• Title/Summary/Keyword: Bioanalysis

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Endocrine Disrupters

  • Lee Jung Ran;Choi Jeongeun;Jin Chang Bae;Choi Myung Ja
    • Proceedings of the Korean Society of Food Hygiene and Safety Conference
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    • 2001.10a
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    • pp.155-155
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    • 2001

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In vivo metabolism of 2-methylaminoethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2′-carboxy-2-carboxylate (DDB-S) in rats using deutrium labeled compound

  • Lee, Eun-Young;Shin, Myoung-Youp;Lee, Mi-Jin;Jung, Ha-Youn;Son, Jung-Hyun;Kim, Dong-Hyun
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.133.2-134
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    • 2003

  • 2-Methylaminoethyl-4, 4'-dimethoxy-5, 5', 6.6 -dimethylenedioxybiphenyl-2'-carboxy-2-carboxylate (DDB-S), a synthetic compound derived from DDB, has been known to protect liver against carbon tetrachloride-, D-galactosamine-, thioacetamide-, and prednisolone-induced hepatic injury in experimental animals. The metabolism of this compound has been assessed in rats by using liquid chromatography/electrospray tandem mass spectrometry (LC/MS/MS) method. (omitted)

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