• Title/Summary/Keyword: Barrier design

Search Result 739, Processing Time 0.024 seconds

Analysis of Commercial Bus Vehicle Collision Accidents (사업용 버스 차량 충돌사고 해석)

  • Han, Inhwan
    • Journal of Korean Society of Transportation
    • /
    • v.32 no.1
    • /
    • pp.63-72
    • /
    • 2014
  • In this paper, characteristics and types of vehicle accidents involving buses that differ from common passenger cars are analyzed. When heavy vehicles are involved in collision accidents, the external impulse conveyed through bus tire from road surface cannot be ignored, so the conventional rigid-body impact model cannot be applied. As a solution, an analysis model which directly considers the tire impulse or considers the bus as moving barrier has been proposed. Also, as there are many instances in which the location of contact point or coefficients related to rotational motion cannot be estimated, utilization of point-mass collision model has been sought. By applying the proposed analysis model to an actual accident case and comparing with the result of the conventional analysis which does not consider the tire impulse, it is shown that the velocity of bus and other values close to the actual amount can be obtained.

Characterization of Bacillus anthracis proteases through protein-protein interaction: an in silico study of anthrax pathogenicity

  • Banerjee, Amrita;Pal, Shilpee;Paul, Tanmay;Mondal, Keshab Chandra;Pati, Bikash Ranjan;Sen, Arnab;Mohapatra, Pradeep Kumar Das
    • CELLMED
    • /
    • v.4 no.1
    • /
    • pp.6.1-6.12
    • /
    • 2014
  • Anthrax is the deadly disease for human being caused by Bacillus anthracis. Instantaneous research work on the mode of infection of the organism revealed that different proteases are involved in different steps of pathogenesis. Present study reports the in silico characterization and the detection of pathogenic proteases involved in anthrax infection through protein-protein interaction. A total of 13 acid, 9 neutral, and 1 alkaline protease of Bacillus anthracis were selected for analysing the physicochemical parameter, the protein superfamily and family search, multiple sequence alignment, phylogenetic tree construction, protein-protein interactions and motif finding. Among the 13 acid proteases, 10 were found as extracellular enzymes that interact with immune inhibitor A (InhA) and help the organism to cross the blood brain barrier during the process of infection. Multiple sequence alignment of above acid proteases revealed the position 368, 489, and 498-contained 100% conserved amino acids which could be used to deactivate the protease. Among the groups analyzed, only acid protease were found to interact with InhA, which indicated that metalloproteases of acid protease group have the capability to develop pathogenesis during B. anthracis infection. Deactivation of conserved amino acid position of germination protease can stop the sporulation and germination of B anthracis cell. The detailed interaction study of neutral and alkaline proteases could also be helpful to design the interaction network for the better understanding of anthrax disease.

Hydrogeological Performance Assessment for Underground Oil Storage Caverns (지하유류비축시설 수리안정성 평가방안)

  • 김천수;배대석;김경수;고용권;송승호
    • The Journal of Engineering Geology
    • /
    • v.7 no.3
    • /
    • pp.229-245
    • /
    • 1997
  • There are Common aspects between the underground oil storage cavern and the radioactive waste disposal facility. Both facilities use appropriately the intrinsic natural berrier characteristics of the rock mass and additionally the engineered barrier system for the long term safety. The geological structures and their hydrogeological characteristics in a faactured rock mass act a major role in the safety and performance of the underground oil storage facility through the design, construction and the operation stages. Because the fracture system distributed in a fractured rock block is complicated owing to their own geometrical and hydrogeological attributes, the hydrogeological perforrmrnce of the facility would depend mainly upon the understandings of their characteristics. This study reviews the uncertainties and key issues which have to be considered to analyse the groundwater flow system in a fractured rock mass and proposes the techniques applicable to characterize the hydrogeological parameter.

  • PDF

Functionally Gradient Materials (FGMs) for Improved Thermo-mechanical Properties (열.기계적 특성 향상을 위한 경사기능 재료 (FGM))

  • 박성용;김진홍;김문철;박찬경
    • Journal of Powder Materials
    • /
    • v.11 no.1
    • /
    • pp.8-15
    • /
    • 2004
  • The basic concept of functionally gradient materials (FGM) is to fabricate materials type having possibilities of applications in various fields by changing their intrinsic properties with continuous gradient. The present communication has reviewed the developments and applications of various FGMs designed for improved thermo-mechanical properties, in which the thermal protective and wear resistant materials are especially focused. Effects of thermo-mechanical properties and limits of FGMs designed for high temperature applications were mainly understood in terms of residual stress evolved from the design and fabrication. In addition, FGMs applied in structural parts were also introduced and discussed in terms of typical fabrication method for FGMs.

Synthetic Strategies for High Performance Hydrocarbon Polymer Electrolyte Membranes (PEMs) for Fuel Cells (고성능 탄화수소계 고분자 전해질막의 합성 전략)

  • Lee, So Young;Kim, Hyoung-Juhn;Nam, Sang Yong;Park, Chi Hoon
    • Membrane Journal
    • /
    • v.26 no.1
    • /
    • pp.1-13
    • /
    • 2016
  • Fuel cells are regarded as a representative energy source expected to replace fossil fuels particularly used in internal combustion engines. One of the most important components is polymer electrolyte membranes (PEMs) acting as a proton conducting barrier to prevent fuel gas crossover. Since water channels act as proton pathways through PEMs, many researchers have been focused on the 'good phase-separation of hydrophilic moiety' which ensures high water retention under low humidity enough to keep the water channel for good proton conduction. Here, we summarized the strategies which have been adopted to synthesize sulfonated PEMs having high proton conductivities even under low humidified conditions, and hope this review will be helpful to design high performance hydrocarbon PEMs.

BCP utilizing Disaster Recovery-System for the Protection of the Information System Design (효율적인 정보자산 보호를 위한 BCP 활용 재해복구시스템 설계)

  • Kim, Hyun-Joo;Lee, Soo-Jong;Shin, In-Chul
    • Journal of the Korea Society of Computer and Information
    • /
    • v.18 no.7
    • /
    • pp.93-100
    • /
    • 2013
  • The ensuing disaster brought by the massive earthquake and tsunami in the northeastern region of Japan in 2011 placed Japan, one of the three most advanced economic powers in the world, in a defenseless state. With the rising interest in disaster recovery, Korea is also making efforts to provide technological support for barrier-free system operation 24 hours a day, 365 days a year. To protect intelligence assets efficiently, this study draws a job performance plan to prepare for disasters, which systemizes methodical coping capabilities into business plans when disasters occur. Moreover, this study systemizes the job performance plan to allow members easy access to information that will help them proceed without confusion in emergencies. This plant is intended to protect intelligence assets of an organization clearly and promptly.

A Study on the design and fabrication of Pluggable Lens for Optical PCB Interconnection (광 PCB 접속용 플러거블 렌즈의 설계 및 제작 연구)

  • Kim, Jung Hoon;Lee, Tae Ho;Kim, Dong Min;Jeong, Myung Yung
    • Journal of the Microelectronics and Packaging Society
    • /
    • v.21 no.1
    • /
    • pp.25-29
    • /
    • 2014
  • In this study, an optical PCB was proposed which can overcome the limitations of the conventional PCB, and a new structure with pluggable lens was considered for a high-efficient passive alignment. The structure was a lens-added optical waveguide for the improvement of misalignment between the lens and the waveguide in the alignment. Also, as it had a barrier-type structure to prevent the surface damage of the lens by desorption, the high-efficient passive alignment can be realized. The structure was designed by optimizing the simulation and the fabrication process of the pluggable lens structure was conducted using the repetitive photolithography and the thermal reflow. The optical waveguide with the lens-integrated pluggable interconnection was fabricated by the imprint process using the polydimethylsiloxane(PDMS) replica mold. Therefore, we confirmed the possibility of pluggable lens-added optical waveguide structure fabrication for high-efficient passive alignment.

Characteristics of Percutaneous Absorption for Three Kinds of Phthalate (Phthalate 3종에 대한 경피투과 특성 연구)

  • Jung, Duck-Chae;Yoon, Cheol-Hun;Um, Mi-Sun;Hwang, Hyun-Suk;Baek, Jung-Hun;Choi, Jin-Ho
    • Journal of Environmental Health Sciences
    • /
    • v.39 no.4
    • /
    • pp.360-368
    • /
    • 2013
  • Objectives: Phthalates are used in a large variety of products including as coatings of pharmaceutical tablets, film formers, stabilizers, dispersants, emulsifying agents, and suspending agents. They have been the subject of great public concern in recent years. The extensive uses of this material have attracted attention and issues regarding its safety have been raised. Methods: In this study, three types of phthalate skin permeation were studied using matrixes such as ointments, creams and lotions in vitro. The absorption of phthalate diesters [Dimethyl phthalate (DMP), Di-n-propyl phthalate (DPP) and Di-n-pentyl phthalate (DNPP)] using film former has been measured in vitro through rat skin. Epidermal membranes were set up in Franz diffusion cells and their permeability to PBS measured in order to establish the integrity of the skin before the phthalates were applied to the epidermal surface. Results: Absorption rates for each phthalate ester were determined and permeability assessment made to quantify any irreversible alterations in barrier function due to contact with the esters. Types of phthalate in vitro experimental results quickly appeared in the following order DMP > DPP ${\geq}$ DNPP. Conclusions: In the experimental results, lotion> cream> ointment, and the permeation rate of lotion with a great amount of moisture was the fastest. Skin permeation rate is generally influenced by the chemical characteristics of a given chemical, such as molecular weight and lipophilicity. As the esters became more lipophilic and less hydrophilic, the rate of absorption decreased.

Impact of Central Line Insertion Bundle on the Adherence of Bundle and Central Line-Associated Bloodstream Infections in the Operating Room (수술실에서 중심정맥관 삽입 시 번들적용이 중심정맥관 관련 혈류감염에 미치는 영향)

  • Shin, Eun Jeong;Jeong, Jae Sim;Choi, Sang Ho;Huh, In Young
    • Journal of Korean Biological Nursing Science
    • /
    • v.18 no.4
    • /
    • pp.257-263
    • /
    • 2016
  • Background: This study purposed to examine how the incidence of the central line-associated bloodstream infection (CLABSI) in a operating room (OR) is affected by bundle application on central line insertion (CLI) practice. Methods: The study design was a pretest-posttest experimental trial. The subjects were 83 patients before the bundle application on CLI and 70 patients after. Results: The compliance(%) of bundle on CLI of among those who observed all of the five items increased from 7.2% before the intervention to 72.9% after. By items, compliance with the maximal barrier precaution was 100% for the use of a mask and cap before and after the intervention, but increased from 73.5% before the intervention to 88.6% after for the hand hygiene, from 73.5% to 88.6% for the use of a sterile gown, and from 9.6% to 75.7% for the use of a sterile large drape covering the whole body. CLABSI did not happen on CLI either before or after the application of the bundle intervention. Conclusion: Bundle application increased compliance with the use of a sterile gown and the use of a sterile large drape. However, its effect in the prevention of CLABSI was not clear probably due to the short period of intervention in a single hospital.

Evaluation on Fire Spread Speed of Standard Rack in Korea for Performance based Fire Extinguishing System (성능위주 소화설비 적용을 위한 표준랙크의 화재확산속도 평가)

  • Cho, Gyu-Hwan;Yeo, In-Hwan
    • Fire Science and Engineering
    • /
    • v.30 no.6
    • /
    • pp.84-91
    • /
    • 2016
  • In case of fire, vertically and intensively loaded rack warehouses are faced with a severe status due to the rapid increase in fires. In this regard, there have been trials to prevent fires from spreading by applying fire extinguishing systems, such as ESFR and In-Rack Sprinklers, vertical and horizontal barriers, etc.; however, it is difficult to calculate and design proper fire extinguishing systems caused by various composition conditions, such as the size and loading density of the rack, types of loading commodities, etc. Therefore, in this study, a standard rack was manufactured, incorporating a rack warehouse in Korea by site investigations, surveys, etc. In addition, a full scale fire test was executed to check the fire characteristics depending on the conditions of the ignition points. As a result, the extracted fire spread speed is expected to be utilized as a reference for performance comparisons of the fire extinguishing systems to be developed and applied in the future.