• 제목/요약/키워드: BioInfomatics

검색결과 2건 처리시간 0.015초

은닉 마르코프 모델과 계층 정보를 이용한 개체명 경계 인식 (Named Entity Boundary Recognition Using Hidden Markov Model and Hierarchical Information)

  • 임희석
    • 한국산학기술학회논문지
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    • 제7권2호
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    • pp.182-187
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    • 2006
  • 본 논문은 통계 기반 접근 방식인 HMM(Hidden Markov model)과 생물학의 개체명에 관한 온톨로지 정보를 이용한 생물학 문서에서의 개체명(named entity) 경계 인식 방법을 제안한다. 제안하는 방법은 31개의 자질 정보를 이용한 평탄화 기법을 사용하며 생물학 개체명의 계층 정보를 이용하여 HMM의 자료 부족 문제를 완화시킬 수 있도록 하였다. 개체명 경계 인식의 학습과 실험을 위하여 GENIA 코퍼스 ver 2.1을 사용하였으며 개체명 경계 인식 실험을 수행한 결과 모든 부류를 사용한 경우보다 정확도 및 실행 속도가 개선됨을 확인하였다.

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Process Optimization of Nypa fruticans Wurmb Extract using Mixed Solvent and its Functional Component Analysis

  • Kim, Jin;Kim, Han Sung;Son, Jang Wan;Moon, Seong Yong;Lee, Sook-Young
    • 대한의생명과학회지
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    • 제28권1호
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    • pp.34-41
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    • 2022
  • In this study, conditions for extraction of functional component from Nypa fruticans wurmb was optimized. The yield by extraction with 30% ethanol (LE30, 42.12%) was higher than those hot water extraction (LDW 33.32%), 50% ethanol (LE50, 40.12%) and 70% ethanol (LE70, 34.5%). The extract was purified and analyzed by GC MS. The prevailing compounds found in extract were Cyclodecasiloxane-, pentadecanoic acid, -eicosane, undecanal and tridecanoic acid. The presence of saturated and unsaturated fatty acids in ethanolic extract vindicate the use of this plant to treat many diseases in traditional medicine. The total phenolic contents in the LDW, LE30, LE50, LE70 extract were 128±1.65 mg/g, 205±2.3 mg/g, 210±4.23 mg/g and 180±5.6 mg/g, respectively. The DPPH was highest in LE70 extract (1,000 ㎍/mL, 81.14%), ABTS was highest in LE50 extract (1,000 ㎍/mL, 84.14%). The protective effects against oxidative stress in raw 264.7 cell imparted by the LE50 extract was better than those imparted by the other extracts. The findings of the present study suggest that 50% ethanol is best solvent for extraction of Nypa fruticans Wurmb, considering yield, polyphenol content, and antioxidant activities with extraction cost.