• 한국자동차공학회논문집
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• 제11권6호
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• pp.101-107
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• 2003

Since stainless steel sheets have good mechanical properties, weldability, appearance and corrosion resistance, they are commonly used as one of the structural materials of the railroad cars or the commercial vehicles which are manufactured by the spat welding. Among the many kinds of spot welded lap joints, it can be found that multi-lap joints are employed in their body structure. But, fatigue strength of these joints is lower than that of base metal due to high stress concentration at the nugget edge of spot weld and is considerably influenced by welding conditions as well as the mechanical and geometrical factors. Thus, it is necessary to establish a reasonable and systematic design criterion for the long life design of the spot-welded body structures. In this paper, the stress distribution and deformation around the spot-welded multi-lap joints subjected to tensile shear load was numerically analyzed. Also, the $\Delta$P-Nf curve was obtained by fatigue tests. Using these results, $\Delta$P-Nf curves were rearranged in to the ${\Delta}{\sigma}$-Nf relation with the maximum stress at nugget edge of spot weld.

• Toxicological Research
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• 제29권3호
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• pp.211-215
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• 2013

The trace toxic metal copper was assayed using mercury immobilized on a carbon nanotube electrode (MCW), with a graphite counter and a reference electrode. In this study, a macro-scale convection motor was interfaced with a MCW three-electrode system, in which a handmade MCW was optimized using cyclic- and square-wave stripping voltammetry. An analytical electrolyte for tap water was used instead of an expensive acid or base ionic solution. Under these conditions, optimum parameters were 0.09 V amplitude, 40 Hz frequency, 0.01 V incremental potential, and a 60-s accumulation time. A diagnostic working curve was obtained from 50.0 to 350 ${\mu}g/L$. At a constant Cu(II) concentration of 10.0 ${\mu}g/L$, the statistical relative standard deviation was 1.78% (RSD, n = 15), the analytical accumulation time was only 60 s, and the analytical detection limit approached 4.6 ${\mu}g/L$ (signal/noise = 3). The results were applied to non-treated drinking water. The content of the analyzed copper using 9.0 and 4.0 ${\mu}g/L$ standards were 8.68 ${\mu}g/L$ and 3.96 ${\mu}g/L$; statistical values $R^2$ = 0.9987 and $R^2$ = 0.9534, respectively. This method is applicable to biological diagnostics or food surveys.

• Biomolecules & Therapeutics
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• 제13권2호
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• pp.90-94
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• 2005

Prazosin hydrochloride is an antihypertensive drug with selective ${\alpha}_1$-adrenoreceptor blocking effects. A simple high performance liquid chromatographic method has been developed and validated for the quantitative determination of prazosin in human plasma. A reversed-phase C18 column was used for the separation of prazosin and terazosin (internal standard) with a mobile phase composed of water, acetonitrile and triethylamine(75:25:0.1, V/V;pH5.0) at a flow rate of 1.5 ml/min. the fluorescence detector was set at excitation and emissionwavelengths of 250 and 370 nm, respectively. Intra-and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification of 0.5 ng/ml. Good recovery (>80%) was seen in plasma. Prazosin was stable in human plasma under various storage conditions. This method was used successfully for a pharmacokinetic study in plasma after oral administration of a single 2-mg dose as prazosin base to 16 healthy volunteers. The maximum plasma concentration of prazosin was 23.1 ${\pm}$ 16.5 ng/ml at 2.1 h, and the mean area under the curve and elimination half-life were calculated to be 108.4 ${\pm}$ 74.2 ng ${\cdot}$hr/ml and 2.5 ${\pm}$ 0.6 h, respectively.

• 한국정밀공학회지
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• 제23권1호
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• pp.113-120
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• 2006

This paper proposed the control algorithm fur aspheric surface grinding and was verified by the experiment. The functions of the algorithm were simultaneous control of the position and interpolation of the aspheric curve. The non-linear formula of the tool position was derived from the aspheric equations and the shape of the tool. The function was partitioned by an certain interval and the control parameters were calculated at each control section. The movement in a session was interpolated with acceleration and velocity. The position error was feed-backed by rotary encorder. The concept of feedback algorithm was correcting position error by increasing or decreasing the speed. In the experiment, two-axis machine was controlled to track the aspheric surface by the proposed algorithm. The effect of the control and process parameters was monitored. The result showed that the maximum tracking error was under sub-micro level for the concave and convex surfaces.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 추계 학술발표회
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• pp.3-25
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• 2010

The paper deals with two bearing capacity problems of shallow footing under combined loading. The first is a FEM study of shallow strip footing on two-layer clay deposits subjected to a vertical, horizontal and moment combined loading, while the second is a centrifuge study of shallow rectangular footing on dry sand under double eccentricity. The FEM results revealed that the existence of top soft layer sensitively affects more on horizontal and moment capacity than vertical capacity for cases of footing on soft clay overlying stiff clay. Practical design charts are presented to evaluate bearing capacities of footing for various combinations of the ratio of the depth of the upper layer to the footing width and the ratio of undrained strength of the upper layer to that of the lower. The centrifuge tests indicated that current design practice of calculating failure load of rectangular surface footing under double eccentricity underestimates the centrifuge loading test data. This trend is more marked when the eccentricity becomes larger. The decreasing trend in failure load with an increase of double eccentricity is rather uniquely expressed by a single curve, using a newly defined resultant eccentricity and the diagonal length of the footing base.

• Journal of Pharmaceutical Investigation
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• 제31권3호
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• pp.161-165
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• 2001

Acebutolol (ABT) is almost absorbed after oral administration, but its bioavailability is reduced because of considerable first-pass metabolism in the gastrointestine and liver. The purpose of this study was to report the pharmacokinetic changes of ABT and its metabolite, diacetolol (DAT) after oral administration of acebutolol to control rabbits and rabbits with mild and severe folate-induced renal failure (FIRRs). Both of the area under the plasma concentration-time curve $(AUC^0_{\infty})$ of ABT and DAT were significantly increased in mild (p<0.05) and severe FIRRs (p<0.01), but the $AUC^0_{\infty}$ of DAT was more influenced than that of ABT in severe rabbits. There was a good correlation between serum creatinine and both of $AUC^0_{\infty}$ of ABT and DAT. The elimination half-life of ABT and DAT was significantly prolonged in mild (p<0.05) and severe (p<0.01) FIRRs, but the half-life of DAT was more influenced than that of ABT in severe FIRRs. The results suggest that the dosage of acebutolol should be adjusted according to the degree of renal disorder on the base of the serum creatinine concentration.

• 한국멀티미디어학회논문지
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• 제20권12호
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• pp.1992-1999
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• 2017

This study proposes a decorative typeface which is produced through the concept of trigonometric functions in an open-source programming language known as Processing. First, the theoretical background of Processing and trigonometric functions as well as previous research in this area are analyzed. Second, basic modules of 'V', 'I', 'O', and 'M' were created for use as the final alphabet typeface with the concept of a trigonometric function. Third, a decorative parabolic curve that encircles the base module was created. Finally, the modules created on Processing were edited in Adobe Illustrator to create a typeface set with characters from A to Z. Various artworks using Programming can produce an infinite number of different versions by modifying only some of the variables and codes, and this method can include multimedia features such as text, images, videos, interactive art and various forms of content and media. Therefore, with regard to expression, the possibilities are endless. In this study, I attempt to expand the field of visual culture using programming and computational methodologies. In contrast to the digital typeface production method, which relies on existing graphic tools, this study is meaningful because it expands the range of use of decorative typefaces.

• Steel and Composite Structures
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• 제22권2호
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• pp.353-368
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• 2016

This paper extends our recent work on the fatigue behavior of stud shear connectors in steel and recycled tyre rubber-filled concrete (RRFC) composite beams. A series of 16 fatigue push-out tests were conducted using a hydraulic servo testing machine. Three different recycled tyre rubber contents of concrete, 0%, 5% and 10%, were adopted as main variable parameters. Stress amplitudes and the diameters of studs were also taken into consideration in the tests. The results show that the fatigue lives of studs in 5% and 10% RRFC were 1.6 and 2.0 times greater of those in normal concrete, respectively. At the same time, the ultimate residual slips' values of stud increased in RRFC to highlight its better ductility. The average ultimate residual slip value of the studs was found to be equal to a quarter of studs' diameter. It had also been proved that stress amplitude was inversely proportional to the fatigue life of studs. Moreover, the fatigue lives of studs with large diameter were slightly shorter than those of smaller ones and using larger ones had the risk of tearing off the base metal. Finally, the comparison between test results and three national codes was discussed.

• 한국환경생태학회지
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• 제13권3호
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• pp.271-279
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• 1999

전라북도 장안산의 72군락 지점에서 식물사회학적 조사에 의하여 구분된 10개 군락. 즉 신갈나무 군락, 신갈나무-철쭉꽃 군락, 신갈나무-노린재나무 군락, 신갈나무-졸참나무 군락, 졸참나무 군락, 굴참나무 군락, 서어나무 군락, 물푸레나무 군락, 층층나무 군락, 들메나무 군락에서 풍부도지수, 이질성지수, 균등도지수, 우점도지수를 산출하여 고도, 토양 특성 및 우점종군에 따른 종다양성의 변활르 분석하였으며 종서열-중요치 곡선을 이용하여 각 식물의 우점서열을 결정하고 각 종이 식물군락 내의 자원을 어떻게 분배하고 있는가를 결정하였다 고도, 토양요인(pH, base) 및 우점종의 차이는 삼림의 종 다양성에 영향을 미치는 중요한 변수로서 작용하였으며 우점종군에 따른 다양성의 변화는 지형과 교란에 의하여 영향을 받았다 종서열-중요치 곡선에서 조사된 10개 군락은 대수정규분포에 접근하고 있어서 군락간 약간의 차이는 있지만 대체적으로 어떤 특정 종이 군집 내 자원 공간을 독점하지 않고 적절히 분배하여 사용하고 있었다.

• 한국지진공학회논문집
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• 제22권2호
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• pp.95-101
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• 2018

Diagonally reinforced concrete coupling beams (DRCB) play an important role in coupled shear wall systems since these elements dissipate most of seismic input energy under earthquake loading. For reliable seismic performance evaluation using nonlinear response history analysis, it is important to use an accurate analytical model for DRCBs. In this study, the Pinching4 model is used as a base model to simulate the cyclic behavior of DRCBs. For simulating the cyclic behavior of DRCBs using the Pinching4 model, the analytical parameters for backbone curve, pinching and cyclic deterioration in strength and stiffness should be computed. To determine the proper values of the constituent analytical parameters efficiently and accurately, this study proposes the empirical equations for the analytical parameters using regression analyses. It is shown that the hysteretic behavior of coupling beams can be simulated efficiently and accurately using the proposed numerical model with the proposed empirical equations of model parameters.