• Title/Summary/Keyword: Biochemical indices

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Nutritional Status and Indicators of Immune Function of Elderly Residing in Low Income Urban Area (도시생활보호노인들의 영양상태와 면역지표에 관한 연구)

  • 손숙미;윤혜영
    • Korean Journal of Community Nutrition
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    • v.2 no.4
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    • pp.547-555
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    • 1997
  • This study was conducted to assess the nutritional status of the elderly from low income areas and its relationship with the indices of immunity. Ninety nine(male : 28, female : 71) healthy, subjects aged over 65 years staying in homes in Seoul were assessed with regard to their dietary intake and biochemical measurements. Their mean daily energy intakes were 1256kcal and 109kcal for males and females respectively. Mean serum IgG were 2356mg/dl in men and 2161mg/dl for women, higher than the normal range. Mean serum $C_3$ were 120.9mg/dl and 130.6mg/dl for males and females respectively and mean $C_4$ were 30.6mg/dl and 31.9mg/dl. The mean $C_3$ and $C_4$ were within the normal range and the proportion of subjects whose $C_3$ and $C_4$ were at a higher level than the upper limit were 15.4$\%$ and 16.3$\%$ respectively. Complement $C_3$ showed significant correlation with serum albumin(p〈0.01), serum cholesterol(p〈0.00l, serum TG(p〈0.05), LDL-C(p$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$$\ll$q0.001), VLDL-C(p$\ll$0.05), serum copper(p$\ll$0.05) and serum Ca(p$\ll$0.01). (Korean J Community Nutrition 2(4) : 547-555, 1997)

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A study on Nutritional Status and Eating Behaviors of Underweight Adolescent Boys Using 2001 NHANS of Korea (저체중인 남자 청소년의 영양상태과 식행동 특성 - 2001년 국민건강.영양조사 대상자를 중심으로 -)

  • Kwon, Min-Kyung;Park, Young-Sook
    • Korean Journal of Community Nutrition
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    • v.12 no.3
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    • pp.235-246
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    • 2007
  • This study was performed to identify nutritional status and eating behaviors of underweight male adolescents aged 15 to 19 years. The subjects selected by using the data of KNHANS-2001 were 32 underweight boys and 135 normalweight ones. We found that weight, waist and hip circumference of the underweight group were significantly different to normal-wight group, but height and waist-hip ratio were not. Their serum indices belonged within normal ranges and showed no difference between the two groups. Their energy and nutrient intakes were mostly poor. The level and proportion of the subjects below EAR, NAR and INQ of each nutrient were not significantly different between the two groups. There were no difference of frequencies of skipping meals, snacking and eating-out between the two groups, either. When comparing frequencies of food intakes, the underweight group consumed significantly more of fermented fishes and less milk than the normal-weight group. And the former had significantly more rest/sleep, no-does and supplementation and less regular excercise than the latter. The underweight group perceived more correct self-images than the normal-weight group and they tried more to increase their body weight during weight control practice (p<0.001). It was concluded that the underweight group showed no different biochemical indices, nutrient intakes, and dietary behaviors to the normal-weight group, but they revealed significantly higher non-active activities like rest and supplementations.

Study of depression risk factors in simple labor occupation group (단순노무종사자 직업군에서의 우울증 위험요인 연구)

  • Lee, Bum Ju
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.4
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    • pp.253-258
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    • 2020
  • Depression is a disease with an increasing prevalence worldwide, and is highly associated with mortality as well as several diseases such as hypertension. The aim of this study is to discover clinical risk indicators associated with depression in the occupational group of simple labor workers. This study used the Seventh Korean National Health and Nutrition Examination Survey (2016-2018) conducted by the Korea Centers for Disease Control and Prevention. In association between depression and demographic information, age, sex, degree of stress perception, and stress perception ratio indices had a very high statistical association with depression, and education level and marital status were also associated with depression. Obesity indices such as abdominal circumference and body mass index were not associated with depression. Among the blood information, hemoglobin and hematocrit were highly associated with depression, and statistical significance was maintained even in the analysis adjusted for sex and age. The results of this study can be used as information for the prevention and treatment of depression in the occupational group of simple labor workers in the future.

Influence of Epinephrine and Norepinephrine on the Risk of Metabolic Syndrome Occurrence in Workers Exposed to Hazardous Chemicals (유해화학물질 노출 근로자의 대사증후군 발생위험에 대한 epinephrine과 norepinephrine의 영향)

  • Heo, Kyung-Hwa;Kim, Ki-Woong
    • Korean Journal of Occupational Health Nursing
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    • v.19 no.1
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    • pp.88-96
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    • 2010
  • Purpose: The aim of the present study was to clarify effects of long term, low-level monocyclic aromatic hydrocarbons exposure (MAHs) such as styrene, toluene and xylene on physiological levels of epinephrine (EP) and norepinephrine (NEP) and these hormones influences diagnosis indices of metabolic syndrome (MetS). Methods: Blood pressure and serum biochemical parameters were measured using digital sphygmomanometer and autochemical analyzer. EP and NEP were analyzed by using ELISA kit and exposure level of MAHs was measured by NIOSH method. Results: The differences of general characteristics such as age, smoking and drinking habits in both groups were not significantly different except working hours per day. In exposed workers, exposure levels of MAHs showed very low concentrations. Serum HDL-cholesterol concentration was significantly higher in exposed group, but concentration of NEP was significantly higher in control group. On multiple logistic regression analysis for the diagnosis indices of MetS, EP was WC (OR=0.970), NEP was blood pressure (OR=1.002) and MAHs exposure were significantly associated with HDL-cholesterol (OR=0.257), fasting glucose (OR=3.028) and MetS (OR=0.372). Conclusion: These findings suggest that the chronic exposure of low level MAHs maycontribute to glucose metabolism and induction of MetS. And also, changes of EP and NEP levels by exposure of MAHs affect blood pressure.

The effect of genistein on insulin resistance, inflammatory factors, lipid profile, and histopathologic indices in rats with polycystic ovary syndrome

  • Amanat, Sasan;Ashkar, Fatemeh;Eftekhari, Mohammad Hassan;Tanideh, Nader;Doaei, Saeid;Gholamalizadeh, Maryam;Koohpeyma, Farhad;Mokhtari, Maral
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.3
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    • pp.236-244
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    • 2021
  • Objective: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, irregular menstruation, ovulatory dysfunction, and insulin resistance. Recent studies have reported the possible role of phytoestrogens in PCOS. This animal study aimed to evaluate the effects of genistein on insulin resistance, inflammatory factors, lipid profile, and histopathologic indices on PCOS. Methods: PCOS was induced by 1 mg/kg of letrozole in adult Sprague-Dawley rats. The rats then received normal saline (PCOS group), 150 mg/kg of metformin, or 20 mg/kg of genistein dissolved in 1% methylcellulose solution for 42 days. Body weight, the glycemic and lipid profile, and inflammatory, antioxidative, and histopathological parameters were assessed at the end of the intervention. Results: Treatment with genistein significantly alleviated the increased level of fasting blood insulin (p=0.16) and the homeostatic model assessment of insulin resistance (p=0.012). In addition, the genistein group had significantly lower levels of serum malondialdehyde (p=0.039) and tumor necrosis factor-alpha (p=0.003), and higher superoxide dismutase enzyme activity (p<0.001). Furthermore, the histopathological analysis indicated that genistein administration led to an increase in luteinization and the development of fewer cysts (p<0.05). Conclusion: Biochemical and histopathological analyses indicated that genistein administration to rats with PCOS induced significant remission in oxidative, inflammatory, and glycemic and histopathologic parameters.

Development of Benthic Macroinvertebrates Family-Level Biotic Index for Biological Assessment on Korean Stream Environment (한국의 하천환경 평가를 위한 저서성 대형무척추동물의 과 범주 생물지수 개발)

  • Kong, Dongsoo;Min, Jeong-Ki;Noh, Seong-Yoo
    • Journal of Korean Society on Water Environment
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    • v.35 no.2
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    • pp.152-164
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    • 2019
  • In this study, a Benthic Macroinvertebrates Family Index (BMFI) was developed using 100 indicator groups (99 families including Chironomidae with 2 phena). Families were assigned a score between 1 and 10 depending on their sensitivity to organic pollution. The BMFI was composed of the sensitivity and relative abundance of the indicator taxa. Sensitivity values of each group were generally similar to Biological Monitoring Working Party (BMWP) scores or Walley, Hawkes, Paisley, Trigg (WHPT) scores of UK, Japanese BMWP scores, and the FBI tolerance values of North America. However, sensitivity values of some taxa were significantly different from those of foreign countries, which seemed to have resulted from discrepancy in species composition, difference of taxonomic classification system, or methodological difference for estimation of sensitivity. As an annual average level, BMFI showed significant correlation with concentration of 5-day biochemical oxygen demand (BOD5) (correlation coefficient r = -0.80, n = 569 sites), total suspended solids (r = -0.68), and total phosphorus (r = -0.79). In addition, BMFI revealed strong correlation with Shannon-Weaver's species diversity (r = 0.85), Margalef's species richness (r = 0.85) and McNaughton's dominance (r = -0.84). Correlation between BMFI and water quality parameters or community indices such as species diversity did not show significant difference compared to that of species-level indices such as BMI (Benthic Macroinvertebrates Index). This means that BMFI is a more useful indicator in terms of easy identification of organisms. BMFI was used to assess the environmental status of 3,017 sites of Stream Ecosystem Survey conducted by the Korean Ministry of Environment between 2016 and 2018. As a result, about half of all sites appeared to be in good condition, and a quarter in poor condition.

Development of Estimation Indices for Refractory Organic Matter in the Han-River Basin using Organic Matter Parameters and Spectroscopic Characteristics (일반 유기물 항목과 분광특성을 이용한 한강수계 내 난분해성 물질 지표 제시)

  • Lee, Bomi;Lee, Tae-Hwan;Hur, Jin
    • Journal of Korean Society on Water Environment
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    • v.27 no.5
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    • pp.625-633
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    • 2011
  • A long-term water quality monitoring in the Han River Basin reveals a consistent increasing trend for the concentration of refractory organic matter (R-OM) in major monitoring sites of the watershed. Because the determination of R-OM concentrations typically requires a long time of microbial incubation, it is essential to present the estimation indices for R-OM for an efficient watershed management. In this study, a number of surface water samples were classified into three groups, each of which were collected from Lake Paldang, rivers at rain and non-rain events, respectively. The corresponding R-OM concentrations were correlated with biochemical oxygen demand (BOD), chemical oxygen demand (COD), and total organic carbon (TOC) concentrations as well as ultraviolet and fluorescence intensities of the filtered samples. Among the traditional organic matter parameters, TOC exhibited the highest correlation coefficient with the R-OM concentrations regardless of the types of the sample groups. The equations for conversing TOC into R-OM concentrations were finally suggested as $0.43{\times}TOC+1.12$, $0.44{\times}TOC+0.61$, $0.24{\times}TOC+1.28$ for river samples at rain and non-rain events, and lake samples, respectively. TOC-BOD(C), the values of the TOC concentrations subtracted by carbon-converted BOD concentrations, was a good index for estimating the absolute concentrations of R-OM. UV absorbance at 254 nm was well correlated with R-OM concentrations of river samples while fluorescence intensities at 350 nm showed an excellent relationship with R-OM concentration of the lake samples. Our results suggests that simple spectroscopic parameters could be applied for in-situ monitoring tool techniques in watersheds.

Ecological health assessment of Mae Kha Canal, Chiang Mai Province, Thailand in 2023

  • Onalenna Manene;Nick Deadman;Chotiwut Techakijvej;Songyot Kullasoot;Pitak Sapewisut;Nattawut Sareein;Chitchol Phalaraksh
    • Journal of Ecology and Environment
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    • v.48 no.1
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    • pp.110-119
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    • 2024
  • Background: The Mae Kha Canal is one of Chiang Mai's most important waterways. It supports local agriculture, irrigation, and transportation as well as provides stormwater drainage to prevent floods. Due to the unregulated rapid urbanization of the city and lack of efficient waste and wastewater management systems over the past few decades, the canal has become heavily polluted. This study aimed to evaluate the water quality of Mae Kha canal through assessment of the physico-chemical water quality and coliform bacteria. Moreover, benthic macroinvertebrates were samples and assessed using the Biological Monitoring Working Party (BMWPThai) and Average Score Per Taxon (ASPTThai) as biological indices. Results: The physico-chemical showed low dissolved oxygen levels, high levels of ammonia and phosphates, and elevated levels of biochemical oxygen demand, indicating that the water quality had significantly deteriorated. The canal was found to be heavily polluted, with most sites falling into the polluted to very heavily polluted. Coliform bacteria analysis revealed alarmingly high levels of total coliform bacteria and fecal coliform bacteria in the canal. The BMWPThai and ASPTThai scores indicated poor to very poor water quality. Conclusions: The physico-chemical and coliform bacteria indicated that the water quality of the Mae Kha canal had significantly deteriorated. The biological indices also indicated the poor to very poor water quality. This study underscores the urgent need for comprehensive remediation efforts, emphasizing strategic planning, investment, and community engagement to revive the canal's ecological health and water quality.

Growth and clinical efficacy of fortified human milk and premature formula on very low birth weight infants (극소 저체중출생아에서 강화된 모유와 미숙아 전용분유가 성장 및 임상에 미치는 효과)

  • Chueh, Heewon;Kim, Myo Jing;Lee, Young-A;Jung, Jin-A
    • Clinical and Experimental Pediatrics
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    • v.51 no.7
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    • pp.704-712
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    • 2008
  • Purpose : A prospective, controlled trial was conducted to evaluate growth, efficacy, safety and nutritional status for very low birth weight infants fed with human milk fortified with Maeil human milk fortifier (Maeil $HMF^{(R)}$; Maeil Dairies Co., Ltd.). Methods : We enrolled 45 premature infants with a birth weight <1,500 g and gestational age <33 weeks, who were born at Dong-A University Hospital from October, 2006 through December, 2007. They were divided into 2 groups: infants in one group were fed with human milk fortified with $HMF^{(R)}$, and the second were fed with preterm formula. Growth, biochemical indices, feeding tolerance, and other adverse events in each group were assessed serially and compared relatively. Follow-up data were also collected after discharge at 1, 3, and 6 months corrected age. Results : Characteristics of the 2 groups including average gestational age, birth weight, sex, respiratory distress syndrome, patent ductus arteriosus, and other adverse events (sepsis, retinopathy of prematurity, and intraventricular hemorrhage) showed no significant difference. Average feeding start day ($8.00{\pm}3.27d$ vs. $8.86{\pm}5.37d$) (P=0.99) and the number of days required to reach full feeding after start feeding ($41.78{\pm}20.47d$ vs $36.86{\pm}20.63d$) (P=0.55) were not significantly different in the group fed human milk fortified with $HMF^{(R)}$ when compared with the group that was fed preterm formula. The duration of total parenteral nutrition and the incidence of feeding intolerance also showed no differences between the 2 groups. Although infants fed with human milk fortified with $HMF^{(R)}$ showed faster weight gain than those fed with preterm formula at the end stage of the admission period, other growth indices of the two groups showed no significant difference. No significant correlations were found between the 2 groups with regard to weight gain velocity, height gain velocity, head circumference velocity, and post-discharge follow up growth indices. Conclusion : Premature infants fed human milk fortified with $HMF^{(R)}$ showed no significant difference compared with those fed preterm formula in growth, biochemical indices, and adverse events. Using human milk fortifier can be an alternative choice for very low birth weight infants, who need high levels nutritional support even after discharge from NICU.

Effects of zinc sources and levels of zinc amino acid complex on growth performance, hematological and biochemical parameters in weanling pigs

  • Zhang, Yi;Ward, Terry Lynn;Ji, Fei;Peng, Chucai;Zhu, Lin;Gong, Limin;Dong, Bing
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.8
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    • pp.1267-1274
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    • 2018
  • Objective: The objective of the study was to investigate the effects of zinc amino acid complex (ZnAA) on growth performance, hematological and biochemical parameters in weanling pigs. Methods: In Exp. 1, a total of 216 Duroc${\times}$Landrace${\times}$Large White weanling pigs were assigned randomly to 6 dietary treatments. Each treatment had 6 replicates (pens) with 6 pigs each. The diets were corn-soybean meal based with supplementation of 0, 20, 40, 80, 120 mg Zn/kg from ZnAA or 40 mg Zn/kg from feed-grade zinc sulfate. The experiment lasted 42 days. In Exp. 2, a total of 180 weanling pigs were assigned randomly to 3 dietary treatments supplemented with 0, 80, or 800 mg Zn/kg from ZnAA. Results: In Exp. 1, pigs fed 40 to 80 mg Zn/kg from ZnAA had higher (p<0.05) average daily gain (ADG) than the unsupplemented group during d 0 to 14. During d 0 to 42, the pigs fed 20 to 120 mg Zn/kg from ZnAA had increased (p<0.05) ADG. Pigs fed 20 to 120 mg/kg Zn from ZnAA had lower feed:gain (p<0.05), increased the activity of serum Cu-Zn superoxide dismutase on d 14, and increased serum Zn levels on d 42 (p<0.05). In Exp. 2, pigs fed diets with 800 mg Zn/kg had increased average daily feed intake during d 15 to 28 (p<0.05) compared to the unsupplemented group. During d 0 to 28, the pigs fed supplemental Zn had increased ADG (p<0.05). On d 14 and d 28, pigs fed supplemental Zn had higher the serum alkaline phosphatase activities (p<0.05). No significant differences were observed in the hematological parameters and organ indices. Conclusion: Supplementation with 20 to 80 mg/kg Zn from ZnAA improved the growth performance in weaned pigs. The piglets can tolerate up to 800 mg/kg Zn from ZnAA with limited potential health effects.