• Journal of Periodontal and Implant Science
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• v.26 no.2
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• pp.414-428
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• 1996

The use of basic fibroblast growth factor which function as potent biologic mediators regulating numerous activities of wound healing has been suggested for the promotion of periodontal regeneration. The mitogenic effects of basic fibroblast growth factor on human periodontal ligament cells and human gingival fibroblasts were evaluated by determining the incorporation of 5-Bromo-2'deoxy-uridine into DNA of the cells in a dose -dependent manner. The cells which were prepared were the primary cultured gingival fibroblasts and periodontal ligament cells from human the fourth or sixth subpassages were used in the experiments. The cells which were seeded DMEM contain 10% FBS. The added concentrations of basic fibroblast growth factor were 0.1, 1, 10, 50, $l00{\eta}g/ml$ and basic fibroblast growth factor were added to the quiescent cells for 24 hours, 48 hours and 72 hours. They were labeled with $10{\mu}l/200{\mu}l$ 5Bromo-2'-deoxy-uridine for the last 6 hours of each culture. The results of the five determinants were presented as mean and S.D.. The results were as follows. : The DNA synthetic activity of human gingival fibroblasts was increased dose dependently by basic fibroblast growth factor at 24 hours, 48 hours and 72 hours. The similar mitogenic effects were at the 24 and 48 hours of basic fibroblast growth factor, but the DNA synthetic activity of human gingival fibroblasts generally decreased at 72 hours. The DNA synthetic activity of human periodontal ligament cells was increased dose dependently to $50{\eta}g/ml$ by basic fibroblast growth factor at 24, 48 and 72 hours, but the DNA synthetic activity decreased at $l00{\eta}g/ml$ of each hour. Generally the maximum mitogenic effects were at the 48 hours application of basic fibroblast growth factor. The DNA synthetic activity of human periodontal ligament cells generally decreased lower at 72 hours than at 24, 48 hours the application of basic fibroblast growth factor. In the comparison of DNA synthetic activity between human gingival fibroblasts and human periodontal ligament cells, human periodontal ligament cells had slightly higher proliferation activity than human gingival fibroblasts for a longer time at the high dosage of the basic fibroblast growth factor.In conclusion, basic fibroblast growth factor have important roles in the stimulation of DNA synthesis in human periodontal ligament cells and human gingival fibroblasts, and thus may be useful for clinical applications in periodontal regenerative procedures.

• Bulletin of the Korean Chemical Society
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• v.28 no.9
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• pp.1613-1614
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• 2007

• Journal of The Korean Radiological Technologist Association
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• v.25 no.1
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• pp.317-323
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• 1999

The response of endothelial cells to ionizing radiation is thought to be an important factor in the overall response of normal tissue. It has been reported that basic fibroblast growth factor (bFGF), a potent mitogen for endothelial cells, protects endoth

• Bulletin of the Korean Chemical Society
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• v.26 no.11
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• pp.1823-1825
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• 2005

Angiogenesis is tightly regulated by a variety of angiogenic activators and inhibitors. Disruption of the balanced angiogenesis leads to the progress of diseases such as cancer, rheumatoid arthritis, and diabetic blindness. Even though a number of proteins involved in angiogenesis have been identified so far, more protein factors remain to be identified due to complexity of the process. Here I report that pituitary tumor-transforming gene (PTTG) induces migration and tube formation of human umbilical vein endothelial cells (HUVECs). High levels of both vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are detected in conditioned medium obtained from cells transfected with PTTG expression plasmid. Taken together, these results suggest that PTTG is an angiogenic factor that induces production of both VEGF and bFGF.

• Korean Journal of Mathematics
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• v.5 no.2
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• pp.119-125
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• 1997

We show that there exists an isomorphism between the basic construction $(M_f)_1$ for $N_f{\subset}M_f$ and the reduction $(M_1)_f$ of the basic construction $M_1$ for $N{\subset}M$, where $f$ is a nontrivial projection in N. For a nontrivial projection $f{\in}N^{\prime}{\cap}M$ we give the basic construction $(M_f)_1$ for $N_f{\subset}M_f$ and compare it with $(M_1)_f$.

• Journal of Fashion Business
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• v.9 no.5
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• pp.37-50
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• 2005

The purpose of this study is to present basic data that can express beautiful silhouette by studying visual effect that depend on waist position of basic pants and the change of round belt width and analyzing the study of visual effect of the pattern design as well as the effect of design component. The stimuli are 21 samples: 7 variations of the location of the waistline and 3 variations of the width of the belt. The data has been obtained from 35 fashion design majors. The data has analyzed by frequency, factor analysis, anova, scheffe's test and the MCA method. The visual effects by the location of waistline and the width of belt are composed of 3 factors : horizontal direction factor, vertical direction factor and flexuosity factor. In these factors, horizontal factor is estimated by most important factor. Visual effect is positive when belt width widens as the location of waist line goes down to position of low belt. And in case the location of waist line is in the position of natural waist belt and low rise belt, belt of 3.2cm width is effective visually. The interaction effects between the location of the waistline and the width of the belt have significant differences in all factors. Factor that appears in visual effect of basic pants can be evaluated differently according to pattern of pants and characteristic of body shape. So we may receive better visual assessment if we consider the location of waist belt and width of belt in side of visual effect and image, when we produce pants giving variety to crotch depth.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.28 no.3
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• pp.10-17
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• 2005

In this paper, the life cycle assessment(LCA) methodology is applied to Personal Computer's basic materials in order to analyze the impact to the environment. LCA data collection is carried out taking into account on main materials of PC's parts and component. And the impact assessment is the environmental burden on three factor into air emission(CO2, SOx, NOx), five factor into water emission(BOD, COD, SS, N, P), and three factor on transported substance(cl, NH4, SO4). According to the result, the environmental burden of PC's basic materials was proved to be used total energy 6,285Mj and emitted CO2 259.8kg, SOx 3,571g, NOx 330g, COD 1,328g, P 246g, N 2,434g. And this paper was presented the problems of its disposition-incinerating, landfill, and recycling.

• Wind and Structures
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• v.37 no.2
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• pp.117-131
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• 2023

Korea Design Standard (KDS) will be updated with two major revisions on the assessment of wind load and performance-based wind design (PBWD). Major changes on the wind load assessment are the wind load factor and basic wind speed. Wind load factor in KDS is reduced from 1.3 to 1, and mean recurrence interval (MRI) for basic wind speed increases from 100 years to 500 years considering the reduction of wind load factor. Additional modification is made including pressure coefficient, torsional moment coefficient and spectrum, and aeroelastic instability. Combined effect of the updates of KDS code on the assessment of wind load is discussed with the case study on the specified sites and building. PBWD is newly added in KDS code to consider the cases with various target performance, vortex-induced vibration, aeroelastic instability, or inelastic behavior. Proposed methods and target performance for PBWD in KDS code are introduced.

• Bulletin of the Korean Chemical Society
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• v.27 no.9
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• pp.1456-1458
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• 2006

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.608-608
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• 2003