product Sciences
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• 제26권2호
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• pp.118-131
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• 2020

Mushrooms are known for their various attributes in the fields of nutrition and therapeutics. With exceptional taste, aroma, and nutritional value, they are considered 'functional food'-improving health and providing nutritional benefits to the body. Mushrooms have also been widely applied therapeutically as they possess diverse bioactive compounds known as secondary metabolites. These secondary metabolites demonstrated diverse biological properties such as anticancer, anti-diabetic, immunomodulatory, antimicrobial, anti-inflammatory, antiviral, anti-allergic, and antioxidative activities. This review presents bioactive compounds from the field of mushroom metabolite research and discusses important findings regarding bioactive compounds identified during the last five years (2015 - 2019).

• 한국환경보건학회지
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• 제16권1호
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• pp.21-28
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• 1990

As a research for treatment of waste water by biological method, we investigated general characteristics of waste water and isolated some useful bacteria which effectively treated waste water. Compositions of waste water were analyzed to give COD 2060 ppm, PVA 560 ppm, T-N 50 ppm, T-P 3.3 ppm and PH 12. Also, we inverstigated optimum nutrients requirement and growth conditions by mixed culture as well as the effect of coagulants. The COD removal rate reached maximum state for 48 hrs culture at pH 7.0 and 30$^{\circ}$C. Alum as the coagulated was the most effective. The COD removal rate was also increased by supplementing 10 ppm phosphorous sources as additional nutrients. The COD of waste water was reduced to 10% of its initial value by the continuous culture. As a result of overall experiments the COD of effluents became about 100 ppm and final pH 7.

• 한국약용작물학회지
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• 제21권5호
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• pp.388-393
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• 2013

This study was conducted to select environmental friendly organic materials for controlling the ginseng alternaria blight and to evaluate their effects from 2011 to 2012. Alternaria blight is caused by Alternaria panax and is the most common ginseng disease in Korea. Environmental friendly organic materials were used to reduce amount of chemical fungicides and the number of spray for control of Ginseng Alternaria leaf blight. In 4 years of ginseng, control value of Alternaria leaf blight by single application of Defenoconazole WP was 82.3% and those of single application was 62.0~75.9%. Consequently, mixed or alternated application of eco-material products could be recommended as a control method to reduce the amount of fungicides.