• Nuclear industry
• /
• v.38 no.2
• /
• pp.13-27
• /
• 2018

재생에너지의 활용 가능성이 제한적이고 인구 밀도가 높은 대한민국의 현실을 놓고 볼 때, 원자력은 온실가스 배출 및 공해를 줄이면서도 충분한 전력을 생산하여 공급해줄 수 있는 가장 신뢰할만한 발전 수단이다. 그러나 한국 정부는 원전과 석탄발전소를 단계적으로 폐쇄하고 이를 대체하기 위해서 다양한 재생에너지를 늘리겠다는 정책을 확고하게 고수하고 있다. 그렇지만 에너지 생산 수단을 전환하겠다는 이 정책의 주요 목표는 액화천연가스(LNG) 발전을 대체 수단으로 삼고 있다. 그 이유는 다른 재생에너지들의 대규모 생산 수단을 개발하는 데는 기술적이고 경제적인 난제들이 걸림돌이 되기 때문이다. 그러므로 미래의 에너지 정책을 결정하기에 앞서, 에너지 전환 정책의 구체적인 사항들을 확실한 근거에 기반해서 검토한 후 계획을 수립하는 것이 매우 중요한 일이다. 이 문제에 관해서 우리는 다음과 같은 점들을 검토하였다 (1) 한국이 처해 있는 기술적 경제적인 제약을 전제로 한 재생에너지원의 개발에 대한 정부의 역할, (2) 가스 발전으로 인해 발생할 수 있는 환경적이며 경제적인 문제점들, (3) 원전정책을 지속함으로써 얻을 수 있는 이점과 원전 유지에 대한 장애물. 위와 같은 세 가지 사항을 검토한 결과, 한국이 지니고 있는 지리적 경제적인 제약과 함께 탄소 배출로 인해 발생하는 비용까지 효과적으로 줄여야 한다는 점 등을 감안할 때 천연가스 발전으로 집중하겠다는 한국의 미래 에너지 정책은 친환경적이지 못함은 물론 경제적이지도 않기 때문에 적정한 비율의 재생에너지를 포함하는 원전 정책을 지속하는 것만이 현실적인 성공 가능성이 가장 높다고 보는 것이 우리의 결론이다.

• Molecules and Cells
• /
• v.27 no.1
• /
• pp.89-97
• /
• 2009

We investigate the molecular and cellular etiologies that underlie the deletion of the six amino acid residues (${\Delta}F323-Y328$; ${\Delta}FY$) in human torsin A (HtorA). The most common and severe mutation involved with early-onset torsion dystonia is a glutamic acid deletion (${\Delta}E$ 302/303; ${\Delta}E$) in HtorA which induces protein aggregates in neurons and cells. Even though ${\Delta}FY$ HtorA forms no protein clusters, flies expressing ${\Delta}FY$ HtorA in neurons or muscles manifested a similar but delayed onset of adult locomotor disability compared with flies expressing ${\Delta}E$ in HtorA. In addition, flies expressing ${\Delta}FY$ HtorA had fewer aberrant ultrastructures at synapses compared with flies expressing ${\Delta}E$ HtorA. Taken together, the ${\Delta}FY$ mutation in HtorA may be responsible for behavioral and anatomical aberrations in Drosophila.

• Proceedings of the Korean Society for Bioinformatics Conference
• /
• 2001.08a
• /
• pp.139-149
• /
• 2001

Since 1990, the National Cancer Institute(NCI) has screened more than 60.000 compounds against a panel of 60 human cancer cell lines. The 50-percent growth-inhibitory concentration (GI$_{50}$) values encode unexpectedly rich, detailed information on mechanisms of drug action and drug resistance. Each compound's pattern is like a fingerprint, essentially unique among the many billions of distinguishable possibilities. These activity patterns are being used in conjunction with molecular structural features of the tested agents to explore the NCI's database of more than 460, 000 compounds, and they are providing insight into potential target molecules and modulators of activity in the 60 cell lines. For example, the information is being used to search for candidate anticancer drugs that are not dependent on intact p53 suppressor gene function for their activity. It remains to be seen how effective this information-intensive strategy will be at generating new clinically active agents.s.

• BMB Reports
• /
• v.29 no.2
• /
• pp.99-104
• /
• 1996

Site-directed substitutions were made to change the Ile91 of restriction endonuclease EcoRV to either Val, Ala or Gly to identify the role of Ile91 in recognition and catalysis, since substitution of Ile91 with Leu afforded dramatic effects on the activity and properties of restriction endonuclease EcoRV. These changes alter the size of the hydrophobic side chain at position 91 and thus might have revealed the reason for the altered phenotype of Ile91Leu. However, the properties of Ile91Val and Ile91Ala mutants were much like wild type EcoRV, in both activity and metal ion preference. Ile91Gly had very little activity with either $Mg^{2+}$ or $Mn^{2+}$ as cofactors. To try to understand the unusual $Mn^{2+}$ profile of the Ile91Leu mutant, two double mutants, Ile91Leu;Asp90Asn and Ile91Leu;Glu45Met were created. Both double mutants were seriously disabled by the second amino acid change. Ile91Leu;Glu45Met had some residual activity in the $Mn^{2+}$ reaction buffer, whereas the Ile91Leu;Asp90Asn displayed no detectable activity.

• Journal of Community Nutrition
• /
• v.6 no.2
• /
• pp.78-85
• /
• 2004

Children are the most nutrition sensitive sub-group of a population. The nutritional status of children should be especially emphasized at all levels. This study was performed to investigate the current status, trend, and influencing factors to malnutrition of infants and children in China. The study was mainly based on the China Health and Nutrition Survey which is a longitudinal study conducted in 8 provinces and the data on growth of children under 7 years of age in 9 cities in China. The result of this study showed that one fifth of the children under 5 years of age are still suffering from stunted growth and one tenth suffering from underweight. The nutrition intervention on children under 2 years of age, especially on those under 18 months should be emphasized. Better supplementary food can improve the nutritional status to decrease the prevalence of stunted children. Therefore, the development of supplementary food should be the priority and should be emphasized with breastfeeding.

• Journal of Engineering Education Research
• /
• v.15 no.5
• /
• pp.14-18
• /
• 2012

Shu-gyo-ryoku, a program to enhance students' academic and career skills, was begun in the academic year 2011. Under the new program, "Career Planning" and "Career Design" were introduced as part of the liberal arts education for incoming freshmen. Approximately 500 students majoring in engineering enrolled in "Career Planning" in which they study a "curriculum map" and how it relates to their future fields of employment. The curriculum map illustrates the connections between classes and increases students'understanding of the curriculum structure. In small groups, students discussed the curriculum in order to develop sketches of their career paths. In addition, students answered a career anchor test and though several communicative activities, improved their communication skills. A portfolio system was built into the university network to record the learning history of each student. Students are able to check their learning histories and reflect on the change in themselves during their academic careers.

• Journal of Korean Academy of Nursing
• /
• v.42 no.7
• /
• pp.1079-1086
• /
• 2012

Purpose: The purpose of this study was to develop and evaluate psychometric properties of the instrument, Resuscitation Self-Efficacy Scale for nurses. Methods: This was a methodological study for instrument development and psychometric testing. The initial item pool derived from literature review and experts resulted in 30 items linked to resuscitation self-efficacy. A convenience sample of 509 Korean nurses from eleven academic teaching hospitals participated in a survey to examine psychometric properties of the scale. To examine construct validity, exploratory factor analysis and known-group comparison were used. Cronbach's coefficient alpha was used to determine the scale's internal consistency reliability. Results: The final scale included 17 items with four-component structure termed 'Recognition', 'Debriefing and recording', 'Responding and rescuing', and 'Reporting'. These four factors accounted for 57.5% of the variance. Each subscale and the total scale demonstrated satisfactory internal consistency: .82; .88; .87; .83; and .91 respectively. Experienced nurses reported significantly higher self-efficacy mean scores in both total and subscales compared to new graduate nurses. Conclusion: The Resuscitation Self-Efficacy Scale for nurses yields reliable and valid results in appraising the level of resuscitation self-efficacy for Korean nurses. Further study is needed to test and refine the scale.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2008.10a
• /
• pp.1459-1462
• /
• 2008

In this paper we describe solutions to address critical challenges in direct fabrication of amorphous silicon thin film transistor (TFTs) arrays for active matrix flexible displays. For all flexible substrates a manufacturable handling protocol in automated display-scale equipment is required. For metal foil substrates the principal challenges are planarization and electrical isolation, and management of stress (CTE mismatch) during TFT fabrication. For plastic substrates the principal challenge is dimensional instability management.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2008.10a
• /
• pp.1208-1211
• /
• 2008

We study the amorphous In-Ga-Zn-O thin-film transistors (TFTs) properties under monochromatic illumination ($\lambda=420nm$) with different intensity. TFT off-state drain current ($I_{DS_off}$) was found to increase with the light intensity while field effect mobility ($\mu_{eff}$) is almost unchanged; only small change was observed for sub-threshold swing (S). Due to photo-generated charge trapping, a negative threshold voltage ($V_{th}$) shift is also observed. The photofield-effect analysis suggests a highly efficient UV photocurrent conversion in a-IGZO TFT. Finally, a-IGZO mid-gap density-of-states (DOS) was extracted and is more than an order lower than reported value for a-Si:H, which can explain a good switching properties of the a-IGZO TFTs.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
• /
• 2005.04a
• /
• pp.415-419
• /
• 2005

대수층 저장 및 회수(ASR)기술의 현장 적용성을 평가하기 위하여 경상북도 울릉군 울릉읍 저동천 상류부근에서 양수시험 및 주입시험을 실시하였다. 양수시험결과 투수계수는 $48.7m^2/day$ 이고, 저류계수는 0.009이며, 비양수량은 $158.2m^2/day$로 계산되었다. 또한 시험정과 관측정은 거의 위상차 없이 같은 수위강하 경향을 보여주며 취수정은 관측정보다 평균적으로 10cm 정도 더 높은 수위강하 폭을 보여주는 것으로 미루어 볼 때 시험정과 관측정의 두 지점은 서로 수리지질학적으로 긴밀히 연결되어 있는 하나의 시스템임을 강하게 시사한다. 이외에도 주입시험 결과 암반구간 대수층은 낮은 투수계수를 가질 뿐만 아니라 낮은 저류계수를 가지기 때문에 ASR에 불리한 조건을 가짐을 알 수 있다. 그러나 상부 충적층 구간에서 실시한 주입시험 결과, 두 지점은 긴밀히 연결된 하나의 시스템으로 두 지점의 심부 암반층과의 연결성은 없고, 대신 상부의 높은 투수계수를 가지는 충적층 구간이 두 지점사이에 서로 긴밀히 연결되어 있는 것으로 파악된다. 또한 잔류 수위가 0으로 떨어지는 것으로 볼 때 주입된 주입수는 저장되지 않고 인근의 저동천으로 빠져나가는 것으로 사료된다. 이상의 사실로 볼 때 본 연구지역은 ASR에 불리한 조건을 가지는 지역으로 최종적으로 판단된다.