• 인터넷정보학회논문지
• /
• 제15권6호
• /
• pp.99-106
• /
• 2014

최근 자연어 및 정형언어 처리, 인공지능 알고리즘 등을 활용한 효율적인 의미 기반 지식모델의 생성과 분석 방법이 제시되고 있다. 이러한 의미 기반 지식모델은 효율적 의사결정트리(Decision Making Tree)와 특정 상황에 대한 체계적인 문제해결(Problem Solving) 경로 분석에 활용된다. 특히 다양한 복잡계 및 사회 연계망 분석에 있어 정적 지표 생성과 회귀 분석, 행위적 모델을 통한 추이분석, 거시예측을 지원하는 모의실험 모형의 기반이 된다. 하지만 대부분의 지식 모델은 특정 지표나 정제된 데이터를 수동적으로 모델링하여 분석에 활용한다. 본 논문에서는 텍스트 마이닝 기술을 통해 방대한 비정형 정보로부터 지식 모델을 구성하는 토픽인자와 관계 노드를 생성하고 이를 통합하는 방법과 정형적 알고리즘을 제시한다. 이를 위해 먼저, 텍스트 마이닝을 통해 도출되는 키워드 맵을 동치적 지식맵으로 변환하고 이를 의미적 지식모델로 통합하는 방법을 설명한다. 또한 키워드 맵으로부터 유의미한 토픽 맵을 투영하는 방법과 의미적 동치 모델을 유도하는 알고리즘을 제안한다.

• Toxicological Research
• /
• 제24권2호
• /
• pp.137-150
• /
• 2008

Sexually mature male and female rats were orally intubated with the organophosphorus insecticide, Pestban at a daily dosage of 7.45 or 3.72 mg/kg bwt, equivalent to 1/20 and 1/40 $LD_{50}$, respectively. Male rats were exposed for 70 days, while the female rats were exposed for 14 days, premating, during mating and throughout the whole length of gestation and lactation periods till weaning. The results showed depressed acetylcholinesterase(AChE) activity in the brain of parents, fetuses and their placentae in a dose-dependent manner. The fertility was significantly reduced with increasing the dose in both treated groups, with more pronounced suppressive effects in the male treated group. The number of implantation sites and viable fetuses were significantly reduced in pregnant females of both treated groups. However, the number of resorptions, dead fetuses, and pre-and postimplantation losses were significantly increased. The incidence of resorptions was more pronounced in treated female compared to male group and was dose dependant. The behavioral responses as well as fetal survival and viability indices were altered in both treated groups during the lactation period. The incidence of these effects was more pronounced in the treated female group and occurred in a dose-related manner. The recorded morphological, visceral, and skeletal anomalies were significantly increased with increasing the dose in fetuses of both treated groups, with more pronounced effects on fetuses of treated females. In conclusion, the exposure of adult male and female rats to Pestban would cause adverse effects on fertility and reproduction.

• Toxicological Research
• /
• 제24권3호
• /
• pp.207-212
• /
• 2008

Pesticide residues play several key roles as environmental and food pollutants and it is crucial to develop a method for the rapid determination of pesticide residues in environments. In this study, a simple, effective, and sensitive method has been developed for the quantitative analysis of methoxyfenozide in water and soil when kept under laboratory conditions. The content of methoxyfenozide in water and soil was analyzed by first purifying the compound through liquid-liquid extraction and partitioning followed by florisil gel filtration. Upon the completion of the purification step the residual levels were monitored through high performance liquid chromatography(HPLC) using a UV absorbance detector. The average recoveries of methoxyfenozide from three replicates spiked at two different concentrations and were ranged from 83.5% to 110.3% and from 98.1% to 102.8% in water and soil, respectively. The limits of detection(LODs) and limits of quantitation(LOQs) were 0.004 vs. 0.012 ppm and 0.008 vs. 0.024 ppm, respectively. The method was successfully applied to evaluate the behavioral fate of a 21% wettable powder(WP) methoxyfenozide throughout the course of 14 days. A first-order model was found to accurately fit the dissipation of methoxyfenozide in water with and a $DT_{50}$ value of 3.03 days was calculated from the fit. This result indicates that methoxyfenozide dissipates rapidly and does not accumulate in water.

• 한국강구조학회 논문집
• /
• 제23권1호
• /
• pp.61-72
• /
• 2011

본 연구에서는 일체식교대 강교량 거더-교대 연결부의 강체거동 및 균열저항성능의 향상을 위한 구조상세를 제시하고 그에 따른 연결부의 거동을 실험적으로 평가하였다. 거더-교대 연결부의 강체거동 및 균열저항성능을 향상시키기 위하여 전단연결재 및 tie bar를 적용한 연결부를 제시하였으며, 제시된 연결부 실험체와 기존 시공경험에 의해 설계된 연결부 실험체의 하중재하실험을 통하여 연결부의 성능 및 거동 특성을 검토하였다. 하중재하실험 결과, 모든 강 거더-교대 연결부 실험체들은 목표 설계하중 및 항복하중 이하에서 충분한 강성 및 균열저항 성능을 보여 강 거더-교대 연결부로 적용 가능하다. 하지만 실험체의 초기 강성, 균열의 진전형상 측면, 하중-변형률 측면에서 전단연결재와 tie bar가 적용된 강 거더-교대 연결부가 기존에 적용되어 왔던 강 거더-교대 연결부에 비하여 구조적으로 우수한 것으로 판단된다.

• 한국사회복지학
• /
• 제57권2호
• /
• pp.321-350
• /
• 2005

본 연구는 보호관찰 여성 클라이언트를 대상으로 약물남용 재발예방을 목적으로 하는 프로그램을 개발하고 운영한 결과를 제시하고 있다. 본 연구가 개발한 프로그램은 인지적 행동적 대처능력의 증진과 지지적 환경의 구축 및 활용을 강조하였다. 또한 집단구성원들이 모두 여성인 점을 고려하여 여성관련 이슈를 다루는 내용을 프로그램에 포함시켰다. 프로그램은 서울보호관찰소에서 2003년 가을부터 1년여 동안 3차례에 걸쳐 운영되었으며 그 결과는 긍정적으로 나타났다. 즉 본 프로그램을 통해 프로그램 참가자의 약물사용에 대한 태도는 부정적으로 변화되었고, 약물사용과 관련된 다양한 상황에 직면했을 때 약물사용을 거절할 수 있는 능력이 강화된 것으로 분석되었다. 국내에서는 약물남용 여성만으로 구성된 집단을 운영하고 더욱이 이를 평가한 경우가 거의 전무하기 때문에 본 연구는 국내의 약물남용 관련 연구자 및 실무자들에게 연구와 실천을 위한 새로운 자극을 제공하는 의의가 있다고 판단된다.

• 보건교육건강증진학회지
• /
• 제28권5호
• /
• pp.145-160
• /
• 2011

Objectives: This study attempted to apply the Intervention mapping and Transtheoretical models to develop a program to promote moderate alcohol drinking in university students. Methods: Surveyed data from 1,137 university students were analyzed to identify personal and environmental determinants for alcohol drinking. Based on these determinants, program objectives were established. Crossing the objectives with related important determinants resulted in matrices of learning objectives for which educational strategies were developed. Subsequently, an intervention program were designed to achieve those objectives. Results: Identified personal determinants included awareness, attitudes, self-efficacy and behavioral skills. Environmental determinants were binge drinking behaviors of family members and peers, and social pressure for drinking. Program, impact and learning objectives were developed to change the identified determinants. Program activities included provision of information on positive and negative consequences of binge drinking, opportunities for assessing one's drinking pattern, increasing outcome expectancies of and skill building for monitoring drinking, resisting peer pressure and managing stress. To facilitate adoption and maintenance of the program, an intervention diffusion plan was suggested. An evaluation plan was developed by utilizing RE-AIM framework. Conclusions: In order to expand evidence bases for effective theory-based programs, the developed program should be tested in diverse university settings.

• Asian Pacific Journal of Cancer Prevention
• /
• 제17권12호
• /
• pp.5159-5164
• /
• 2016

Objective: The dynamics of morbidity, disability and death rates due to malignant neoplasms in the population in Uralsk city of the Republic of Kazakhstan were studied for 2011-2015, with a focus on age and sex, as well as tumor location. Methods: Statistics for total morbidity, primary disability and mortality from cancer in the adult population of the city of Uralsk for 2011-2015 were calculated per 100 thousand. Estimation of morbidity was based on data from form - $N{\underline{o}}12$ ${\ll}$Report on the number of diseases registered in patients living in the area of health care organizations and patient population under medical observation". Evaluation of primary disability was based on form $N{\underline{o}}7$ ${\ll}$The distribution of newly recognized disabled by disease class, age, sex and disability groups" for 2011-2015 in Ural city and analysis of cancer was carried out using annual form 7 "Report on the sick, and diseases of malignant neoplasms". Result: The most common localizations of cancer were the trachea, bronchi, lungs, stomach and mammary glands. High death rates were noted for patients with cancer of the trachea, bronchi, lung, as compared to stomach and esophagus. Conclusion: The results of our investigation and data in the literature indicate that regional characteristics influence the impact of risk factors associated with cancer. An unfavorable environmental background contributes to ill health of urban populations, contributing to development of cancer. Moreover behavioral risk factors are very important, such as smoking, alcohol drinking, and an unhealthy diet. All these factors require urgent adoption of a package of measures for prevention, early detection and timely treatment. Detailed study of cancer is necessary to develop national programs and activities for prevention and control.

• 성인간호학회지
• /
• 제27권6호
• /
• pp.665-672
• /
• 2015

Purpose: The aims of current study were to assess the inhaler competency and medication adherence, and to identify association of inhaler competency with medication adherence in patients with obstructive lung disease. Methods: We did a secondary analysis of the Hanyang Obstructive Pulmonary Evaluation data in a single institution from June 2014 to April 2015 after an approval of Institutional Review Board. A total of 150 patients with asthma or chronic obstructive lung disease participated in the study. Inhaler competency was evaluated accuracy in each step for using metered dose inhaler. Medication adherence was calculated using actually dispensed doses based on the prescribed inhaler doses. Results: Older adults (${\geq}65$) had lower competency in using inhaler (66.7 vs 83.3, z=-4.52, p<.001) and poorer medication adherence (67.7 vs 91.8, $x^2=14.06$, p<.001) than adults (<65). Inhaler competency was associated with medication adherence (p=.26, p=.001). Surprisingly, more than 50% of patients were current smokers. Conclusion: Inhaler competency and medication adherence were lower in older adults with obstructive lung disease than those in adult-age patients. Therefore, an individual education program for older patients should be developed to improve the rates of proper use of inhalers. Nursing management for obstructive lung disease should focus on developing behavioral intervention strategies for smoking cessation.

• Asian Pacific Journal of Cancer Prevention
• /
• 제17권7호
• /
• pp.3505-3510
• /
• 2016

Cervical cancer is a major public health problem in Thailand, being ranked second only to breast cancer. Thai women have been reported to have a low rate of cervical cancer screening (27.7% of the 80% goal of WHO). We therefore aimed to apply the social marketing theory and health belief model in promoting cervical cancer screening in Kanthararom District, Sisaket Province. A total of 92 from 974 targeted women aged 30-60 years were randomly divided into two groups. The experimental group underwent application of social marketing theory and a health belief model program promoting cervical cancer screening while the control group received normal services. Two research tools were used: (1) application of social marketing theory and health belief model program and (2) questionnaire used to evaluate perceptions of cervical cancer. Descriptive and inferential statistics including paired sample t-test and independent t-test were used to analyze the data. After the program had been used, the mean score of perception of cervical cancer of experimental group was at a higher level (${\bar{x}}=4.09$; S.D.=0.30), than in the control group (${\bar{x}}=3.82$; S.D.=0.20) with statistical significance (p<0.001). This research demonstrated an appropriate communication process in behavioral modification to prevent cervical cancer. It can be recommended that this program featuring social marketing and the health belief model be used to promote cervical cancer screening in targeted women and it can be promoted as a guideline for other health services, especially in health promotion and disease prevention.

• International Journal of Contents
• /
• 제8권1호
• /
• pp.74-81
• /
• 2012

The aim is to investigate the analgesic effect of transcranial direct current stimulation(tDCS) on central neuropathic pain(CNP) in spinal cord contusive rat model. Twenty Sprague-Dawley rats($250{\pm}50$ g, male) were used. Thoracic spinal cord(T10) was contused using New York University(NYU) spinal cord impactor. The animals were randomly assigned to two groups; GroupI: Non-treatment after SCI induction(n=10), GroupII: application of tDCS(0.1 mA, 20 min/time, 2 times/day, 5 days/6week) after SCI induction(n=10). Assess the effect of tDCS using the Basso Beattie Bresnahan(BBB) locomotor rating scales, Touch $test^{TM}$ sensory evaluator(TTSE), Plantar test$^{\circledR}$after contusion at the $2^{nd}$, $3^{rd}$, $4^{th}$, $5^{th}$, $6^{th}$ week and the immunohistochemistric response of c-fos in the thalamus, cerebral cortex after contusion at the $3^{rd}$, $6^{th}$ week after SCI. The scores of BBB scales were significantly different from $3^{rd}$week. TTSE were different significantly over time, but there were no differences at each evaluation times on between-measure time effects. Plantar test were different significantly over time and there were difference at the $4^{th}$, $6^{th}$ week after SCI on between-measure time effects. Also, immunohistochemistric response of c-fos was reduced significantly from $3^{rd}$, $6^{th}$ week after SCI in tDCS group compared with control group in thalamus and cortex. These results identified that tDCS of non-invasive therapeutic method may have beneficial analgesic effect on CNP after SCI with behavioral test and immunohistochemical test.