• Title/Summary/Keyword: Benefit ratio

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Evaluation of Tank Capacity of Rainwater Harvesting System to Secure Economic Feasibility and Sensitivity Analysis (경제성 확보를 위한 빗물이용시설의 규모 산정 및 민감도 분석)

  • Mun, Jung-Soo;Kim, Ha-Na;Park, Jong-Bin;Lee, Jung-Hun;Kim, Ree-Ho
    • Journal of Korean Society of Water and Wastewater
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    • v.26 no.2
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    • pp.191-199
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    • 2012
  • Rainwater harvesting systems (RWHS), one of measures for on site rainwater management, have been promoted by laws, regulations and guidelines and have been increased. However, more evaluation of economic feasibility on RWHS is still needed due to seasonal imbalance of rainfall and little experiences and analysis on design and operation of RWHS. In this study, we investigated tank capacity of RWHS to secure economic validity considering catchment area and water demand, which is affected by building scale. Moreover, sensitivity analysis was performed to examine the effect of design factors, cost items and increase rate of water service charge on economic feasibility. The BCR (benefit cost ratio) is proportional to the increase in tank capacity. It is increased steeply in small tank capacity due to the effect of cost and, since then, gently in middle and large tank capacity. In case of 0.05 in the rate of tank volume to catchment area and 0.005 in water demand to catchment area, BCR was over one from the tank capacity of 160 $m^{3}$ taking into account of private benefits and from the tank capacity of 100 $m^{3}$ taking into account of private and public benefits. Sensitivity analysis shows that increase of water demand can improve BCR values with little cost so that it is needed to extend application of rainwater use and select a proper range of design factor. Decrease of construction and maintenance cost reduced the tank volume to secure economic validity. Finally, increase rate of water service charge had considerable impact on economic feasibility.

Quasi-static test of the precast-concrete pile foundation for railway bridge construction

  • Zhang, Xiyin;Chen, Xingchong;Wang, Yi;Ding, Mingbo;Lu, Jinhua;Ma, Huajun
    • Advances in concrete construction
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    • v.10 no.1
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    • pp.49-59
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    • 2020
  • Precast concrete elements in accelerated bridge construction (ABC) extends from superstructure to substructure, precast pile foundation has proven a benefit for regions with fragile ecological environment and adverse geological condition. There is still a lack of knowledge of the seismic behavior and performance of the precast pile foundation. In this study, a 1/8 scaled model of precast pile foundation with elevated cap is fabricated for quasi-static test. The failure mechanism and responses of the precast pile-soil interaction system are analyzed. It is shown that damage occurs primarily in precast pile-soil interaction system and the bridge pier keeps elastic state because of its relatively large cross-section designed for railways. The vulnerable part of the precast pile with elevated cap is located at the embedded section, but no plastic hinge forms along the pile depth under cyclic loading. Hysteretic curves show no significant strength degradation but obvious stiffness degradation throughout the loading process. The energy dissipation capacity of the precast pile-soil interaction system is discussed by using index of the equivalent viscous damping ratio. It can be found that the energy dissipation capacity decreases with the increase of loading displacement due to the unyielding pile reinforcements and potential pile uplift. It is expected to promote the use of precast pile foundation in accelerated bridge construction (ABC) of railways designed in seismic regions.

FRET-Based Quantitative Discrimination of Bisulfite-Untreated DNA from Bisulfite-Treated DNA

  • Lee, Eun Jeong;Cho, Yea Seul;Song, Seongeun;Hwang, Sang-Hyun;Hah, Sang Soo
    • Bulletin of the Korean Chemical Society
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    • v.35 no.5
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    • pp.1455-1459
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    • 2014
  • We report a sensitive and reliable FRET-based nanotechnology assay for efficient detection and quantification of bisulfite-unmodified or modified DNA. Bisulfite-untreated DNA or bisulfite-treated DNA is subjected to PCR amplification with biotin-conjugated primers so that the amounts of bisulfite-untreated and treated DNA can be differentiated. Streptavidin-coated quantum dots (QDs) are used to capture biotinylated PCR products intercalated with SYBR Green, enabling FRET measurement. Key features of our method include its low intrinsic background noise, high resolution, and high sensitivity, enabling detection of as little as 1.75 ng of bisulfite-untreated DNA in the presence of an approximately 1,000-fold excess of bisulfite-untreated DNA compared to bisulfate-treated DNA, with the use of PCR reduced (as low as 15 cycles). SYBR Green as an intercalating dye as well as a FRET acceptor allows for a single-step preparation without the need for primers or probes to be chemically conjugated to an organic fluorophore. Multiple acceptors per FRET donor significantly enhance the signal-to-noise ratio as well. In consideration of the high relevance of bisulfite treatment to DNA methylation quantitation, our system for FRET measurement between QDs and intercalating dyes can be generally utilized to analyze DNA methylation and to potentially benefit the scientific and clinical community.

Application of Concentrated FRP Bars to Enhance the Capacity of Two-Way Slabs (2방향 슬래브의 성능 향상을 위한 집중 배근된 FRP 바의 적용)

  • Lee, Joo-Ha;Yang, Jun-Mo;Yoon, Young-Soo
    • Journal of the Korea Concrete Institute
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    • v.19 no.6
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    • pp.727-734
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    • 2007
  • The influence of the differences in the physical and mechanical properties between fiber-reinforced polymer (FRP) and conventional steel, concentrated reinforcement in the immediate column region, as well as using steel fiber-reinforced concrete (SFRC) in the slab near the column faces, on the punching behavior of two-way slabs were investigated. The punching shear capacity, stiffness, ductility, strain distribution, and crack control were investigated. Concentrating of the slab reinforcement and the use of SFRC in the slab enhanced the punching behavior of the slabs reinforced with glass fiber-reinforced polymer (GFRP) bars. In addition the test results of the slabs with concentrated reinforcement were compared with various code equations and the predictions proposed in the literature specifically for FRP-reinforced slabs. An appropriate method for determining the reinforcement ratio of slabs with a banded distribution was also investigated to allow predictions to properly reflect the benefit of the slab reinforcement concentration.

CHANGES OF SERUM ALKALINE PHOSPHATASE AFTER ENUCLEATION OF CYSTS IN THE JAWS (낭종 수술 전후에 있어서 혈중 Alkaline Phosphatase의 변화에 대한 연구)

  • Eune, Jung-Ju;Lee, Eui-Seok;Rim, Jae-Suk;Jang, Hyon-Seok;Woo, Hyon-Il
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.31 no.5
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    • pp.417-421
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    • 2005
  • This study was to analyze the changes of levels of alkaline phosphatase before and after enucleation of jaw cysts combined with bone grafting, and to evaluate biochemically the effectiveness of the early detection of bone healing and infection as a prognostic marker. Eighteen patients (13 males, 5 females) with cystic lesions of the jaws were divided into two groups. The bone graft group underwent enucleation and bone graft. The control group underwent only enucleation. Both groups were measured levels of ALP before surgery, and plus-minus 4 weeks postoperatively. The more discriminating results were obtained in the bone graft group. The results were as follows : 1. Levels of ALP after enucleation of jaw cysts were decreased in all patients with and without bone graft. 2. The bone graft group showed more marked decrease in variation of levels of ALP than the control group.(p=0.008) This should be considered as a result of increased osteoblastic activity and new bone formation. 3. Such variation could be used as a prognostic marker for bone healing after cyst operation. In the cost/benefit ratio, measurement of ALP activity could be useful as a convenient procedure in routine clinical practice.

A Follow-up Study for the International Science Olympiad Prizewinners (국제과학올림피아드 참가자의 진로에 대한 연구)

  • Shim, Jae-Young;Jung, Sea-Hwan;Lee, Gill-Seung
    • Journal of Gifted/Talented Education
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    • v.17 no.1
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    • pp.145-171
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    • 2007
  • The purpose of this research aimed to analyze of the present database for the International Science Olympiad participants, to survey opinions for the Olympiad, and to figure for the better performance. For the present database of International Science Olympiad participants, we analyzed the data of KOSEF(Korea Science and Engineering Foundation). The subjects for survey are the participants of the International Science Olympiad. They are totally 277 persons and 250 of those were prizewinners. The results are as follows. The International Science Olympiad Prizewinners are increasing continuously. In regard of their career, the ratio of participants who went on to engineering fields of universities is 74.4%, to the medical profession 20.4%, the others 5.2%. The portion of students who choose medical profession were increasing since 1998 rapidly. The subjects responded the best benefit for the Olympiad were college-preparatory(60.0%) but they said they also lost the opportunity to study diversely.

Establishment of artifical cultivation technique of Pleurotus ostreatus using an onion net (양파망을 이용한 느타리버섯(Pleurotus ostreatus) 재배기술)

  • Yu, Young-Jin;Seo, Sang-Young;Jung, Gi-Tai;Ryu, Jeong;Ko, Bok-Rai;Choi, Joung-Sik;Kim, Myung-Kon
    • Journal of Mushroom
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    • v.4 no.3
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    • pp.101-105
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    • 2006
  • This was performed to improve the working conditions of oyster mushroom cultivation on bed using rice straw of which binding and cutting procedure need a lot of time. There was a little difference in physiochemical components between rice straw and cotton waste C/N ration of cotten waste was, however, similar to rice straw as 84-85. If is feasible to use as substrate material. The average yield of a net was 1450g in six frustration harvest, when the size of an onion net was $35{\times}30cm$, mixture ratio of rice straw to cotton waste was 40:60(V/V). Cultivation method using an onion net saved 3 days for preparation, 4 hours for inoculation compared to normal bed cultivation. This method was analysed to give 5% economical benefit.

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Medical review of Insurance claims for GIST and MALToma (기스트와 말토마의 보험의학적 악성도 판단)

  • Lee, Sin-Hyung
    • The Journal of the Korean life insurance medical association
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    • v.27 no.2
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    • pp.68-74
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    • 2008
  • Medical verification of cancer diagnosis in insurance claims is a very important procedure in insurance administrations. Claims staffs are in need of medical experts' opinions about claim administration. This procedure is called medical claim review (MCR) and is composed of verification and advice. MCR verification evaluates the insured’s physical condition by medical records and compares it with product coverage. It is divided into assessment of living assurance benefit, verification of cancer, and assessment of the cause of death. Actually cancer verification of MCR is applicable to coding because the risk ratio in product development is usually coded data. There are some confusing neoplastic diseases in assessing the verification of cancer. This article reviews gastrointestinal stromal tumors (GIST) and mucosa-associated lymphoid tissue tumors (MALToma) of the stomach. The second most common group of stromal or mesenchymal neoplasms affecting the gastrointestinal tract is GIST. Nowadays there are many articles about the pathophysiology of GIST. However there are few confirmative theories except molecular cell biology of KIT mutation and some tyrosine kinase. Therefore, coding the GIST, which has previously been classified as an intermediate risk group according to NIH2001 criteria, for cancer verification of MCR is suitable for D37.1; neoplasm of uncertain or unknown behavior of digestive organs and the stomach. The gastrointestinal tract is the predominant site of extranodal non-Hodgkin's lymphomas. B-cell lymphomas of the MALT type, now called extranodal marginal zone B-cell lymphoma of MALT type in the REAL/WHO classification, are the most common primary gastric lymphomas worldwide. Its characteristics are as follows. First, it is different from traditional stomach cancers such as gastric adenocarcinoma. Second, the primary therapy of MALToma is the eradication of H. pylori by antibiotics and the remission rate is over 80%. Third, it has a different clinical course compared to traditional malignant lymphoma. Someone insisted that cancer verification is not possible for the above reasons. However, there have been findings on pathologic mechanism, and according to WHO classification, MALToma is classified into malignant B-cell lymphoma and it must be verified as malignancy in MCR.

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THE USE OF MULTINUTRIENT BLOCK SUPPLEMENTED TO UREA TREATED RICE STRAW BASE DIET FOR DAIRY HEIFERS

  • Cheva-Isarakul, B.;Promma, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.8 no.2
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    • pp.113-118
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    • 1995
  • Eighteen Holstein Friesian ${\times}$ Native heifers with an average live weight of $175.4{\pm}27.8kg$ were allotted to 3 dietary groups. All animals were kept individually in a stanchion barn with free access to water and urea-treated rice straw (UTS). The supplemented feeds were as follows: Group (Gr) 1 - concentrate mixture (15% CP) at 1% body weight (BW), Gr 2 - concentrate mixture at 0.7% BW + free licking of multinutrient block (MNB), Gr 3 - as Gr 2 + 0.3% BW ground com. Multinutrient block composed of 20% mineral mixture, 10% urea, 18% molasses, 20% soybean meal, 22% sesame meal, 10% cement, 0.15 million IU and 50 IU/kg MNB of vitamin A and E. The experimental period lasted 12 weeks. The result revealed that MNB enhanced intake of UTS and total dry matter intake. Animals in Gr 3 consumed a higher amount of feed than the other 2 groups, thus resulting in the highest live weight gain and tended to possess the best feed conversion ratio. Heifers in Gr 2 also performed better than Gr 1 although the difference was not significant. Average MNB intake found to be 0.65 kg/day. Feed cost per kg gain was not significantly different amon groups. However if the cost of MNB could be lower, it would benefit the production cost of animals. The advantage of MNB is the safety of using a high level of urea. Although it was supplemented to UTS which also contained non-protein nitrogen (NPN), no toxic sign was shown. The results indicated that MNB could be partially substituted to concentrate mixture and it was even better when used incombination with soluble carbohydrate feed.

Prognostic Factors and the Role of Adjuvant Chemotherapy in Post-curative Surgery for Dukes B and C Colon Cancers and Survival Outcomes: a Malaysian Experience

  • Hassan, Astrid Sinarti;Naicker, Manimalar;Yusof, Khairul Hazdi;Ishak, Wan Zamaniah Wan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.6
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    • pp.2237-2243
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    • 2015
  • Background: Adjuvant chemotherapy improves survival in Dukes C colon cancers post-curative resection. However, the evidence for a role with Dukes B lesions remains unproven despite frequent use for disease characterized by poor prognostic features. In view of limited Asia-specific data, this study aimed to determine survival outcomes and identify prognostic factors in a tertiary teaching hospital in Malaysia. Materials and Methods: A total of 116 subjects who underwent curative surgery with and without adjuvant chemotherapy for Duke B and C primary colon adenocarcinomas diagnosed from 2004-2009 were recruited and data were collected retrospectively. Five-year overall survival (OS) and disease free survival (DFS) were analysed using Kaplan-Meier survival analysis and log-rank (Mantel-Cox) test. Prognostic factors were determined using Cox proportional hazards regression with both univariate and multivariate analyses. Results: The survival analysis demonstrated a 5-year OS of 74.0% for all patients, with 74.9% for Dukes C subjects receiving chemotherapy compared to 28.6% in those not receiving chemotherapy (p=0.001). For Dukes B disease, the 5-year survival rate was 82.6% compared to 75.0% for subjects receiving and not receiving chemotherapy, respectively (p=0.17). Independent prognostic factors identified included a CEA level more than 3.5 ng/ml (hazard ratio (HR)=4.78; p=0.008), serosal involvement (HR=3.75; p=0.028) and completion of chemotherapy (HR= 0.20; p=0.007). Conclusions: In a regional context, this study supports current evidence from the West that adjuvant chemotherapy improves survival in Dukes C colon cancers post curative surgery. However, although a clear benefit has yet to be proven for Dukes B disease, our results suggest survival improvement in selected cases.