• 한국지역지리학회지
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• 제15권4호
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• pp.510-523
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• 2009

Geodemographics(GD)는 지리적 패턴 분석을 위해 사회경제적, 행태적 자료의 이용에 관한 연구 기법으로써 동일한 근린 혹은 이웃한 지역에 거주하는 사람들은 유사한 인구적, 행태적 특성을 보인다는 전제를 바탕으로 유사한 지역을 도출하고 그 지역들의 공간적 특징을 유형화하는 연구 방법이다. 따라서 본 연구는 이러한 GD 개념의 활용성과 지역 유형화의 유용성을 확인하기 위하여 서울시 행정등 및 관련 인구 센서스 자료를 바탕으로 서울시 지역 유형화에 대한 연구를 진행하였다. 본 연구는 Ward와 K-means 및 관련 통계 기법에 의한 센서스 변수들의 표준화와 군집화를 통해 총 13개의 사회경제적 특성을 공유하는 지역을 도출하고 이를 바탕으로 서울시 13개 각각의 지역에 대한 지리적 성격을 제시하였다. 마지막으로 본 연구에서는 GD의 분석기법이 유사한 공간적 성격을 갖는 새로운 공간 단위 및 군집을 탐색하고 유형 화하는데 효과적인 공간기법이 될 수 있음을 제시하고자 하였다.

• 대한조현병학회지
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• 제24권1호
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• pp.26-35
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• 2021

Objectives: Social function deficit is known as a core feature of schizophrenia. This study aimed to investigate differences in empathic tendencies and theory of mind (ToM) skills between healthy controls and young individuals with schizophrenia, and to examine the associations between empathic tendencies, ToM skills and schizotypy, and executive function in schizophrenia. Methods: Thirty patients with schizophrenia and 30 healthy controls were enrolled and assessed using the interpersonal relationship index (IRI; perspective taking, fantasy, empathic concern, and personal distress subscales), ToM-Picture Story Task (ToM-PST; sequence and cognitive questionnaire), Wisconsin schizotypy scale (revised physical anhedonia and perceptual aberration), and Stroop tests for empathic tendencies, ToM skills, schizotypy, and executive function. Results: In individuals with schizophrenia, the IRI for perspective taking and ToM-PST score for cognitive function were lower, and the IRI for personal distress was higher than those in healthy controls. The IRIs for perspective taking and fantasy were related to revised physical anhedonia, and that for empathic concern was associated with revised physical anhedonia and perceptual aberration. The ToM-PST score for sequence was associated with the Stroop test score for schizophrenia. Conclusion: These findings indicate deficits in empathic tendencies and ToM skills, which may be independently and primarily associated with schizotypy and executive function in young individuals with schizophrenia.

• Journal of Nutrition and Health
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• 제55권1호
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• pp.188-199
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• 2022

본 연구 결과, 상하이와 안후이성 지역에 거주하는 중국 성인에서 인지된 행동통제력은 과거 건강한 식행동 경험과 관계없이 건강한 식행동의 장단기 행동 의도에 대한 잠재적 결정요인으로 관찰되었다. 이러한 결과는 급변하는 경제 발전 중에서 만성질환 예방을 위해 건강한 식행동의 중요성을 강조하고 있는 중국에서 성인들의 건강한 식행동을 도울 수 있는 근거자료로 활용될 수 있을 것이다. 향후 중국 내 다양한 인구집단에서의 추가 연구나 대규모 조사연구 및 건강한 식행동을 위한 개인의 인지된 행동통제력을 강화하는 영양 중재나 영양교육 등에 본 연구결과가 의미있는 기초자료가 되기를 기대한다.

• Journal of Korean Neurosurgical Society
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• 제66권5호
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• pp.511-524
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• 2023

Objective : This animal model aimed to compare the rat group that received brain irradiation and did not receive additional treatment (only saline) and the rat group that underwent brain irradiation and received Granulocyte colony stimulating factor (G-CSF) treatment. In addition, the effects of G-CSF on brain functions were examined by magnetic resonance (MR) imaging and histopathologically. Methods : This study used 24 female Wistar albino rats. Drug administration (saline or G-CSF) was started at the beginning of the study and continued for 15 days after whole-brain radiotherapy (WBRT). WBRT was given on day 7 of the start of the study. At the end of 15 days, the behavioral tests, including the three-chamber sociability test, open field test, and passive avoidance learning test, were done. After the behavioral test, the animals performed the MR spectroscopy procedure. At the end of the study, cervical dislocation was applied to all animals. Results : G-CSF treatment positively affected the results of the three-chamber sociability test, open-space test and passive avoidance learning test, cornu Ammonis (CA) 1, CA3, and Purkinje neuron counts, and the brain levels of brain-derived neurotrophic factor and postsynaptic density protein-95. However, G-CSF treatment reduced the glial fibrillary acidic protein immunostaining index and brain levels of malondialdehyde, tumor necrosis factor-alpha, nuclear factor kappa-B, and lactate. In addition, on MR spectroscopy, G-CSF had a reversible effect on brain lactate levels. Conclusion : In this first designed brain irradiation animal model, which evaluated G-CSF effects, we observed that G-CSF had reparative, neuroprotective and anti-neurodegenerative effects and had increased neurotrophic factor expression, neuronal counts, and morphology changes. In addition, G-CSF had a proven lactate-lowering effect in MR spectroscopy and brain materials.

• 한국치위생학회지
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• 제11권2호
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• pp.293-301
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• 2011

Objectives : The aim of the trial was to study the effect of plaque control(tooth brushing instruction) for oral health improvement on periodontitis patients. Methods : 30 patients(35~65 years) with advanced periodontal disease were subjected to a baseline examination including assessment of oral hygiene status(O'leary index), gingival condition(bleeding). the assessment were repeated after 2, 4, 6 weeks. cognitive, behavioral and clinical outcomes were assessed in the primary care setting by questionnaire and clinical oral examination. Results : The oral hygiene status expressed as the individual mean percentage of tooth surfaces with plaque 59.3% at baseline and 21.2% after 6 weeks(p<0.001). The gingival bleeding status expressed as the individual mean point of interdental papilla 3.8 at baseline and 1.9 after 6 weeks(p<0.001). Also, the patients self-assessment about correct tooth brushing behavior was 3.9(5-point likert scales), satisfaction of plan practices 4.1(5-point likert scales), efficacy of tooth brushing instruction 8.7(10-point likert scales). Patients wanted to continuous participation. Conclusions : A verification of effect after individualized oral health instruction and repeated dental plaque control represented to significance on plaque control score, oral care practice and oral health recognition. The important oral care step against periodontal disease is to establish good oral health habits. Also, oral health behavior recognition is more important for the practice of oral health. Therefore professional plaque control and tooth brushing instruction absolutely need in improving oral health.

• 한국지역지리학회지
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• 제16권5호
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• pp.610-622
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• 2010

미국에서 과체중과 비만은 최근까지 지속적으로 증가하고 있다. 그러나 과체중과 비만을 일으키는 요인에 대한 연구에 비해 이들 현상이 갖는 공간적 분포, 즉 공간의존성과 이질성에 대한 연구는 미미한 실정이다. 이에 본 연구는 과체중과 비만, 그리고 위험요인(고혈압과 당뇨병) 사이의 공간적 분포를 분석하였다. Moran''s I와 Geary''s C 분석 결과, 비만은 공간적으로 무작위 분포를 갖고 있지만, 저체중 정상 과체중은 공간적 유사성을 지니고 있음을 확인할 수 있었다. 또한 일반최소자승법에 의한 선형 회귀분석과 잔차도분석을 통해 고혈압과 당뇨는 비만과 공간적 의존성을 갖는 것으로 파악할 수 있었다.

• Journal of Acupuncture Research
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• 제23권3호
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• pp.103-115
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• 2006

Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disease associated with aging in the human population. This disease is characterized by the following 4 structural changes : Atrophy of the Cortex, Parasympathetic, and other neural cells, the existence of Neurofibrillary tangles (NFTs), and the accumulation of Senile plaques. NFTs and Senile plaques is known to be the index of this disease. Senile plaques disturbs the neutro transmission and depletes of Acetylcholine. So, Recovery of Acetylcholine is the primal objective for treating Alzheimer's disease. So, Inhibiting the activity of Acetylcholine Esterase (AChE), which causes the hydrolysus of acetylcholine into choline and acetate, can be seen as a key role for treating Alzheimer's disease. Increasing body of evidence has been demonstrated that Bee Venom Acupuncture (BV) could compete with complex protein involving in multiple step of $NF-_{\kappa}B$ activation and exert the anti -inflammatory potential of combined inhibition of the prostanoid and nitric oxide synthesis systems by inhibition of IKK and $NF-_{\kappa}B$. The effect of BV through behavioral tests after memory impairment induced by Scopolamine. We examined the improving effect of BV on the Scopolamine (1 mg/Kg, i.p.)-induced memorial impairment using passive avoidance response and water maze tests in the mice. BV (0.84, $1.67\;{\mu}g/ml$) reversed the Scopolamine-induced memorial impairment in dose dependent manner. This study therefore suggests that BV acupuncture method may be useful for prevention of development or progression of AD.

• 응용통계연구
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• 제21권2호
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• pp.211-219
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• 2008

고객 로열티는 한 회사가 지속적으로 수익을 계속 창출하기 위해 매우 중요한 요소이다. 특히 카드사는 멤버쉽(Membership)에 가입한 회원 및 가맹점과의 고객 관계 관리(Customer Relationship Management: CRM)가 무척 강조되는 업종이기에 카드사에서 고객 로열티는 더욱 더 중요하게 다루어지고 있다. 본 연구에서는 A카드사의 로열티스코어 개발 사례를 다루고자 한다. A카드사에서는 이해하기 쉽고 활용하기 쉬운 모델 개발을 목적으로 카드업종의 특성을 반영 한 로열티 스코어를 개발하고자 하였다. 본 연구에서 제안하는 로열티 스코어 모델은 반응변수에 개별 변수 별 로짓모형을 적용하고 이들 모형에서 얻어진 카이제곱 적합도 통계량을 가중치로 고려하는 방법이다. 본 연구에서 제안한 모델은 모델에 대한 안정성 평가 결과 시간의 흐름에 따라 매우 안정된 결과를 보인다.

• Nutrition Research and Practice
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• 제10권2호
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• pp.221-228
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• 2016

BACKGROUND/OBJECTIVES: This study measured the effects of a taste education program developed in Korea on food neophobia and willingness to try novel foods in school children. SUBJECTS/METHODS: One-hundred and twenty school children (aged 7-9 years) residing in Seoul participated in 12 sessions of a taste education program for 3 months. The Korean taste education program was adapted from "Les classes du gout" by J. Puisais and modified to suit a Korean education environment. The study subjected school children to pre- and post-programs on food neophobia and willingness to try novel foods (WTNF), in addition to children's food neophobia in their parents. A total of 101 survey data were analyzed using SPSS 18.0. RESULTS: Regarding the effects of taste education, scores of food neophobia significantly decreased (P < 0.01) in the posttest, mean (m) score ($4.10{\pm}1.19$) decreased compared to the pretest ($4.39{\pm}1.00$), and WTNF significantly increased (P < 0.001) in the pretest (m) score ($0.48{\pm}0.33$) compared to the pretest ($0.32{\pm}0.34$). This result indicates verification of the study hypothesis. CONCLUSIONS: Food neophobia scale (FNS), an index that measures personal food preference [1,2], showed a very weak correlation with behavioral willingness to taste novel foods (WTNF). Therefore, it is expected that the two scales measure different things. However, considering that the traits of food neophobia are not easily changed, the taste education program was administered in a remarkably effective manner.

• 한국산학기술학회논문지
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• 제15권6호
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• pp.3706-3713
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• 2014

본 연구의 목적은 성인 근로자의 치주질환 유병 여부와 관련하여 인구학적, 구강 행태적 위험 요인을 알아보고자 시행하였다. 연구대상 및 방법은 제5기 3차 국민건강영양조사 자료를 활용하여 20-64세 한국 성인 근로자 1650명을 대상으로 시행하였다. 연구결과, 치주조직 유병자에 대해서 성별, 연령, 소득수준, 교육수준, 전신질환, 수면시간, 구강건강수준, 씹기 문제 및 저작 불편함이 위험요인으로 나타났다. 이중 가장 많은 영향력은 씹기 문제와 저작불편에 문제가 있는 근로자에서 3.5배 이상 치주조직병에 이환될 가능성이 높게 나타났다. 본 연구 결과를 통해서 한국 근로자에 있어서 치주질환 유병의 다양한 위험요인이 존재하고 있음 알 수 있었으며, 향후 치주질환의 유병율을 줄이기 위해서는 정기적인 구강검진과 건강검진, 충분한 수면을 취하고 스트레스를 낮추어야 할 뿐만 아니라, 소득수준과 교육수준의 차이와 같은 사회경제적 불평등 해결을 위한 제도적인 노력이 필요할 것으로 보인다.