• Journal of Dental Anesthesia and Pain Medicine
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• v.20 no.4
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• pp.213-221
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• 2020

Background: Complications following impacted third molar surgery significantly affect patients' quality of life during the immediate postoperative period. This study aimed to achieve the proper anesthesia method by comparing the effect of the application of lidocaine alone with the application of lidocaine and articaine simultaneously in reducing the complications during and following impacted mandibular third molar surgery. Methods: The study design was a split-mouth double-blind randomized clinical trial. The study was conducted on 13 patients (26 samples) referred for elective surgical removal of bilateral impacted mandibular third molar with similar difficulty on both sides. Each patient underwent similar surgical procedures on two separate appointments. Each patient randomly received 2% lidocaine for conventional inferior alveolar nerve block and 4% articaine for local infiltration before the surgery on one side (group A) and 2% lidocaine alone (for both block anesthesia and infiltration) before the surgery on the other side (group B). Intraoperative and postoperative variables for both groups were established and statistically analyzed. Results: The findings showed that pain on the first day after surgery in group A was significantly lower than that in group B. The patients in group A mentioned experiencing less discomfort following the surgery. The increased horizontal swelling on the first and third days following surgery and oblique swelling on the seventh day in patients in group B were statistically significant. Conclusion: Choosing an appropriate anesthetic drug for oral surgery, specifically impacted third molar surgery, is dependent on the clinician's opinion, however; it seems that the combination of lidocaine and articaine may control the patient's pain significantly better than lidocaine alone.

• The korean journal of orthodontics
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• v.47 no.4
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• pp.256-267
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• 2017

Objective: To evaluate transverse skeletal and dental changes, including those in the buccolingual dental axis, between patients with skeletal Class III malocclusion and facial asymmetry after bilateral intraoral vertical ramus osteotomy with and without presurgical orthodontic treatment. Methods: This retrospective study included 29 patients with skeletal Class III malocclusion and facial asymmetry including menton deviation > 4 mm from the midsagittal plane. To evaluate changes in transverse skeletal and dental variables (i.e., buccolingual inclination of the upper and lower canines and first molars), the data for 16 patients who underwent conventional orthognathic surgery (CS) were compared with those for 13 patients who underwent preorthodontic orthognathic surgery (POGS), using three-dimensional computed tomography at initial examination, 1 month before surgery, and at 7 days and 1 year after surgery. Results: The 1-year postsurgical examination revealed no significant changes in the postoperative transverse dental axis in the CS group. In the POGS group, the upper first molar inclined lingually on both sides (deviated side, $-1.8^{\circ}{\pm}2.8^{\circ}$, p = 0.044; nondeviated side, $-3.7^{\circ}{\pm}3.3^{\circ}$, p = 0.001) and the lower canine inclined lingually on the nondeviated side ($4.0^{\circ}{\pm}5.4^{\circ}$, p = 0.022) during postsurgical orthodontic treatment. There were no significant differences in the skeletal and dental variables between the two groups at 1 year after surgery. Conclusions: POGS may be a clinically acceptable alternative to CS as a treatment to achieve stable transverse axes of the dentition in both arches in patients with skeletal Class III malocclusion and facial asymmetry.

• Journal of Oral Medicine and Pain
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• v.41 no.4
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• pp.169-179
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• 2016

Purpose: This study is designed to analyse etiology and bone pattern at the first visit using cone-beam computed tomography (CBCT) and to evaluate the treatment outcome of conservative treatment in temporomandibular disorder (TMD) patients with rheumatoid arthritis (RA). Methods: One hundred condyles in 50 subjects with RA were chosen among the patients who presented to the Department of Oral Medicine of Pusan National University Dental Hospital, diagnosed as TMD. Condylar bone changes were classified by normal, erosive bony change, proliferative bony change and combined group (erosive bony change+proliferative bony change). They were treated conservatively with physical therapy, medication, behavioral therapy and/or occlusal stabilizing splint therapy. After 3 months on average, patients were re-evaluated with regards to subjective symptoms and the clinical findings were investigated. Results: TMD patients with RA have behavioral contributing factors such as parafunctional habit. The results that analyse bone pattern at the first visit using CBCT proliferative bony changes group (32.6%) were more common than erosive bony changes group (15.2%). In comparison between unilateral and bilateral bony change in temporomandibular joint, the ratio showed no significant differences. After 3 months of conservative treatments, pain, noise, limitation of motion (LOM) were markedly improved regardless of occlusal splint therapy. However only LOM was significantly improved through occlusal splint therapy during 3 months. Conclusions: TMD patients with RA had similar behavioral contributing factors and characteristics of CBCT images shown in general TMD patients and also similar response to conservative treatment so it is difficult to differentiate. Therefore when TMD patients show symptoms corresponding to clinical diagnostic criteria of RA at the first visit, serological testing should be conducted and through this, early diagnosis and treatment of RA should be initiated.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6529-6532
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• 2013

Background: Breast cancer is mostly the disease of postmenopausal women but very young affected women are seen more than occasionally in developing countries. We reviewed our cases of very young breast cancer in order to help in better understanding of such cases. Materials and Methods: The records of patients 25 years of age or less who had been admitted for breast cancer surgery in the Cancer Institute of Tehran from 1979 to 2012 were reviewed and relevant data were extracted. Results: From 5,265 cases of breast cancer, 62 patients had 25 years of age or less. There were 55 cases of breast adenocarcinoma, all female. More than 78% of the patients had presented with a palpable mass, the family history was positive in 2% of cases, and about 94% of the histologies were invasive ductal carcinoma. Gestational breast cancer constituted 10% of the cancers; another 10%were bilateral. The median size of the tumors was 5.72 centimeters, 63.2% of them had axillary lymphatic involvement, and more than half were negative for hormone receptors. Conclusions: Our study shows an incidence of 1.17% for very young breast cancer and a 10% rate of bilaterality which probably warrants special guidelines for contralateral screening. Cancer stage and features were poor in comparison with breast cancer in all ages.

• Journal of Integrative Natural Science
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• v.11 no.3
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• pp.139-147
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• 2018

Hippocampal atrophy is a well-established imaging biomarker of Alzheimer disease (AD). However, hippocampus is a non-homogenous structure with cytoarchitecturally and functionally distinct sub-regions or subfield, with each region performing distinct functions. Certain regions of the subfield have shown selective vulnerability to AD. Here, we are interested in studying the effects of normal aging and mild cognitive impairment on these sub-regional volumes. With a reliable automated segmentation technique, we segmented these subregions of the hippocampus in 101 cognitively normal (CN), 135 early mild cognitive impairment (EMCI), 67 late mild cognitive impairment (LMCI) and 48 AD subjects. Thereby, dividing the hippocampus into hippocampal tail (tail), subiculum (SUB), cornu ammonis 1 (CA1), hippocampal fissure (fissure), presubiculum (PSUB), parasubiculum (ParaSUB), molecular layer (ML), granule cells/molecular layer/dentate gyrus (GCMLDG), cornu ammonis 3(CA3), cornu ammonis 4(CA4), fimbria and hippocampal-amygdala transition area (HATA). In this cross sectional study of 351 ADNI subjects, no differences in terms of age, gender, and years of education were observed among the groups. Though, the groups had statistically significant differences (p < 0.05 after the multiple comparison correction) in the Mini-Mental State Examination (MMSE) scores. There was asymmetrical volume loss in the early stages of AD with the left hemisphere showing volume loss in regions that were unaffected in the right hemisphere. Bilateral parasubiculum, right cornu ammonis 1, 3 and 4, right fimbria and right HATA regions did not show any volume loss till the late MCI stages. Our findings suggest that the hippocampal subfield regions are selectively vulnerable to AD and also that these vulnerabilities are asymmetrical especially during the early stages of AD.

• Applied Microscopy
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• v.24 no.4
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• pp.13-31
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• 1994

The fine structure of palisade chloroplasts has been studied in the mature leaves of 3 Dubautia species (D. scabra var. leiophylla, D. knudsenii and D. scabra var. leiophylla${\times}$D. knudsenii) to explore variation at the ultrastructural level, since the parental species exhibit quite different morphological and anatomical features. Types of thylakoidal membrane systems, occurrence and distribution of phytoferritin-like structures, lipid droplets, starch grains, mitochondria and microbodies were examined. Four different types of thylakoidal membranes were found in D. scabra var. leiophylla, 2 rather uniform types in D. knudsenii and 3 intermediate types in their hybrid. D. scabra var. leiophylla and the hybrid were marked by statistically significant differences in mean numbers of thylakoids per granum, while no significant difference was found between D. knudsenii and the hybrid. Phytoferritin-like structures which were about $100-120{\AA}$ in diameter as a whole particle each were found in all 3 species. The amount and distribution of particles varied by species. Lipid droplets, plastoglobuli, and starch grains occurred in all 3 species, but the frequency of starch grains also varied with the species. More frequent and larger starch grains were observed in D. knudsenii than in the other two species. Microbodies, or peroxisome, were observed throughout all species. They occurred, either with or without crystalline inclusions, around the chloroplasts.

• Journal of Veterinary Clinics
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• v.22 no.4
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• pp.382-385
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• 2005

The aim of this study was to compare ultrasonography with video-otoscopy for the evalution of the external ear canal and the tympanum. Fifty dogs with clinical signs ot the bilateral ear diseases were examined using otoscopy under general anesthesia. Ultrasonographic examination was performed with an 11 MHz linear-arrary probe and a 6.5MHz convex probe, with the external ear canal filled with saline. Saline functioned as a contrast media and enhanced image quality of ultrasonography. The images of 100 ears before and after the ear cleansing were obtained at otoscopy and ultrasonography. On the video-otoscopic images, the tympanic membrane was identified in 59 ears before the ear cleansing and 91 ears after cleansing. On the ultrasonography, the tympanic membrane was detected in 98 ears before the ear cleansing and in all ears after cleansing. With these results, it was concluded that ultrasonography with infusing saline into the ear canal, could be a useful diagnostic procedure to identify the tympanic membrane in otitis dogs.

• Journal of the Korea Convergence Society
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• v.9 no.10
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• pp.423-432
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• 2018

The purpose of this study was to investigate the differences in upper and lower strengths and symmetry between upper body injury group, lower body injury group and non-injury group of bowling athletes. The subjects were the upper body injury group (UG), n = 16, the low body injury group (LG), n = 8, the non injury group, [NG], n = 15). The isometric strength of the bowler was measured using Manual Muscle Tester 01165 (Lafayette Instrument Company, USA) and the symmetry index (SI) was calculated. The results were as follow. The symmetry index of hip extension strength and hip external rotation strength was statistically larger in NG than LG (p <.05). The above results suggest that lower body strength and bilateral symmetry was closely related to injuries of the lower body. In order to prevent injury of the bowler, strengthening of lower body strength and symmetrical training are needed.

• Journal of Korean Physical Therapy Science
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• v.13 no.3
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• pp.15-25
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• 2006

The purpose of this study was to investigate effects of different chair type (with backrest chair and without backrest chair) and pelvic position (anterior pelvic tilting and posterior pelvic tilting) on three abdominal muscles (upper rectus abdominis, external oblique, internal oblique) and back extensor activation during lower extremity exercise. The four different conditions during bilateral knee extension exercise were: (1) leaning on backrest chair with anterior pelvic tilting, (2) leaning on backrest chair with posterior pelvic tilting, (3) anterior pelvic tilting without backrest chair, and (4) posterior pelvic tilting without backrest chair. Fifteen healthy male subjects with no history of neuromusculoskeletal disease voluntarily participated in this study. Electromyography (EMG) was used to collect muscle activation data, and muscle activation data was expressed as a percentage of maximal voluntary isometric contraction (%MVIC). One-way repeated analysis of variance (ANOVA) was used to determine the statistical significance, and Bonferroni comparison was used as a post hoc test. The results of this study were the following: (1) Erector spinae activation was significantly lower in posterior pelvic tilting without backrest compared with that in leaning on backrest chair with anterior pelvic tilting. (2) Upper rectus abdominis activation was significantly lower than erector spinae in all four different chair type and pelvic tilting conditions.

• Archives of Plastic Surgery
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• v.44 no.4
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• pp.324-331
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• 2017

Background Lipedema is a condition consisting of painful bilateral increases in subcutaneous fat and interstitial fluid in the limbs with secondary lymphedema and fibrosis during later stages. Combined decongestive therapy (CDT) is the standard of care in most countries. Since the introduction of tumescent technique, liposuction has been used as a surgical treatment option. The aim of this study was to determine the outcome of liposuction used as treatment for lipedema. Methods Twenty-five patients who received 72 liposuction procedures for the treatment of lipedema completed a standardized questionnaire. Lipedema-associated complaints and the need for CDT were assessed for the preoperative period and during 2 separate postoperative follow-ups using a visual analog scale and a composite CDT score. The mean follow-up times for the first postoperative follow-up and the second postoperative follow-up were 16 months and 37 months, respectively. Results Patients showed significant reductions in spontaneous pain, sensitivity to pressure, feeling of tension, bruising, cosmetic impairment, and general impairment to quality of life from the preoperative period to the first postoperative follow-up, and these results remained consistent until the second postoperative follow-up. A comparison of the preoperative period to the last postoperative follow-up, after 4 patients without full preoperative CDT were excluded from the analysis, indicated that the need for CDT was reduced significantly. An analysis of the different stages of the disease also indicated that better and more sustainable results could be achieved if patients were treated in earlier stages. Conclusions Liposuction is effective in the treatment of lipedema and leads to an improvement in quality of life and a decrease in the need for conservative therapy.