• 대한골관절종양학회지
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• 제6권4호
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• pp.168-172
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• 2000

양성 연부조직 간엽세포종은 최소한 두개 이상의 간엽세포조직이 한 종물에 포함된 종양으로 이들 조직세포들은 흔히 같이 발견되지 않는 것들이다. 전세계적으로 적은 수의 양성 간엽 세포종이 보고되고 있으며, 특히 연골 세포 조직이 주를 이루는 경우는 극히 드문 경우로 현재까지 보고된 11개의 증례가 문헌에 보고되고 있다. 저자는 3세 유아에서 흉추 배부에 발생한 연골세포가 주성분으로 구성된 양성 간엽세포종을 경험한 바 고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제23권6호
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• pp.1244-1250
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• 1990

Hamartoma had been considered as a congenital malformation of a tumerous lesion since the original description by Albrecht in 1904. Pulmonary hamartoma is able to classified as endobronchial and intrapulmonary hamartoma clinically, and is considered to benign mesenchymal neoplasms which originated in peribronchial connective tissue, and so called mesenchymoma by someone. We have experienced 3 cases intrapulmonary hamartoma which were discovered during routine chest film check up at all cases and are able to detailed histologic examination by electron microscopy at one case.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2313-2316
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• 2015

Objective: To investigate the correlation between extracellular matrix protein-1 (ECM1) and the growth, metastasis and angiogenesis of laryngeal carcinoma. Materials and Methods: Forty-five samples with laryngeal benign and malignant tumors confirmed by pathology in Laiwu City People's Hospital from March 2006 to March 2011 were collected, in which there were 29 cases with laryngeal carcinoma and 16 with benign tumors. The expression of ECM1 and factor VIII-related antigens in patients with laryngeal carcinoma and those with benign tumors was respectively detected using immunohistochemical method, and the correlation between ECM1 staining grade and microvessel density (MVD) was analyzed. Results: In laryngeal carcinoma tissue, ECM1 was mainly expressed in cytoplasm, less in cytomembrane or intercellular substance. With abundant expression in the tissue of laryngeal benign tumors (benign mesenchymoma and hemangioma), ECM1 was primarily expressed in the connective tissue, which was different from the expression in laryngeal carcinoma tissue. The proportion of positive ECM1 staining (++) in patients with laryngeal carcinoma was dramatically higher than those with benign tumors (p<0.05), and that of strongly-positive ECM1 staining (+++) slightly higher. The results of Spearman nonparametric correlation analysis revealed that ECM1 staining grade in laryngeal carcinoma tissue had a significantly-positive correlation with MVD (r=0.866, p=0.000). Conclusions: ECM1 expression in laryngeal carcinoma is closely associated with tumor cell growth, metastasis and angiogenesis, which can be considered as an effective predictor in the occurrence and postoperative recurrence of laryngeal carcinoma.