• 전자공학회논문지CI
• /
• 제48권1호
• /
• pp.90-100
• /
• 2011

본 연구에서는 연산 부하가 매우 큰 Bio-FET 시뮬레이션을 위해 낮은 비용으로 대규모 병렬처리 환경 구축이 가능한 최신 그래픽 프로세서(GPU)를 이용해서 선형 방정식 해법을 수행하기 위한 병렬 Bi-CG(Bi-Conjugate Gradient) 방식을 제안한다. 제안하는 병렬 방식에서는 반도체 소자 시뮬레이션, 전산유체역학(CFD), 열전달 시뮬레이션 등을 포함한 다양한 분야에서 많은 연산량이 집중되어 전체 시뮬레이션에 필요한 시간을 증가시키는 포아송(Poisson) 방정식의 해를 병렬 방식으로 구한다. 그 결과, 이 논문의 테스트에서 사용된 FDM 3차원 문제 공간에서 단일 CPU 대비 연산 속도가 최대 30 배 이상 증가했다. 실제 구현은 NVIDIA의 태슬라 아키텍처(Tesla Architecture) 기반 GPU에서 범용 목적으로 병렬 프로그래밍이 가능한 NVIDIA사의 CUDA(Compute Unified Device Architecture) 환경에서 수행되었으며 기존 연구가 주로 32 비트 정밀도(single floating point) 실수 범위에서 수행된 것과는 달리 본 연구는 64 비트 정밀도(double floating point) 실수 범위로 수행되어 Bi-CG 해법의 수렴성을 개선했다. 특히, CUDA는 비교적 코딩이 쉬운 반면, 최적화가 어려운 특성이 있어 본 논문에서는 제안하는 Bi-CG 해법에서의 최적화 방향도 논의한다.

• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 1999년도 춘계 학술대회논문집
• /
• pp.106-112
• /
• 1999

In this article, combination of the FAS-FMG multi-grid method and the Krylov subspace method was presented in solving two dimensional driven-cavity flows. Three algorithms of the Krylov subspace method, CG, CGSTAB(Bi-CG Stabilized) and GMRES method were tested with MILU preconditioner. As a smoother of the pressure correction equation, the MILU-CG is recommended rather than MILU-GMRES(k) or MILU-CGSTAB, since the MILU-GMRES(k) preconditioner has too much computation on the coarse grid compared to the MILU-CG one. As for the momentum equation, relatively cheap smoother like SIP solver may be sufficient.

• 미생물학회지
• /
• 제32권1호
• /
• pp.91-95
• /
• 1994

토양에서 분리된 Enterobacter agglomerans CBNU45는 type II 제한효소인 EagBI을 생산하고 있음을 발견하였다. EagBI을 DEAE-cellulose, phosphocellulose P11, hydroxylapatite column chromatography를 거쳐 부분 정제하여 그 특성을 알아보았다. EagBI은 여섯개의 염기배열 5’-CGAT${\downarrow}$CG-3’을 인식하고 T 와 C 사이를 절단하여 두개의 염기가 3’-말단쪽으로 돌출된 cohesive end를 형성하였다. EagBI의 반응 최적조건은 10mM Tris-HCl(pH 7.8), 6~10mM $MgCl_2$, 37${\circ}C$이었으며 NaCl이 없는 반응 완충용액에서 가장 좋은 활성을 보였다. EagBI은 $dam^-$와 $dam^+$ 메칠화 DNA도 절단할 수 있으며 65${\circ}C$에서 10분 동안 열처리하였을 때 효소의 활성을 상실하였다. 따라서 EagBI은 PvuI의 isoschizomer이나 NaCl 요구성과 열안정성에서 PvuI보다 편리한 제한효소로 확인되었다.

• Journal of Acupuncture Research
• /
• 제26권4호
• /
• pp.99-106
• /
• 2009

Objectives : The antidepressant effect of the subchronic administration of the methanolic extract of wild ginseng(WG) was investigated compared with that of cultivated ginseng(CG, panax ginseng) extract. Methods : To assess the antidepressant effect of the ginseng extracts, tail suspension test(TST) was executed in mice after daily administration of WG or CG extract for five consecutive days. Results : The WG extract at daily dose of 600mg/kg significantly reduced the total duration of immobility in the TST, whereas there was no significant reduction at daily dose of 300mg/kg WG and 600mg/kg CG. There were no individual differences between experimental groups in open field test (OFT) to evaluate psychostimulant effects of WG or CG extract. In the high performance liquid chromatography(HPLC) analysis of the extracts, it was found that WG included four times more ginsenoside Rg1 and Re, three times more Rf, and six times more Rb1 and Rc than CG. Conclusions : It is suggested that WG extract has stronger antidepressant effect than CG extract, which means it includes more antidepressant compounds than CG.

• Mycobiology
• /
• 제43권1호
• /
• pp.63-70
• /
• 2015

Phytophthora diseases have become a major impediment in the citrus production in Thailand. In this study, an isolate of Phytophthora denominated as PHY02 was proven to be causal pathogen of root rot of Pomelo (Citrus maxima) in Thailand. The isolate PHY02 was morphologically characterized and identified as Phytophthora palmivora based on molecular analysis of an internal transcribed spacer rDNA sequence. This work also presents in vitro evaluations of the capacities of Chaetomium spp. to control the P. palmivora PHY02. As antagonists, Chaetomium globosum CG05, Chaetomium cupreum CC3003, Chaetomium lucknowense CL01 inhibited 50~61% mycelial growth, degraded mycelia and reduced 92~99% sporangial production of P. palmivora PHY02 in bi-culture test after 30 days. Fungal metabolites from Chaetomium spp. were tested against PHY02. Results showed that, methanol extract of C. globosum CG05 expressed strongest inhibitory effects on mycelial growth and sporangium formation of P. palmivora PHY02 with effective dose ED50 values of $26.5{\mu}g/mL$ and $2.3{\mu}g/mL$, respectively. It is interesting that C. lucknowense is reported for the first time as an effective antagonist against a species of Phytophthora.