• Biomolecules & Therapeutics
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• v.27 no.2
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• pp.168-177
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• 2019

Dysregulation of excitatory neurotransmission has been implicated in the pathogenesis of neuropsychiatric disorders. Pharmacological inhibition of N-methyl-D-aspartate (NMDA) receptors is widely used to model neurobehavioral pathologies and underlying mechanisms. There is ample evidence that overstimulation of NMDA-dependent neurotransmission may induce neurobehavioral abnormalities, such as repetitive behaviors and hypersensitization to nociception and cognitive disruption, pharmacological modeling using NMDA has been limited due to the induction of neurotoxicity and blood brain barrier breakdown, especially in young animals. In this study, we examined the effects of intraperitoneal NMDA-administration on nociceptive and repetitive behaviors in ICR mice. Intraperitoneal injection of NMDA induced repetitive grooming and tail biting/licking behaviors in a dose- and age-dependent manner. Nociceptive and repetitive behaviors were more prominent in juvenile mice than adult mice. We did not observe extensive blood brain barrier breakdown or neuronal cell death after peritoneal injection of NMDA, indicating limited neurotoxic effects despite a significant increase in NMDA concentration in the cerebrospinal fluid. These findings suggest that the observed behavioral changes were not mediated by general NMDA toxicity. In the hot plate test, we found that the latency of paw licking and jumping decreased in the NMDA-exposed mice especially in the 75 mg/kg group, suggesting increased nociceptive sensitivity in NMDA-treated animals. Repetitive behaviors and increased pain sensitivity are often comorbid in psychiatric disorders (e.g., autism spectrum disorder). Therefore, the behavioral characteristics of intraperitoneal NMDA-administered mice described herein may be valuable for studying the mechanisms underlying relevant disorders and screening candidate therapeutic molecules.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.6
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• pp.1101-1112
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• 2021

Organizations continue to increase investment in information security(IS) policies and technologies to prevent external intrusion and internal exposure to information assets. However, as the organization's regulations and behavioral requirements for strict IS policy increase, employees may induce negative behaviors through IS-related stress. The purpose of this study is to suggest the effects of challenge and hindrance stressors on IS compliance intentions and to confirm how authentic leadership moderates the positive and negative effects of stressors. We reflected employees of the organization who are applying IS policy to their work as a study target and applied a survey to obtain a sample for research hypothesis verification. As a result of analysis through structural equation modeling, challenge and hindrance stressors affected IS compliance intentions, and authentic leadership moderated the effects of stressors on compliance intention. Our research helps to establish insiders support strategies to achieve internal IS goals, because the results suggested stressor conditions and leaders' behavioral directions that influence employees IS compliance behavior.

• Fashion & Textile Research Journal
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• v.23 no.2
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• pp.200-211
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• 2021

This study examines the effects of fashion influencers' body types (realistic versus ideal body types) on self-expression, self-representation, and recommendation intentions, as mediated by familiarity toward influencers. Although fashion influencers lead to a positive consumer response compared to traditional advertisements, previous research on the effects of fashion influencers on consumers is limited. Thus, this study tests the role of consumers' socio-psychological aspects in understanding how and why fashion influencers affect consumers' behavioral intentions associated with self-expression, self-representation, and influencer recommendation. A total of 180 women in their 20s and 30s participated in the survey. The responses were collected after showing them stimuli featuring fashion influencers with either ideal or realistic body shapes. The data were analyzed using SPSS18.0 for descriptive statistics, and AMOS 18.0 for confirmatory factor analysis and structural equation modeling. The results showed that participants who were shown realistic body types perceived familiarity, which generated positive effects on self-expression, self-representation, and recommendation intentions. Hence, the effects of influencers' body types on recommendation intention are mediated by familiarity. Self-expression and self-representation intentions also increase influencer recommendation intention. Comparatively, participants who were shown ideal body types only induced higher self-representation intention, which increased their recommendation intention. The current findings can help fashion marketers select the appropriate influencers who fit their target customers as promotional models, as well as to induce changes in consumers' behavioral intention.

• Journal of the Korean Geotechnical Society
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• v.38 no.9
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• pp.53-67
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• 2022

Micropiles are cast-in-place-type piles with small diameters. They are widely used for the foundation reinforcement of existing buildings and structures because this technique is easy to construct and economic. A base expansion structure is developed following the mechanism of radial expansion at the pile tip under compression. Numerical analysis, durability tests, and centrifuge tests have been conducted using the base expansion structure. In this study, three-dimensional numerical modeling was performed to describe the behavioral mechanism of the base expansion structure using steel bar penetration under compressive loading, and numerical analyses using centrifuge test conditions were performed for the comparative studies. Additionally, the base structure was modified based on the results of lab-scale analyses, and the bearing capacities of micropiles were compared using field-scale numerical analyses under various ground conditions.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.6
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• pp.777-784
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• 2017

In the architectural space, the user's behavior is the most important factor in evaluating the quality of architecture. Normally, the evaluation of user behavioral performance was carried out after a building was completed. Recently, interest in and efforts at pre-simulation based on information technology are accelerating. However, since existing user simulation technology is concerned mainly with simply escaping from a large space, it is impossible to simulate the behavior of multiple users in an architectural space. The present study strives to develop a human-figured intelligent agent for advanced user simulation based on ontology. The main purpose of the study is to employ the intelligent behaviors of a NPC(Non-player Character) to infer the ontology of both spatial and user information. In this paper, we intend to integrate ontology inference technology into the virtual space. And also, this study suggest the ontology visualization technology which illustrate the ontology-based information and their change in the spatial information.

• 한국체육학회지인문사회과학편
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• v.55 no.5
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• pp.117-125
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• 2016

Most of health behavioral research were conducted with only individual psychological variables. The purpose of this study was to integrate the theory of planned behavior and social ecological model to explain exercise intention through multilateral approaches. 50s male 252 exercise participants were used in the final data analysis. Reliability analysis, confirmatory factor analysis, correlation analysis, structural equation modeling were used to analyze. The results indicated that physical environment has a positive influence on the subjective norm. Attitude, subjective norm and perceived behavioral control have positive influence on intention. Lastly, Social environment has a positive influence on the attitude. According to the results of this study, it will be able to contribute to integration of theoretical model for various health behavior and also help to develop intervention for physical activity promotion.

• Korean Journal of Biological Psychiatry
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• v.30 no.1
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• pp.17-23
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• 2023

Objectives This study aims to develop valid experimental models for depression through chronic reserpine exposure to zebrafish (Danio rerio). Methods The effect of chronic reserpine on zebrafish behavior in the novel tank was examined. Changes of gene expression on telencephalon were also investigated. Results Chronic reserpine (40 mg/L, 7 days) induced overt behavioral effects, but markedly reduced activity, resembling motor retardation in depression. In telencephalon of zebrafish, gene expression associated with monoamine oxidase and norepinephrine transporter was decreased. Expression of serotonin transporter gene was increased. Conclusions Our results show that the pharmacological model of depression in zebrafish can induce not only behavioral changes, but also monoamine changes in the homology of human mood regulation centers.

• The Korean Journal of Franchise Management
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• v.9 no.2
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• pp.17-29
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• 2018

Purpose - The environment surrounding the franchise industry in recent years is a big threat to the franchise business. In this perspective, this study examines the effect of franchise CEO's Innovation, CSR Passion, and customer orientation(CO) on customers' perceived service quality(PSQ), affection, and commitments in the context of food-service franchise industry. This study suggests the guidelines on how franchisor uses their passion and customer orientation on customer to maintain and increase the commitments. Research design, data, and methodology - In order to achieve these purposes, research model and hypotheses were developed. Out of 500 respondents received through online survey, 449 respondents were used, because of 51 incomplete respondents. The data were analyzed using frequency analysis, confirmatory factor analysis, correlation analysis, and structural equational modeling with SPSS 23.0 and AMOS 23.0 statistical program. Result - The results of the study are as follows. First, innovation passion has a significant impact on PSQ and customer affection. And CSR passion have a significant impact on PSQ. Second, customer orientation has a significant impact on PSQ and customer affection. Third, PSQ has a significant impact on customer affection and sustainable commitment. Fourth, customer affection has a significant impact on behavioral commitment. Fifth, behavioral commitment has a significant impacts on sustainable commitment. Conclusions - The implications of this study are following as: Restaurants franchisor and CEOs should have a passion for innovation to continuously identify consumer needs and develop new menus and services that meet their needs. Second, franchisor and CEOs need to demonstrate the importance of creating the right environment, creating a fair business, and trying to create products in a given environment. Finally, franchisor and CEOs should demonstrate how to build relationships with customers and how to maintain positive feelings. In addition, it is necessary to appeal to the customers with enthusiasm and a customer-oriented tendency of the entrepreneur of the franchise head office in order to maintain the relationship with the customer and feelings.

• Journal of Korean Library and Information Science Society
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• v.43 no.1
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• pp.261-285
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• 2012

The purpose of this study is to confirm that the user benefit criteria can be applied as the user benefit criteria of children's libraries by examining the theoretical validity of the user benefit criteria and furthermore, by clarifying and verifying the mutual relation between the user benefit criteria and the child development area. For such a purpose, this study collected data from 247 users of children's libraries in the country and collected data was analyzed using the structural equation modeling. The result of analysis is as follows. First, the relation between physical development and behavioral facilitation, emotional development and physiological maintenance, cognitive development and perceptual maintenance, and the development of social skills and social facilitation was appropriate. Second, usability, safety and diversity was valid as an index of behavioral facilitation, self-esteem, amenity and peacefulness was valid as an index of physiological maintenance, esthetic sense, dynamics and flexibility was valid as an index of perceptual maintenance, and leisure, communication and territoriality was valid as an index of social facilitation. Third, children who prefer physical development prefer the benefit of behavioral facilitation, children who prefer emotional development prefer the benefit of physiological maintenance, children who prefer cognitive development prefer the benefit of perceptual maintenance and children who prefer the development of social skills prefer the benefit of social facilitation.

• Journal of Distribution Science
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• v.13 no.4
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• pp.65-76
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• 2015

Purpose - This article aims to present and test a model regarding franchisors' supporting activities that may positively influence franchisees' attitude toward the franchising headquarter and their own business performance. Moreover, the authors examine the moderating effect of competitive intensity between franchisee attitude and business performance. Most previous research focused on behavioral performance measurements such as satisfaction, trust, and commitment. There are few empirical studies that focus on financial performance data because it is difficult to determine a relational mechanism between behavioral and financial performance. Moreover, financial data is confidential and difficult to collect in many cases. However, this study measures financial performance (e.g., sales revenue per square meter) differently than most previous research, which is mostly focused on the behavioral performance measurements. Research design, data, and methodology - To test our hypotheses, we selected 137 franchisee managers who are running chains of one of the foremost bakery franchise brands in South Korea. This study carefully investigated the reliability, content validity, convergent validity, and discriminant validity of the proposed instrument by analyzing the data obtained from the samples. The data was analyzed using the AMOS structural equation modeling program. Results - The results indicated that: non-financial support activities (e.g., information exchange and communication) had a positive impact on the franchisee attitude toward the franchising headquarter. The franchisee attitude in turn had a positive effect on the headquarters' business performance. Furthermore, competitive intensity could enhance the relationship between franchisee attitude toward franchising headquarter and business performance in a local franchise market. However, financial support activities (e.g., rewards and promotional support) and training had no relationship with either franchisee attitude or business performance. Conclusions - This study provides some practical implications to franchisors in terms of franchise operation and store opening strategies. With respect to the franchise operation strategy, franchisors need to focus on non-financial rather than financial support. Most franchisees consider the necessity of financial support activities and not their sufficiency because these activities are specified in their franchise contract. In addition, it is important for franchisees to maintain a positive attitude for the franchise headquarters. The franchisees with a positive attitude for the franchisor can show a high degree of solidarity for various support activities, and it consequently determines franchisees' sales performance. In terms of franchise store opening strategy, this study suggests an additional criterion that can be considered in determining the location of direct and non-direct management stores (e.g., franchisees' stores). In this research, franchise stores located within high level of competitive intensity are shown to have a high relationship between franchisee attitudes of franchisor support activities and business performance compared to the franchisees located within low competitive intensity level. This result shows that opening non-direct franchise stores is more effective than direct stores in higher competitive market situations. Research contribution, implications, and further research directions are discussed at the end of the paper.