• Journal of The Korean Association For Science Education
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• v.12 no.2
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• pp.1-18
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• 1992

The curriculum especially in Korea plays a crucial role in developing instructional materials. It serves as a criterion for selecting and organizing content of teaching materials. Therefore, the validity of a curriculum can be justified through testing effectiveness of an instructional material developed in accordance with the curriculum. This paper presents an instructional method and material developed based on the current tendency of educational thoughts that emphasize STS and students - centered teaching strategies in science education. The instructional material was organized around the concept and its subconcept of "nutrition" as presented in the high school biology textbooks now in use in the nation as well as in a few world-wide countries. It was also organized by the use of biological events and phenomena which high school students in rural areas can easily encounter through their everyday lives. The significant findings in this study are : ${\circ}$ The achievement levels in experimental groups were higher than one in controlled groups. ${\circ}$ The students as well as the teachers involved in this study showed positive attitude toward the instructional method developed in the process of this study. ${\circ}$ The greater part of the students among the controlled groups hoped that biology would be taught by this kind of teaching procedure and materials.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.13 no.6
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• pp.30-36
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• 2014

Many different cells types have been found to be highly sensitive to mechanical force imposed by their surroundings. The cellular response to external mechanical forces has very important effects on numerous biological phenomena. In spite of its importance in biological processes, the cell adhesion force remains difficult to measure quantitatively at the cellular level. In this paper, to enhance quantitative measurements of cell adhesive interactions, a new attaching system and a method in which a glass bead can be attached to an AFM cantilever was designed and fabricated, and the degree of range displacement was controlled in the system. In an experiment, the movement of the stage in the attaching system and the attaching process were measured. The effectiveness of this system was confirmed as well in the experiment. In addition, through a commercial AFM system, the spring constant of the modified AFM probe could be measured.

• Journal of Korean Biological Nursing Science
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• v.21 no.4
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• pp.318-325
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• 2019

Purpose: The purpose of this study was to identify the effects of a finger guard developed to prevent sharp injuries in nursing students. Methods: This study was an equivalent control group posttest design. Seventy nursing students were randomly allocated to either the experimental group (n= 35) or the control group (n= 35). The finger guard was used whileopening the glass ampoule in the experimental group. The outcome variables such as sharp injuries, anxiety and user satisfaction were measured. Results: Sharp injuries were 0 in the experimental group and 2 in the control group (p= .160). Anxiety in the experimental group was significantly lower than the control group (p< .001). User satisfaction was 4.33 score in the range from 1 to 5, the highest item was the weight (4.63), followed by effectiveness (4.51). Conclusion: Using a protective device while opening the glass ampoule was observed to be effective in reducing anxiety among the nursing students, and exhibited protection of skin.

• Journal of Applied Biological Chemistry
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• v.61 no.4
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• pp.383-389
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• 2018

Degradation of the insecticide O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate (chlorpyrifos) in aqueous solution was investigated using iron salts and potassium persulfate during ZVI treatment through a series of batch experiments. The degradation rate of chlorpyrifos increased with increases in the concentrations of iron salts and potassium persulfate in the aqueous system. Ferric chloride was found to be the most effective iron salt for the ZVI-mediated degradation of chlorpyrifos in aqueous solution. Further, the iron salts tested could be arranged in the following order in terms of their effectiveness: $FeCl_3$> $Fe_2(SO_4)_3$> $Fe(NO_3)_3$. The persulfate-ZVI system could significantly degrade chlorpyrifos present in the aqueous medium. This revealed that chlorpyrifos degradation by treatment with $Fe^0$ was promoted on adding ferric chloride and potassium persulfate. The kinetics of the degradation of chlorpyrifos by persulfate-amended $Fe^0$ was higher than that for iron-salt-amended $Fe^0$. This suggests that using a sequential $Fe^0$ reduction-ferric chloride or $Fe^0$ reduction-persulfate process may be an effective strategy to enhance the removal of chlorpyrifos in contaminated water.

• Journal of Korean Biological Nursing Science
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• v.21 no.3
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• pp.199-206
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• 2019

Purpose: The purpose of this paper was to verify effects of the team approach rehabilitation program on balance, gait, and muscle strength of lower extremities of elderly people with Parkinson's disease. Method: Subjects of this paper were 40 elderly people with Parkinson's disease, 20 control and experimental groups respectively, who could walk independently and were less than the 2.5 Hoehn &Yahr stage. The team approach rehabilitation program was applied to the experimental group for 12 weeks. Results: There was significant decrease in second at timed up &go test (p= .008), but no significant difference in reach length at functional reach test (p= .201) with partial improvement of balance. There was no significant difference in second at 10-meter walk test (p= .070), but showed tendency of improvement of gait. And number of times at 30s-chair stand test, indicating muscle strength on lower extremities, increased significantly (p= .029), Conclusion: The team approach rehabilitation program has demonstrated its effectiveness on improving balance, and muscle strength of lower extremities for the elderly with Parkinson's disease.

• Journal of Korean Biological Nursing Science
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• v.25 no.2
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• pp.113-122
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• 2023

Purpose: The purpose of this study was to examine the effects of a mobile application on quality of life, wellness, and preventive behaviors against dementia among older adults who use senior citizen centers. Methods: Seventy-two older adults who used senior citizen centers were allocated to an intervention group (n = 36) and a control group (n = 36). The experimental treatment involved a cognitive enhancement program for preventing dementia using a mobile application for 12 sessions over 6 weeks. Data were analyzed using the t-test, chi-square test, Fisher's exact test, paired t-test, and independent t-test. Results: The cognitive enhancement program based on a mobile application was effective for wellness (t = -3.87, p < .001) and preventive behaviors against dementia (t = -3.98, p < .001) for older adults who used a senior center. Conclusion: The mobile application-based cognitive enhancement program developed in this study is recommended as an effective intervention for dementia prevention in older adults.

• Journal of Sasang Constitution and Immune Medicine
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• v.35 no.4
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• pp.10-22
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• 2023

Objectives The aim of this study is to explore the mechanism of action and target diseases of Sasang constitutional prescriptions using a multiscale interactome approach. Methods The compound and target information of Sasang constitutional prescriptions were retrieved from various databases such as the TM-MC, STITCH, and TTD. Key targets for Sasang constitutional prescriptions were identified by selecting the top 100 targets based on the number of simple paths within the constructed network. Diffusion profiles for Sasang constitutional prescriptions and diseases were calculated based on a biased random walk algorithm. Potential diseases and key mechanisms of Sasang constitutional prescriptions were identified by analyzing diffusion profiles. Results We identified 144 Sasang constitutional prescriptions and their targets, finding 80 herbs with effective biological targets. A cluster analysis based on selecting up to 100 key targets for each prescription revealed a more cohesive grouping of prescriptions according to Sasang constitution. We then predicted potential diseases for 62 Sasang constitutional prescriptions using diffusion profiles calculated on a multiscale interactome. Finally, our analysis of diffusion profiles revealed key targets and biological functions of prescriptions in obesity and diabetes. Conclusions This study demonstrates the effectiveness of a multiscale interactome approach in elucidating the complex mechanisms and potential therapeutic applications of prescriptions in Sasang constitutional medicine.

• Journal of Korean Biological Nursing Science
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• v.26 no.2
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• pp.71-82
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• 2024

Purpose: This study systematically analyzed the impact of aromatherapy on pain in individuals with diabetes. Methods: A search was performed in seven electronic databases based on the PICO-SD (Population, Intervention, Comparison, Outcome, Study Design) framework. The population (P) of interest was individuals with diabetes, and the intervention (I) included aromatherapy targeting pain reduction. The comparison (C) consisted of control groups that received no intervention, another intervention, or usual care. The outcome (O) measured was pain. The quality of the selected literature was assessed using the Joanna Briggs Institute checklist. In MIX 2.0 Pro, the pooled overall effect of pain was calculated using Hedge's g and a random-effects model, and heterogeneity was calculated using the Q statistic and Higgin's I2 values. Meta-regression and exclusion sensitivity analyses were performed. Results: Five articles and seven studies were included, showing a significant pooled overall effect of aromatherapy on diabetes-related pain (Hedge's g = -1.83, 95% CI: -2.76 to -0.91). Meta-regression demonstrated that effectiveness in reducing pain was associated with studies conducted in West Asia, those with IRB approval, and those receiving funding. Additionally, interventions involving subjects under 60, lavender oil (vs. turpentine oil or blended oils), massage therapy (vs. topical application), fewer hours per session, and more repeated measurements (vs. pre/post measurements) were associated with pain reduction. Conclusion: Aromatherapy, especially with lavender oil, effectively manages diabetes-related pain. Short-duration massage application is also effective. A personalized selection of oil type and application method could optimize therapeutic outcomes for individuals with diabetes.

• Journal of Korean Biological Nursing Science
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• v.26 no.2
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• pp.99-110
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• 2024

Purpose: This study reviewed the pathophysiological mechanisms of cellular aging caused by psychological stress and aimed to establish a biobehavioral theoretical framework for nursing interventions to promote autonomic balance based on these mechanisms. Methods: A comprehensive literature review was conducted. Results: A review of the literature showed that the stress response increases the secretion of catecholamines and glucocorticoids, resulting in a greater allostatic load. This load induces inflammatory reactions and oxidative stress, shortening telomere length and damaging mitochondrial DNA, which can lead to cellular aging. Based on this mechanism, a biobehavioral theoretical framework for nursing interventions was established. This framework focuses on delaying or inhibiting the cellular aging process by acting on the stress response stage and improving autonomic balance. Conclusion: According to the proposed biobehavioral theoretical framework, stress-relieving nursing interventions may act on the mechanism of cellular aging caused by stress responses. We believe that this framework could expand our understanding of the biobehavioral aspects of stress and would facilitate efforts to use biomarkers to evaluate the effectiveness of stress-related nursing interventions at the cellular level.

• Corrosion Science and Technology
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• v.23 no.1
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• pp.72-81
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• 2024

The Ti-6Al-4V alloy is widely used as an implant material due to its higher fatigue strength and strengthto-weight ratio compared to pure titanium, excellent corrosion resistance, and bone-like properties that promote osseointegration. For rapid osseointegration, the adhesion between the titanium surface and cellular biomolecules is crucial because adhesion, morphology, function, and proliferation are influenced by surface characteristics. Polymeric peptides and similar coating technologies have limited effectiveness, prompting a demand for alternative materials. There is growing interest in 2D nanomaterials, such as MoS₂, for good corrosion resistance and antibacterial, and bioactive properties. However, to coat MoS₂ thin films onto titanium, typically a low-temperature hydrothermal synthesis method is required, resulting in the synthesis of films with a toxic 1T@2H crystalline structure. In this study, through high-temperature annealing, we transformed them into a non-toxic 2H structure. The implant coating technique proposed in this study has good corrosion resistance and biocompatibility, and antibacterial properties.