• 제목/요약/키워드: Bio-analysis

검색결과 3,811건 처리시간 0.027초

결합된 플라즈몬-도파관 공진 구조로 구성된 바이오센서의 구현 (Implementation of Bio-Sensor with Coupled Plasmon-Waveguide Resonance Profile)

  • 호광춘
    • 한국인터넷방송통신학회논문지
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    • 제24권1호
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    • pp.109-114
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    • 2024
  • 결합된 플라즈몬-도파관 공진 (PWR) 구조에서 전파하는 TE, TM 전송 모드들의 바이오 센싱 특성을 조사하였다. 수치해석을 위하여 모드 전송선로 이론 (MTLT)을 사용되었다. 기존의 Ag-기반 표면 플라즈몬 공명 바이오센서의 감도를 향상시키기 위하여, 제안된 PWR 바이오센서는 N쌍의 MgF2-Si3N4 층으로 구성된 다층구조로 설계하였다. 그 바이오센서의 각도 감도가 광범위한 생물학적 용액 (굴절률 1.33~1.37)에 대하여 수치적으로 분석되었다. 더욱이, 암세포와 혈장 농도를 감지하는 센서의 가용성을 조사하였다. 결국, 그 결과들은 제안된 바이오센서가 소변에서 다양한 종류의 암 세포와 다양한 포도당 농도를 효율적으로 감지할 수 있음을 보여주었다.

Quantitative analysis of glycerol concentration in red wine using Fourier transform infrared spectroscopy and chemometrics analysis

  • Joshi, Rahul;Joshi, Ritu;Amanah, Hanim Zuhrotul;Faqeerzada, Mohammad Akbar;Jayapal, Praveen Kumar;Kim, Geonwoo;Baek, Insuck;Park, Eun-Sung;Masithoh, Rudiati Evi;Cho, Byoung-Kwan
    • 농업과학연구
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    • 제48권2호
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    • pp.299-310
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    • 2021
  • Glycerol is a non-volatile compound with no aromatic properties that contributes significantly to the quality of wine by providing sweetness and richness of taste. In addition, it is also the third most significant byproduct of alcoholic fermentation in terms of quantity after ethanol and carbon dioxide. In this study, Fourier transform infrared (FT-IR) spectroscopy was employed as a fast non-destructive method in conjugation with multivariate regression analysis to build a model for the quantitative analysis of glycerol concentration in wine samples. The samples were prepared by using three varieties of red wine samples (i.e., Shiraz, Merlot, and Barbaresco) that were adulterated with glycerol in concentration ranges from 0.1 to 15% (v·v-1), and subjected to analysis together with pure wine samples. A net analyte signal (NAS)-based methodology, called hybrid linear analysis in the literature (HLA/GO), was applied for predicting glycerol concentrations in the collected FT-IR spectral data. Calibration and validation sets were designed to evaluate the performance of the multivariate method. The obtained results exhibited a high coefficient of determination (R2) of 0.987 and a low root mean square error (RMSE) of 0.563% for the calibration set, and a R2 of 0.984 and a RMSE of 0.626% for the validation set. Further, the model was validated in terms of sensitivity, selectivity, and limits of detection and quantification, and the results confirmed that this model can be used in most applications, as well as for quality assurance.

Microfluidic Components and Bio-reactors for Miniaturized Bio-chip Applications

  • Euisik Yoon;Yun, Kwang-Seok
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제9권2호
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    • pp.86-92
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    • 2004
  • In this paper miniaturized disposable micro/nanofluidic components applicable to bio chip, chemical analyzer and biomedical monitoring system, such as blood analysis, micro dosing system and cell experiment, etc are reported. This system includes various microfluidic components including a micropump, micromixer, DNA purification chip and single-cell assay chip. For low voltage and low power operation, a surface tension-driven micropump is presented, as well as a micromixer, which was implemented using MEMS technology, for efficient liquid mixing is also introduced. As bio-reactors, DNA purification and single-cell assay devices, for the extraction of pure DNA from liquid mixture or blood and for cellular engineering or high-throughput screening, respectively, are presented.

Isolation of Protease-Producing Arctic Marine Bacteria

  • Lee, Yoo-Kyung;Sung, Ki-Cheol;Yim, Joung-Han;Park, Kyu-Jin;Chung, Ho-Sung;Lee, Hong-Kum
    • Ocean and Polar Research
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    • 제27권2호
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    • pp.215-219
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    • 2005
  • We isolated and identified three protease-producing bacteria that had inhabited the region around the Korean Arctic Research Station Dasan located at Ny-Alesund, Svalbard, Norway $(79^{\circ}N,\;12^{\circ}E)$. Biofilms were collected from the surface of a floating pier and from dead brown algae in a tide pool near the seashore. The biofilm samples were transported to the Korea Polar Research Institute (KOPRI) under frozen conditions, diluted in sterilized seawater, and cultured on Zobell agar plates with 1% skim milk at $10^{\circ}C$. Three clear zone forming colonies were selected as protease-producing bacteria. Phylogenetic analysis based on 16S rDNA sequences showed that these three stains shared high sequence similarities with Pseudoalteromonas elyakovii, Exiguobacterium oxidotofewm Pseudomonas jessenii, respectively. We expect these Arctic bacteria may be used to develop new varieties of protease that are active at low temperatures.

First Report of Mortierella alpina (Mortierellaceae, Zygomycota) Isolated from Crop Field Soil in Korea

  • Yadav, Dil Raj;Kim, Sang Woo;Babu, Anam Giridhar;Adhikari, Mahesh;Kim, Changmu;Lee, Hyang Burm;Lee, Youn Su
    • Mycobiology
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    • 제42권4호
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    • pp.401-404
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    • 2014
  • A new recorded species of Mortierella was recovered during the investigation of fungal communities in soil samples collected from different locations of Gangwon-do, Korea. The species was identified and described as Mortierella alpina on the basis of phylogenetic analysis of internal transcribed spacer sequences and morphological characteristics. This species has not been officially reported from Korea thus far.

생물 환경 조절 시스템에 대한 객체 지향적 분석 (Object-Oriented Analysis for Bio-Environmental Control System)

  • 강석원
    • 한국생물환경조절학회:학술대회논문집
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    • 한국생물환경조절학회 2002년도 추계 심포지엄 및 학술발표 논문집
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    • pp.279-284
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    • 2002
  • 생물생산에 따른 생산시설 및 환경조절에 대한 생물 환경 조절 시스템은 식물이나 동물과 같은 생물을 보호하기 위한 간단한 구조물에서 환경조절, 생물의 성장, 그리고 공간과 노동력의 이용 둥이 효율적으로 상호 작용하는 복잡하며 정교한 시스템도 있다. 이 시스템이 어떠한 형태로 구성되어있더라도, 가장 중요한 목표는 시스템이 이루고자 하는 목적을 달성하고, 경제적인 이윤을 남기고 또한 경제적으로 살아남을 수 있는가에 있다. (중략)

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