• Title/Summary/Keyword: Benefit criteria

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Drug Use Evaluation of Letrozole in Breast Cancer Patients at Regional Cancer Hospitals in Thailand

  • Ketkaew, Chaninun;Kiatying-Angsulee, Niyada
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.6055-6059
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    • 2015
  • Background: Medication policy development in Thailand is continually promoting rational drug use. Letrozole, an endocrine therapy drug, is usually prescribed for post-menopausal status early and advanced stage breast cancer. After Ministry of Public Health announced Letrozole as compulsory licensed drug in 2009, more breast cancer patients can access to this drug at low cost especially those within universal coverage schemes. To ensure that Letrozole is rationally prescribed, the drug utilization study was conducted. Objectives: The aim of this study was to describe the appropriate use of Letrozole in breast cancer and the relationship between appropriate use and health benefit schemes. Materials and Methods: A retrospective study to evaluate use of Letrozole in breast cancer patients was performed for six months between January - June 2010 in seven regional cancer hospitals, Thailand. All prescriptions of Letrozole were identified from pharmacy dispensing databases and prescription papers. A medical record review was also performed to evaluate appropriate use referring to the drug use evaluation criteria. The approved criterion of this study was referred from the guideline of Thai National Formulary version 2010. Results: There were 681 prescriptions of Letrozole for 254 breast cancer patients with an average age of $58.6{\pm}10.0years$. The patients in universal coverage scheme (UCS), civil servant medication benefit scheme (CSMBS) and social security scheme (SSS) were 77.7%, 18.5% and 8.7% respectively. 10.6% were prescribed Letrozole for the first time. Letrozole were prescribed by oncologists (82.8%). The average number of tablets per prescription was $58{\pm}10$. Calcium supplements were prescribed concomitant with Letrozole for 19.4%. To assess drug use evaluation criteria, 45 prescriptions were excluded because of uncompleted clinical data, 636 prescriptions were evaluated. The study showed 86 prescriptions (13.5%) with inappropriate use including 6 (0.9%) not prescribed for estrogen receptor (ER) and/or progesterone receptor (PR) positive, 31 (4.9%) not prescribed for post-menopausal and 49 (7.7%) not prescribed for an appropriate duration. Appropriate use percentages in different health benefit schemes were similar, 85.7% of CSMBS, 86.4% of SSS and 86.7% of UCS. The relationship between health benefit scheme and appropriate use of Letrozole was not significantly different, ${\chi}^2$ (2, N = 636) = 0.081, p > 0.05. Conclusions: The study showed inappropriate use in breast cancer patients because of non-compliance with duration, menopausal status and hormone receptor requirements. To prescribe appropriate indication did not referred to the appropriate practice along the treatment. Drug use evaluation proved very useful for detecting the sign of inappropriate use and allows immediate feedback to the stakeholder for developing medication policy in the future. Importantly, there was no significantly difference in appropriate use of Letrozole across health benefit schemes.

Development of the Cost-Benefit Analysis System for the Investment of Safety Facilities in Chemical Plant (화학공장의 안전 설비 투자를 위한 비용$\cdot$편익 분석 시스템 개발)

  • Ko J. W.;Seo J. M.;Kim D. H.
    • Journal of the Korean Institute of Gas
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    • v.7 no.4 s.21
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    • pp.61-66
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    • 2003
  • The objective of this study is to develop a Cost-Benefit analysis system which would help us to make optimal decision among safety investment alternatives, calculating and comparing costs and benefits for facilities in chemical plants. So, the accident frequency analysis module and the accident damage prediction module were developed for estimating quantitative risks in chemical facilities, and domestic societal risk criterion was presented after the comparative analysis of major industrial cases and societal risk criteria of advanced countries like the Netherlands, Australia, U.S.A., U.K., and Germany. Also, the Cost-Benefit Analysis System which compares the safety investment alternatives based on their deduced net present values was developed through the selection of proper cost and benefit items by field studies

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User Benefits Analysis of Customized House Design Guidelines for Physically Disabled People (지체장애인 맞춤형주택 디자인가이드라인의 사용자혜택 분석)

  • Lee, Yeun-Sook;Jang, Mi-Seon;Park, Ji-Young
    • Journal of the Korean housing association
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    • v.26 no.6
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    • pp.93-102
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    • 2015
  • Most existing residential environment of disabled people has made them exposed to the risk of safety accidents, and therefore hinders their independent living. In this regard, the importance of desirable residential environment has emerged. Some preceding studies have addressed the characteristics of disabled people's residential environment plan; however, the information on what environmental benefits are offered through such characteristics is insufficient. This study aims to analyze the housing design guidelines for disabled people in respect of the benefit of disabled people who are actual users. In this study, essential design guidelines for disabled people verified through expert workshop panel was analyzed based on user benefit theory. According to the study results, the total guidelines have the most characteristics supporting behavioral facilitation, and mainly consist of physiological maintenance characteristics related to disabled people's health and safety. Also, it is founded that environmental affordance essentially required depending on each spatial function was different. The ratio of physiological maintenance item is high in access route, unlike living room, kitchen and bed room where behavioral facilitation is especially emphasized. These findings can be utilized as basic data for customized residential environment plan to realize residential welfare for disabled people.

Building a Product Design of Innovative Strategy for Creating Enterprise Development

  • Liao, Shih-Chung
    • The Journal of Industrial Distribution & Business
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    • v.5 no.1
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    • pp.17-25
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    • 2014
  • Purpose - Nowadays, the innovative design concept is being implemented in product design. In order to satisfy market trends and the demand for quality, designers should employ customer satisfaction questionnaires and analyze them with various experimental processes. Research design, data, and methodology - These methodologies would help designers have a better understanding of their customers and judge the market size and clustering validity, by diverse product strategies, for dealing with the rapid change prevailing in the market today. Results - By considering the innovative design with regard to telephones as an experimental case, the study investigates and demonstrates how the product can benefit from market-oriented and customized management concepts, when creative design ability is utilized for developing the product. Conclusions - Along with the benefit of having an innovative product value, the product can stimulate progress inthe development of the enterprise management, which has emerged as the main issue in the area of social and economic development in every developed country.

The Stream Restoration Program Evaluation Issue (하천복원사업 평가기준의 과제)

  • Choi, Mihee
    • Journal of Environmental Impact Assessment
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    • v.15 no.1
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    • pp.13-22
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    • 2006
  • The Korean government adopted the integrated stream water management policy recently with growing perception that natural disasters and pollution in Korea have been due not only to such human factors as urbanization and industrialization, but also to the policy of functionally separated management of irrigation, flood control and ecological management. Contrary to its good intention, research result shows that it is not realistic to expect that this new integrated policy in Korea will work well. In order to be an effective policy and program evaluation, this paper suggests that evaluation indicator on related programs and projects should be made through bottom-up process. For example, environmental benefit should be taken into account rather than just economic benefit, and cultural and social characteristics in the project region should be also considered seriously.

Priority Decision of Cross-Compliance of Public-Benefit Direct Payment for Agriculture and Rural Area (농업·농촌 공익형 직불제 상호준수의무 우선순위 결정)

  • Chae, Hong-Gi;Kim, Se-Hyuk;Kim, Tae-Kyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.4
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    • pp.218-225
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    • 2020
  • This study analyzed the priorities of the cross-compliance items of public-benefit direct payment using an Analytic Hierarchy Process and Fuzzy Decision Making Analysis. The valuation criteria are policy efficiency, farm acceptability, and feasibility, and the valuation targets are the basic and additional cross-compliance items. The survey was performed by targeting 50 experts from each class, and conducted for about a month starting from the beginning of July 2019. The results show that the weight of the valuation criteria is higher in the order of farm acceptability, feasibility, and policy efficiency. Compliance with PLS standards, compliance with disposal standards of waste vinyl and pesticides, soil testing, compliance with toxic substance standards, education, etc. are comparatively evaluated to be higher cross-compliance items in basic cross-compliance. Disposing of an abandoned well, jointly collecting and disposing of agricultural by-products, common area care and cleaning, maintenance of empty houses and poor facilities, growing green manure crops during the fallow period, etc. are comparatively evaluated to be higher cross-compliance items for the additional cross-compliance. The results of this study are expected to contribute to the government's policy related to the cross-compliance of public-benefit direct payment.

User Benefit Characteristics of Universal Design Guidelines for Homes in Ireland (아일랜드 '주택을 위한 유니버설디자인 가이드라인'의 사용자 혜택 특성 연구)

  • Lee, Yeunsook;Ahn, Somi;Hyun, Jiwon;Park, Jaehyun
    • Korean Institute of Interior Design Journal
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    • v.26 no.2
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    • pp.72-82
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    • 2017
  • Current world population is rapidly ageing and the disabled population is expected to age seriously as well. The concern about the elderly and the disabled is increased largely not just the field of social welfare and service but the housing planning where the physical environment of everyday life is. Recently in Ireland, 'Universal Design Guideline for Homes' is established and proposed in public. It is considered as initial and special national policy for the socially venerable. The purpose of this research is to analyze the User Benefit Characteristics(UBC) of 'Universal Design Guideline for Homes in Ireland' and clearly organize the characteristics for comprehensive communication. The research subjects are 444 guidelines of 'Universal Design Guideline for Homes in Ireland.' The research is conducted by contents analysis technique, and each guideline is analyzed by the 4 main concepts of UBC- 'Behavioral Facilitation(BF)', 'Physiological Maintenance(PhM)', 'Perceptual Maintenance(PM)', 'Social Facilitation(SF).' As results, the User Benefit Characteristic of 'Universal Design Guideline for Homes in Ireland' is ordered by PhM>PM>BF>SF. The design guidelines are supposed to support ageing in place and sustainable living in the existing houses even though people are ageing or being disabled. 'Universal Design Guideline for Homes in Ireland' supports safe behavior and comfort cognition especially in indoor and surrounding outdoor environment. This research is significant for sharing the knowledge and comprehension of decreasing environmental stress of the elderly in specific, and could be utilized for developing new elderly housing in future.

A Study on Economic Valuation Model of Special Libraries (전문도서관 서비스의 경제적 가치평가를 위한 분석모형 개발)

  • Chung, Hye-Kyung
    • Journal of the Korean Society for information Management
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    • v.22 no.3 s.57
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    • pp.147-162
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    • 2005
  • This study aims to suggest a new approach to economic valuation of the special library, in response to the necessity of economic justification of the special library operated by firms and research institutes. Benefit measurement elements and analysis methods to be used in the study were derived through feasibility evaluation on models in previous studies, and objectivity and applicability were the criteria for feasibility evaluation. Depending on which type of resources are used in providing service, different benefit measurement elements and methods were applied. Based on this, calculation formula for service valuation of special library was presented. The development of analysis model for economic valuation of special library made it possible to objectively prove the value of the special library, and is considered to provide an opportunity to publicize the real value of the special library.

An Empirical Study on Relationship between Environmental Management and Sustainable Development (기업의 환경경영이 지속가능한 발전에 미치는 실증분석)

  • Jang, Kee-Yoon
    • Journal of Environmental Policy
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    • v.8 no.3
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    • pp.81-113
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    • 2009
  • This study conducted a regulatory impact analysis regarding the introduction of the Korean version of REACH(Registration, Evaluation and Authorization of Chemicals). The direct cost of the Korean REACH is estimated at a total of 101 billion Korean won over the 11 year period. The cost includes pre-registration, testing, registration, Chemical Safety Assessment(CSA) and Chemical Safety Report(CSR), evaluation, and the authorization costs of 15,223 chemical substances produced and imported more than 1 ton per year in Korea in 2006. With regard to the benefit, the only public health benefit is included in the estimation. Based on the available foreign and domestic data, this study estimated that the economic values of public health benefits are in the range of 33.2~138.6 billion Korean won if only the savings of the National Health Expenditures are considered and it reaches 203.9~1,640.3 billion Korean won if the willingness to pay(WTP) for disease prevention is included. This study proved that the Korean REACH passed the cost/benefit criteria. The benefit-cost ratio of the Korean REACH, however, is estimated to be lower than its EU counterpart. Thus it is suggested that a rigorous study to reduce the costs to industry be required before the Korean government introduces the Korean REACH.

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Study on the Place of Local Tax Payment: Focusing on the Local Income Tax (지방세 납세지 개편에 관한 연구: 지방소득세를 중심으로)

  • Won, Yunhi
    • Korean Journal of Legislative Studies
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    • v.27 no.1
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    • pp.157-185
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    • 2021
  • The place of local tax payment has a realistic meaning in determining the jurisdiction of local taxation. In deciding where to pay tax, the benefit principle, beyond the convenience of tax payment and the efficiency of tax collection, should be considered as the core criteria. The benefit principle seems to be well reflected in the payment place of most local taxes. However, in the case of the Local Income Tax that shares the tax base with the Income Tax, the payment places for business income and capital gains of real estate need to be changed from the place of residence to of business and real estate. Since the benefits of local governments' public services contribute to generating income through various activities such as working or conducting business, it is necessary to ensure that taxation is carried out in the benefit areas where such income activities are conducted. This reform seems to alleviate the tax imbalance among local governments to some extent, and certain positive effects are expected in the areas of tax payment and collection.