• Title/Summary/Keyword: Base position

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O-Alkylation Using Ag2O; Synthesis of Novel 4-Alkyloxy-2-phenylcarboxamidyl-1-tosylpyrrolidines (산화은을 이용한 O-알킬화 반응; 새로운 4-알킬옥시-2-페닐카복사미딜-1-토실피롤리딘 유?체의 합성)

  • Park, Myeong Suk
    • Journal of the Korean Chemical Society
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    • v.45 no.6
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    • pp.549-554
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    • 2001
  • For the development of new COX-2 inhibitor, novel compound were synthesized through induction an arylsulfonyl group to 1-position, an arylcarboxamidyl group to 2-position and an alkyl group to 4-position of L-proline. We started from 4-hydroxy-L-proline, the 4-methylphenylsulfonyl of 1-position was introduced through N-tosylation and the carboxylic acid group was protected by esterification. We sucessfully converted to a various derivatives 4b-d for O-alkyl-(or aralkyl)ation of 4-position using silver oxide as catalysis. The 4-alkyloxy-1-tosyl L-prolines 5b-d were synthesized through base-hydrolysis for the deprotection of carboxylic acid. Final compound 1,2,4-substituted pyrrolidines, 4-alkyloxy-2-phenylcarboxamidyl-1-tosyl pyrrolidines 6a-d were synthesized through the condensation of arylamine with 3 and 5b-d using DCC.

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Position Fixing Accuracy of TDOA Direction Finding Method (TDOA 방위탐지방식의 위치표정 정확도)

  • Lim, Joong-Soo;Chae, Gyoo-Soo
    • Journal of Digital Convergence
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    • v.12 no.11
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    • pp.373-378
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    • 2014
  • The technology of direction finding is very important to make high position fixing accuracy. TDOA(time difference of arrival) direction finding technology is a high accuracy technology and is used in RF system from 1990. The principle of TDOA is to receive an emitter signal with two antennas, measure the time difference of received signal and then convert the time differences to azimuth angle. For high DF(direction finding) accuracy long basis line and high SNR at receiving system are needed. The DF accuracy and position fixing accuracy are simulated with different SNRs and antenna base lines. We obtain the DF accuracy of $0.51^{\circ}$ at $0^{\circ}$ incident azimuth angle in case of 50m base line and 40dB SNR.

Functional Analysis of the Invariant Residue G791 of Escherichia coli 16S rRNA

  • Song, Woo-Seok;Kim, Hong-Man;Kim, Jae-Hong;Sim, Se-Hoon;Ryou, Sang-Mi;Kim, Sang-Goo;Cha, Chang-Jun;Cunningham, Philip R.;Bae, Jee-Hyeon;Lee, Kang-Seok
    • Journal of Microbiology
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    • v.45 no.5
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    • pp.418-421
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    • 2007
  • The nucleotide at position 791(G791) of E. coli 16S rRNA was previously identified as an invariant residue for ribosomal function. In order to characterize the functional role of G791, base substitutions were introduced at this position, and mutant ribosomes were analyzed with regard to their protein synthesis ability, via the use of a specialized ribosome system. These ribosomal RNA mutations attenuated the ability of ribosomes to conduct protein synthesis by more than 65%. A transition mutation (G to A) exerted a moderate effect on ribosomal function, whereas a transversion mutation (G to C or U) resulted in a loss of protein synthesis ability of more than 90%. The sucrose gradient profiles of ribosomes and primer extension analysis showed that the loss of protein-synthesis ability of mutant ribosomes harboring a base substitution from G to U at position 791 stems partially from its inability to form 70S ribosomes. These findings show the involvement of the nucleotide at position 791 in the association of ribosomal subunits and protein synthesis steps after 70S formation, as well as the possibility of using 16S rRNA mutated at position 791 for the selection of second-site revertants in order to identify ligands that interact with G791 in protein synthesis.

Measurement of Micro Thermal Deformation of Optical Pick-up Base Using Holographic Interferometry (흘로그램 간섭계를 이용한 광픽업 베이스의 미소 열변형 측정)

  • 서영민;강신일
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2002.05a
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    • pp.191-194
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    • 2002
  • In optical pick-up, optical components such as objective lens, collimator, mirror, laser diode and photo diode are mounted on the pick-up base. These components must keep their original position during operation for proper transmittance of information from laser diode to optical disk and back to photo diode. However, micro thermal deformation of pick-up base which is induced by thermal environment during operation can deteriorate the performance of optical pick-up. Therefore, it is important to measure and analyze the thermal deformation behavior of pick-up base under thermal environment. In the present study, a measurement system using holographic interferometry was designed to measure micro thermal deformation of pick up base. The measurement system was verified by using the deformation of cantilever with prescribed motion actuated by PZT with 1 nm resolution. Interferometric measurement was compared quantitatively with that induced by PZT actuator. Finally, micro thermal deformation of pick-up base under actual thermal environment was measured using the present holographic interferometry and the results were analysed.

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The Study of Characteristics of Korea Fog and Forecast Guidance (한반도 안개 특성 분석 및 예보 기법 연구)

  • Kim, Jun-Sik;Kim, Jae-Hwan;Park, Sang-Hwan;Kim, Young-Chul
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.21 no.1
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    • pp.68-73
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    • 2013
  • This study is to make a protype of forecast guidance for forecasters from analyzing the characteristics of Korea Fog. The trend of Korea fog showed the decline in the number of foggy days and the duration time, the gradient is -1.24days/year under 3 miles and -0.98days/year under 1 mile and -1.64hours/year under 3 miles and -3.18hours/year under 1 mile in duration time in 27 ROKAF base. To find the protype of inland and coastal forecast guidance, Daegu base as a representation of the inland base and Gangneung base as the representation of the coastal base were chosen. For Daegu base, the mixture of relative humidity, sky condition, and the position of high pressure were selected for the forecast guidance. For Gangneung base, pressure pattern, sea surface temperature, sea currents, and 850hPa temperature patterns were selected for the forecast guidance.

Channel Condition Adaptive Error Concealment using Scalability Coding (채널상태에 적응적인 계층 부호화를 이용한 오류 은닉 방법 연구)

  • Han Seung-Gyun;Park Seung-Ho;Suh Doug-Young
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.1B
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    • pp.8-17
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    • 2004
  • In this paper: we propose the adaptive error concealment technique for scalable video coding over wireless network error prove environment. We prove it is very effective that Error concealment techniques proposed in this paper are applied to scalable video data. In this paper, we propose two methods of error concealment. First one is that the en·or is concealed using the motion vector of base layer and previous VOP data. Second one is that according to existence of motion vector in error position, the error is concealed using the same position data of base layer when the motion vector is existing otherwise using the same position data of previous VOP when the motion vector is 0(zero) adaptively. We show that according to various error pattern caused by condition of wireless network and characteristics of sequence, we refer decoder to base layer data or previous enhancement layer data to effective error concealment. Using scalable coding of MPEG-4 In this paper, this error concealment techniques are available to be used every codec based on DCT.

Management of Dripper Position in Tomato Perlite Bag Culture (토마토 펄라이트 자루재배에서의 점적핀 위치 관리)

  • Sim, Sang-Youn;Kim, Young-Shik
    • Journal of Bio-Environment Control
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    • v.18 no.4
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    • pp.413-419
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    • 2009
  • The appropriate dripper position in perlite bag was investigated for tomato production. Drippers were laid at 5(F5), 15cm (F15) away from the stem base or 5cm at first and then moved to 15cm later (M5-15). Roots were developed more near the stem base in F5, while less in F15. Roots were distributed evenly in M5-15. In vertical distribution of water in perlite bag, water content was higher as it went deeper with the variation by dripper positions. Yield was high in F15 and low in F5. In conclusion the position of dripper is the best at 15cm from the stem base in perlite bag culture in view of root distribution and yield.

A STUDY ON THE ANTERO-POSTERIOR MORPHOLOGY OF THE UPPER FACE IN ANGLE'S CLASS III MALOCCLUSION PATIENTS (Angle씨 III급 不正交合者(부정교합자) 上顔面(상안면)의 前後方(전후방) 形態(형태)에 관한 硏究(연구))

  • Lee, Jee-Hee;Cha, Kyung-Suk
    • The korean journal of orthodontics
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    • v.24 no.2
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    • pp.395-403
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    • 1994
  • To find out the antero-posterior morphology of the upper face in Angle's class III malocclusion patients, 90 patients, adults in Heilman's Dental age, were used as samples and following results were obtained after the relative comparision of antero-posterior relationship of upper facial structures between Angle's class I malocclusion patients and Angle's class III malocclusion patients and of antero-posterior size of upper facial structures to horizontal and vertical structures in each patients. 1. After comparison of the distance from PMV line to anterior margin of maxillary sinus and cheek, which determines the antero-posterior position of the upper face, upper face in Angle's class III patients are underdeveloped relative to Angle's class I patients. The distance between orbitale and anterior margin of maxillary sinus were greater in Angle's class I patients, whic implies thart the upper face in Angle's class III are depressed. 2. Antero-posterior dimension of anterior cranial base from PMV line and vertical dimension of upper face are statistically insignificant between two groups. After comparing antero-posterior position of upper face to anterior cranial base, the upper face in Angle's class Et patients are depressed antero-posteriorly in relation to anterior cranial base. Following the comparision of antero-posterior position of upper face in relation to vertical dimension of upper face, the upper face in Angle's class III patients seem to be narrow antero-posteriorly

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Drag reduction of a circular cylinder at subcritical flow regime using base shield plates

  • El-Khairy, Nabil A.H.
    • Wind and Structures
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    • v.6 no.5
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    • pp.347-356
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    • 2003
  • Experimental studies on drag reduction of a circular cylinder of diameter D were conducted in the subcritical flow regime at Reynolds numbers in the range $4{\times}10^4{\leq}Re{\leq}10^5$. To shield the cylinder rear surface from the pressure deficit of the unsteady vortex generation in the near wake, two shield plates were attached downstream of the separation points to form a cavity at the base region. The chord of the shield plates, L, ranged from 0.22 to 1.52 D and the cavity width, G, was in the range from 0 to 0.96 D. It is concluded that significant drag reductions from that of a plain cylinder may be achieved by proper sizing of the shield plates and the base cavity. The study shows that using a pair of shield plates at G/D of 0.86 and angular position ${\theta}$ of ${\pm}121^{\circ}$ results in a configuration with percentage drag reduction of 40% for L/D of 0.5, and 55% for L/D of 1.0.

Synthesis of Dimethyl Glutarate from Cyclobutanone and Dimethyl Carbonate over Solid Base Catalysts

  • Zhi, Chen;Dudu, Wu
    • Bulletin of the Korean Chemical Society
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    • v.33 no.6
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    • pp.1834-1838
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    • 2012
  • A facile route for the synthesis of dimethyl glutarate (DMG) from cyclobutanone and dimethyl carbonate (DMC) in the presence of solid base catalysts has been developed. It was found that the intermediate carbomethoxycyclobutanone (CMCB) was produced from cyclobutanone with DMC in the first step, and then CMCB was further converted to DMG by reacting with a methoxide group. The role of the basic catalysts can be mainly ascribed to the activation of cyclobutanone $via$ the abstraction of a proton in the ${\alpha}$-position by base sites, and solid bases with moderate strength, such as MgO, favor the formation of DMG.