• Title/Summary/Keyword: Bio-assessment

Search Result 462, Processing Time 0.026 seconds

Evaluation of Suitable Locations of Green Care Farm Complex According to Spatial Scale (공간규모별 치유농업단지 입지잠재력 평가)

  • Lim, Hye-Ji;Bae, Seung-Jong;Koo, Hee-Dong;Kim, Dae-Sik
    • Journal of Korean Society of Rural Planning
    • /
    • v.27 no.3
    • /
    • pp.93-102
    • /
    • 2021
  • This study was attempted to provide a scientific basis for the problem of location selection by spatial scale for efficient promotion of projects related to green care farm complex. Location potential assessment system in local government scale consists of two major components from demand-side and supply-side consideration. The demand-side aspect considered the characteristics of potential users, while supply-side aspect used total 18 indices over 8 divisions under 3 fields. For the location potential assessment in district scale, total 8 indices under 3 major divisions were considered based on biological, physical, social, and economic environment. The application results of the location potential evaluation system in local government scale(excluding metropolitan cities) showed high location potential in southern Gyeonggi Province and near Busan Metropolitan City. As a result of applying the district-scale location potential evaluation system to Geumsan-gun, Geumsan-eup, Chubu-myeon, and Jewon-myeon have high potential. Further studies to improve the applicability of the developed indices are recommended by enhancing assessment indices, complementing base data, and reinforcing with spatial analysis.

A new proposal for controlled recycling of decommissioning concrete waste as part of engineered barriers of a radioactive waste repository and related comprehensive safety assessment

  • In Gyu Chang;Jae Hak Cheong
    • Nuclear Engineering and Technology
    • /
    • v.55 no.2
    • /
    • pp.530-545
    • /
    • 2023
  • As an alternative to conventional management options for a lot of concrete waste from decommissioning of nuclear power plants, a set of scenarios for controlled recycling of decommissioning concrete waste as engineered barriers of a radioactive waste repository was proposed, and a comprehensive safety assessment model and framework covering both pre-and post-closure phases was newly developed. The new methodology was applied to a reference vault-type repository, and the ratios of derived concentration limits to unconditional clearance levels of eighteen radionuclides for controlled recycling were provided for three sets of dose criteria (0.01, 1, and 20 mSv/y for the pre-closure and 0.01 mSv/y for the post-closure phases). It turns out that decommissioning concrete waste whose concentration is much higher than the unconditional clearance level can be recycled even when the dose criterion 0.01 mSv/y is applied. Moreover, a case study on ABWR bio-shield shows that the fraction of recyclable concrete waste increases significantly by increasing the dose criterion for the radiation worker in the pre-closure phase or the duration of storage prior to recycling. The results of this study are expected to contribute to demonstrating the feasibility of controlled recycling of a lot of decommissioning concrete waste within nuclear sectors.

Quantitative Assessment of the Relative Antineoplastic Potential of the n-butanolic Leaf Extract of Annona Muricata Linn. in Normal and immortalized Human Cell Lines

  • George, V. Cijo;Kumar, D.R. Naveen;Rajkumar, V.;Suresh, P.K.;Kumar, R. Ashok
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.2
    • /
    • pp.699-704
    • /
    • 2012
  • Natural products have been the target for cancer therapy for several years but there is still a dearth of information on potent compounds that may protect normal cells and selectively destroy cancerous cells. The present study was aimed to evaluate the cytotoxic potential of n-butanolic leaf extract of $Annona$ $muricata$ L. on WRL-68 (normal human hepatic cells), MDA-MB-435S (human breast carcinoma cells) and HaCaT (human immortalized keratinocyte cells) lines by XTT assay. Prior to cytotoxicity testing, the extract was subjected to phytochemical screening for detecting the presence of compounds with therapeutic potential. Their relative antioxidant properties were evaluated using the reducing power and $DPPH^*$radical scavenging assay. Since most of the observed chemo-preventive potential invariably correlated with the amount of total phenolics present in the extract, their levels were quantified and identified by HPLC analysis. Correlation studies indicated a strong and significant (P<0.05) positive correlation of phenolic compounds with free radical scavenging potential. The results revealed that the extract was moderately cytotoxic to normal cells with a mean IC50 value of 52.4 ${\mu}g$ when compared with those obtained for cancerous cells (IC50 values of 29.2 ${\mu}g$ for MDA-MB-435S and 30.1 ${\mu}g$ for HaCaT respectively). The study confirms the presence of therapeutically active antineoplastic compounds in the n-butanolic leaf extract of $Annona$ $muricata$. Isolation of the active metabolites from the extract is in prospect.

A Study on the Resilient Supply of Agricultural Water in Jeju Island by Forecasting Future Demand (미래 수요예측을 통한 제주도 농업용수 회복탄력적 공급 방안에 관한 연구)

  • Go, Jea-han;Jeung, Minhyuk;Beom, Jina;Sung, Mu-hong;Jung, Hyoung-mo;Yoo, Seung-hwan;Yoon, Kwang-sik
    • Journal of The Korean Society of Agricultural Engineers
    • /
    • v.62 no.3
    • /
    • pp.71-83
    • /
    • 2020
  • Resilience is the capacity to maintain essential services under a range of circumstances from normal to extreme. It is achieved through the ability of assets, networks, systems and management to anticipate, absorb and recover from disturbance. It requires adaptive capacity in respect of current and future risks and uncertainties as well as experience to date. The agricultural infrastructures with high resilience can not only reduce the size of the disaster relatively, but also minimize the loss by reducing the time required for recovery. This study aims to evaluate the most suitable drought countermeasures with the analysis of various resilience indices by predicting future agricultural water shortage under land use and climate change scenarios for agricultural areas in Jeju Island. The results showed that the permanent countermeasure is suitable than the temporary countermeasures as drought size and the cost required for recovery increase. Wide-area water supply system, which is a kind of water grid system, is identified as the most advantageous among countermeasures. It is recommended to evaluate the capability of agricultural infrastructure against drought with the various Resilience Indices for reliable assessment of long-term effect.

Design and Implementation of Smart Healthcare Monitoring System Using Bio-Signals (생체 신호를 이용한 스마트 헬스케어 모니터링 시스템 설계 및 구현)

  • Yoo, So-Wol;Bae, Sang-Hyun
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
    • /
    • v.10 no.5
    • /
    • pp.417-423
    • /
    • 2017
  • This paper intend to implement monitoring systems for individual customized diagnostics to maintain ongoing disease management to promote human health. Analyze the threshold of a measured biological signal using a number of measuring sensors. Performance assessment revealed that the SVM algorithm for bio-signal analysis showed an average error rate of 2 %. The accuracy of the classification is 97.2%, and reduced the maximum of 19.2% of the storage space when you split the window into 5,000 pieces. Out of the total 5,000 bio-signals, 84 results showed that results from the system were differently the results of the expert's diagnosis and showed about 98 % accuracy. However, the results of the monitoring system did not occur when the results of the monitoring system were lower than that of experts. And About 98% accuracy was shown.

Effect of Co-inoculation of Two Bacteria on Phosphate Solubilization

  • Lee, Yu-Jin;Lee, Heon-Hwak;Lee, Chan-Jung;Yoon, Min-Ho
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.49 no.4
    • /
    • pp.318-326
    • /
    • 2016
  • Two phosphate solubilizing bacteria, Pantoea rodasii PSB-11and Enterobacter aerogenes PSB-12, were isolated from button mushroom compost and employed to assess their synergistic effect in liquid medium and on growth of green gram plants by single and co-inoculation of the strains. Co-inoculation of two strains was found to release the highest content of soluble phosphorus ($521{\mu}g\;ml^{-1}$) into the medium, followed by single inoculation of Pantoea strain ($485{\mu}g\;ml^{-1}$) and Enterobacter strain ($470{\mu}g\;ml^{-1}$). However, there was no significant difference between single inoculation of bacterial strain and co-inoculation of two bacterial strains in terms of phosphorous release. The highest pH reduction, organic acid production and glucose consumption was observed in the E. aerogenes PSB-12 single inoculated culture medium rather than those of co-inoculation. According to the plant growth promotion bioassay, co-inoculated mung bean seedlings recorded 10.6% and 10.7% higher shoot and root growth respectively compared to the control. Therefore, in concluding, co-inoculation of the strains P. rodasii and E. aerogenes displayed better performance in stimulating plant growth than inoculation of each strain alone. However, being short assessment period of the present study, we recommend in engaging further works under field conditions in order to test the suitability of the strains to be used as bio-inoculants.

Changes in Biston robustum and Camellia japonica distributions, according to climate change predictions in South Korea

  • Kim, Tae Guen;Han, Yong-Gu;Jeong, Jong Chul;Kim, Youngjin;Kwon, Ohseok;Cho, Youngho
    • Journal of Ecology and Environment
    • /
    • v.38 no.3
    • /
    • pp.327-334
    • /
    • 2015
  • We investigated the current and potential spatial distributions and habitable areas of Biston robustum and Camellia japonica in South Korea in order to provide useful data for the conservation of C. japonica and minimize the damage caused by B. robustum. It was predicted that, by 2070, although B. robustum would be widely distributed throughout the Korean Peninsula, except for the western and eastern coastal areas, it would be narrowly distributed along the Sokcho-si and Goseong-gun coastlines in Gangwon Province. C. japonica is currently located along the southern coastline but its critical habitable area is predicted to gradually disappear by 2070. Assessment of the potential distribution probabilities of B. robustum and C. japonica revealed that the area under the curve (AUC) values were 0.995 and 0.991, respectively, which indicate high precision and applicability of the model. Major factors influencing the potential distribution of B. robustum included precipitation of wettest quarter and annual precipitation (BIO16 and BIO12), whereas annual mean temperature and mean temperature of wettest quarter (BIO1 and BIO8) were important variables for explaining C. japonica distribution. Overlapping areas of B. robustum and C. japonica were $11,782km^2$, $5447km^2$, and $870km^2$ for the current, 2050-predicted, and 2070-predicted conditions, respectively, clearly showing a dramatic decrease in area. Although it is predicted that B. robustum would cause continuous damage to C. japonica in the southern part of the Korean Peninsula, such impacts might diminish over time and become negligible in the future.

A Study on the Development of Oxygen Cluster Ion Generator for Sterilization of Bio Clean Room(BCR) (Bio Clean Room(BCR)의 멸균을 위한 산소 클러스터이온 발생 장치 개발에 관한 연구)

  • Park, Dong-Il;Chung, Kwang-Seop;Kim, Young-Il;Kim, Sung-Min
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
    • /
    • v.25 no.1
    • /
    • pp.7-13
    • /
    • 2013
  • Bio Clean Room(BCR) and pharmaceutical product manufacturing facilities require careful assessment of many factors, including HVAC, controls, room finishes, process equipment, room operations, and utilities. Flow of equipment, personnel, and product must also be considered along with system flexibility, redundancy, and maintenance shutdown strategies. It is important to involve designers, operators, commissioning staff, quality control, maintenance, constructors, validation personnel, and the production representative during the conceptual stage of design. Critical variables for room environment and types of controls vary greatly with the clean space's intended purpose. It is particularly important to determine critical parameters with quality assurance to set limits and safety factors for temperature, humidity, room pressure, and other control requirements. In this paper, oxygen cluster ion equipment was utilized in order to enhance the indoor air quality and to prevent the airborne infection of ward in hospital. Moreover, the performance test of the equipment was also performed in order to develop the optimal sterilization system of BCR using the equipment.

Toxicity Assessment and Evaluation of the Applicability of a Constructed Wetland of Bio-reeds and Bio-ceramics (바이오갈대와 바이오여재를 적용한 인공습지의 효율성 및 독성평가)

  • Park, Da Kyung;Chang, Soon-Woong;Choi, Hanna
    • Korean Journal of Environmental Biology
    • /
    • v.35 no.4
    • /
    • pp.654-661
    • /
    • 2017
  • Recently, a low-impact development (LID) technic such as a wetland has been proposed as a Nature-friendly process for reducing pollutants caused by livestock wastewater. Therefore, the Daphnia magna toxicity was analyzed for livestock wastewater samples, to determine if a wetland system would also be effective in reducing this ecotoxicity. In the present study, acute D. magna toxicity was not significantly dependent on the presence and type of reed, nor type of media. However, when treated with construction wetlands, ecotoxicities decreased as well as TN, TP and COD concentrations. Therefore, it is considered that a construction wetland system with bio reeds and bio-media as well as general reeds would be effective to reduce the ecotoxicity of livestock wastewater. To apply a wetland system as the subsequent treatment process to a livestock waste water treatment facility, it is necessary to perform an integrated evaluation such as treatment efficiency and the ecotoxicity test for various characteristics of livestock wastewater.

Autumn olive (Elaeagnus umbellata Thunb.) berry reduces fasting and postprandial glucose levels in mice

  • Kim, Jung-In;Baek, Hee-Jin;Han, Do-Won;Yun, Jeong-A
    • Nutrition Research and Practice
    • /
    • v.13 no.1
    • /
    • pp.11-16
    • /
    • 2019
  • BACKGROUND/OBJECTIVES: Fasting and postprandial hyperglycemia should be controlled to avoid complications of diabetes mellitus. This study investigated the effects of autumn olive (Elaeagnus umbellata Thunb.) berry (AOB) on fasting and postprandial hyperglycemia in mice. MATERIALS/METHODS: In vitro ${\alpha}$-glucosidase inhibitory effect of AOB was determined. Maltose solution (2 g/kg) with and without AOB extract at 500 mg/kg or acarbose at 50 mg/kg was orally administered to normal mice after overnight fasting and glucose levels were measured. To study the effects of chronic consumption of AOB, db/db mice received the basal diet or a diet containing AOB extract at 0.4% or 0.8%, or acarbose at 0.04% for 7 weeks. Blood glycated hemoglobin and serum glucose and insulin levels were measured. Expression of adiponectin protein in epididymal white adipose tissue was determined by Western blotting. RESULTS: In vitro inhibitory effect of AOB extract on ${\alpha}$-glucosidase was 92% as strong as that of acarbose. The AOB extract (500 mg/kg) or acarbose (50 mg/kg) significantly suppressed the postprandial rise of blood glucose after maltose challenge and the area under the glycemic response curve in normal mice. The AOB extract at 0.4% or 0.8% of diet or acarbose at 0.04% of diet significantly lowered levels of serum glucose and blood glycated hemoglobin and homeostasis model assessment for insulin resistance values in db/db mice. The expression of adiponectin protein in adipose tissue was significantly elevated by the consumption of AOB at 0.8% of diet. CONCLUSIONS: Autumn olive (E. umbellata Thunb.) berry may reduce postprandial hyperglycemia by inhibiting ${\alpha}$-glucosidase in normal mice. Chronic consumption of AOB may alleviate fasting hyperglycemia in db/db mice partly by inhibiting ${\alpha}$-glucosidase and upregulating adiponectin expression.