• Biomolecules & Therapeutics
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• 제8권2호
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• pp.199-205
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• 2000

On the inter-order protoplast fusants of Lentinus edodes and Ganoderma lucidum was the antitumor activity test performed and the fusant P22 was selected. The hot water extract of the cultured mycelia of P22 were purified by DEAE-cellulose chromatographya and the resulting purified fraction was designated as P22A. It was found to be a proteoglycan whose molecular weight was 47 kDa. When examined for immunopotentiation activity, P22A increased the number of colony forming unit in the bone marrow stem cells to 3-folds. It also potentiated the secretion of nitric oxide in activated macrophages to 2-folds. In humoral immune response, it increased the activities of the alkaline phosphatase in differentiated B cells to 1.6-folds and the number of plaque forming cells to 1.8-folds. In cellular immune response, it restored the depressed response of delayed type hypersensitivity in tumor bearing mice to normal level. These results suggest that P22A have potential to restore the decreased immune activity of the tumor bearing mice to normal level.

• 한국농공학회지
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• 제11권3호
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• pp.1707-1718
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• 1969

The purpose of this experiment is to determine the relations between numbers, arrangements and pumping rates of wells. In this experiment, well pipes were vertically set up in an artificial water-bearing sand layer of homogeneous quality. Wells were arranged in different ways and their number was varied in order to observe the variation of pumping rates. Sands were filled in a square tank, $183cm{\times}91.5cm{\times}91.5cm$ so as to secure a water-bearing layer. Water was constantly supplied from a supply tank located at an end of the tank. The number of well pipes was varied from one to four. Well pipes were connected by a horizontal header pipes were connected by a horizontal header pipe located above them and one pump was used. Pumping rates were measured, when they were arranged in longitudinal and lateral directions, They were also arranged in a square and triangle. The main results thus obtained are presented as follows: (1) When well pipes are laid out in a longitudinal line, i. e., in a flow direction, the ratios of pumping rates of one-pipe well and wells 2-, 3- and 4- pipe t, are 1.903, 2.506 and 2.66, respectively. (2) When well pipes are laid out in a lateral line, i.e., in a perpendicular direction to flow, the same ratios as (1) are 1.912, 2.527 and 2.88. (3) When four pipes are laid out in a square and three pipes are laid out in a triangle, pumping rates are deereased, Comparing with the cases when pipes are laid out in a straight line.

• Journal of Advanced Marine Engineering and Technology
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• 제7권1호
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• pp.49-63
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• 1983

Coupled transverse shaft vibrations have become the target of great concern in high powered ships such as container ships. Due to increasing ship's dimensions and high propulsive power, resonance frequencies of the propeller shaft system tend to decrease and can appear in some cases within the operating speed range of engine. In this connection, the coupled free transverse vibrations of shaft system in two planes are theoretically investigated. This shaft system carries a number of discs and is flexibly supported by a number of bearing stiffness are considered for the calculation. Transfer matrix method is applied to calculate the shaft responses in both planes. A digital computer program is developed to calculate the shaft responses of the coupled transverse vibrations in two planes. An experimental model shaft system is made. It is composed of a disc, shafts, ball bearings thrust bearings and flexible bearing supports. The shaft system is excited by an electrical magnet, and shaft vibration responses in two planes are measured with the strain gage system. From these measurements, the natural frequencies of the shaft system in both planes are found out. The developed program is also used to calculate the shaft vibration responses of experimental model shaft system. From the results of these calculations, the natural frequencies of shaft system in two planes are derived. Theoretical predictions of model shaft natural frequencies show good agreements with its esperimental measurements.

• Structural Engineering and Mechanics
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• 제55권3호
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• pp.461-472
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• 2015

The existence of initial imperfections in manufacturing or assembly of double-layer space structures having hundreds or thousands of members is inevitable. Many of the imperfections, such as the initial curvature of the members and residual stresses in members, are all random in nature. In this paper, the probabilistic effect of initial curvature imperfections in the load bearing capacity of double-layer grid space structures with different types of supports have been investigated. First, for the initial curvature imperfection of each member, a random number is generated from a gamma distribution. Then, by employing the same probabilistic model, the imperfections are randomly distributed amongst the members of the structure. Afterwards, the collapse behavior and the ultimate bearing capacity of the structure are determined by using nonlinear push down analysis and this procedure is frequently repeated. Ultimately, based on the maximum values of bearing capacity acquired from the analysis of different samples, structure's reliability is obtained by using Monte Carlo simulation method. The results show the sensitivity of the collapse behavior of double-layer grid space structures to the random distribution of initial imperfections and supports type.

• 콘크리트학회논문집
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• 제18권1호
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• pp.135-145
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• 2006

In high multistory reinforced concrete buildings, coupled shear walls can provide an efficient structural system to resist horizontal force due to wind and seismic effects. Coupled shear walls are usually built over the whole height of the building and re laid out either as a series of walls coupled by beams and/or slabs or a central core structure with openings to accommodate doors, elevators walls, windows and corridors. A number of recent studies have focused on examining the seismic response of concrete, steel, and composite coupling beams. However, since no specific equations are available for computing the bearing strength of steel coupling beam-wall connections, it is necessary to develop such strength equations. There were carried out analytical and experimental studies to develop the strength equations of steel coupling beam-connections. Experiments were conducted to determine the factors influencing the bearing strength of the steel coupling beam-wall connection. The results of the proposed equations were in good agreement with both test results and other test data from the literature. Finally, this paper provides background for design guidelines that include a design model to calculate the bearing strength of steel coupling beam-wall connections.

• 대한기계학회논문집A
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• 제33권11호
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• pp.1217-1224
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• 2009

This paper presents a finite element (FE) analysis of the torsional rigidity of a two-stage cycloid drive. The cycloid disk makes contact with a number of pin-rollers simultaneously and eccentric shafts transmit not only torque of the spur gear stage to the cycloid disk, but also that of the cycloid disk to the output disk. Contacts between the disk and pin-rollers are simplified as linear spring elements, and the bearing of eccentric shaft is modeled as a rigid ring that has frictional contact to the disk and an elastic support. FE analysis for an ideal solid cycloid drive was performed and verified by a theoretical calculation. Accurate contact forces were then estimated by iterating between FE analysis for contact forces and Hertz theory calculations for nonlinear contact stiffness. In addition, torsional rigidity of the cycloid drive is analyzed to show that the bearing and nonlinear Hertz contact theory should be considered in analysis and design of a cycloid drive, which was verified with experiments. Finally, the effects of contact stiffness, bearing stiffness and cycloid disk structural stiffness according to the cycloid disk rotation on the torsional rigidity were investigated.

• Structural Engineering and Mechanics
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• 제71권3호
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• pp.211-221
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• 2019

To study the eccentric compression behavior of ultra-high performance fiber reinforced concrete (UHPFRC) columns, six UHPFRC columns and one high-strength concrete (HSC) column were tested. Variation parameters include load eccentricity, volume of steel fibers and stirrup ratio. The crack pattern, failure mode, bearing capacity, and deformation of the specimens were studied. The results showed that the UHPFRC columns had different failure modes. The large eccentric compression failure mode was the longitudinal tensile reinforcements yielded and many horizontal cracks appeared in the tension zone. The small eccentric compression failure mode was the longitudinal compressive reinforcements yielded and vertical cracks appeared in the compressive zone. Because of the bridging effect of steel fibers, the number of cracks significantly increased, and the width of cracks decreased. The load-deflection curves of the UHPFRC columns showed gradually descending without sudden dropping, indicating that the specimens had better deformation. The finite element (FE) analysis was performed to stimulate the damage process of the specimens with monotonic loading. The concrete damaged plasticity (CDP) model was adopted to characterize the behaviour of UHPFRC. The contribution of the UHPFRC tensile strength was considered in the bearing capacity, and the theoretical calculation formulas were derived. The theoretical calculation results were consistent with the test results. This research can provide the experimental and theoretical basis for UHPFRC columns in engineering applications.

• 한국기계가공학회지
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• 제17권6호
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• pp.75-82
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• 2018

This study suggests an optimal design process of an LMU, which is installed on the top side of offshore structures. The LMU is consist of EB(elastomeric bearing) and steel plate, and supports the vertical loads of offshore structures and assists its stable installation. The structural design requirement of the LMU is related to its stiffness. This study utilizes the finite element analysis to predict the stiffness. The stiffness of the EB depends on the size of the bearing. Thus, the design variables in this study are defined as the thickness, the width and the number of plates. Since the LMU has different loads for different locations, its stiffness should be designed differently. The multiobjective function is introduced to attain the target stiffness. In this process, the metamodel using the kriging interpolation method is adopted to replace the true stiffness.

• 한국지진공학회논문집
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• 제23권1호
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• pp.9-18
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• 2019

In 2017 Pohang Earthquake, a number of residential buildings with pilotis at their first level were severely damaged. In this study, the results of an analytical investigation on the seismic performance and structural damage of two bearing wall buildings with pilotis are presented. The vibration mode and lateral force-resisting mechanism of the buildings with vertical and plan irregularity were investigated through elastic analysis. Then, based on the investigations, methods of nonlinear modeling for walls and columns at the piloti level were proposed. By performing nonlinear static and dynamic analyses, structural damages of the walls and columns at the piloti level under 2017 Pohang Earthquake were predicted. The results show that the area and arrangement of walls in the piloti level significantly affected the seismic safety of the buildings. Initially, the lateral resistance of the piloti story was dominated mainly by the walls resisting in-plane shear. After shear cracking and yielding of the walls, the columns showing double-curvature flexural behavior contributed significantly to the residual strength and ductility.

• 한국산림과학회지
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• 제107권3호
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• pp.287-293
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• 2018

본 연구는 본격적인 목재수확시기에 대응하여 대형화되어 가는 목재운송차량의 원활한 통행과 노체 피해 방지를 위해 산림기술경영연구소 관내 연약지반을 대상으로 토목섬유를 활용한 노반 조성 후 시간경과에 따른 노면지지력 변화와 대형 목재운송차량의 통행 횟수 증가에 따른 노면지지력 및 침하량 변화를 분석하였다. 그 결과, 노반 조성구간의 경우 약 1년의 시간경과 후 노면지지력이 양호판정기준인 CBR 15% 이상으로 안정화 되어 가는 것으로 나타났으며, 토목섬유별 처리효과는 큰 차이를 보이지 않는 것으로 나타났다. 또한 노반 조성구간에서 대형 목재운송차량의 통행이 최대 300회 이루어진 이후에는 침하량이 허용기준 50 mm 이하로 안정되고, 노면지지력 또한 CBR 20% 이상으로 향상되는 것으로 나타났으며 노반의 두께별로는 큰 차이를 보이지 않았다. 그러나 토목섬유를 활용한 노반을 조성하지 않은 구간에서는 허용기준 이상의 침하와 함께 노면의 지지력은 대형 목재운송차량의 통행이 불가능한 것으로 나타났다. 따라서 대형목재운송차량의 통행을 위한 연약지반의 노면지지력 보강을 위해서는 토목섬유를 부설하고 노반을 최소 0.2 m 이상 조성하는 것이 필요하다.