• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.317-317
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• 2022

Seakso 5, a maize hybrid, was applied for variety in 2021 by Gangwon Agricultural Research and Extension Services in Korea. This variety was bred to produce a purple extract of com husk. It shows purple color in the husk and cob and contains abundant anthocyanins. In this study, to obtain basic data on purple com 'Seakso 5' husk extract (PCHE), a husk extract was prepared and the contents of vitamins, amino acids and fatty acids were analyzed. The Seakso 5 husks were extracted with 30% alcohol and concentrated, after adding dextrin to the concentrate, it was spray-dried to prepare an extract. The PCHE were analyzed for vitamins, amino acids, and fatty acids by referring to the Food Code. As a result, three types of vitamins were detected, and their contents were vitamin B₁ 0.14 mg/100g, vitamin B₂ 2.30 mg/100g, and vitamin C 11.32 mg/100g. A total of 15 amino acids were detected in the PCHE, including aspartic acid and glutamic acid, and the content of aspartic acid was the highest at 3.02 mg/g. Simultaneous analysis of fatty acids Among 37 types, saturated fatty acids were palmitic acid (C16:0), stearic acid (C18:0), monounsaturated fatty acids were oleic acid (C18:1(n-9)), polyunsaturated fatty acids were linoleic acid(C18:2(n-6)c) and a-Linolenic Acid (C18:3(n-3)) were detected. Among the detected fatty acids, the content of palmitic acid was the highest at 40.75 mg/100g. In the future, These analysis results will be used as reference data for temporary food ingredient applications by the Ministry of Food and Drug Safety.

• Journal of Korean Medical classics
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• v.37 no.2
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• pp.101-119
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• 2024

Objectives : This study examined the characteristics of famine relief and fasting formulas in Korean Medical Texts from early Joseon to early modern period. Methods : In addition to previous studies and texts, basic materials were collected from various academic database such as the Korean Medical Classics Database, Korean History Database, Chinese Text Project, Weijiwenku, etc., then analyzed. Results : In Korean Medicine from the early Joseon to early modern Korea, there was a strong awareness to use fasting prescriptions which were applied in Daosim for the purpose of famine relief, using both medicinals and common food ingredients together as complex prescriptions rather than single ingredient formulas. Famine relief and fasting formulas were continuously listed in many medical texts published after the Donguibogam, in modified or newly improved forms. Moreover, the food ingredients and medicinals used in these formulas were consisted of those which could be easily found in the famished nation of the time. Many of these formulas were tried and tested prescriptions, frequently used in clinical settings. Most of the ingredients and medicinals used in the famine relief and fasting formulas were sweet, bland, and neutral in nature, supporting Qi circulation and tonifying the Spleen and Stomach. Therefore in times of famine, these medicinals could help prevent digestive problems and decline of stamina. Conclusions : Research and contemporary interpretation on the famine relief and fasting formulas could contribute to not only health management but to relieving nutrition imbalance and famine, expanding the field of Korean Medicine application.

• Journal of Digestive Cancer Research
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• v.11 no.2
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• pp.104-107
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• 2023

The Ministry of Health and Welfare of Korea has implemented various social security programs to ensure a basic standard of living and raise overall quality of life for all citizens. The Korean social security system provides social insurance, public assistance, and social welfare services. To achieve adequate drug benefits, the Drug Management Department of Health Insurance Review and Assessment Service (HIRA) implement drug management duties including drug listing, upper price limit setting, scope of benefits, and post-factum management. When a manufacturer or an importer wants to apply for National Health Insurance (NHI) coverage of the drug that has obtained safety and efficacy approval, the pharmaceutical benefit assessment committee of HIRA evaluates the drug's clinical efficacy and cost-effectiveness to determine whether or not to include the drug into the benefit package. The benefit standards for a listed drug (ingredient) are set either for the whole permitted range or a part of range with conditions. To increase the coverage rate for new drugs, the listed drugs are regularly reviewed for their value. The status of listed drugs can be adjusted or eliminated from the benefit package if the clinical efficacy turns out to be insignificant. Therefore, through these pharmaceutical management procedures, high-quality drugs are provided at reasonable prices, which save healthcare expenditure by price determination and selective coverage in consideration of economic evaluation.

• Journal of Conservation Science
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• v.35 no.2
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• pp.177-186
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• 2019

A Termiticide that is applied to the soil treatment method, one of the methods for preventing termites in Korea's wooden cultural properties, will be subjected to the leaching of the effective ingredient in treated soil by the moisture behavior of rain. As a result, termiticide is deteriorated and needs to be reprocessed, but the standards and evaluation methods are nonexistent in korea. Accordingly, a basic indoor evaluation measure was proposed for the evaluation of the effectiveness of the termiticide chamber and the calculation of the reprocessing period. First, avoidance and contact toxicity were assessed at two concentrations of the same termiticide as a method for assessing termiticide suitability. The evaluation of mortality revealed that the soil termiticide used in this experiment was non-repellent, and that death from contact was confirmed. Afterwards, artificial rainfall and soil penetration tests were conducted to determine efficacy of termiticide in soil and the approximate reprocessing period was calculated by comparing the weather data. Persistence evaluation revealed perforation by termites after continuous water exposure of more than about 160 to 170mm of water injection condition. Based on the results, compared with weather data for the last five years, the termiticide of concentration used in this experiment is expected to remain effective for about one year if treated after September. The purpose of this study was to provide basic data for the establishment of a manual for the selection of termiticide for soil treatment by calculating the efficacy for termite mortality and the duration of the leaching effectiveness by water behavior in soil.

• Journal of Life Science
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• v.22 no.9
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• pp.1224-1230
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• 2012

Cancer chemotherapy drugs command a large share of the market, and the development of new therapeutics with high efficacy and specificity is an active area of study. Recently, the development of cancer therapeutics from natural products targeting angiogenesis has drawn attention due to conventional chemotherapeutics showing serious side effects and resistance in cancer cells. In this study, we investigated the pharmacological efficacy of Gomisin A, an active ingredient of Schizandra chinensis baillon, on tumor growth and metastasis. Administration of Gomisin A at 10 and 100 ${\mu}g/ml$ reduced tumor growth in vivo by $80.5{\pm}8.1%$ and $96.2{\pm}2%$, respectively, compared with positive tumor controls. Treatment of Gomisin A in normal and various tumor cell lines did not exert significant toxicity. Mice treated with Gomisin A at a concentration of 10 and 100 ${\mu}g$/head showed a significant reduction in tumor-induced angiogenesis of $151{\pm}16.9%$ and $98.5{\pm}29.5%$, respectively. Furthermore, tumor metastasis analysis revealed that the administration of Gomisin A at a concentration of 10 and 100 ${\mu}g$/head inhibited tumor metastasis by $13.5{\pm}8.56%$ and $58.3{\pm}9.12%$, respectively. In addition, Gomisin A significantly decreased cell adhesion of the B16BL6 cells to the extracellular matrix. These results demonstrate that Gomisin A inhibits tumor growth via suppression of angiogenesis and tumor metastasis inhibition, without cellular toxicity. The pharmacological efficacy of Gomisin A suggests that it may be a potential candidate for the development of cancer drugs.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.11
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• pp.1766-1773
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• 2014

The purpose of this research was to scrutinize dieticians' perspective of seafood ingredients prices in school food-service. Suppliers' contract status, seafood ingredient usage and satisfaction, expectations regarding prices of seafood ingredients, and willingness to pay when HACCP is taken into account were studied. Through random sampling, the survey was conducted on 231 dieticians in 11 different educational districts and 12 elementary, six middle, and three high schools. Ultimately, 142 survey responses were taken into account. Data analysis was performed using SPSS v15.0 by descriptive analysis, ${\chi}^2$-test, and t-test. For contracts regarding seafood ingredients, competitive contracts composed 79.7%. Exactly 42.1% responded that contracts were breached, and 60.1% testified that product returns were due to excessive glazing of ingredients. The satisfaction rate of 'hygiene & sanitation of product' was the highest, whereas 'price of product' was the lowest. For 'recontracting intention', 'informal purchasing' showed higher rates compared to 'competitive bidding'. Reflecting upon the six main price factors, 'designation and maintenance of HACCP', 'price of raw seafood ingredients', 'processing costs', 'margin', 'logistic costs', and 'cost of standardizing seafood ingredients', dieticians' perceived 'impact on the anticipated price' on total cost was lower than present counterparts. This implicates that 'impact on the present price' of the six price factors is too excessive, suggesting that many dieticians are unsatisfied with the current prices of seafood ingredients. Furthermore, 52.8% of dieticians stated that the maximum additional payment of HACCP seafood ingredients should be less than 5%. Consequently, this research serves as basic information for reasonable pricing of seafood ingredients and contributes to increased seafood usage by school food-services.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.10
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• pp.1326-1333
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• 2007

For preparing the basic ingredients of Gomtang-like products from the extracts of salmon frame, the extraction conditions of salmon frame were examined, and the characteristics of the extracts were compared with commercial Gomtang. Based on the crude protein, Ex-N and sensory attributes, the extractions were optimized by extracting pretreated-salmon frame in 12 times (v/w) of water for 12 hrs, before filtering with cheese cloth to yield 3 times the volume of the raw material. The concentrations of heavy metals in extracts from salmon frame were below the safety limits suggested by KFDA. The mai or amino acids were glutamic acid and aspartic acid as the free amino acids, and glycine, proline, and glutamic acid as the total amino acids. The calcium and phosphorus contents were 18.0 mg/100 mL and 33.1 mg/100 mL, respectively, and they accounted for 20% and 18% of the recommended daily allowance for mineral intake. The angiotensin I converting enzyme (ACE) inhibitory activity was improved by incubation with Flavourzyme for 4 hrs and its $IC_{50}$ was 2 mg/mL. The results above suggested that the enzymatic hydrolysates from extracts of salmon frame could be used as a basic ingredient for preparing Gomtang-like products.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.2
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• pp.171-177
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• 2014

Purpose: The present study was conducted to investigate whether the elution of the dyes from the circle contact lenses existed or not when rubbed with cotton swab. Methods: The change of lens surface was observed by scanning electron microscope when a total of seven kinds of circle contact lens were rubbed with cotton swab, and the dye elution was further compared when the lenses were soaked in multi-purpose solution in $20^{\circ}C$ and $36.5^{\circ}C$ for a week. Results: Five of a total of 7 circle contact lenses showed the dye elution from the front or the back surface of the lens when rubbed with cotton swabs, and existence of dye elution was varied depending on the type of contact lenses and different at the front and back surface even in the same lens. The tear-off of the pigmented portion by the rubbing was found through scanning electron microscopic observation when the dye elution existed. However, the dye was not eluted when the circle contact lenses was soaked in a multi-purpose solution in $20^{\circ}C$ or $36.5^{\circ}C$ for a week. Ingredient of colorant was not provided by the manufacturers in more than 50% of the circle contact lenses investigated for this study and the basic information such as the pigmentation method was provided inappropriately. Conclusions: In this study, the result was the dye elution from circle contact lenses was obtained when a physical force is applied thus, it may appear to contribute the development of circle contact lenses and safety of lens wear.

• Korean Journal of Environmental Agriculture
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• v.16 no.1
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• pp.72-79
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• 1997

Adsorption, leaching, and retention of the Flupyrazofos(KH-502), a new active ingredient for insecticide, in the soils under laborarory and field conditions were investigated to provide the basic data for the safety use and to assess a secondary impact of this insecticide on soil and water environments. A significant power function relation was found between the adsorbed KH-502 and time, representing that 45% of the added KH-502 was adsorbed within 30 min. but a quasiequilibrium was reached after 6 to 12 hr with a slower adsorption. Adsorption phenomena followed th first-order kinetics and time required for 50% adsorption was 5.8 hr. The equilibrium adsorption isotherm was explained by the Freundlich equation and was classified as S-type. The amounts of KH-502 leached through the soil column (C) as compared to initial conc. ($C_0$) were very low and these relative concentrations ($C/C_0$) were 0.073 and 0.017 in SL and CL soils, respectively. The residual conc. of KH-502 in the surface soil was comparatively low and decreased with time. Half-lives of KH-502 in the surface soil was comparatively low and decreased with time. Half-lives of KH-502 under the field conditions were estimated to be 20 and 18 days in the SL and CL soils, respectively. The KH-502 cone, transported to the subsurface soils was extremely low. These results demonstrate that KH-502 has a low pollution risk potential to the surrounding environment as far as it is used following the recommended guideline.

• Journal of the Korea Organic Resources Recycling Association
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• v.9 no.4
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• pp.117-124
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• 2001

This study was executed for utilizing it as basic data in appropriate recycling way and design by examining and analyzing various characteristics of food waste which is being discharged from various restaurant and apartment house. In general, there were differences in restaurants classification and Japanese restaurant showed big differences as compared to other restaurants. Vegetable had the highest composition and its contents had big difference according to seasons. In alien substances, oyster shells were the highest and restaurants showed high rate of alien substances than apartments, therefore it was required to divide them in advance. Salinity was the highest in Japanese restaurants and most restaurants had rate of up to 1%, so it was not appropriate for recycling. However, it was considered that if there is cleaning operation in the whole process, there might not be a problem. Feed Ingredient had 28% of fiber, 25% of protein, and 11% of fats. We analyzed noxious germs and heavy metal too. However microorganisms of etiological cause were not detected and each harmful material showed less values of control concentration. In the result of analysis of each characteristic, it is required to consider collection rate from restaurants and apartments and seasonal cause into design regarding recycling. And apartments are compatible to compost than feed and food waste from Chinese, flour restaurant and collective feeding facilities are compatible for feed, as it is evaluated.