• 제목/요약/키워드: Beneficial Model

검색결과 738건 처리시간 0.02초

인체에서 식품의 기능성 확인을 위한 최신의 분석 방법 (New paradigm for human intervention study in functional food development)

  • 김지연;김민서;정세원;권오란
    • 식품과학과 산업
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    • 제51권1호
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    • pp.8-15
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    • 2018
  • Functional food research has been struggling to demonstrate their beneficial effects in human, however, the physiological changes in humans who are in the target for functional food are very subtle and long term. In addition, it is difficult to obtain significant beneficial effect because of the necessity of using relatively healthy subjects. Relatively healthy subjects are homeostatic, and most of the biomarkers maintain a certain level under the "normal" or "resting" state. Moreover, due to wide inter-individual variation, it is difficult to detect significant changes. To address this problem, research has been actively conducted to identify the efficacy of natural products using 'omics' and 'bioinformatics' technology. In this review, we would like to introduce the human intervention studies applied homeostatic challenge model.

Skin wound healing effects of (+)-syringaresinol from ginseng berry

  • Jee-hyun Hwang;Yeonsoo Kang;Heui-Jin Park;Seolyeong Kim;Su-Hyun Lee;Hangun Kim;Sang-Jip Nam;Kyung-Min Lim
    • Journal of Ginseng Research
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    • 제47권5호
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    • pp.654-661
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    • 2023
  • Background: Ginseng has been used as a traditional medicine and functional cosmetic ingredients for many years. Recent studies have focused on the potential biological effects of the ginseng berry and its ingredients. (+)-Syringaresinol (SYR) is enriched in ginseng berry and its beneficial effects on the skin have been recently reported. However, little is known about the its effects on the wound healing process of skin. Methods: Here, we evaluated the skin wound healing effect of (+)-SYR using the human fibroblast Hs68 cell and ex vivo pig and human skin tissue model. Scratch wound test and hydrogen peroxide (HPO) induce chemical wound model were employed. Results: (+)-SYR promoted the migration and proliferation of Hs68 cells without significant cytotoxicity at the tested concentrations. Especially, in ex vivo pig and human skin tissue, HPO-induced chemical wound was recovered almost completely by (+)-SYR. In line with the finding in Hs68, the protein expression levels of TGF-β and PCNA, a proliferation marker were increased, demonstrating the beneficial effects of (+)-SYR on skin wound repair. Conclusion: Collectively, we demonstrated that (+)-SYR from ginseng berry, can enhance the wound healing effect by accelerating cell proliferation and skin regeneration, suggesting the potential utility of (+)-SYR for skin wound repair.

건설 분야 전자도면의 모델 기반 교환을 위한 IFC2.x2모델의 2차원 형상정보모델의 확장 개발에 관한 기초 연구 (Development of Two Dimensional Extension Model far IFC2.x2 Model in the Construction Field)

  • 김인한;서종철
    • 한국CDE학회논문집
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    • 제10권2호
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    • pp.121-132
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    • 2005
  • There have been several efforts for the investigation of the formal development team which was formed in the IAI to develop a common 2D standard specification between ISO/STEP and IAI/IFC since 2002. As a result, a drafting model has been included in the IFC2.x2 model. However, to be used actively in the construction practice for construction drawing exchange, the IFC model should be extended to the paper space for multiple views, drawing output, and delivery of drawings. Therefore, in this paper, the methodology of relating STEP and IFC has been investigated and schema extension of paper space(drawing sheet, presentation view, view pipeline), complex entity(leader), and dimension(associative) have been achieved. The resulting, IFC model will enable a basic harmonization with KOSDIC. SCADEC, and STEP-CDS by retaining the current IFC architecture. In addition, IT systems for the construction industry can be beneficial from the developed data model.

Prediction of compressive strength of slag concrete using a blended cement hydration model

  • Wang, Xiao-Yong;Lee, Han-Seung
    • Computers and Concrete
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    • 제14권3호
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    • pp.247-262
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    • 2014
  • Partial replacement of Portland cement by slag can reduce the energy consumption and $CO_2$ emission therefore is beneficial to circular economy and sustainable development. Compressive strength is the most important engineering property of concrete. This paper presents a numerical procedure to predict the development of compressive strength of slag blended concrete. This numerical procedure starts with a kinetic hydration model for cement-slag blends by considering the production of calcium hydroxide in cement hydration and its consumption in slag reactions. Reaction degrees of cement slag are obtained as accompanied results from the hydration model. Gel-space ratio of hardening slag blended concrete is determined using reaction degrees of cement and slag, mixing proportions of concrete, and volume stoichiometries of cement hydration and slag reaction. Furthermore, the development of compressive strength is evaluated through Powers' gel-space ratio theory considering the contributions of cement hydration and slag reaction. The proposed model is verified through experimental data on concrete with different water-to-binder ratios and slag substitution ratios.

Ice forces acting on towed ship in level ice with straight drift. Part I: Analysis of model test data

  • Zhou, Li;Chuang, Zhenju;Ji, Chunyan
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제10권1호
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    • pp.60-68
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    • 2018
  • A series of tests in an ice tank was carried out using a model-scale ship to investigate the ice loading process. The ship model Uikku was mounted on a rigid carriage and towed through a level ice field in the ice tank of the Marine Technology Group at Aalto University. The carriage speed and ice thickness were varied. In this paper, ice loading process was described and the corresponding ice forces on the horizontal plane were analysed. A new method is proposed to decompose different ice force components from the total ice forces measured in the model tests. This analysis method is beneficial to understanding contributions of each force component and modelling of ice loading on hulls. The analysed experimental results could be used for comparison with further numerical simulations.

RESEARCH ON SENTIMENT ANALYSIS METHOD BASED ON WEIBO COMMENTS

  • Li, Zhong-Shi;He, Lin;Guo, Wei-Jie;Jin, Zhe-Zhi
    • East Asian mathematical journal
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    • 제37권5호
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    • pp.599-612
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    • 2021
  • In China, Weibo is one of the social platforms with more users. It has the characteristics of fast information transmission and wide coverage. People can comment on a certain event on Weibo to express their emotions and attitudes. Judging the emotional tendency of users' comments is not only beneficial to the monitoring of the management department, but also has very high application value for rumor suppression, public opinion guidance, and marketing. This paper proposes a two-input Adaboost model based on TextCNN and BiLSTM. Use the TextCNN model that can perform local feature extraction and the BiLSTM model that can perform global feature extraction to process comment data in parallel. Finally, the classification results of the two models are fused through the improved Adaboost algorithm to improve the accuracy of text classification.

On the comparison of mean object size in M/G/1/PS model and M/BP/1 model for web service

  • Lee, Yongjin
    • International Journal of Internet, Broadcasting and Communication
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    • 제14권3호
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    • pp.1-7
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    • 2022
  • This paper aims to compare the mean object size of M/G/1/PS model with that of M/BP/1 model used in the web service. The mean object size is one of important measure to control and manage web service economically. M/G/1/PS model utilizes the processor sharing in which CPU rotates in round-robin order giving time quantum to multiple tasks. M/BP/1 model uses the Bounded Pareto distribution to describe the web service according to file size. We may infer that the mean waiting latencies of M/G/1/PS and M/BP/1 model are equal to the mean waiting latency of the deterministic model using the round robin scheduling with the time quantum. Based on the inference, we can find the mean object size of M/G/1/PS model and M/BP/1 model, respectively. Numerical experiments show that when the system load is smaller than the medium, the mean object sizes of the M/G/1/PS model and the M/BP/1 model become the same. In particular, when the shaping parameter is 1.5 and the lower and upper bound of the file size is small in the M/BP/1 model, the mean object sizes of M/G/1/PS model and M/BP/1 model are the same. These results confirm that it is beneficial to use a small file size in a web service.

LISREL을 이용한 주거환경 평가 측정모델 개발 -대전시 저소득층을 대상으로- (The Development of Measurement Model for Evaluation of Residential Environment in Low Income Families by LISREL Program)

  • 최목화
    • 대한가정학회지
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    • 제33권4호
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    • pp.157-172
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    • 1995
  • The purpose of this study was to develop a measurement model for evaluation of residential environment in low-income families. Residential environment means the housing unit itself and neighborhoods and community characteristics. Based on the previous research on housing environment, six factors (comfortable environment in indoor and outdoor, facilities environment in complex and community, sociopsychological environment, management and economic environment) were selected to evaluate residential environment and to provided a foundation for exploring the multidimensional factors of this research. As s confirmatory study, an Analysis of Linear Structural Relationships(LISREL) was utilized to develop the model. Despite of some measurement errors, the goodness of fit of an overall model was acceptable. Facilities environment in complex and sociopsychological environment were the most important factors in residential environmental evaluation of the low income families. the findings showed that housing policies and programs to improve the quality of homes in low-income families seemed to be beneficial to improve residential satisfaction of the residents.

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프로세스 분석을 위한 IDEF3 모델을 CPM Network 모델로 변환하기 위한 절차 (Procedures of Transform IDEF3 Model into CPM Precedence Network Model for Process Analysis)

  • 강동진;김경표;이상용;정용식
    • 한국산업정보학회:학술대회논문집
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    • 한국산업정보학회 1999년도 춘계학술대회 발표논문집
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    • pp.135-144
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    • 1999
  • A major concern in Concurrent Engineering is the control and management of workload in a period of process. As a general rule, leveling the peak of workload in a certain period is difficult because concurrent processing is comprised of various processes, including overlapping, paralleling and looping. Therefore, workload management with resource constraints is so beneficial that effective methods to analyze design process This study presents a procedure to transform the IDEF3 process model into the precedence logic network model for more useful assessment of the process. This approach is expected to facilitate resolving resource constrained scheduling problems more systematically in Concurrent Engineering environment.

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Generalization of shear truss model to the case of SFRC beams with stirrups

  • Colajanni, Piero;Recupero, Antonino;Spinella, Nino
    • Computers and Concrete
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    • 제9권3호
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    • pp.227-244
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    • 2012
  • A theoretical model for shear strength evaluation of fibrous concrete beams reinforced with stirrups is proposed. The formulation is founded on the theory of plasticity and the stress field concepts, generalizing a known plastic model for calculating the bearing capacity of reinforced concrete beams, to the case of fibrous concrete. The beneficial effect of steel fibres is estimated taking into account the residual tensile strength of fibrous concrete, by modifying an analytical constitutive law which presents a plastic plateau as a post-peak branch. Around fifty results of experimental tests carried out on steel fibrous concrete beams available in the literature were collected, and a comparison of shear strength estimation provided by other semi-empirical models is performed, proving that the numerical values obtained with the proposed model are in very good agreement with the experimental results.