• 제목/요약/키워드: Baseline profile

검색결과 121건 처리시간 0.032초

A Retrospection on Foundation Design of Taipei 101

  • Chin, Chung-Tien;Chao, Hsiao-Chou;Chang, Der-Wen
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2009년도 세계 도시지반공학 심포지엄
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    • pp.145-156
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    • 2009
  • Large diameter bored pile was selected as the foundation type for Taipei 101. The pile construction method and specific construction procedures were determined based on the results of trial installation and pile load tests. The baseline for foundation design was established using the friction versus depth characteristics of each ground layer obtained from the pile load tests. As the ground profile and depth to the top of rock formation varied significantly on this site, the pile length, bearing capacity and settlement for single pile were analyzed using the information interpreted from adjacent boreholes. The post grouting at pile tip was mandatory for pile construction. Nevertheless, it was treated as a measure reducing the influence of construction uncertainties and providing extra safety for the foundation system.

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만성 뇌졸중 환자의 시간에 따른 삼킴 기능 변화 (Dysphagia and Oral Function in Chronic Stoke Patient: 3 Months Follow up Study)

  • 임익재;고명환
    • 재활복지
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    • 제22권1호
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    • pp.141-156
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    • 2018
  • 본 연구는 2011년 1월 1일부터 2012년 12월 31일까지 대학 병원에 입원 또는 재원중인 만성 뇌졸중 환자를 대상으로 이들의 삼킴 장애 양상이 시간에 따라 변화하는지를 비교하고자 하였다. 대상자는 맨 삼킴 능력 평가(Mann Assessment Swallowing Ability)에 의해 178점 이하의 점수를 보인 삼킴 장애 환자들로 이 기간 동안 최소 2회 이상의 비디오투시조영 삼킴 검사(videofluroscopic swallowing examination)를 수행한 환자 10명 이었다. 또한 이들의 삼킴 문제를 비교하기 위해 나이와 성별을 고려한 정상 성인 8명이 대조군으로 참여하였다. 시간에 따른 삼킴 장애 및 삼킴 기능을 비교하기 위해 만성 뇌졸중 환자의 구강통과시간, 인두통과시간, 후두폐쇄유발시간, 바륨 삼킴 검사(Modified Barium Swallowing Impairment Profile: $MBSImP^{TM(c)}$) 및 기능적 구강 섭취 척도(Functional Oral Intake Scale: FOIS)를 평가하였다. 삼킴 평가는 입원 후 일주일 이내에 이루어졌으며 기초선 평가 후 3 개월이 지난 뒤 재검사되었다. 연구 결과, 기초선 평가에서 만성 뇌졸중 환자는 정상인보다 지연된 삼킴 시간을 보였다(구강통과시간; z=-3.60, p<0.001, 인두통과시간; z=-2.77, p=0.004, 후두반응시간; z=-3.56, p<0.001). 만성 뇌졸중 환자군은 3개월 이후에도 비슷한 수준의 삼킴 시간을 보여 삼킴 효율성은 개선되지 않았음을 확인하였다. 반면, $MBSImP^{TM(c)}$와 FOIS 결과에서 구강 단계의 삼킴 기능과 구강 섭취 능력이 두 시점에 따라 통계적으로 유의한 차이가 있었다($MBSImP^{TM(c)}$; z=-2.02, p=0.04, FOIS; z=-2.27, p=0.02). 3개월 후에 뇌졸중 환자는 구강 기능 및 구강 섭취 능력이 호전된 것으로 나타났으며 이는 일부 삼킴 기능이 회복되었기 때문으로 해석된다. 본 연구는 만성 뇌졸중 환자의 삼킴 장애 양상을 규명하고 호전 가능성을 살펴보았다는 점에서 의의가 있으며 만성 뇌졸중 환자의 삼킴 문제를 관리하고 계획하는 기초 자료를 수립하였다.

차량 정밀 측위용 이중대역 GPS 안테나 설계 (Design of a Vehicle-Mounted GPS Antenna for Accurate Positioning)

  • 느팜;정재영
    • 한국전자통신학회논문지
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    • 제11권2호
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    • pp.145-150
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    • 2016
  • 자율주행 차량 구현에 있어 차량의 위치에 대한 정확한 정보가 실시간으로 제공되어야 한다. 이동기준국 차분 측위 기술은 차량에 복수의 안테나에서 수신한 신호의 위상차를 통해 정밀 측위 정보를 생성하는 기술로, 이를 위해 차량의 평평하고 넓은 루프를 접지면으로 하는 이중대역 및 이중 원형편파 안테나 개발이 필수적이다. 본 논문에서 제안하는 안테나는 GPS L1과 L2 주파수 대역에서 공진을 일으키는 이중대역 안테나로써, 기존 안테나와 달리 급전부가 안테나 측면에 위치하여 복수의 안테나를 필요로 하는 시스템에 적합하다. 안테나 설계안은 중요 파라미터들의 이론값을 토대로 모델링한 초기 모델을 3D 전파시뮬레이션 소프트웨어를 이용해 최적화하는 방법으로 도출하였다. 최적화된 안테나의 시뮬레이션값과 측정값을 분석한 결과, L1과 L2에서 대역폭 6.1%와 3.7%, 축비 1% 이상임을 확인하였다. 안테나 크기는 $73mm{\times}73mm{\times}6.4mm$로 소형 구조의 장점을 갖췄다.

임해준설매립지 토양의 깊이별 이화학적 특성 (Physicochemical Properties of Depth-based Soil on the Reclaimed Dredging Area)

  • 남웅;곽영세;정인호;이덕범;이상석
    • 한국환경복원기술학회지
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    • 제11권5호
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    • pp.60-71
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    • 2008
  • Through analyzing the specific physicochemical alterations in depth-based soil at reclaimed dredging area, the baseline data were provided for developing the reclaimed dredging area as natural landscape planting sites and ecological-landscape sites based on the soil improvement technology. There was no physical disturbance for 15 to 20 years in Gwangyang Bay reclaimed dredging area after reclamation. Physicochemical examinations of the soil were performed based on the vertical depth. Results of physicochemical analysis such as pH, electric conductivity, total salt contents, silt, clay contents, available phosphorus, calcium, magnesium, sodium, chlorine, and sodium-adsorption ratio showed increasing patterns with the depth while total organic contents, total nitrogen, and sand showed decreasing patterns. Potassium as an exchangeable cation, showed similar distribution patterns between the shallow and deep soil. This result strongly implied that long-term exposure to natural rainfall in reclaimed dredging area altered soil characteristics related to salinity. This research demonstrated that there were no remarkable differences in physicochemical characteristics at soil depth and groundwater table height, suggesting a baseline data for developing reclaimed dredging area. Additional investigation is required for different reclaimed dredging areas. Also, additional monitoring and examination are need on plant communities and time variable alteration in the soil to test the feasibility of reclaimed dredging areas as natural landscape planting sites and ecological-landscape sites.

Improvement in periodontal healing after periodontal surgery supported by nutritional supplement drinks

  • Lee, Jaeri;Park, Jung-Chul;Jung, Ui-Won;Choi, Seong-Ho;Cho, Kyoo-Sung;Park, Yoo-Kyoung;Kim, Chang-Sung
    • Journal of Periodontal and Implant Science
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    • 제44권3호
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    • pp.109-117
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    • 2014
  • Purpose: The aim of this study was to determine the effects of nutritional supplements on periodontal health and tooth mobility after surgery. Methods: Patients were randomly assigned to an intervention group who consumed nutritional supplement drinks for 8 weeks, while the placebo group did not receive any such supplements. The gingival index (GI) and tooth mobility were measured at baseline and at 1, 4, and 8 weeks. In addition, the oral health impact profile-14 and anthropometric measurements along with loss of appetite and dietary intake were assessed at baseline and 8 weeks. Results: At 1 week, GI values were reduced in the intervention group (P<0.05), and tooth mobility had increased, but to a lesser extent in the intervention group (P<0.05). At 8 weeks, the intakes of protein, vitamins A and B1, and niacin were increased in the intervention group. Conclusions: These results demonstrate that nutritional supplementation improves early periodontal healing after surgery.

Comparing the effectiveness of ultrasound guided versus blind genicular nerve block on pain, muscle strength with isokinetic device, physical function and quality of life in chronic knee osteoarthritis: a prospective randomized controlled study

  • Cankurtaran, Damla;Karaahmet, Ozgur Zeliha;Yildiz, Sadik Yigit;Eksioglu, Emel;Dulgeroglu, Deniz;Unlu, Ece
    • The Korean Journal of Pain
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    • 제33권3호
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    • pp.258-266
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    • 2020
  • Background: The genicular nerve block (GNB) is demonstrated from several reports to alleviate pain and improve knee functionality in patients with chronic knee osteoarthritis (OA). Ultrasound (US)-guided GNB has been the most used imaging method. This study aimed to compare the effectiveness of US-guided versus blind GNB in the treatment of knee OA. Methods: This prospective, randomized clinical trial included patients with knee OA based on American College of Rheumatology diagnostic criteria. The patients were evaluated for clinical and dynamometer parameters at the baseline, 4 weeks after treatment, and 12 weeks after treatment. The patients underwent blind injection or US-guided injection. Results: When compared with the baseline, both groups showed significant improvement in pain, physical function, and quality of life parameters. Significant differences were observed between the groups for clinical parameters (30-second chair stand test, 6-minute walk test) in favor of the US-guided group. On the other hand, blind injection was more significantly effective on some parameters of the Nottingham Health Profile. There wasn't any significant improvement in isokinetic muscle strength for either group. Conclusions: This study demonstrated that both US-guided and blind GNB, in the treatment of knee OA, were effective in reducing symptoms and improving physical function. GNB wasn't an effective treatment for isokinetic muscle function. US-guided injections may yield more effective clinical results than blind injections.

심실간 공간 압력을 이용한 이동작동기형 완전이식 인공심장에서의 좌, 우심방압 추정 (Relationship between atrial pressures and the interventricular pressure in the moving actuator type total artificial heart)

  • 조영호;최원우;박성근;최재순;이종진;엄경식;김희찬;민병구
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1996년도 춘계학술대회
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    • pp.88-90
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    • 1996
  • The right and left atrial pressures are important parameters in automatic control of a total artificial heart (TAH) within normal physiological ranges. Our TAH is composed of a moving actuator, right and left ventricles and the interventricular space enclosed by a semi-rigid housing. During operation of the TAH, the jnterventpicular space's volume is changed dynamically by the difference between the ejection volume of one ventricle and the inflow volume of the other. Therefore, the changes in pressure of the interventricular space is related to both atrial pressures. We measured the interventricular pressure (IVP) waveform using a pressure sensor and attempted to indirectly estimate the changes of atrial pressures. This method has an advantage that the sensor does not contact the blood directly. Furthermore, the IVP waveforms have its zero baseline in each pump cycle, thus the pressure measurements are free from the transducer drift problems by measuring the peak pressure from these baseline values. From the In vitro experiments, we found that the IVP waveform contained several useful parameters such as negative peak, dP/dT on the initial break, the area enclosed by the profile in each stroke, which are associated with atrial pressures and the filling conditions of the ventricles. The measured atrial pressures were linearly related to the negative peak of the interventricular pressure.

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방기황기탕의 유전자 다형성에 따른 비만 치료 효과 : 무작위 배정, 이중 맹검, 위약-대조군 임상시험 (Impact of GNB3, ADRB3, UCP2, and PPAR${\gamma}$-Pro12Ala polymorphisms on Boiogito response in obese subjects : A randomized, double-blind, placebo-controlled trial)

  • 박정현;;임지연;김호준
    • 한방비만학회지
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    • 제12권2호
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    • pp.28-43
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    • 2012
  • Objectives: The aim of the study was to investigate the efficacy of Boiogito for obesity. We examined the efficacy of Boiogito for obese patients and we expected the reaction of Boiogito would vary according to the single nucleotide polymorphism(SNPs). Methods: 111 subjects(body mass index${\geq}25m/kg^2$) were recruited and randomized to receive Boiogito(n=55) or Placebo(n=56) for 8weeks. Anthropometric factors, serum lipid profile, glucose, blood pressure(BP), pulse rate, resting metabolic rate and Korean version of obesity-related quality of life(KOQOL) scale measured at baseline and 8weeks. SNPs(${\beta}3$-adrenergic receptor(ADRB3), G protein ${\beta}3$(GNB3), peroxisome proliferator activated receptor gamma 2 gene(PPAR-${\gamma}2$), uncoupling protein(UCP2)) were conducted at baseline. Adverse reactions and safety outcome variables were also checked during trials. Results: Both groups showed significant improvement on obesity after treatment. Boiogito group decreased triglyceride than did control group and improved KOQOL. Boiogito showed a significant higher efficacy in C/T and T/T genotype of GNB3 gene / in Trp64 and Arg64 genotype of ADRB3 gene / in D/D genotype of UCP2 gene / in Pro/Pro genotype of PPAR-${\gamma}$ gene. Conclusions: Boiogito promoted obesity indexes without severe adverse reactions and proved its safety. Pharmacogenetical studies of Boiogito on obesity could be a effective method for the individualized treatment and prevention of obesity.

청지각 훈련과 병행한 감각통합치료가 발달지연 아동의 감각처리, 시 지각 발달, 주의집중에 미치는 영향: 개별실험연구 (The Effects of Sensory Integration Intervention Combined With Auditory Perception Training on Sensory Processing, Visual Perception and Attention of Children With Developmental Delay: Single-Subject Design)

  • 박미영;임영명;김희
    • 대한감각통합치료학회지
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    • 제15권2호
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    • pp.66-79
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    • 2017
  • 목적 : 본 연구는 발달지연 아동에게 청지각 훈련과 병행한 감각통합 치료를 시행하여 감각처리, 시지각 발달, 주의집중에 미치는 영향을 알아보고자 한다. 연구방법 : 발달지연 및 의심소견을 보이는 아동 만 4~7세 아동 3명을 대상으로 2016년 11월부터 2017년 1월 까지 총 9주간 청지각 훈련과 감각통합치료를 병행하여 실시하고 평가 하였다. 개별실험연구방법(single subject research design)중 ABA' 설계를 사용하였으며, 기초선 1기간(A) 4회, 치료 1기간(B)15회, 기초선2 기간(A')4회로 총 23회기를 적용하였다. 시지각 능력은 기초선 A와 A'기간에 Korean Developmental Test Visual Perception-2(K-DTVP-2)를 통하여 측정하였고 감각처리능력은 감각프로파일(Sensory Profile)로 평가하였다. 주의집중 행동의 유지시간은 기초선 기간에 중재가 없는 상태에서 측정하였으며 중재 기간에는 매 중재 후 10분간 마무리 활동시 소근육 과제를 제공하여 비디오로 촬영하였고 등간기록법(interval recording)의 전간기록법을 사용하여 30초 간격으로 주의집중 발생을 평가하였다. 결과 : 청지각 훈련과 감각통합치료를 실시하기 전보다 후에 시지각 기능과 감각처리의 점수의 수치상 향상은 있었고, 주의집중에서는 A아동에게서 통계적으로 유의한 차이가 있었으나 B, C 아동은 통계적으로 유의한 차이가 없었다. 결론 : 청지각 훈련을 병행한 감각통합 치료가 발달지연 아동의 시지각 기능과 주의집중에 긍정적인 영향을 미친다고 결론짓기에는 한계가 있다. 그러나 일부 발달지연 아동에게서 주의집중의 유의미한 증진이 있었고 점수의 향상이 있었다. 향후 발달지연 아동에게 연구기간, 표준데이터를 제시할 수 있는 평가도구를 적용한다면 명확한 결과가 나타날 수 있을 것이다. 또한 주의집중 유도와 학습을 준비하기 위한 치료방법으로 청지각 훈련의 연구가 추가적으로 시행되어야 한다.

Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria

  • Danjuma, Sale;Dauda, Happy Amos;Kene, Aghadi Ifeanyi;Akau, Kache Stephen;Jinjiri, Ismail Nasiru
    • Journal of Korean Neurosurgical Society
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    • 제65권5호
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    • pp.751-757
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    • 2022
  • Objective : Tumours of the brain are a rare occurrence accounting for approximately 2% of all neoplasms in adults. Few studies have been done in Nigeria on the profile of brain tumours. The aim of this study is to determine the profile of brain tumours in general and determine the change in Kanofsky Performance Score (KPS) after treatment. Methods : This is a prospective hospital-based study in Kaduna. All consecutive patients over 18 years of age with diagnosis of brain tumours from January 2016 to December 2019 were included in the study. Demographic and clinical data was collected using a proforma during the study. Patients who received treatment were followed up for 12 months. The primary outcome data was the difference in the quality of life as measured by KPS at the point of first contact and at 1-month after treatment and at 12-month follow up. Data obtained was analysed with SPSS version 25.0 for Windows. Descriptive statistics was done to determine the profile. Paired t-test at 95% confidence interval was done to check for significant correlation between the mean KPS. Results : A total of 39 consecutive patients were included in the study. There was a slight male preponderance with a M : F of 1.17 : 1. Meningioma and metastasis were more common in females while gliomas and pituitary tumours were more common in males. The mean age of patients was 49.8 years and standard deviation of 11.8 years. Pituitary tumours were the most common tumours. The most common location of the tumour was frontal lobe followed by the pituitary gland. The mean duration of symptoms before neurosurgical consultation was 38 weeks. The most common presenting symptoms of patient with brain tumour was headache. The quality of life improve compare to the baseline in 81% of patient at discharge and at 1 year follow up. The overall mortality rate was 25.6%. Conclusion : The most common brain tumour in our study is pituitary tumour. Most patients present late. The most common presenting symptoms is headache. There is significant improvement in the KPS of patients following treatment. The overall mortality rate at 1-year post treatment is 25.6%.