• Title/Summary/Keyword: Bio-index

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Effects of the Soybean Powder with Rich Aglycone Isoflavone on Lipid Metabolism and Antioxidative Activities in Hyperlipidemic Rats (고지혈증 흰쥐에서 비배당체 이소플라본 고함유 대두분말의 혈청 지질 대사 영향과 항산화효과)

  • Lim, Ae-Kyoung;Jung, Hee-Kyoung;Hong, Joo-Heon;Oh, Jung-Suk;Kwak, Jung-Hoon;Kim, Yong-Hae;Kim, Dae-Ik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.3
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    • pp.302-308
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    • 2008
  • This study was performed to evaluate the effects of soybean powder with rich aglycone isoflavone through bio-transformation on lipid metabolism and antioxidative activites in diet induced hyperlipidemic rats. The rats were randomly divided into four groups: NO (basal diet normal group), CO (high fat diet control group), BFF10 (soybean powder with rich aglycone isoflavone 10% group), and BFF20 (soybean powder with rich aglycone isoflavone 20% group). After 7 weeks of BFF10 or BFF20 diets consumption, the concentrations in serum triglyceride, total cholesterol, LDL-cholesterol, and atherogenic index ratios were significantly decreased in the BFF10 and BFF20 diets groups compared with those in the CO group. The activities of alanine amino transferase and aspartate amino transferase were significantly decreased in the BFF10 and BFF20 than those in the CO group. Thiobarbituric acid reactive substance levels of serum were decreased in BFF10 and BFF20 groups compared to that of the CO group. The super oxide dismutase activites were increased in BFF10 and BFF20 groups compared to that of the CO group.

INVESTIGATION ON MECHANICAL AND BIO-MECHANICAL PERFORMANCE OF A CENTRIFUGAL BLOOD PUMP (혈액 펌프의 기계적 성능과 생체 역학적 성능에 대한 연구)

  • Chang, M.;Moshfeghi, M.;Hur, N.;Kang, S.;Kim, W.;Kang, S.H.
    • Journal of computational fluids engineering
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    • v.20 no.2
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    • pp.88-95
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    • 2015
  • Blood pump analysis process includes both mechanical and bio-mechanical aspects. Since a blood pump is a mechanical device, it has to be mechanically efficient. On the other hand, blood pumps function is sensitively related to the blood recirculation; hence, bio-factors such as hemolysis and thrombosis become important. This paper numerically investigates the mechanical and bio-mechanical performances of the Rotaflow in the extracorporeal membrane oxygenation(ECMO), Ventricular Assist Device(VAD), and full-load conditions. The operational conditions are defined as(400[mmHg], 5[L/min.]), (100[mmHg], 3[L/min.]), and (600[mmHg], 10[L/min.]) for ECMO, VAD, and full-load conditions, respectively. The results are presented and analyzed from the mechanical aspect via performance curves, and from bio-mechanical aspect via focusing on hemolytic characteristics. Regions of top and bottom cavities show recirculation in both ECMO and VAD condtions. In addition, Eulerian-based calculation of modified index of hemolysis(MIH) has been investigated. The results demonstrate that the VAD condition has the least risk of hemolysis among the others, while the full-load condition has the highest risk.

Risk Assessment for Heavy Metals in Soil, Ground Water, Rice Grain nearby Abandoned Mine Areas (국내 폐금속 광산지역에서의 토양, 지하수, 쌀의 중금속 노출에 따른 인체 위해성평가)

  • Na, Eun-Shik;Lee, Yong-Jae;Ko, Kwang-Yong;Chung, Doug-Young;Lee, Kyu-Seung
    • Korean Journal of Environmental Agriculture
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    • v.32 no.4
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    • pp.245-251
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    • 2013
  • BACKGROUND: The objectives of this study are to investigate the contamination levels of heavy metals in soil, ground water, and agricultural product near the abandoned Boeun and Sanggok mine areas in Korea and to assess the health risk for these local residents exposed to the toxic heavy metals based on analytical data. METHODS AND RESULTS: By the results of human health risk assessment for local residents around Boeun and Sanggok, human exposure to cadmium, copper, arsenic from soil and to lead, cadmium, and arsenic from rice grain were higher in Sanggok, but human exposure to zinc and arsenic from ground water was higher in Boeun. By the results of hazard index (HI) evaluation for arsenic, cadmium, copper, lead, and zinc, HI values in both areas were higher than 1.0. This result indicated that the toxicity hazard through the continuous exposure to lead, cadmium, arsenic from rice, ground water, and soil would be likely to occur to the residents in the areas. Cancer risk assessment for arsenic, risks from the rice were exposed to one to two out of 10,000 people in Boeun and one of 1,000 people in Sanggok. These results showed that the cancer risks of arsenic in both areas were 10~100 times greater than the acceptable cancer risk range of US EPA ($1{\times}10^{-6}{\sim}1{\times}10^{-5}$). CONCLUSION(S): Therefore, if these two local residents consume continuously with arsenic contaminated soil, ground water, and rice, the adverse health effects (carcinogenic potential) would be more increased.

Production of liquid fertilizer from broken eggs and evaluation of its effect on lettuce growth

  • Kim, Bo-Ra;Lee, Jae-Han;Kim, Su-Hun;Choi, Ha-Yeon;Choi, Bong-Su;Oh, Taek-Keun;Lee, Chang-Hoon
    • Korean Journal of Agricultural Science
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    • v.47 no.1
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    • pp.11-18
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    • 2020
  • Eggs are likely to be used in agriculture because they can provide enough nutrients for crop growth. Statistics show that a large number of eggs are lost due to breakage before reaching the final consumer. The purpose of this study was to make a natural liquid fertilizer as a substitute for chemical fertilizers using broken eggs as a resource and to evaluate the efficiency of the formulated fertilizer. To make the liquid fertilizer, the broken eggs and distilled water were mixed at ratios of 6 : 4 and 4 : 6. Then, effective micro-organisms (EM) and sugar were added, and the mixture was fermented. The temperature and electrical conductivity (EC) increased gradually with the fermentation while the pH decreased. When evaluated following the seed germination index method of the compost, it was found that the fertilizer matured 10 days after the beginning of the experiment. The growth experiment was conducted with lettuce in which the fermented liquid fertilizer was compared with a commercial liquid fertilizer. The 6 : 4 treatment produced plants with the densest fresh shoot and roots weighing 41.6 and 4.6 g, respectively. The number of leaves (12.3 per plant) was also the highest for the 6 : 4 treatment. Soil analysis showed that the soil pH was improved, and the soil organic matter was increased in the fermented liquid fertilizer treatment.

Estimation of TOC Concentration using BOD, COD in Runoff from Paddy Fields (영농기간동안 논 유출수 BOD, COD 자료를 이용한 TOC 농도 추정)

  • Choi, Dongho;Jung, Jaewoon;Yoon, Kwangsik;Lee, Kyoungsook;Choi, Woojung;Lim, Sangsun;Park, Hana;Yim, Byungjin;Hwang, Taehee
    • Journal of Korean Society on Water Environment
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    • v.28 no.6
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    • pp.813-818
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    • 2012
  • BOD and COD are currently used for water quality indices, but adoption of TOC for TMDL (Total Maximum Daily Load) is being suggested. Estimation of TOC using existing BOD and COD data is very important to diagnosis water quality trend when TOC is used for water quality index of organic matter in the future. The relationships between BOD COD and TOC in runoff from paddy fields were investigated during 2008-2011. The observed mean concentration of EMCs (Event Mean Concentration) for BOD, COD, TOC were 3.87, 10.97, 7.26 mg/L respectively. The correlation coefficients between BOD-TOC and COD-TOC were 0.42, 0.73, respectively. The coefficient of determination of regression equation for BOD-TOC and COD-TOC were 0.18, 0.53 respectively. Even though, conversion of COD data to TOC seems to be rather reliable than that of BOD-TOC, further monitoring is recommended to ensure better interpretation of relationship among BOD, COD and TOC.

Development of Agricultural Drought Assessment Approach Using SMAP Soil Moisture Footprints (SMAP 토양수분 이미지를 이용한 농업가뭄 평가 기법 개발)

  • Shin, Yongchul;Lee, Taehwa;Kim, Sangwoo;Lee, Hyun-Woo;Choi, Kyung-Sook;Kim, Jonggun;Lee, Giha
    • Journal of The Korean Society of Agricultural Engineers
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    • v.59 no.1
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    • pp.57-70
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    • 2017
  • In this study, we evaluated daily root zone soil moisture dynamics and agricultural drought using a near-surface soil moisture data assimilation scheme with Soil Moisture Active & Passive (SMAP, $3km{\times}3km$) soil moisture footprints under different hydro-climate conditions. Satellite-based LANDSAT and MODIS image footprints were converted to spatially-distributed soil moisture estimates based on the regression model, and the converted soil moisture distributions were used for assessing uncertainties and applicability of SMAP data at fields. In order to overcome drawbacks of the discontinuity of SMAP data at the spatio-temporal scales, the data assimilation was applied to SMAP for estimating daily soil moisture dynamics at the spatial domain. Then, daily soil moisture values were used to estimate weekly agricultural drought based on the Soil Moisture Deficit Index (SMDI). The Yongdam-dam and Soyan river-dam watersheds were selected for validating our proposed approach. As a results, the MODIS/SMAP soil moisture values were relatively overestimated compared to those of the TDR-based measurements and LANDSAT data. When we applied the data assimilation scheme to SMAP, uncertainties were highly reduced compared to the TDR measurements. The estimated daily root zone soil moisture dynamics and agricultural drought from SMAP showed the variability at the sptio-temporal scales indicating that soil moisture values are influenced by not only the precipitation, but also the land surface characteristics. These findings can be useful for establishing efficient water management plans in hydrology and agricultural drought.

Dynamics of Microalgae Along the Coastal Areas of Sooyoung Bay, Busan, South Korea

  • Prasad, Binod;Thiyam, General;Lee, Dong-Gyu;Kim, Moo-Sang;Cho, Man-Gi
    • Journal of Marine Bioscience and Biotechnology
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    • v.5 no.4
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    • pp.40-45
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    • 2011
  • Microalgae are one of the major, sustaining components of ecosystem processes and are responsible for biogeochemical reactions that drive our climate changes. Despite this, many marine microalgae are poorly described and little is known of their abundance and distribution along the coastal areas of Sooyoung Bay, Busan, South Korea. The present study has been conducted from November, 2011 to August, 2009 with the objective to provide an overview of the taxonomy diversity and abundance of microalgae along the coastal areas of the Sooyoung Bay. Water samples were collected from different sites, which were located by using a GPS tracker. Chlorophyll fluorescence of the water samples were measured by using ToxY-PAM dual-channel yield analyzer. The chlorophyll fluorescence values were relatively higher during the spring and summer and even in the region near to the sea port. Similarly the abundance of microalgae was higher near the port but diversity index had lower values. The temperature and pH values were same at all the sites. However, only the temperature varied during the sampling period, with higher values during summer and lower in winter. From the preliminary results, the following class of microalgae were found; Bacillariophyceae, Dinophyceae, Silicoflagellate and Cryptophyceae. With a future ongoing work, microalgae are being isolated to establish single cell culture and for identification using light microscopic observations, photography and molecular approaches.

Antimicrobial, Anti-inflammatory, and Anti-oxidative Activities of Scilla scilloides (Lindl.) Druce Root Extract

  • Yeo, Eun-Ju;Kim, Kee-Tae;Han, Ye-Sun;Nah, Seung-Yeol;Paik, Hyun-Dong
    • Food Science and Biotechnology
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    • v.15 no.4
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    • pp.639-642
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    • 2006
  • The root extract of Scilla scilloides (which has been used as a traditional folk medicine in Korea) was evaluated with regard to antimicrobial, anti-inflammatory, and anti-oxidative activities. The roots of S. scilloides were minced and extracted with 95% ethanol (root:ethanol=25:75, w/v). The inhibitory effects of S. scilloides root extract on the growth of Staphylococcus aureus ATCC 35556, Salmonella enteritidis ATCC 12021, Escherichia coli O157:H7, and Candida parapsilosis KCCM 35428 were tested. The results indicate that the antimicrobial effects of both 0.1 and 1.0% extract of S. scilloides were greater against the growth of S. aureus ATCC 35556 and C. parapsilosis KCCM 35428 than the growth of S. enteritidis ATCC 12021 and E. coli O157:H7. The anti-inflammatory effects were evaluated by measurement of the inhibition of hyaluronidase activity in vitro. It appears that both 0.1 and 1.0% concentrations of extract have inhibitory effects on hyaluronidase relative to the control. Finally, the anti-oxidative effect of 1.0 and 10% extract solutions were measured according to the thiocyanate method and were compared with 1.0% BHT. The results indicate that the anti-oxidative effect of 10% S. scilloides root extract (anti-oxidative index (AOI); $72.3{\pm}4.2$) is not significantly different from that of 1.0% BHA (AOI; $76.8{\pm}3.5$) (p<0.05). However, it appears that the anti-oxidative effect of S. scilloides root extract is at least three-fold greater than that of BHA when accounting for the amount of dissolved solids in each.

Effect of Cheonggukjang Pills Product Containing Blueberry and Aronia in Mouse Inflammatory Bowel Disease (블루베리와 아로니아를 함유한 청국장 환 제품의 마우스 염증성 장질환 개선 효과)

  • Ha-Rim, Kim;Eun-Mi, Noh;Seung-Hyeon, Lee;Jong Hyun, Cho;Mi Hee, Park;Seon-Young, Kim
    • The Korean Journal of Food And Nutrition
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    • v.35 no.6
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    • pp.513-520
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    • 2022
  • The purpose of this study was to investigate the effect of Cheonggukjang pills with aronia and blueberries on dextran sulfate sodium (DSS)-induced colitis in mice. There have been several reports that Cheonggukjang is effective for intestinal health, but the efficacy of Cheonggukjang containing fruits has not yet been reported. In this study, we showed the effect of cheonggukjang pills with blueberries and aronia (CPBA) on DSS-induced colitis in BALB/c mice. CPBA was obtained from Soonchang Moonokae foods and orally administered once a day for 2 weeks before DSS treatment. Colitis was induced in mice by feeding 5% (w/v) DSS drinking water for 7 days. The results showed that CPBA treatment significantly alleviated DSS-induced disease activity index associated with a decrease in colon length. CPBA improved DSS-induced histological changes and intestinal epithelial barrier integrity in mice colon. In addition, CPBA administration significantly reduced the levels of DSS-mediated interferon-γ and interleukin-6 in serum and tumor necrosis factor-α in colon tissue. Moreover, the gene expression of COX-2 and iNOS, which are factors involved in inflammatory signaling, was significantly reduced by CPBA treatment. These results suggest that CPBA have a protective effect against DSS-induced mice colitis and may be a candidate for colitis treatment.

Effects of various cooling methods and drinking water temperatures on reproductive performance and behavior in heat stressed sows

  • Habeeb, Tajudeen;Joseph, Moturi;Abdolreza, Hosseindoust;SangHun, Ha;Jun Young, Mun;YoHan, Choi;SooJin, Sa;JinSoo, Kim
    • Journal of Animal Science and Technology
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    • v.64 no.4
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    • pp.782-791
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    • 2022
  • The purpose of this study is to evaluate the effects of multiple cooling systems and different drinking water temperatures (DWT) on the performance of sows and their hair cortisol levels during heat stress. In this study, the effect of four different cooling systems: air conditioner (AC), cooling pad (CP), snout cooling (SC), and mist spray (MS), and two DWT, namely low water temperature (LWT) and high water temperature (HWT) on 48 multiparous sows (Landrace × Yorkshire; 242.84 ± 2.89 kg) was tested. The experiment is based on the use of eight replicas during a 21-days test. Different behaviors were recorded under different cooling treatments in sows. As a result, behaviors such as drinking, standing, and position change were found to be lower in sows under the AC and CP treatments than in those under the SC and MS treatments. Lying behavior increased under the AC and CP systems as compared with that under the SC and MS, systems. The average daily feed intake (ADFI) in sows and weight at weaning in piglets was higher under the AC, CP, and LWT treatments than under the SC, MS and HWT treatments. Sows subjected to SC and MS treatment showed higher hair cortisol levels, rectal temperature, and respiratory rate during lactation than those under AC and CP treatments. Hair cortisol levels, rectal temperature, and respiratory rate were also higher under the HWT than under the LWT treatment. As per the results of this study, the LWT has no significant effect on any of the behavioral factors. Taken together, the use of AC and CP cooling treatment is highly recommended to improve the behavior and to reduce the stress levels in lactating sows.