Browse > Article
http://dx.doi.org/10.15269/JKSOEH.2016.26.4.396

Evaluation of Bisphenol A-Epichlorohydrin Exposure Workers in Apartment Building Construction: Pilot Study  

Shin, Wonho (Department of Industrial Health, Catholic University of Pusan)
Moon, Chan-Seok (Department of Industrial Health, Catholic University of Pusan)
Publication Information
Journal of Korean Society of Occupational and Environmental Hygiene / v.26, no.4, 2016 , pp. 396-403 More about this Journal
Abstract
Objectives: The study is to evaluate biological monitoring and risk assessment for epichlorohydrin-bisphenol A resin exposed from waterproofing or finishing work in the apartment building construction. Methods: Subjected workers were working on spray-painting and waterproofing work for 8 hours per day every 20 days. The urine samples were collected at the end of 20 days working period. For urinary bisphenol A as metabolite from epichlorohydrin-bisphenol A exposure, urine samples were analyzed with liquid chromatography mass-mass spectrometry(HPLC-MS/MS). Results: Geometric means of urinary bisphenol A(BPA) with no hydrolysis and with enzymic hydrolysis(BPA-EH) in the workers were $1.10{\mu}g/L$ and $2.90{\mu}g/L$. BPA-EH was 4 times higher than that of control group. The factors for working period and ages did not affect the variation of BPA and BPA-EH. The levels for BPA and BPA-EH were not higher than 95th percentile for exposure on human-life environment. Conclusions: The BPA and BPA-EH were therefore effective biological markers for epichlorohydrin-bisphenol A exposure workers, but not seem to hazardous exposure level. Waterproofing work in construction workshop is required to measuring work environment and health care management for the workers.
Keywords
Bisphenol A; construction work; evaluation; urine; waterproof;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Melzer D, Osborne NJ, Henley WE, Cipelli R, Young A et al. Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women. Circulation. 2012 Mar 27;125(12):1482-1490   DOI
2 Miao M, Yuan W, Yang F, Liang H, Zhou Z et al. Associations between bisphenol A exposure and reproductive hormones among female workers. Int J Environ Res Public Health 2015;12(10):13240-13250   DOI
3 National Institute of Environmental Research(NIER). The first stage('09-'11) 1st year annual report on Korean national environmental health survey. 2009. p. 178
4 Angelini G, Rigano L, Foti C, Grandolfo M, Vena GA et al. Occupational sensitization to epoxy resin and reactive diluents in marble workers. Contact Dermatitis 1996;35(1):11-16   DOI
5 Choi SJ. A study on health protection methods for irregular construction workers at Yeosu National Industrial Complex. OSHRI 2007
6 Duan B, Hu X, Zhao H, Qin J, Luo J. The relationship between urinary bisphenol A levels and meningioma in Chinese adults. Int J Clin Oncol. 2013;18(3):492-497   DOI
7 Hannu T, Frilander H, Kauppi P, Kuuliala O, Alanko K. IgE-mediated occupational asthma from epoxy resin. Int Arch Allergy Immunol 2009;148(1):41-4   DOI
8 Hehn RS. NHANES Data Support Link between Handling of Thermal Paper Receipts and Increased Urinary Bisphenol A Excretion. Environ Sci Technol 2015(in printing).
9 Hyoung UJ. Developmental toxicity study of bisphenol A diglycidyl ether in Sprague-Dawley male rats during pregnancy and lactation. Thesis for doctor course, Major in Preventive Medicine Department of Medical Science, Graduate School, Chung-Ang University 2006
10 Im CJ, Kim BI. An adhesive method of asphalt pavement for steel bridge deck using silica sand and epoxy resin. Conference on Korean Society of Civil Engineering. 2002;11:2005-2008 p. 4
11 Jolanki R, Kanerva L, Estlander T. Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet-light-cured paint, and bisphenol A in dental composite resin. Contact Dermatitis 1995;33(2):94-99   DOI
12 Völkel W, Bittner N, Dekant W. Quantitation of bisphenol A and bisohenol A glucuronide in biological samples by high performance liquid chromatography-tandem mass spectrometry. Drug Metab Dispos 2005;33:1748-1757   DOI
13 Isaksson M, Moller H, Ponten A. Occupational allergic contact dermatitis from epoxy resin in a golf club repairman. Dermatitis 2008;19(5):E30-32
14 Seo SK, Chae WB. Perfonuance Evaluation of Coating for Concrete Surface Finishing Synthesized Waterborne Epoxy Resin and Silane Coupling Agent. Journal of the institute of constructional technology. 2013;32:No.2
15 Sriram K, Jefferson AM, Lin GX, Afshari A, Zeidler-Erdely PC et al. Neurotoxicity following acute inhalation of aerosols generated during resistance spot weld-bonding of carbon steel. Inhal Toxicol 2014;26(12):720-732   DOI
16 Takeuchi T, Tsutsumi O, Ikezuki Y, Takai Y, Taketani Y. Positive relationship between androgen and the endocrine disruptor, bisphenol A, in normal women and women with ovarian dysfunction. Endocr J. 2004;51(2):165-169   DOI
17 van Joost T. Occupational sensitization to epichlorohydrin and epoxy resin. Contact Dermatitis 1988;19(4):278-280   DOI
18 Wang F, Hua J, Chen M, Xia Y, Zhang Q et al. High urinary bisphenol A concentrations in workers and possible laboratory abnormalities. Occup Environ Med 2012;69(9):679-684   DOI
19 Prens EP, de Jong G, van Joost T. Sensitization to epichlorohydrin and epoxy system components. Contact Dermatitis 1986;15(2):85-90   DOI
20 Yu TH. A Study on the epoxy-coated reinforcement bar performance in marine concrete structures. Thesis for master course, Dept. of Civil Engineering in Hanyana University 1996
21 Kanerva L, Pelttari M, Jolanki R, Alanko K, Estlander T et al. Occupational contact urticaria from diglycidyl ether of bisphenol A epoxy resin. Allergy 2002; 57(12):1205-1207   DOI
22 Kim EJ. A study on self-reported status of multiple chemical sensitivity by job groups in construction worker and VOCs exposure rate. Thesis for master course, dept. of Interior Environmental Design The Graduate School of Human Environmental Science, Yonsei University 2005 p.12-13
23 Kim M, Kim D, Hwang S, Park J, Seo C et al. A Case of Allergic Contact Dermatitis Caused by Epichlorohydrin and tris-DMP in an Epoxy Resin Worker. Korean J Occup Environ Med 2009;21(3):276-282
24 Ko A, Hwang MS, Park J-H, Kang H-S, Lee H-S et al. Association between urinary bisphenol A and waist circumference in Korean adults. Toxicol Res(Official Journal of Korean Society of toxicology) 2014;30(1):39-44   DOI
25 Korea Food & Drug Administration. Bisphenol A Risk Profile. 2010. p.3
26 KOSHA. Epichlorohydrin-bisphenol A resin, Material Safety Data Sheet. CAS No. 25068-38-6. 2014
27 Lee HR. Development of epoxy resin-based chloride sensor. Thesis for master course, Dept. of Chemistry in Kwangwoon University 2003
28 Li DK, Zhou Z, Miao M, He Y, Qing D et al. Relationship between urine bisphenol-A level and declining male sexual function. J Androl. 2010;31(5):500-506   DOI