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Low-level Laser Therapy with Novel Array of Light Source and Individualized Program for Treatment of Androgenetic Alopecia: A 16-week, Randomized, Double-blind, Sham Device-controlled Study

  • Kim, Jee-Woo;Kwon, Yeo-Seon;Chang, Yoon-Young;Hong, Sung-Ho;Shin, Jung-Won;Na, Jung-Im;Huh, Chang-Hun
    • Medical Lasers
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    • v.9 no.2
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    • pp.150-158
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    • 2020
  • Background and Objectives Low-level laser therapy (LLLT) is used widely to promote hair growth in androgenetic alopecia (AGA). This study examined the clinical efficacy and safety of a home-use LLLT device with a newly designed array of light sources and software optimized for individual types of AGA. Materials and Methods The study was a randomized, double-blind, sham device-controlled trial. Forty-eight subjects (39 men and nine women) were assigned randomly in a 2:1 ratio to use either the test device (LG Pra'L HGN1, LG electronics, Korea) or sham device. The subjects used the LLLT device three times a week for 16 weeks. Phototrichogram was used to measure the hair density and hair thickness at 0, 8, and 16-weeks. Adverse events were closely monitored. Results After 16 weeks of using the device, the test group showed a significant increase in hair density and hair thickness compared to the control. In the test group, the hair density increased 6.96 counts/cm2 at eight weeks and 13.67 counts/cm2 at 16 weeks from the baseline. The hair thickness increased 7.21 ㎛ at eight weeks and 11.80 ㎛ at 16 weeks compared to the baseline. Conclusion The home-use LLLT device with a novel array of light sources and an individualized program according to the types of hair loss appears to be an effective and safe treatment modality for both male and female AGA patients.

Child health promotion program in South Korea in collaboration with US National Aeronautics and Space Administration: Improvement in dietary and nutrition knowledge of young children

  • Lim, Hyunjung;Kim, JiEun;Wang, Youfa;Min, Jungwon;Carvajal, Nubia A.;Lloyd, Charles W.
    • Nutrition Research and Practice
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    • v.10 no.5
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    • pp.555-562
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    • 2016
  • BACKGROUND/OBJECTIVES: Childhood obesity has become a global epidemic. Development of effective and sustainable programs to promote healthy behaviors from a young age is important. This study developed and tested an intervention program designed to promote healthy eating and physical activity among young children in South Korea by adaptation of the US National Aeronautics and Space Administration (NASA) Mission X (MX) Program. SUBJECTS/METHODS: The intervention program consisted of 4 weeks of fitness and 2 weeks of nutrition education. A sample of 104 subjects completed pre- and post- surveys on the Children's Nutrition Acknowledgement Test (NAT). Parents were asked for their children's characteristics and two 24-hour dietary records, the Nutrition Quotient (NQ) at baseline and a 6-week follow-up. Child weight status was assessed using Korean body mass index (BMI) percentiles. RESULTS: At baseline, 16.4% (boy: 15.4%; girl: 19.2%) of subjects were overweight or obese (based on $BMI{\geq}85%tile$). Fat consumption significantly decreased in normal BMI children ($48.6{\pm}16.8g$ at baseline to $41.9{\pm}18.1g$ after intervention, P < 0.05); total NQ score significantly increased from 66.4 to 67.9 (P < 0.05); total NAT score significantly improved in normal BMI children (74.3 at baseline to 81.9 after the program), children being underweight (from 71.0 to 77.0), and overweight children (77.1 at baseline vs. 88.2 after intervention, P < 0.001). CONCLUSIONS: The 6-week South Korean NASA MX project is feasible and shows favorable changes in eating behaviors and nutritional knowledge among young children.

The Effect of Optokinetic Stimulation with Smooth Pursuit Eye Movement to Chronic Hemispatial Neglect: A Pilot Study (완곡 추적 안구운동을 동반한 시운동자극이 만성 편측무시에 미치는 영향 : 예비연구)

  • Shin, Jae-Yong;Yoo, Eun-Young
    • Therapeutic Science for Rehabilitation
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    • v.5 no.2
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    • pp.81-92
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    • 2016
  • Objective: This study aim is to identify whether 30minutes optokinetic stimulation(OKS) with smooth pursuit eye movement can alleviate chronic hemispatial neglect. Methods: We applied optokinetic stimulation with smooth pursuit eye movement to 2 chronic hemispatial neglect patients. experimental duration was total 4weeks - 1week baseline, 2weeks OKS intervention, 1week 2nd. baseline. The intervention was 10 OKS sessions (30min each, 1session daily, from Monday to Friday) over a period of 2weeks. The neglect test carried out 3 times a week every other day. The OKS was provided on the screen when patient sat in front of the screen(13.5 inch). The OKS video that the 24 yellow squares moving coherently from the right to the left side. Patients were instructed to perform smooth pursuit eye movement without head and neck movement. Results: As a result of the OKS for 2weeks, the degree of neglect trends to decrease on both 2 cases compared to baseline A. The degree of the neglect of subject 1 tended to increase the at the baseline A. In contrast, the subject 2 showed that tendency that the degree of the neglect declined additionally at the baseline A. Conclusions: We identified that 30 minutes optokinetic stimulation with sooth pursuit eye movement is effective intervention method for chronic hemispatial neglect.

The Effect of Smooth Pursuit Eye Movement Using Portable Device to Chronic Hemispatial Neglect: A Pilot Study (휴대용 디바이스를 이용한 완곡추적 안구운동이 만성 편측무시에 미치는 영향: 예비연구)

  • Shin, Jae-Yong
    • Therapeutic Science for Rehabilitation
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    • v.6 no.1
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    • pp.71-83
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    • 2017
  • Objective : This study aim is to identify whether smooth pursuit eye movement(SPEM) using portable device can alleviate chronic hemispatial neglect. Methods : We applied smooth pursuit eye movement to one chronic hemispatial neglect patient. Experimental duration was total 4weeks - 1week baseline, 2weeks SPEM intervention, 1week 2nd. baseline. The intervention was 10 SPEM sessions (30min each, 1session daily, from Monday to Friday) over a period of 2weeks. The neglect test carried out 5 times a week. The SPEM was provided on the screen when patient sat in front of the screen(8.4 inch tablet pc, distance 40cm). The SPEM video that the 24 yellow squares moving coherently from the right to the left side. Patients were instructed to perform smooth pursuit eye movement without head and neck movement. Results : As a result of the SPEM for 2weeks, the degree of neglect tended to decrease compared to baseline A. The degree of the LBT tended to increase the at the baseline A'. In contrast, the SCT showed that tendency which the degree of the neglect maintained at the baseline A'. Conclusion : We identified that SPEM using portable device is effective intervention method for chronic hemispatial neglect.

Role of the Baseline Heart Rate Variability to the Effect of the Huanglian-Jie-Du Granule in Hwa-Byung Patients: Supplementary Analysis from the Randomized Trial Comparing Huanglian-Jie-Du Granule and Placebo for Hwa-Byung (화병 환자의 심박변이도 차이에 따른 황련해독탕의 효과: 화병에 대한 무작위 대조 비교임상시험 결과의 추가 분석)

  • Choi, Yu-Jin;Cho, Seung-Hun
    • Stress
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    • v.26 no.4
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    • pp.305-311
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    • 2018
  • Background: The purpose of the study was to explore whether the effect of Huanglian-jie-du granule depends on the baseline heart rate variability in patients with Hwa-byung. Methods: We used the supplementary data from a randomized, double-blind, placebo-controlled trial of Huanglian-jie-du granule for Hwa-byung patients. Study drugs were taken orally three times per day for one week. Heart rate variability was measured three times; before the treatment, after the treatment, and month follow-up period. Spearman's rho test was done to explore the role of the baseline heart rate variability to the effect of Huanglian-jie-du granule. Results: Baseline low frequency power of heart rate variability was negatively correlated with the reduction of the insomnia severity index in experimental group (r=-0.493 p=0.02). Also, Huanglian-jie-de granule significantly decreased the low frequency power of heart rate variability in patients with Hwa-byung compared to placebo (mean difference 266 [95% CI: 29~503], p=0.028). In Hwa-byung symptoms, stuffy, pushing up in the chest, and flush of anger were correlated with low frequency power of heart rate variability (p=0.010, p=0.000, and p=0.016, respectively). Conclusions: The effect of the Huanglian-jie-de granule for insomnia seems to be lower when the baseline low frequency power of heart rate variability is higher in Hwa-byung patients. Also, Huanglian-jie-de granule is likely to decrease the sympathetic activity in patients with Hwa-byung. Measurement of heart rate variability may be the useful to understand the state of Hwa-byung patients.

Role of Methacholine PC20 in FEF25-75% for the Diagnosis of Bronchial Asthma

  • Son, Kyeong Min;Jang, Seung Hun;Kang, Hye Ryun;Han, Bo Ram;Kim, Joo Hee;Kim, Hyun Sung;Park, Sung Hoon;Hwang, Yong Il;Kim, Dong Gyu;Jung, Ki Suck
    • Tuberculosis and Respiratory Diseases
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    • v.67 no.4
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    • pp.311-317
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    • 2009
  • Background: The methacholine bronchial provocation test is a useful tool for evaluating asthma in patients with normal or near normal baseline lung function. However, the sensitivity of this test is 82~92% at most. The purpose of this study is to evaluate the clinical usefulness of $FEF_{25-75%}$ in identification of airway hyperresponsiveness in patients with suspected asthmatic symptoms. Methods: One hundred twenty-five patients who experienced cough and wheezing within one week prior to their visiting the clinic were enrolled. Results: Sixty-four subjects showed no significant reduction of $FEV_{1}$ or $FEF_{25-75%}$ on the methacholine bronchial provocation test (Group I). In 24 patients, $FEF_{25-75%}$ fell more than 20% from baseline without a 20% fall of $FEV_{1}$ during methacholine challenge (Group II). All patients who had more than 20% fall of $FEV_{1}$ (n=37) also showed more than 20% of reduction in $FEF_{25-75%}$ (Group III). Baseline $FEV_{1}$/FVC (%) and $FEF_{25-75%}$ (L) were higher in group II than group III (81.51${\pm}$1.56% vs. 75.02${\pm}$1.60%, p<0.001, 3.25${\pm}$0.21 L vs. 2.45${\pm}$0.21 L, p=0.013, respectively). Group II had greater reductions of both $FEV_{1}$ and $FEF_{25-75%}$ than group I at 25 mg/mL of methacholine (p<0.001). The provocative concentration of methacholine causing a 20% fall in $FEF_{25-75%}$ in group II was about three-fold higher than that in group III. Conclusion: A 20% fall of $FEF_{25-75%}$ by methacholine provocation can be more sensitive indicator for detecting a milder form of airway hyperresponsiveness than $FEV_{1}$ criteria.

Survey study of powered toothbrush with guiding device for oral hygiene improvement (유도장치가 부가된 진동회전방식 전동칫솔의 구강건강증진효과에 대한 조사연구)

  • Park, Yun-Soo;Lee, Chul-Woo;Hahm, Byoung-Do;Koo, Ki-Tae;Kim, Tae-Il;Seol, Yang-Jo;Lee, Yong-Moo;Rhyu, In-Chul;Gu, Young;Chung, Chong-Pyoung
    • Journal of Periodontal and Implant Science
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    • v.39 no.4
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    • pp.407-412
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    • 2009
  • Purpose: This study was performed to evaluate the effect of powered toothbrush with a wireless remote display on the subjective and objective oral hygiene improvement. Methods: One hundred and fifteen subjects in healthy or mild gingivitis status between the ages of 20 and 90 were recruited and reviewed for study inclusion criteria. At first visit, 115 pre-screened subjects filled in the questionnaire form which consisted of demographic factors, behavioral factors (smoking, alcohol consumption), toothbrushing habits (brushing time and frequency), self-reported oral health status, and self-satisfaction. Baseline clinical indices (Plaque index, Gingival index) were also recorded by a periodontist. Subjects were instructed how to use powered toothbrush with a wireless remote display, and were provided with it. Thirty days after first visit, 90 subjects returned for the second assessment by self-reported questionnaire form and professional clinical checkup. Statistical analysis was performed using paired t-test for the difference between baseline and second visit data. The relationship among variables was examined with chi-square test and Fisher' s exact test. Results: Significant differences were not found on self-reported satisfaction related with sex, smoking, alcohol consumption (P<0.05). Self-reported tooth brushing habit was improved in the aspect of brushing time and frequency. Significant differences were found on the self-reported oral health status, self-satisfaction, and clinical indices between the baseline and second visit data (P<0.01). Clinical indices were significantly reduced after using powered toothbrush with a wireless remote display (P<0.01). No adverse reactions were reported during the study period. Conclusions: Powered toothbrush with a wireless remote display successfully promoted oral hygiene from the subjective and objective viewpoint after 30 days of home usage.

EVALUATION OF ROAD-INDUCED NOISE OF A VEHICLE USING EXPERIMENTAL APPROACH

  • Ko, K.-H.;Heo, J.-J.;Kook, H.
    • International Journal of Automotive Technology
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    • v.4 no.1
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    • pp.21-30
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    • 2003
  • In this paper a systematic test procedure for evaluation of road-induced noise of a vehicle and guidelines for each test are presented. Also, a practical application of the test procedure to a small SUV is presented. According to the test procedure, all the tests were performed to evaluate road-induced booming noise that is in low frequency range. First of all the information on characteristics of road-induced noise was obtained through baseline test. Coupling effects between body structure and acoustic cavity of a compartment were obtained by means of modal tests for a structure and an acoustic cavity. Local stiffness of joint areas between chassis system and car-body was determined by test for measurement of input point inertance. Noise sensitivities of body joints to operational forces were obtained through test for measurement of noise transfer functions. Operational deflection shapes made us analyze behaviors of chassis system under running condition and then find sources of noise due to resonance of the chassis system. Finally, Principal Component Analysis and Transfer Path Analysis were utilized to investigate main paths of road-induced noise. In order to evaluate road-induced booming noise exactly, all of tests mentioned above should be performed systematically.

Effect of Visual Scanning Program on the Visual Memory of Stroke Patients: Single Subject Research Design (시각탐색(visual scanning) 프로그램이 뇌졸중 환자의 시각기억에 미치는 영향: 단일 사례연구)

  • Hwang, Sun-Jung;Kim, Jung-Mi
    • The Journal of Korean society of community based occupational therapy
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    • v.3 no.1
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    • pp.67-75
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    • 2013
  • Objective : The purpose of study was to visual scanning program on the effect of visual memory in stroke patients. Method : A single subject experimental research with ABA design was employed in this study. The experiment composed of 15 sessions in total: 5 sessions for baseline, 7 session for visual scanning program, and 3 sessions for the second baseline. Each session for intervention took 30 minutes daily. MVPT, CNT(visual span test, visual learning test) were used for assessment visual perception, visual memory. Result : After visual scanning program, changing faster processing time MVPT 5.5 seconds to 4.5 seconds. Also all itme raw score changes of CNT visual span test, visual learning test. Conclusion : Visual scanning program in stroke patients give a positive impact on the visual memory. To improve stroke patients' perception visual scanning program utilizing visual perception research as well as training programs for a variety of looks forward to being developed.

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Nondestructive Evaluation of Railway Bridge by System Identification Using Field Vibration Measurement

  • Ho, Duc-Duy;Hong, Dong-Soo;Kim, Jeong-Tae
    • Journal of the Korean Society for Nondestructive Testing
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    • v.30 no.6
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    • pp.527-538
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    • 2010
  • This paper presents a nondestructive evaluation approach for system identification (SID) of real railway bridges using field vibration test results. First, a multi-phase SID scheme designed on the basis of eigenvalue sensitivity concept is presented. Next, the proposed multi-phase approach is evaluated from field vibration tests on a real railway bridge (Wondongcheon bridge) located in Yangsan, Korea. On the steel girder bridge, a few natural frequencies and mode shapes are experimentally measured under the ambient vibration condition. The corresponding modal parameters are numerically calculated from a three-dimensional finite element (FE) model established for the target bridge. Eigenvalue sensitivities are analyzed for potential model-updating parameters of the FE model. Then, structural subsystems are identified phase-by-phase using the proposed model-updating procedure. Based on model-updating results, a baseline model and a nondestructive evaluation of test bridge are identified.