The aim of this study was to determine whether the addition of soy isoflavones to dairy ice cream modifies diabetic biomarkers in the type 2 diabetic model mice. Forty male C57BL/6J-ob/ob mice were randomly divided into 4 groups and fed control diet (basal, 7% fat), MS diet (milk ice cream with sugar, 20% fat), MS-SI diet (MS ice cream with 0.01% soy isoflavones, 20% fat), or MF-SI diet (milk ice cream with 0.01% soy isoflavones, 5% fructooligosaccharide, 20% fat) for 12 weeks. Blood response area by glucose tolerance test, plasma levels of glucose, insulin, C-peptide, leptin, and blood $HbA_{1c}$ were not significantly different among all the groups. Concentrations of interleukin-6 and tumor necrosis factor-${\alpha}$ secreted from splenocytes induced by Concanavalin A were not significantly different among all the groups. In conclusion, soy isoflavones supplemented to ice cream did not alter diabetic biomarkers in diabetic type 2 model mice.
Stem diameter variability is an essential inventory result that provides useful information in forest management decisions. Little has been done to explore the modelling potentials of standard deviation (SDD) and coefficient of variation (CVD) of diameter at breast height (dbh). This study, therefore, was aimed at developing and testing models for predicting SDD and CVD in stands of Pinus caribaea Morelet (pine) in south west Nigeria. Sixty temporary sample plots of size $20m{\times}20m$, ranging between 15 and 37 years were sampled, covering the entire range of pine in south west Nigeria. The dbh (cm), total and merchantable heights (m), number of stems and age of trees were measured within each plot. Basal area ($m^2$), site index (m), relative spacing and percentile positions of dbh at $24^{th}$, $63^{rd}$, $76^{th}$ and $93^{rd}$ (i.e. $P_{24}$, $P_{63}$, $P_{76}$ and $P_{93}$) were computed from measured variables for each plot. Linear mixed model (LMM) was used to test the effects of locations (fixed) and plots (random). Six candidate models (3 for SDD and 3 for CVD), using three categories of explanatory variables (i.e. (i) only stand size measures, (ii) distribution measures, and (iii) combination of i and ii). The best model was chosen based on smaller relative standard error (RSE), prediction residual sum of squares (PRESS), corrected Akaike Information Criterion ($AIC_c$) and larger coefficient of determination ($R^2$). The results of the LMM indicated that location and plot effects were not significant. The CVD and SDD models having only measures of percentiles (i.e. $P_{24}$ and $P_{93}$) as predictors produced better predictions than others. However, CVD model produced the overall best predictions, because of the lower RSE and stability in measuring variability across different stand developments. The results demonstrate the potentials of CVD in modelling stem diameter variability in relationship with percentiles variables.
The data used to develop distance-independent individual models for natural mixed forests were collected from 712 remeasured permanent sample plots (25,526 trees) of 10-year periodic from 1990 to 2000 in Baihe Forest Bureau of Changbai Mountains, northeast China. Based on analyzing relationship between diameter increment of individual trees with tree size, competitive status, and site condition, the diameter growth models for individual trees of 15 species growing in mixed-species uneven-aged forest stands, that have simple form, good predicting precision, and easily applicable, were developed using stepwise regression method. The main variables influencing on diameter increment of individual trees were tree size and competition, however, the site conditions were not significantly related with diameter increment. The tree size variables (lnDBH and $DBH^2$) were the most significant and important predictors of diameter growth existing in all 15 growth models. The diameter increment was directly proportional to tree diameter for each species. For the competitive factors in growth model, the relative diameter (RD), canopy closure (P), and the ratio of diameter of subject tree with maximum diameter (DDM) were contributed to the diameter increment at a certain extent. Other measures of stand density, such as basal area of stand (G) and stand density index (SDI), were not significantly influenced on diameter increment. Site factors, such as site index, slope and aspect were not important to diameter increment and excluded in the final models. The total variance explained by the final models of squared diameter increment ($R^2$) for all 15 species ranged from 35% to 72% and these results compared quit closely with those of Wykoff (1990) for mixed conifer stands. Using independent data set, validation measures were evaluated for predicting models of diameter increment developed in this study. The result indicated that the estimated precision was all greater than 94% and the models were suitable to describe diameter increment.
Purpose : Extensive defect of oral and maxillofacial area is usually reconstructed with composite flap including skin paddle. However, if the defects are lined with only skin components, the mucosa's role in mastication and texture are not restored. Furthermore, stiffness and hair-growing prevent denture rehabilitation and good oral hygiene. This study was performed to overcome the disadvantages of composite soft tissue flaps including the skin and to make a model for myo-mucosal flaps. Materials and methods : Buccal mucosa sized $0.5\times1.0\;cm^2$ from New Zealand rabbit (around 1.5kg) was harvested and cultivated by the modification of Rheinwald and Green's keratinocyte culture method. Cultured mucosa was grafted on the fascia of latismus dorsi as form of mucosal sheet. After 7, 10, 14 days, the myomucosal flap was excised and evaluated under light microscope with H & E and immunohistochemical staining. As control group, harvested buccal mucosa from rabbit was transplanted to gracilis muscle(n=6). Results : From 7 days after prelamination, the basal layer of the grafted mucosa resembled that of normal mucosa. As control group, transplanted mucosa had original shape but there's slight inflammatory reaction. Prelaminated mucosa has 19.8$\pm$4.59 cell layers and some samples have more than 20 layers. The expression rate of PCNA was relatively strong (42.9%$\pm$14.1) at the basal layer of grafted mucosa and the laminin was found at the basal layer. On the contrary, prelaminated mucosa at 10 days showed moderate expression rate of PCNA(32.4%$\pm$4.62). We found the mucosal layer was somehow disappeared and there is strong inflammatory reaction. After 14 days prelamination, the grafted oral keratinocytes were almost disappeared and expression of PCNA was not observed. Conclusion : We can make 75 fold large mucosal($3850mm^2$) sheet from small samples of mucosa $(50mm^2)$. Epithelial sheet that grafted on the fascia of muscle underwent differentiation and proliferation. But after 10, 14 days, there was strong inflammatory reaction and the grafted mucosa was destroyed from surface layer. In rabbit model, transfer of fascio-mucosal flap should be done from 7 to 10 days after prelamination.
Sora Kim;Jongsu Yim;Sunjung Lee;Jungeun Song;Hyelim Lee;Yeongmo Son
Journal of Korean Society of Forest Science
/
v.112
no.2
/
pp.209-216
/
2023
This study aimed to use national forest inventory data to develop a forest productivity index and yield prediction model of a Tilia amurensis stand. The site index displaying the forest productivity of the Tilia amurensis stand was developed as a Schumacher model, and the site index classification curve was generated from the model results; its distribution growth in Korea ranged from 8-16. The growth model using age as an independent variable for breast height and height diameter estimation was derived from the Chapman-Richards and Weibull model. The Fitness Indices of the estimation models were 0.32 and 0.11, respectively, which were generally low values, but the estimation-equation residuals were evenly distributed around 0, so we judged that there would be no issue in applying the equation. The stand basal area and site index of the Tilia amurensis stand had the greatest effect on the stand-volume change. These two factors were used to derive the Tilia amurensis stand yield model, and the model's determination coefficient was approximately 94%. After verifying the residual normality of the equation and autocorrelation of the growth factors in the yield model, no particular problems were observed. Finally, the growth and yield models of the Tilia amurensis stand were used to produce the makeshift stand yield table. According to this table, when the Tilia amurensis stand is 70 years old, the estimated stand-volume per hectare would be approximately 208 m3 . It is expected that these study results will be helpful for decision-making of Tilia amurensis stands management, which have high value as a forest resource for honey and timber.
This study was to determine the effect of exercise on the recovery of dopaminergic neuron loss and muscle atrophy in 6-OHDA-induced hemi Parkinson's disease model. Exercise was loaded twice per day for 30 minutes each time, at 5 days after 6-OHDA lesioning and continued for 16 days using a treadmill. Exercise significantly increased the number of tyrosine hydroxylase positive neuron in the lesioned substantia nigra and the expression level of tyrosine hydroxylase in the striatum compared with the control group. To examine which signaling pathways may be involved in the exercise, the phosphorylation of $GSK3{\beta}$ and ERK were observed in the striatum. In the control group, basal level of $GSK3{\beta}$ phosphorylation was less than in both striatum, but exercise increased it. ERK phosphorylation decreased in the lesioned striatum, but exercise recovered it. These findings suggest that exercise inactivates $GSK3{\beta}$ by phosphorylation which may be involved in the neuroprotective effect of exercise on the 6-OHDA-induced cell death. In the exercise group, weight, and Type I and II fiber cross-sectional area of the contralateral soleus significantly recovered and expression of myosin heavy chain and Akt and ERK phosphorylation significantly increased by exercise. These results suggest that exercise recovers Parkinson's disease induced dopaminergic neuron loss and contralateral soleus muscle atrophy.
Seo, Jeong-Ho;Lee, Woo-Kyun;Son, Yowhan;Ham, Bo-Young
Journal of Korean Society of Forest Science
/
v.90
no.6
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pp.725-733
/
2001
In this study, the relationship between growth factors for Pinus densiflora stands in Anmyun-Island was analyzed and dynamic growth model was prepared. A total of 96 sample plots was investigated in which dbh and height of individual trees were measured. From these plot data, quadratic mean dbh, mean height, dominant tree height, stem number per ha, basal area per ha and volume per ha were estimated. Several regression equations between growth factors were derived using NLIN and REG procedure of SAS. And dynamic growth model, in which the equations were interactively linked, was prepared for the prediction of stand growth and yield under different management regime. The predictions of dynamic growth model were found to be coincided with general growth principles. The dynamic growth model was considered as adequate for predicting growth and yield of Pinus densiflora stand in Anmyun-Island. In practice, the dynamic growth model can be applied for predicting the growth and development of stand for various forest treatments and for decision-making in forest management.
Son, Yeong Mo;Kim, So Won;Lee, Sun Jeoung;Kim, Jeong Soo
Journal of Korean Society of Forest Science
/
v.103
no.2
/
pp.264-269
/
2014
The aim of this study was to determine the current distribution area of Robinia pseudoacacia habitat and to estimate its stand yield as well as its carbon stocks. In order to do so, the area of R. pseudoacacia distribution is obtained based on the large-scaled forest type map (1:5,000). Also, Weibull diameter distribution model is used to predict the yield of R. pseudoacacia stands. In addition, carbon emission factor is applied to calculate carbon stocks and removals. To obtain the stand yield of R. pseudoacacia, we developed estimation equation considering growth factors of the stand, e.g. mean diameter, the basal area, maximum and minimun diameter and etc. and tested it to ensure accuracy. Consequently, estimation equation derived from all growth factors have shown significance that could also be used for analysis. Site index was also established to determine the productivity of the forestland that later turned out to be ranging from 16 to 22. Based on these results, stand yield tables were drawn up. R. pseudoacacia is widely distributed in inland areas of Gyeongsang, Chungcheong and Gyeonggi provinces which covers total area of 26,770 ha. And when it is converted into carbon stocks, it amounts to 2,517,598tC with annual carbon uptake of 3.76tC/ha which is comparable to Querqus species that is known to storer large amounts of carbon. Therefore, R. pseudoacacia is also expected to serve as a viable carbon pool that would contribute to the mitigation of climate change. Furthermore, stand yield tables, an outcome of this survey would assist not only in proper management but also in sustainable management policy of R. pseudoacacia.
Pumiceous tuffs occurring in the Beomgockri Group are examined applied-mineralogical characteristics and their controling factors to evaluate their potentials as the adsorption-functional mineral resources. The pumiceous tuffs are diagenetically altered to low-grade zeolitcs and bentonites in the Janggi area. Compositional specialty due to the presence of pumice fragments induces the altered tuffs to exhibit the characteristic adsorption property combined with cation exchange capacity, specific surface area, and acidic pH. Unusual lower pH in the adsorption-functional mineral substances is turned out to be originated from the presence of H-smectite having $H^+$ in the interlayer site of the sheet structure. On account of disordered crystallinity resulting from the exchanged $H^+$ in the interlayer site, the smectite commonly forms crenulated edges in the planar crystal form and exhibits characteristic X-ray diffraction patterns showing comparatively lower intensities of basal spacings including (001) peak than conventional Ca-smectite. Based on the interpretation of paragenetic relations and precursor of the H-smectite, a genetic model of the peculiar clay mineral was proposed. The smectite formation may be facilitated resulting from the precipitation of opal-CT at decreasing pH condition caused by the release of H+ during diagenetic alteration of pumice fragments. Because of the acidic smectite, the low-grade mineral resources from the Beomgockri Group may be applicable to the adsorption industry as the raw materials of acid clays and bed-soil.
Kim, Eun-Sook;Kim, Kyung-Min;Kim, Chong-Chan;Lee, Seung-Ho;Kim, Sung-Ho
Journal of Korean Society of Forest Science
/
v.99
no.6
/
pp.827-835
/
2010
Reliable forest statistics provides important information to meet the UNFCCC. In this respect, the national forest inventory has played a crucial role to provide the reliable forest statistics for several decades. However, the previous forest statistics calculated by administrative district has not provided spatial information in a small scale. Thus, this study focused on developing models to estimate an explicit spatial distribution of forest growing stock. For this, first, stand volume model by stand types was developed using National Forest Inventory(NFI) data. Second, forest type map was integrated with this model. NFI data were used to calculate plot-level stand volume and basal area. The stand types of NFI plot including the species composition, age class, DBH class and crown density class are very crucial data to be connected with forest type map. Finally, polygonlevel stand volume map was developed with spatial uncertainty map. Average stand volume was estimated at 85.7 $m^3$/ha in the study area, and at 95% significance interval it was ranged from 79.7 $m^3$/ha to 91.8 $m^3$/ha.
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