• 대한가정학회지
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• 제19권2호
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• pp.151-163
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• 1981

This study was to investigate the changes of shape of the surface square measurements, the rate, measurements of expansion and contraction and correlation. In this study was found the following: 1. According to the developmental illustration of the shell it was revealed that there was a great change in the thigh area of the body. When the leg was raised and the waist bent forward the front sections of the abdomen were contracted and the center back of the hip was expanded. 2. It was found that the contraction was present in the girth of the back section and front section was expanded in the rate of the body surface. In the length from the middle waist to hip the front area showed a great deal of contraction the back area of the hip & thigh revealed a great deal of expansion. 3. By the somatometry, the measurements of the expansion and contraction of the body surface, there was a great change in waist and hip. It revealed that the maximum expansions of waist and hip line in the chair were 1.8cm and 4.08cm respectively. Therefor, when slacks are made at least the amount of ease of 1.8cm of waist line and 4cm of hip line must be made and the allowance of the center back of hip area must be made. 4. It revealed that there was a correlation between waist and hip girth.

• BMB Reports
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• 제51권12호
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• pp.636-641
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• 2018

DPP4 (dipeptidyl peptidase-4), a highly conserved transmembrane glycoprotein with an exo-peptidase activity, has been shown to contribute to glucose metabolism, immune regulation, signal transduction, and cell differentiation. Here, we show that DPP4 is involved in control of activin/nodal signaling in Xenopus early development. In support of this, gain of function of DPP4 augmented Smad2 phosphorylation as well as expression of target genes induced by activin or nodal signal. In addition, Dpp4 and Xnr1 showed synergistic effect on induction of ectopic dorsal body axis, when co-injected at suboptimal doses in early embryos. Conversely, saxagliptin, a DPP4 inhibitor repressed activin induction of Smad2 phosphorylation. Notably, overexpression of Dpp4 disrupted specification of dorsal body axis of embryo, leading to malformed phenotypes such as spina bifida and a shortened and dorsally bent axis. Together, these results suggest that DPP4 functions as a potentiator of activin/nodal signaling pathway.

• International Journal of Costume and Fashion
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• 제5권1호
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• pp.1-13
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• 2005

Two hundreds of female aged 19 years old and up were recruited to evaluate the postural changes and bilateral variation of asymmetry over age. To find out the differences among the age group, subjects were classified into 5 groups, early young age(19-29), late young age(30-39), early middle age(40-49), late middle age(50-59), and old age(60-). 35 body measurements were taken by the 3-D body scanner which allowed us to take measurements which cannot be measured using traditional methods, including the shape of a cross section, slice area surface are, and volume. Bilateral variations were observed as a function of age; Depth of scapular point level, scapular point to center back, and blade angle. Postural change of anterior cervical angle, upper anterior thoracic angle, upper posterior thoracic angle, posterior cervical angle, and center back/center front ratio were also exhibited. In each measurements, subjects were classified into normal, and abnormal group. Percentiles of abnormal in shoulder line angle, blade angle, neck point $\∼$ acromial point $\∼$ scapular point, posterior cervical angle, and upper posterior thoracic angle were increased over age group. The upper body of lateral view was classified into 3 types of posture based on the previous research; straight, erect(leaning back), and stooped(bent forward). The percentiles of subjects who have straight postures were decreased as a function of age, but those of stooped postures were increased. Subjects who have erect postures did not so. The stooped posture group shows the big cervical fossa angle, anterior cervical angle, posterior cervical angle, upper posterior thoracic angle, and the small upper anterior thoracic angle comparing to the straight and erect posture group. These results could be apply for clothing construction reflecting the changes in back, shoulder, neck, and the bilateral asymmetry according to the target age group.

• Nuclear Engineering and Technology
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• 제11권1호
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• pp.1-20
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• 1979

수화물 결정에 있어서 $H_2O$ 분자의 외부 각 운동을 조사하고저 NaBr-2$H_2O$ 및 BaCl$_2$-2$H_2O$ 분말시료에 대한 중성자비탄성산란실험을 수행하였으며, 관측된 진동수를 모두 이 외부 각 운동에 의한 것으로 보고 다중 및 다준위산란효과를 제거하므로서 평균진동수 분포함수를 구하였다. FG 행열법에 의해서 계산된 진동수의 이론 값들은 모두 복합 mode에 의한 것이였으며 따라서 그 중 포텔샬.에너지분포가 큰 mode로서 관측치에 대한 assignment를 하였다. 소수결합력은 Lippincott-Schroeder 포텐샬함수에서 추산하였으며, 절선형 및 분기형수소결합에 대한 이 함수의 유용성을 $H_2O$ 외부 각 운동 포텐샬함수 모양에 의거하여 검토하였다. 수소결합력의 성질에 대하여 더욱 자세한 자료를 얻기 위해서는 진동수 계산에 H…Y 신축상호작용 운만 아니라 O-H…Y 변각상호작용의 도입이 필요함을 논의하였고 또 $H_2O$ 외부 각 운동에 인어서 mode의 순수성 및 대칭성을 군론을 작용한 방법에 의거하여 논의하였다.

• 한국발생생물학회지:발생과생식
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• 제13권4호
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• pp.321-327
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• 2009

망간은 정소 독성을 나타내며, 뇌기저핵에 작용하여 혈청 프로락틴의 농도를 증가시킨다. 그리고 혈청 프로락틴 농도 상승에 의한 과프로락틴혈증(hyperprolactinemia)은 정소의 정자 생성을 억제한다. 본 연구에서는 망간의 전신 노출이 흰쥐 정소의 정자 생산과 혈청 프로락틴 농도에 미치는 영향을 조사하기 위하여 실험동물을 대조군 $(0.0mg/m^3)$과 망간 노출군 (Mn $1.5mg/m^3$)으로 나누고, 노출군은 다시 노출 기간에 따라 4주와 13주 노출군 등 4군으로 분류하였다(n=10). 노출 기간에 따라 실험동물의 체중 변화와 사료 섭취량 등 일반적 소견 관찰, 혈액과 정소의 망간 농도, 정자의 수와 기형 등을 관찰하였다. 그리고 망간 노출에 따른 혈청 프로락틴 농도를 조사하여 망간 노출 조건에 따른 혈청 프로락틴 농도 변화 및 정소 독성을 조사하였다. 망간 노출 4주 및 13주군에서 노출기간에 따라 혈액 및 정소의 망간 농도가 유의하게 증가되었다. 대조군에 비하여 망간 노출군에서 노출기간에 따라 정자의 수가 감소되었으며, small head와 bent tail 등 기형 정자의 빈도는 증가하였다. 혈청 프로락틴의 농도는 망간 투여군에서 대조군에 비하여 유의하게 증가하였다. 그러나 실험동물의 체중 변화 및 사료 섭취량은 실험군간에 차이가 없었다. 이러한 결과들로 보아 $1.5mg/m^3$ 농도의 아만성 망간 노출은 흰쥐의 혈청 프로락틴 농도를 증가시키고, 정소 독성의 원인으로 추정된다. 그리고 전신 노출에 의한 망간의 흰쥐 정소 독성의 무유해영향농도(NOAEL)는 $1.5mg/m^3$ 이하로 예측된다.

• 대한기계학회논문집B
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• 제38권9호
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• pp.739-745
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• 2014

심장 질환 환자에게 약물 치료를 시행하고 있으나, 통상의 약물 치료만으로는 심장질환을 치료하기에는 부족하다. 그러나 LVAD 를 이식한다면 심장기능을 보조하여 심장 이식까지의 가교 역할로서 효과가 있다고 보고되고 있다. 본 연구에서는 선행 연구로 개발된 곡관형 LVAD 인 LibraHeart-I(LH-1)을 이용하여, 대동물(Bovine model, Holstein)과 소동물(canine model, Labrador-retriever)을 대상으로 장기간 동물실험 및 응급상황에서의 생체적합성을 평가하고자 한다. 대동물을 대상으로 실시한 장기간의 동물 실험에서 49 일 생존하였으며, 실험기간 동안 실시한 혈액 검사 및 생징후에서 특이 소견을 관찰되지 않았다. 소동물을 대상으로 한 단기간의 동물 실험에서는 외부 구동부의 동력 지원 없이도 LH-I 내에 혈액이 머무르지 않는 것으로 관찰되었다. 본 연구에서는 장기간 동물실험 및 응급상황에서의 박출 성능을 통해 선행 연구로 개발된 LH-I의 생체적합성을 검증하였다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 춘계학술대회 및 기술 세미나 논문집 디스플레이 광소자
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• pp.42-42
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• 2008

Considerable attention has been focused on the applications of flexible liquid crystal (LC)-based displays because of their many potential advantages, such as portability, durability, light weight, thin packaging, flexibility, and low power consumption. To develop flexible LCDs that are capable of delivering high-quality moving images, like conventional glass-substrate LCDs, the LC device structure must have a stable alignment layer of LC molecules, concurrently support uniform cell gaps, and tightly bind two flexible substrates under external tension. However, stable LC molecular alignment has not been achieved because of the layerless LC alignment, and consequently high-quality images cannot be guaranteed. To solve these critical problems, we have proposed a PDMS pixel-wall based bonding method via the IB irradiation was developed for fasten the two substrates together strongly and maintain uniform cell gaps. The effect of the IB irradiation on PDMS with PI surface was also evaluated by side structure configuration and a result of x-ray photoelectron spectroscopic analysis of PDMS interlayer as a function of binder with substrates. large number of PDMS pixel-walls are tightly fastened to the surface of each flexible substrate and could maintain a constant cell gap between the LC molecules without using any other epoxy or polymer. To enhance the electro-optical performance of the LC device, we applied an alignment method that creates pretilt angle on the PI surface via ion beam irradiation. Using this approach, our flexible LCDs have a contrast ratio of 132:1 and a response time of about 15 ms, resulting in highly reliable electro-optical performance in the bent state, comparable to that of glass-substrate LCDs.

• Tribology and Lubricants
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• 제30권4호
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• pp.218-223
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• 2014

This paper presents a method of controlling the stiffness of a tungsten probe for an atomic force microscope (AFM) in order to provide high-quality phase contrast images in accordance with sample characteristics. While inducing sufficient deformation on sample surfaces with commercial Si or $Si_3N_4$ probes is difficult because of their low stiffness, a tungsten probe fabricated by electrochemical etching with appropriately high stiffness can generate relatively large elastic deformation without damaging sample surfaces. The fabrication of the tungsten probe involves two separate procedures. The first procedure involves immersing a tungsten wire with both ends bent parallel to the surface of an electrolyte and controlling the stiffness of the tungsten cantilever by decreasing its diameter using electrochemical etching in the direction of the central axis. The second procedure involves immersing the end of the etched tungsten cantilever in the direction perpendicular to the surface of the electrolyte and fabricating a tungsten tip with a tip radius of 20-50 nm via the necking phenomenon. The latter etching process applies pulse waves every 0.25 seconds to the manufactured tip to improve its yield. Finite element analysis (FEA) of the stiffness of the tungsten probe as a function of its diameter showed that the stiffness of the tungsten probes greatly varies from 56 N/m to 3501 N/m according to the cantilever diameters from $30{\mu}m$ to $100{\mu}m$, respectively. Thus, the proposed etching method is effective for producing a tungsten probe having specific stiffness for optimal use with an AFM and certain samples.

• 대한가정학회지
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• 제17권4호
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• pp.1-14
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• 1979

The functional problems of the basic pattern of clothing are a matter of the first importance to clothing construction. Therefore, the ergonomic analysis of the expansion and contraction of the upper body surface, due to motion, has become required. thus in order to obtain the measurements and rate of expansion and contraction of the upper body surface following from its motions, the development figure of " Shell" and somatometry were employed. The results obtained through the investigation can be summarized as follows : 1) According to the developmental figures of "Shell" the latitudes centering around the shoulder line present contractive tendencies by arm movement. The longitudes around the center back waist length are expansive tendencies when bent forward. In the case of a 15$^{\circ}$ lean backward posture, the longitudes around the center front waist length are expansive tendencies. 2) By somatometry, the region from the scapula to the axilla point the upper back with presents the greatest expansion (more than 30%). The region from scapla to arm presents the maximum rate of contraction. In considering the longitude , under the axilla waist length and the bust point waist length generally shows the greatest rate of expansion. 3) The bust point waist length and under the axilla waist length are of great importance to the basic pattern of clothing. and have expansive tendencies(6.3cm). Among the latitudes, the upper back width has the greatest tendency for expansion (7.83 cm). 4) The region which presents the greatest rate of the expansion and contraction is in the proximity of the arm. These results testify that the amount of room of the back width must be given consideration in constructing the basic pattern of clothing.pattern of clothing.

• 한국실내디자인학회논문집
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• 제13권5호
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• pp.162-172
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• 2004

Architects and designers of the 20th Century made various efforts to establish new design languages reflecting the changes of society, the times, and environment. They used furniture, especially chairs, as controversial items of aesthetic value, society and ideology. Le Corbusier and Alvar Aalto are furniture designers as well as architects, who adopted this ‘spirit of the times’ actively and have greatly contributed to modernism. This study will help us to understand the diversity of design since modernism, by comparing these two designers' furniture design. It also covers the common factors In modern furniture design, and analyses their individuality and likeness In design. The following is a comparison of furniture design by Le Corbusier and Alvar Aalto. Le Courbusier linked International design and Aalto linked Rational design and Organic concept design to their furniture, just as they did in their architecture. They were able to establish the base of modern furniture design by adapting new concepts and pursuing humanism. In structure, Le Corbusier's furniture Is simple and proportional. It demonstrates a sophisticated geometric composition, mechanical beauty. On the other hand, Aalto rationally linked nature with human requirements and his furniture is organic and in harmony with geometric structure. In function, Le Corbusier's furniture is standardized and prefabricated. He designed for the user so they could choose to use the furniture efficiently to suit their needs. In comparison with Le Corbusier, Aalto Invented the ‘Stacking Chair’ which allows a more effective use of space and reflected the structure of the human body to improve the user's comfort. In materials and techniques, Le Corbusier used new materials like metal or leather, and attempted new ways such as welding, prefabrication, and standardization for production. On the contrary, Alto mainly used birch, which is the traditional material in Finland, and tried new bent wood techniques and joining methods.