• Applied Biological Chemistry
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• 제23권2호
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• pp.89-105
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• 1980

Soysauce was made in the salt concentrations of 22.0% and 28.5%, and the changing aspects in nucleotides and their related compounds, free amino acids, free sugars and non-volatile amines which are related to the taste components during the fermentation process with a view to examining the taste components in the ordinary Korean soysauce were studied. And then artificial soysauce was prepared by applying the values derived from the analysis and measurement, and its sensory evaluation was performed. As the result of the sensory evaluation of artificial soysauce prepared according to the value of components analyzed from soysauce which had been fermented for fourty days in the salt concentration of 22.0%, it has been found that artificial soysauce was similar in taste to ordinary Korean soysauce. So, the following facts have been found: glutamic acid and aspartic acid have MSG-like taste, and IMP has a synergistic effect with these acids, which play great roles in ordinary Korean soysauce; both free sugars such as galactose and amino acids such as glycine, alanine and lysine have sweet taste; both amines such as tyramine and histamine, and amino acids such as valine, leucine, isoleucine, and phenylalanine have bitter taste; these components, combined with saline taste of salt and sour taste of organic acids, are assumed to form the unique taste in the ordinary Korean soysauce.

• 한국물환경학회지
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• 제31권3호
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• pp.253-261
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• 2015

The purpose of this study is the efficient biological treatment of highly concentrated nitrate nitrogen by calcium ion control present within the pickling wastewater. In laboratory scale's experiments research was performed using a sequencing batch reactor and the evaluation of denitrification reaction in accordance with the injection condition of calcium ions, the surface properties of microorganisms, and the evaluation of sludge precipitability were performed. Results of the study showed that the denitrification reaction was delayed when injecting more than 600 mg/L of the calcium ion within the denitrification process. In addition, we observed the absorption form of calcium ions absorbed on the surface of microorganisms following an increase in the calcium ion dose. It was found that as the calcium ion dose increased the sludge precipitability also increased continuously and it is judged that a smooth denitrification induction is possible when treating the nitrate nitrogen by the calcium ion control of pickling waste water and the shortening of precipitation time enables a liquid operation to increase the reaction time.

• 한국산업보건학회지
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• 제26권4호
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• pp.396-403
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• 2016

Objectives: The study is to evaluate biological monitoring and risk assessment for epichlorohydrin-bisphenol A resin exposed from waterproofing or finishing work in the apartment building construction. Methods: Subjected workers were working on spray-painting and waterproofing work for 8 hours per day every 20 days. The urine samples were collected at the end of 20 days working period. For urinary bisphenol A as metabolite from epichlorohydrin-bisphenol A exposure, urine samples were analyzed with liquid chromatography mass-mass spectrometry(HPLC-MS/MS). Results: Geometric means of urinary bisphenol A(BPA) with no hydrolysis and with enzymic hydrolysis(BPA-EH) in the workers were $1.10{\mu}g/L$ and $2.90{\mu}g/L$. BPA-EH was 4 times higher than that of control group. The factors for working period and ages did not affect the variation of BPA and BPA-EH. The levels for BPA and BPA-EH were not higher than 95th percentile for exposure on human-life environment. Conclusions: The BPA and BPA-EH were therefore effective biological markers for epichlorohydrin-bisphenol A exposure workers, but not seem to hazardous exposure level. Waterproofing work in construction workshop is required to measuring work environment and health care management for the workers.

• 한국환경농학회지
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• 제27권4호
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• pp.395-405
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• 2008

The objective of this study was to set priority for future core technologies in agricultural and environmental science using analytic hierarchy process(AHP). Forty-six technologies were derived by specialist meetings. Evaluation criteria, for setting the priority were decided as 'technology', 'marketability', and 'public'. Eighteen specialists in agricultural and environmental science answered to the questionnaire for AHP. As the results, 'technology' was decided as the most important evaluation criterion. The 'Feasibility' in 'technology' criterion, 'Market Growth' in 'marketability' criterion, and 'Impact to other industry' in 'public' criterion were decided as sub-criteria in each criterion. The most important technology was 'Risk assessment of toxic heavy metals and establishment of accreditation criteria for environmentally friendly agricultural products.

• Journal of Applied Biological Chemistry
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• 제42권4호
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• pp.175-179
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• 1999

Grape seed oil was extracted using different preparatory treatments as follows: (1) grinding, (2) grinding and roasting, (3) grinding and wet- roasting, (4) grinding, roasting, and wet-roasting, and (5) grinding, wet-roasting, and wet-roasting. The highest antioxidant activity was obtained from the sample with the method (2). Initial states of oxidation were similar except method (1) that showed more oxidized state, being P.O.V.8. Acid values were observed in the range from 1.42 to 1.89. The lowest acid value was found as 1.42 in method (1) and those of others were somewhat higher, indicating that heating process of roasting produced some free fatty acids. From the results of sensory evaluation, the best odor and taste were obtained from the methods (2) and (3). Repetitive procedure of wet-roasting, like method 5, caused some loss of flavor components and decrease in the sensory evaluation score. Addition of grape seed oil (method 2) to soybean and perilla oil at the level of 20% retained considerable antioxidant activities as much as 4.3 and 5 times, respectively, than 100% soybean or perilla oil stored for 12 weeks. When soybean or perilla oil was mixed with 20% grape seed oils, P.O.V. decreased to half of that of unmixed oils.

• Journal of Korean Biological Nursing Science
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• 제15권2호
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• pp.90-98
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• 2013

Purpose: The purpose of this study was to develop a clinical practice nursing students' microbiology program based on the mastery learning model, and to evaluate the effects of the program on nursing students' knowledge, self-efficacy, performance, and satisfaction related to the nursing students' microbiology program. Methods: The program was developed by using the processes of the mastery learning model. The pre-experimental research design involved a one group pretest-posttest design. The setting was a university located in Incheon, Korea. A total of 130 nursing students participated in the program including a theoretical lecture, clinical practice, and formative and summative evaluation. Results: Using the program that was designed and developed, results for the total score of self-efficacy, knowledge, and performance in the post-test application were significantly higher than in the pre-test application (p<.05). The satisfaction of hand hygiene and disinfection/contaminated hand microbial culture and disinfection test received the highest ratings. Conclusion: The application of a clinical practice nursing students' microbiology program was effective, and can be expanded to other nursing students. Future research with other study designs was warranted in order to prove the effect of a microbiology program based on the mastery learning model.

• Journal of Korean Biological Nursing Science
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• 제21권3호
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• pp.178-187
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• 2019

Purpose: The purpose of this study was to investigate how college students' perceived stress, cognitive stress, and somatization affect their heart rate variability (HRV). Methods: This study is a cross-sectional survey research on 191 university students, registered at the G University. The perceived stress scale (PSS) and cognitive stress response scale, were used to assess level of stress. The somatization symptom scale of the Symptom Check List 90 (SCL-90), was used to assess level of somatization caused by stress. To assess heart rate variability (HRV), we conducted a five-minute test using a pulse wave analyzer, to analyze short-term HRV. Results: The SCL-90 somatization score had relatively high positive correlation (p< .001) with cognitive stress, but low positive correlation (p< .001) with perceived stress. Cognitive stress response had low negative correlation (p< .001) with 1nSDNN and 1nRMSSD among HRV parameters. Perceived stress was not correlated with HRV. Multiple regression analysis showed that variables of perceived stress, cognitive stress, and somatization symptoms, could not explain HRV. By contrast, one of the HRV indicators, 1nSDNN, was affected by age, gender, and aggressive-hostile thought, the latter being a subscale of the cognitive stress response scale. Conclusion: This study suggests that stress evaluation for people in early adulthood will be more effective, if the evaluation examines cognitive stress and heart rate variability.

• KSBB Journal
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• 제25권6호
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• pp.572-576
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• 2010

수두 생바이러스 백신과 같은 생물의약품은 다양한 물질이 복합적으로 구성되어 있어 단순한 물리 화학적 분석방법만으로는 그 특성을 규명할 수 없다. 따라서 이러한 생물의 약품의 품질을 평가하기 위해서는 표준품이 필수적이다. 2002년과 2003년에 제조 및 확립한 1차 국가표준품의 재고량 소진 및 역가 감소에 따라 식품의약품안전평가원에서는 수두 생바이러스 백신의 2차 국가표준품을 확립하기 위하여 2008년 용역연구사업을 통해 국내의 수두 생바이러스 백신 제조회사에서 표준품 후보물질을 제조하였으며, 국가표준품 후보물질의 역가산정을 위하여 국내 제조사 및 식품의약품 안전평가원에서 공동연구를 수행하였다. 국내제조사를 포함한 3개의 공동연구 시험소에서 7회 이상의 반복시험을 수행하여 얻은 공동연구 결과를 통계학적으로 분석한 결과 3곳의 공동연구 시험소의 통합역가에 대한 변이계수 (coefficient variation, CV)는 1.24%로 각 시험소간의 기하평균 (GMT) 변동 수준이 매우 낮음을 확인할 수 있었다. 또한, 수두 생바이러스 백신의 2차 국가표준품의 표시역가는 $4.26\;log_{10}\;PFU$/0.5 mL로 산정하였다.

• Journal of Plant Biotechnology
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• 제36권4호
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• pp.360-365
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• 2009

Over the last five years, we have conducted research on risk assessment of domestically developed genetically modified (GM) crops and found a number of factors which could delay risk assessment process. In this review, we described such cases and discussed the problem of transgene cassette integration, the lack of information on vectors, the poor quality control in seed production and absence of bioinformatic analysis on amino acid sequence homology before GM crop development. To solve these problems, we have suggested the introduction of the screening system of elite event before risk assessment process and quality control strategies for GM seed production. In addition, we suggested that the developers of GM crops should understand the importance of risk assessment and management for the commercialization of those crops and consider the biological and ecological characteristics of host plants. Consistent communications may need to be established between GM crop developers, risk assessors and risk managers at the initial stages of GM crop development to reduce trial-and-errors.

• 대한환경공학회지
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• 제32권1호
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• pp.97-104
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• 2010

현재 강화된 방류수 수질 기준에 발맞춰 질소 인 제거를 포함한 고도처리 공정을 건설 중이거나 기존 표준활성슬러지 공정에서 고도처리공정으로의 개선이 추진되어지고 있다. 그러나 다양한 고도처리공정의 적용을 검토함에 있어 제거 효율 측면에서의 단순 평가만이 사용되고 있다. 따라서 고도처리공정 적용 시 제거 효율 뿐 아니라 슬러지 생산, 포기 비용 등을 복합적으로 평가할 수 있는 방법이 필요하였다. 따라서 본 연구에서는 표준활성슬러지 공정으로 운영 중인 S 하수처리장을 Biological nutrient removal(BNR) 공정으로 개선할 경우를 가정한 대안 공정 평가 방법을 제안하였다. 시간적, 비용적 장점을 가지며 객관적인 평가 기준으로 대두되고 있는 수학적 모델을 이용한 시뮬레이션을 통해 대안 공정으로 선정된 Anaerobic/anoxic/oxic ($A^2$/O), Virginia initiative plant (VIP), Daewoo nutrient removal (DNR) 공정에 대해 평가하였다. 시뮬레이션 결과를 바탕으로 공정의 처리 성능 뿐 아니라 슬러지 생산량 및 에너지 효율을 포함한 5가지 성능 지수들을 적용함으로써 개별 항목간의 비교 평가가 가능하였으며, 최적 공정을 제시하기 위한 객관적 판단과정을 퍼지 추론을 통하여 구현하였다.