• 대한의생명과학회지
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• 제11권2호
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• pp.237-242
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• 2005

The Hovenia extracts showed a significant hepato-protective activity against alcohol and CC4-induced hepatotoxicity. Injection of CC4 and alcohol induced liver injury and increased serum GOT (glutamic oxaloacetic transaminase) and GPT (glutamic pyuvic transaminase) levels in injured rats. The ADH (alcohol dehydrogenase)-like and ALDH (aldehyde dehydrogenase)-like activities in the Hovenia extracts were studied. Their activities in the extracts of Hovenia wood were higher than the extracts of other parts of Hovenia. And then Hovenia wood extracts have high effects on the alcohol and acetealdehyde degradation. The Hovenia extracts were decreased concentration of fusel oil. The ADH-like and ALDH-like activities in the Hovenia wood extract were 1.14 $unit/{\mu}l$, 0.33$unit/{\mu}l$ respectively.

• Journal of Applied Biological Chemistry
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• 제60권3호
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• pp.207-211
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• 2017

It is introduced an outstanding book about an important topic in occupational and environmental sciences i.e., the opportunities and challenges that may be connected with increasing the use and distribution of rare earth elements. These chemically similar elements, comprising the lanthanides, scandium, and yttrium, are involved in a number of essential technological applications, and their effects raise a number of human health issues of relevance to the occupational and environmental sciences. The book that I introduced here, "Rare Earth Elements in Human and Environmental Health; At the Crossroads between Toxicity and Safety" edited by Giovanni Pagano (Pan Stanford Publishing Pte. Ltd., Temasek Boulevard, Singapore) represents a break from that situation. It is essential to increase our knowledge about the environmental fate and biological effects of these technologically important metals in order to prevent unforeseen long-term man-made consequences to human health. This book is likely to become an important resource for scientists, engineers, and decision makers who understand the need for sensible exploitation of this resource.

• 대한약리학회지
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• 제11권1호
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• pp.61-79
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• 1975

The recent knowledge about the effects and the biological roles of prostaglandins(PGs) in the female reproductive system were reviewed on the following view points in detail and the authors also argued on the efficacy and reliability for the induction of labour and therapeutic abortions in midtrimester pregnancy. 1. The actions of PGs on the myometrium in vivo and in vitro and the effects of ovarian hormones on the actions of PGs. 2. The actions of PGs on the fallopian tube. 3. The role of PGs in the initiation of menstrual bleeding and dysmenorrhea. 4. The biological action of PGs on the mechanism of labour and parturition. 5. The efficacy and reliability of PGs for therapeutic abortion in the first and midtrimester pregnancy. 6. The biological role of PGs in the activity and life-span of corpus luteum.

• Applied Microscopy
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• 제45권3호
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• pp.150-154
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• 2015

Negative staining electron microscopy facilitates the visualization of small bio-materials such as proteins; thus, many electron microscopists have used this conventional method to visualize the morphologies and structures of biological materials. To achieve sufficient contrast of the materials, a number of imaging parameters must be considered. Here, we examined the effects of one of the fundamental imaging parameters, electron beam exposure time, on electron densities generated using transmission electron microscopy. A single site of a negatively stained biological sample was illuminated with the electron beam for different times (1, 2, or 4 seconds) and sets of micrographs were collected. Computational image processing demonstrated that longer exposure times provide better electron densities at the molecular level. This report describes technical procedures for testing parameters that allow enhanced evaluations of the densities of electron microscopy images.

• Journal of Plant Biotechnology
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• 제41권1호
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• pp.44-49
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• 2014

In this study, we investigated the effects of sodium hypochlorite (NaOCl) and red or blue light-emitting diode (LED) light on embryo swelling and germination of Oreorchis patens (Lindl.) Lindl. A method for determining the swelling and protocorm formation in O. patens seeds through in vitro examination of immature seeds was established. NaOCl treatment of immature seeds was found to significantly enhance the extent of embryo swelling and protocorm formation in immature zygote embryos compared to those in the untreated controls. Additionally, the effects of white fluorescent light, and red and blue LED lights on embryo swelling and protocorm formation in in vitro cultured seeds were examined and compared to the conditions with or without NaOCl treatment. The most suitable light for embryo swelling and protocorm formation was the red LED light.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.99.1-99.1
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• 2003

Cinnamaldehyde is the main component of cinnamon bark oil and show several biological activities such as anti-tumor, anti-fungal, anti-mutagenic and anti-inflammatory effects. A couple of studies have investigated how the natural compound exerts its anti-inflammatory effect. In despite of numerous investigations, the biological mechanism of effects belong to cinnamaldehyde remain unclear. We isolated 2-hydroxycinnamaldehyde(HCA) from the bark of Cinnamomun cassia Blume and reported a various of biological activities of HCA. (omitted)

• International Journal of Industrial Entomology and Biomaterials
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• 제45권1호
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• pp.17-21
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• 2022

The present study aimed to determine whether a hemolymph prepared from Antheraea yamamai larvae had the same biological activities using a Bombyx mori hemolymph prior to exposure to lipopolysaccharide (LPS) in order to induce an inflammatory response. The effects of the hemolymph were determined using a reverse transcription-quantitative polymerase chain reaction to assess the expression of pro-inflammatory molecules. The A. yamamai hemolymph exerted anti-inflammatory effects on LPS-activated human monocytic leukemia cells via Toll-like receptor (TLR) 4-mediated suppression, similar to the B. mori hemocyte extract. Treatment with the A. yamamai hemolymph significantly suppressed LPS-induced upregulated inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) mRNA expression at all tested concentrations compared with the control, similar to the B. mori immune-challenged hemolymph. Finally, the A. yamamai hemolymph, like the B. mori immune-challenged hemolymph, suppressed all of these concentrations in a dose-independent manner. These results demonstrate that the hemolymph of A. yamamai exhibited important biologically active substances. Further in-depth functional studies are required to fully understand the mechanisms underlying the biological activities of wild-type silkworm hemolymphs.

• Carbon letters
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• 제17권1호
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• pp.74-78
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• 2016

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2005년도 춘계학술대회 및 국제심포지움 초록집
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• pp.40-40
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• 2005

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 춘계학술대회 논문집
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• pp.41-42
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• 2003

Matrix metalloproteinases (MMPs) inhibitors were screened from Metasequoia glyptostroboides and one potent inhibitor, dihydrohinokiflavone (DHHF), a biflavonoid, was selected. DHHF inhibited proliferation of HT1080, human fibrosarcoma cells in a dose-dependent manner. Noncytotoxic levels of DHHF dramatically decreased MMP-9 and MMP-2 production in unistimulated cells, but did not change the level of tissue inhibited of metalloproteinase (TIMP)-1, an inhibitor of MMP-9.(omitted)