• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제12권sup1호
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• pp.6-11
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• 2009

Nutritional assessment is based on anthropometric, clinical, dietary and biochemical data. There is a lack of studies about the propriety of biochemical indexes for the nutritional assessment in children despite biochemical data in pediatric population are different from them in adult's in many respects. Serum albumin is useful index to evaluate the severity of malnutrition. Hemoglobin and hematocrit tend to decrease in malnutrition on account of defect of iron metabolism and to increase in metabolic syndrome on account of enhancement of erythropoiesis. But, unlike adult, total lymphocyte count is not so useful biochemical indexes in children. We should consider pediatric characteristic when interpret biochemical indexes for nutritional assessment in children, and nutritional status in children should be assessed comprehensively with anthropometric, clinical, dietary and biochemical data.

• Child Health Nursing Research
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• 제18권3호
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• pp.119-126
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• 2012

Purpose: The purpose of this study was to examine and analyze the post operative fasting period of neonates in the intensive care unit (ICU) after receiving open heart surgery in order to provide optimal nutrition support for these neonates. The variables included biochemical nutrition indexes (albumin, total lymphocyte count, total cholesterol) and patient outcomes (duration of mechanical ventilation, ICU stay, hospital stay, infectious complication). Methods: The participants were 124 neonates in ICU after receiving open heart surgery, and the design of this study was to investigate their post operative fasting period retrospectively to analyze the biochemical nutrition indexes and patient outcomes according to post operative fasting period. Results: The results for 4 groups according to post operative fasting period showed that the group with less 48 hours of fasting had the best biochemical nutrition indexes and patient outcomes, followed by the 48-72 hour group, the 72-144 hour group, and the over 144 hour group. Conclusion: The results indicate that for new born babies receiving open heart surgery, the period of fasting after the operation should be minimized and tube feeding should be started as soon as possible.

• Journal of Nutrition and Health
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• 제29권5호
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• pp.507-516
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• 1996

This study was undertaken to estimate seasonal variation of riboflavin status and investigate the relationship between riboflavin intake and its biochemical status in rural women. Dietary intake was measured by determining both 24hr recall method and conventient method. The riboflavin intake was also estimated by food frequency method. Ribofiavin biochemeical status was assessed by erythrocyte glutathione reductase activity coefficient(EGR AC) and urinary riboflavin excretion. All information was repeatly collected in three seasons ; farming season (June), harvest season(October), nonfarming season(February). Mean daily riboflavin intake was below RDA for Koreans in all seasons. Cereal & pulse, vegetable were the primary sources of riboflavin intake and provided above 60% of the total dietary riboflavin intake in all seasons. Riboflavin biochemical status was significantly different among seasons(EGR AC P<0.005, 24hr urinary riboflavin excretion P<0.05), and riboflavin biochemical deficiency was highest in February. The mean values of EGR AC revealed riboflavin deficiency in all seasons. However the mean values of urinary riboflavin excretion were within the normal range except 24hr urinary riboflavin excretion in February. On the basis of EGR AC criteria, 44.7% of subjects were at risk of deficiency in June, 44.7% in October, 81.6% in February. Result of individual riboflavin status assessed by EGR AC or 24hr urinary riboflavin excretion criteria was quite alike. Urinary riboflavin excretion per gram of creatinine underestimated riboflavin deficiency. Significant correlations were observed among biochemical indexes. It also appeared that riboflavin intake measured by food frequency method showed significant correlation with biochemical indexes, especially high correlation with EGR AC (P<0.001). The results indicated that the prevalence of riboflavin deficiency seems to be high among rural women in all seasons and the inadequacy of dietary riboflavin intake was reflected in the abnormalcy of riboflavin biochemical status assessed by EGR, AC. Therefore EGR AC seems to be more sensitive measure of impaired riboflavin status compared to urinary excretion.

• Clinical and Experimental Pediatrics
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• 제52권2호
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• pp.167-175
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• 2009

목 적 : 소아를 대상으로 생화학적 영양지표들이 각각의 체질량지수군 간에서 어떤 차이를 보이는 지 분석하고, 영양상태의 평가로 생화학적 영양지표들이 유용한 것인가를 알아보기 위하여 이 연구를 시행하였다. 방 법 : 2006년 1월부터 2007년 12월까지 강릉 아산병원에 선택적 수술을 받기 위해 내원한 3세 이상 10세 미만의 소아 중 신체계측 자료와 수술 전 혈액검사 자료가 모두 있는 269명을 대상으로 하였다. 체질량지수에 따라 저체중군, 정상체중군, 과체중군, 비만군으로 나누고 각 군 간에 TLC, 혈색소, 적혈구용적, 혈청 알부민, 총콜레스테롤 등과 같은 생화학적 영양지표가 의미있는 차이를 보이는 지를 후향적으로 분석하였다. 결 과 : 모든 체질량지수군 간에서 TLC는 유의한 차이가 없었다. 하지만 혈청 알부민은 저체중군에서 유의하게 감소되어 있었다. 적혈구수, 혈색소, 적혈구용적과 혈청 총콜레스테롤은 과체중군 또는 비만군에서 정상체중군보다 유의한 증가를 보였다. MCH와 MCV는 모든 군에서 유의한 증가가 없어, 과체중군과 비만군의 혈색소 및 적혈구수 등의 증가는 철분대사 보다는 적혈구 조혈기능의 증강 때문으로 생각된다. 남자와 여자에서 유의한 생화학적 영양지표가 서로 다르게 나타났는데 남자에서는 네 체질량군 간에 적혈구수, 혈색소, 적혈구 용적, 혈청 총콜레스테롤이 일부 유의한 차이를 보인 반면 여자에서는 유의한 차이를 보이지 않았고 알부민만 저체중군과 정상체중군 사이에서 유의한 감소를 보였다. 결 론 : 소아를 대상으로 시행한 생화학적 영양지표 중 적혈구수, 혈색소, 적혈구 용적, 혈청 알부민 및 총콜레스테롤은 체질량지수와 연관성이 있었다. 하지만 여자는 저체중군에서 알부민만 유의한 감소를 보였을 뿐 나머지 생화학 영양지표들과의 통계적 유의성은 없었다. 이에 대해 더 많은 연구가 필요할 것으로 생각된다.

• Asian-Australasian Journal of Animal Sciences
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• 제19권6호
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• pp.872-876
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• 2006

The objective of this study was to evaluate Biocom (a protein source containing a high level of glutamine and alanyl-glutamine) as a replacement for glutamine (Gln) in nursery pig diets. Forty-two pigs (fourteen pigs per treatment) weaned at 28 d of age were used in a 28-d performance trial using three dietary treatments: control (no Gln), control supplemented with Gln or Biocom. The control diet was composed of corn, soybean meal, whey and fish meal. Individual body weight, pen feed disappearance and diarrhea were monitored. On d 0, 2, 7 and 14 postweaning, respectively, five pigs per treatment were selected and bled from the anterior vena cava to obtain five replicate samples of blood on each dietary treatment for determination of blood biochemical index. Dietary supplementation of Gln and Biocom did not influence performance, plasma Gln and total serum protein concentration (p>0.05). However, the addition of Gln and Biocom could prevent serum urea nitrogen and serum cortisol from increasing on d 2 postweaning (p<0.05). There were no significant differences (p>0.05) in any of the examined parameters between Gln- and Biocom-supplemented diets. In conclusion, dietary Gln did not influence the performance of early-weaned piglets owing to the complex diet containing whey, but could prevent the increase of serum urea and cortisol. Biocom could be used as a replacement for free pure Gln without any negative effect on early-weaned piglets.

• 한국동물생명공학회지
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• 제36권2호
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• pp.116-120
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• 2021

Three different cats who had chronic kidney disease (CKD) were treated for more than one month with fluid therapy in an animal clinic. Although this long-term treatment and hospitalization, there was no clinical improvement in clinical signs as well as serum biochemical indexes including blood urea nitrogen (BUN), creatinine (CREA), and phosphate (PHOS). All cases were then injected three times with allogeneic stem cells through an intravenous route for treatment on Day 0, 7, and 14 or 30. On the same day, clinical observation and blood tests for serum biochemistry were conducted together. Upon administrating stem cells to the CKD cats, clinical conditions and the indexes of BUN and CREA were clinically improved within normal ranges. Additionally, one of the cats who had the renal cysts presented clinical improvement with showing decreased cysts size than before.

• Asian-Australasian Journal of Animal Sciences
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• 제33권4호
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• pp.568-578
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• 2020

Objective: The objective of this study was to investigate effects of supplementation of culture media from solid-state fermented Isaria cicadae (I. cicadae) on performance, serum biochemical parameters, serum immune indexes, antioxidant capacity and meat quality of broiler chickens. Methods: A total of 648 Arbor Acres male broiler chickens(1 d; average body weight, 42.93±0.47 g) were randomly assigned to 6 treatments, each with six replicates and 18 broiler chickens per replicate. Broiler chickens were fed phase I (d 1 to 21) and phase II (d 22 to 42) diets. The phase I diets were corn and soybean-meal based diets supplemented with 0%, 2%, 4%, 6%, 8%, or 10% culture media from solid-state fermented I. cicadae respectively. The phase II diets were corn and soybean-meal based diets supplemented with 0%, 1.33%, 2.67%, 4.00%, 5.32%, or 6.67% culture media from solid-state fermented I. cicadae respectively. Results: In phase I, the broiler chickens with the supplementation of culture media had increased body weight gain and feed intake (linear and quadratic, p<0.05) with increasing inclusion of culture media. The levels of serum total antioxidant capacity (T-AOC), glutathione (GSH) and superoxide dismutase (SOD) increased linearly (p<0.05). In phase II, levels of serum T-AOC and interleukin-1β increased linearly (p<0.05), and GSH increased (p<0.05). In the kidney, GSH and glutathione peroxidase (GSH-Px) concentrations increased (linear and quadratic, p<0.05) and SOD concentration increased linearly (p<0.05). Compared to the control, shear force and drip loss of breast muscle decreased (linear and quadratic, p<0.05). Drip loss of leg muscle decreased linearly and quadratically (p<0.05). Conclusion: Dietary supplementation of culture media from solid-state fermented I.cicadae which was enriched in both wheat and residual bioactive components of I. cicadae enhanced the growth performance of broiler chickens. It also improved body anti-oxidative status and contributed to improve broiler meat quality.

• The Korean Journal of Physiology and Pharmacology
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• 제20권6호
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• pp.565-571
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• 2016

Paeoniflorin (PAE) is the most abundant compound in Xuebijing injection widely used to treat sepsis. We aimed to investigate effect of PAE on expression of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in a rat model of sepsis. Wistar rats were divided into Normal, Model, and PAE groups (n=20 each). Endotoxin was administrated at 5 mg/ml/kg in Model and PAE rats to establish rat sepsis model. 1 h after endotoxin administration, PAE was administrated at 4 ml/kg in PAE group once per day for 3 days. Routine blood tests and biochemical indexes were assessed, including aspartate aminotransferase (AST) and creatine kinase-MB (CK-MB). The plasma sTREM-1 level was measured using quantitative ELISA. At the end of experiment, the small intestine, liver, kidney and lung were subjected to pathological examinations. A rat model of sepsis-induced multiple organ dysfunction syndrome (MODS) was established successfully with endotoxin administration (5 mg/ml/kg), evidenced by histo-pathological examinations, routine blood tests and biochemical indexes: platelet count decreased and white blood cell count increased (p<0.05), CK-MB and AST increased (p<0.05). PAE treatment significantly reduced the plasma levels of AST, CK-MB, and sTREM-1, compared to Model group (p<0.05). Meanwhile, sepsis-induced damages in the liver, lung, stomach and intestinal mucosa were also markedly ameliorated by PAE treatment. PAE demonstrated a significantly protective effect in a rat model of sepsis by decreasing plasma sTREM-1 level, reducing inflammation, preventing MODS and protecting organ functions.

• Fisheries and Aquatic Sciences
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• 제9권1호
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• pp.7-13
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• 2006

Using biochemical methods, we determined the potential of local female shrimp populations as breeding stock to select the best adult prawns for improving larval production. As condition indexes, we selected total RNA, DNA, their ratio, and trypsin activity. The DNA content in the pleopods of each local population was similar, i.e., between $0.90{\pm}0.06\;and\;1.02{\pm}0.04(SE){\mu}g/mg$. In comparison, the RNA contents differed markedly between $2.00{\pm}0.09$ and $0.96{\pm}0.08\;{\mu}g/mg$. Therefore, the RNA/DNA (R/D) ratio in the pleopod could be used as a condition index because it represents a biochemical characteristic of the population. The mean pleopodal R/D ratio of the Goheung population was the highest at $2.52{\pm}0.19$, which indicated the best condition. Trypsin activity was influenced little by shrimp condition and more by the amount of food ingested. The gonadosomatic index (GSI) and R/D ratio in the gonads provided offsetting information about the instantaneous gonad maturity. The Goheung population had the highest instantaneous GSI, despite some spawning. Based on the condition indexes and time of gonad maturation, the Goheung shrimp population is suitable for use as breeding stock.

• Korean Chemical Engineering Research
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• 제52권3호
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• pp.388-394
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• 2014

출발물질인 TTIP로부터 이산화티탄 졸을 합성하여 무기물로 사용하고 유기물로서 실란커플링제인 methacryloxypropyl trimethoxysilane (MPTMS), aminopropyl triethoxysilane (APS), glycidoxypropyl trimethoxysilane (GPTMS), vinyltriethoxysilane (VTES)을 2종 혹은 3종씩 복합 사용하여 유-무기 하이브리드 코팅 용액을 제조하였다. 그 후 코팅 용액을 기재인 PC시트 위에 스핀 코팅시키고, 열경화 시켜 하드코팅 막을 제조하였다. 2종 실란커플링제를 혼합하여 제조된 코팅 막들은 기재와의 부착력과 연필경도가 우수하지 못했으나, 3종 실란커플링제를 혼합하여 제조한 코팅 막은 2H~4H의 향상된 연필경도와 5B의 우수한 부착력을 나타내었다. 이산화티탄 졸의 첨가량이 20 g인 코팅 막의 굴절률은 550 nm에서 1.56을 나타내었으나 이산화티탄 졸의 첨가량을 20 g에서 30 g으로 증가시킨 경우, 코팅 막의 굴절률이 1.63으로 향상되었다.