• Title/Summary/Keyword: Barrier Effect

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Characteristics of Magnetic Tunnel Junctions Comprising Ferromagnetic Amorphous NiFeSiB Layers (강자성 비정질 NiFeSiB 자유층을 갖는 자기터널접합의 스위칭 특성)

  • Hwang, J.Y.;Rhee, S.R.
    • Journal of the Korean Magnetics Society
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    • v.16 no.6
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    • pp.279-282
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    • 2006
  • Magnetic tunnel junctions (MTJs), which consisted of amorphous ferromagnetic NiFeSiB free layers, were investigated. The NiFeSiB layers were used to substitute for the traditionally used CoFe and/or NiFe layers with the emphasis being given to obtaining an understanding of the effect of the amorphous free layer on the switching characteristics of the MTJs. $Ni_{16}Fe_{62}Si_{8}B_{14}$ has a lower saturation magnetization ($M_{s}:\;800\;emu/cm^{3}$) than $Co_{90}Fe_{10}$ and a higher anisotropy constant ($K_{u}:\;2700\;erg/cm^{3}$) than $Ni_{80}Fe_{20}$. The $Si/SiO_{2}/Ta$ 45/Ru 9.5/IrMn 10/CoFe $7/AlO_{x}/CoFeSiB\;(t)/Ru\;60\;(in\;nanometers)$structure was found to be beneficial for the switching characteristics of the MTJ, leading to a reduction in the coercivity ($H_{c}$) and an increase in the sensitivity resulted from its lower saturation magnetization and higher uniaxial anisotropy. Furthermore, by inserting a very thin CoFe layer at the tunnel barrier/NiFeSiB interface, the TMR ratio and switching squareness were improved more with the increase of NiFeSiB layer thickness up to 11 nm.

Effect of Curcumin Derivatives on Heme Oxygenase-1 Expression in HT22 Cells (HT22 세포에서 Curcumin 유도체가 Heme Oxygenase-1 발현에 미치는 효과)

  • Cheong, Yong-Kwan;Lee, Yun-Jung;Chun, Hyun-Ja;Ryu, Il-Hwan;Jee, Yeon-Ju;Chae, Gwon-U;Kim, Young-Sook;Shon, Ji-Ue;Kang, Hyun-Gyu;Lee, Sung-Hee;An, Ren-Bo;Chung, Hun-Taeg;Pae, Hyun-Ock
    • YAKHAK HOEJI
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    • v.55 no.4
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    • pp.319-323
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    • 2011
  • Curcumin, of which a critical characteristic is the capacity of crossing the blood-brain barrier, has been reported to induce the expression of neuroprotective heme oxygenase (HO)-1. The aim of this study is to compare HO-1-inducing capacity and neuroprotective activity of curcumin, its demethoxy (demethoxycurcumin, DMC; bis-demethoxycurcumin, BDMC) and hydrogenated derivatives (tetrahydrocurcumin, THC) in mouse hippocampal HT22 cells. Curcumin attenuated glutamate-induced cell death through HO-1 expression. DMC lacking a methoxy group on one of the aromatic rings possessed slightly lower activity in HO-1 expression and neuroprotection than curcumin. Similarly, BDMC, which lacks two methoxy groups on both of the aromatic rings, showed less activity than curcumin. These findings suggest that the presence of methoxy groups on the aromatic ring is required to enhance neuroprotective HO-1 expression. The reduction of the diarylheptadienone chain of curcumin by hydrogen, as in THC, was accompanied by a complete loss of ability to induce HO-1 expression and neuroprotection, suggesting that the conjugated double bonds of the central seven-carbon chain of curcumin may be essential for its ability to induce neuroprotective HO-1 expression. Our findings may provide useful information for further development of neuroprotective HO-1 inducers.

THE EFFECT OF THE BIORESORBABLE COLLAGEN MEMBRANE ON THE REGENERATION OF BONE DEFECT BY USING THE MIXTURE OF AUTOGRAFT AND XENOGRAFT BONE

  • Lee Jung-Min;Kim Yung-Soo;Kim Chang-Whe;Han Jung-Suk
    • The Journal of Korean Academy of Prosthodontics
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    • v.41 no.3
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    • pp.325-341
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    • 2003
  • Statement of problem: In cases where bony defects were present, guided bone regenerations have been performed to aid the placement of implants. Nowadays, the accepted concept is to isolate bone from soft tissue by using barrier membranes to allow room for generation of new bone. Nonresorbable membranes have been used extensively since the 1980's. However, this material has exhibited major shortcomings. To overcome these faults, efforts were made to develop resorbable membranes. Guided bone regenerations utilizing resorbable membranes were tried by a number of clinicians. $Bio-Gide^{(R)}$ is such a bioresorbable collagen that is easy to use and has shown fine clinical results. Purpose: The aim of this study was to evaluate the histological results of guided bone regenerations performed using resorbable collagen membrane($Bio-Gide^{(R)}$) with autogenous bone, bovine drived xenograft and combination of the two. Surface morphology and chemical composition was analyzed to understand the physical and chemical characteristics of bioresorbable collagen membrane and their effects on guided bone regeneration. Material and methods: Bioresorbable collagen membrane ($Bio-Gide^{(R)}$), Xenograft Bone(Bio-Oss), Two healthy, adult mongrel dogs were used. Results : 1. Bioresorbable collagen membrane is pure collagen containing large amounts of Glysine, Alanine, Proline and Hydroxyproline. 2. Bioresorbable collagen membrane is a membrane with collagen fibers arranged more loosely and porously compared to the inner surface of canine mucosa: This allows for easier attachment by bone-forming cells. Blood can seep into these spaces between fibers and form clots that help stabilize the membrane. The result is improved healing. 3. Bioresorbable collagen membrane has a bilayered structure: The side to come in contact with soft tissue is smooth and compact. This prevents soft tissue penetration into bony defects. As the side in contact with bone is rough and porous, it serves as a stabilizing structure for bone regeneration by allowing attachment of bone-forming cells. 4. Regardless of whether a membrane had been used or not, the group with autogenous bone and $Bio-Oss^{(R)}$ filling showed the greatest amount of bone fill inside a hole, followed by the group with autogenous bone filling, the group with blood and the group with $Bio-Oss^{(R)}$ Filling in order. 5. When a membrane was inserted, regardless of the type of bone substitute used, a lesser amount of resorption occurred compared to when a membrane was not inserted. 6. The border between bone substitute and surrounding bone was the most indistinct with the group with autogenous bone filling, followed by the group with autogenous bone and $Bio-Oss^{(R)}$ filling, the group with blood, and the group with $Bio-Oss^{(R)}$ filling. 7. Three months after surgery, $Bio-Gide^{(R)}$ and $Bio-Oss^{(R)}$ were distinguishable. Conclusion: The best results were obtained with the group with autogenous bone and $Bio-Oss^{(R)}$ filling used in conjunction with a membrane.

Effect of laser-dimpled titanium surfaces on attachment of epithelial-like cells and fibroblasts

  • Lee, Dong-Woon;Kim, Jae-Gu;Kim, Meyoung-Kon;Ansari, Sahar;Moshaverinia, Alireza;Choi, Seong-Ho;Ryu, Jae-Jun
    • The Journal of Advanced Prosthodontics
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    • v.7 no.2
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    • pp.138-145
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    • 2015
  • PURPOSE. The objective of this study was to conduct an in vitro comparative evaluation of polished and laser-dimpled titanium (Ti) surfaces to determine whether either surface has an advantage in promoting the attachment of epithelial-like cells and fibroblast to Ti. MATERIALS AND METHODS. Forty-eight coin-shaped samples of commercially pure, grade 4 Ti plates were used in this study. These discs were cleaned to a surface roughness (Ra: roughness centerline average) of 180 nm by polishing and were divided into three groups: SM (n=16) had no dimples and served as the control, SM15 (n=16) had $5-{\mu}m$ dimples at $10-{\mu}m$ intervals, and SM30 (n=16) had $5-{\mu}m$ dimples at $25-{\mu}m$ intervals in a $2{\times}4mm^2$ area at the center of the disc. Human gingival squamous cell carcinoma cells (YD-38) and human lung fibroblasts (MRC-5) were cultured and used in cell proliferation assays, adhesion assays, immunofluorescent staining of adhesion proteins, and morphological analysis by SEM. The data were analyzed statistically to determine the significance of differences. RESULTS. The adhesion strength of epithelial cells was higher on Ti surfaces with $5-{\mu}m$ laser dimples than on polished Ti surfaces, while the adhesion of fibroblasts was not significantly changed by laser treatment of implant surfaces. However, epithelial cells and fibroblasts around the laser dimples appeared larger and showed increased expression of adhesion proteins. CONCLUSION. These findings demonstrate that laser dimpling may contribute to improving the peri-implant soft tissue barrier. This study provided helpful information for developing the transmucosal surface of the abutment.

Effect of Modified Atmosphere Packaging on Preservation of Pumpkin Rice Cake (호박 설기떡의 저장성에 미치는 변형기체포장의 영향)

  • Moon, Ki-Bok;Kim, Hwan-Ki;An, Duck-Soon;Lee, Dong-Sun
    • Food Science and Preservation
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    • v.17 no.6
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    • pp.908-913
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    • 2010
  • Modified atmosphere packaging (MAP) was evaluated for the storage of pumpkin rice cake as a means of preserving quality and extending shelf-life. Retail-sized amounts of rice cake were packaged in trays under different modified atmosphere conditions (air, vacuum, 60% $CO_2$/40% $N_2$ and 100% $CO_2$) using gas-barrier plastic film; control was in air-permeable stretch wrap. The packages were stored at $20^{\circ}C$ with periodical measurement of package atmosphere and cake quality attributes. The modified atmosphere packages of 60% $CO_2$/40% $N_2$ and 100% $CO_2$ inhibited the growth of molds/yeasts completely and significantly retarded the growth of aerobic bacteria. All the packages except that of 100% $CO_2$ showed the reduction of internal $O_2$ concentration and increase of the $CO_2$ with storage time due to the microbial activity. There has been slight decrease of $CO_2$ concentration for 60% $CO_2$/40% $N_2$ and 100% $CO_2$ packages just after start of the storage possibly due to dissolution of headspace $CO_2$ into the cake. Any MAP conditions did not affect the retrogradation of the rice cake. Surface color of the cake within affordable microbial quality limit was not affected significantly by packaging conditions.

Exploring the Effects of Task Language and Complexity in College Students' Web Searching (질의 언어 및 복잡성이 대학생의 웹 정보탐색에 미치는 영향에 관한 연구)

  • Shim, Wonsik;Ahn, Hye-yeon;Byun, Jeayeon
    • Journal of the Korean Society for Library and Information Science
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    • v.49 no.2
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    • pp.51-73
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    • 2015
  • The Web now provides instant access to an unprecedented amount of information that was unthinkable even 20-30 years ago. However, the full potential of the contents available through the Internet can only be realized when one can speak and understand foreign languages, especially English which accounts for more than half of web contents. In this study, we try to investigate the effect of search task languages and task complexity on searching performance. A total of thirty students enrolled at a top private university in Korea were recruited as study subjects. We set up a quasi-experimental design in which thirty subjects are randomly assigned to a set of eight different search tasks containing an equal number of simple and complex tasks and an equal number of tasks in Korean and in English. The results show that there is a significant difference between simple and complex tasks in terms of SERP time, number of queries used, correctness of results and total search time. However, task language does not seem to have affected search performance for this study group. In addition, students with high English proficiency test scores show comparable search performance in English tasks compared with lower test scores. But we note differences in behavioral patterns (different search engines used and search tactics) among the study participants.

Structural and photoelectrical properties of copper phthalocyanine(CuPc) thin film on Si substrate by thermal evaporation (Si 기판위에 열증착법으로 제조한 copper phthalocyanine(CuPc) 박막의 구조 및 광전특성)

  • Lee, Hea-Yeon;Jeong, Jung-Hyun;Lee, Jong-Kyu
    • Journal of Sensor Science and Technology
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    • v.6 no.5
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    • pp.407-413
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    • 1997
  • The crystallized CuPc(copper phthalocyanine) film on a p-type <100> Si substrate is prepared at the substrate temperature of $300^{\circ}C$ by thermal evaporation. X -ray diffraction analysis showed the CuPc film to have a-axis oriented structure. For the measurement of photovoltaic characteristics of the CuPc/Si film and the Si substrate, a transverse current-voltage (I-V) curve is observed. In the dark, the Au/Si junction is shown to be ohmic contact. However, under illumination, a photovoltaic effect is not observed. The I-V curve in the dark indicates that the CuPc film on Si may form an ohmic contact. Since the CuPc film is a p-type semiconductor, the CuPc/p-Si junction has no barrier at the interface. Under illumination, the CuPc/Si junction shows a large photocurrent comparing with that of the wafer. The result indicates that the CuPc layer plays an important role in the photocarrier generation under red illumination (600 nm). The CuPc/Si film shows the photo voltaic characteristics with a short-circuit photocurrent ($J_{sc}$) of $4.29\;mA/cm^{2}$ and an open-circuit voltage ($V_{oc}$) of 12 mA.

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The effect of career barrier and major satisfaction on the career preparation behavior in the group of security major college students (경호학전공대학생의 진로장벽과 전공만족도가 진로준비행동에 미치는 영향)

  • Beak, Kyeong-Hwa;Yoo, Kyoung-Ho
    • Korean Security Journal
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    • no.29
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    • pp.115-137
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    • 2011
  • The purpose of this study was to look into impacts of career barriers and college major satisfactions on career preparation behaviors of Security major college students. The subjects of this study were collected among 200 security major students attending universities in Choungnam and Junnam Provinces, and 170 out of 200 were analyzed. Based on collected data, exploratory factor analysis, correlation analysis, multiple regression analysis, and one-way ANOVA were conducted using SPSS 18.0. According to the result, career barriers showed negative correlations on career preparation behaviors, and self-concept clarity deficiency showed significant impact on it. College major satisfactions showed positive correlations, and major satisfaction showed significant impact on it. Also result shows college junior and senior students experience less career barriers compare to freshman and sophomore students, and college junior and senior students were more satisfied on the college major satisfactions as well. The study has found important implications of impacts of career barriers and college major satisfaction on career preparation behaviors. In long term, the finding of the study seem to provide useful insights for security major students and Human Resource Personnel to execute the process of career preparations and related counseling effectively.

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A Study on the Effects of Social Reinforcement in Peer groups on Children's Dental Health Behavior (또래집단의 사회적 강화가 아동의 구강보건행태에 미치는 효과)

  • Lee, Nan-Hee;Park, In-Hyae
    • Journal of the Korean Society of School Health
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    • v.13 no.1
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    • pp.117-129
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    • 2000
  • The relationships between children's health behavior and variables that effect children's health behavior has been investigated in a number of previous studies. This study was conducted to examine the effects of a peer's social reinforcement on children's dental health behavior in an elementary school. The research design was a nonequivalent pre and post-test quasi-experimental design and the study subjects with one hundred and thirteen eight to nine years old children, and their mothers (57 experimental group, 56 control group) were selected as a study group. Subjects were selected by the convenience sampling method. The study was carried out in an elementary school in Namwon city, Korea, from the 26th of April to the 12th of June in 1999. Data were collected in both the pre and post-test portions. Using the "Health Belief Model", each item of the questionnaire for measurement of dental health behavior was modified and administered for the children and their mothers. The questionnaire for the measurement of dental health behavior was developed by Oh, Y.B.(1994). The Cronbach's ${\alpha}$ of the questionnaire for children were .81, and for the mother were .79. In this study, the health belief model consists of "perceived susceptibility", "perceived seriousness", "perceived barrier", "perceived salience", and "perceived benefit". The questionnaire for the children was composed of 37 items, and the questionnaire for the mother was composed of 40 items. Data were analyzed by frequency, ${\chi}^2-test$, ANOVA, Pearson's Correlation, and multiple regression analysis by a SAS program. The results of this study were summarized as follows ; 1. The first hypothesis that the experimental group would have more change in the frequency of brushing per week than that of control group was accepted(t=3.817, p=0.000). Mean tooth brushing scores in the experimental group improved significantly from pre-test to post-test, but in the control group there was no significant improvement in tooth brushing scores. 2. The second hypothesis that the experimental group would have more change in score of dental health behavior than that of control group was accepted(benefit : t=2.804, p=0.006, salience: t=2.608, p=0,010). An evaluation between the experimental group and the control group showed significant change from pre-test to post-test in health behavior scores. 3. The third hypothesis that higher scores of social reinforcement would create more change in the scores of tooth brushing frequency in the experimental group was accepted(${\beta}$=0.169, p=0.000. Multiple regression was used to examine the peer's social reinforcement scores and the relative influence of significant variables in previous ANOVA and Pearson's correlation test on children's frequency of brushing during the post-test. The results of the study indicated that the combination of social reinforcement of peers with variables pertaining to mother and householder were significantly related and effectively improved a child's tooth brushing.

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Bactericidal Efficacy of Non-thermal DBD Plasma on Staphylococcus aureus and Escherichia coli (비열 유전체장벽방전 플라즈마의 포도상구균 및 대장균 살균효과)

  • Kim, Keyyoung;Paik, Namwon;Kim, Yonghee;Yoo, Kwanho
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.28 no.1
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    • pp.61-79
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    • 2018
  • Objectives: The objective of this study was to examine the effect of non-thermal dielectric barrier discharge(DBD) plasma on decontamination of Staphylococcus aureus(S. aureus) and Escherichia coli(E. coli) as common pathogens. Methods: This experiment was carried out in a chamber($0.64m^3$)designed by the authors. The plasma was continuously generated by a non-thermal DBD plasma generator(Model TB-300, Shinyoung Air tech, Korea). Suspensions of S. aureus and E. coli of 0.5 McFarland standard($1.5{\times}10^8CFU/mL$) were prepared using a Densi-Check photometer(bio $M{\acute{e}}rieux$, France). The suspensions were diluted1:1000 in sterile PBS solutions(approximately$10^{4-5}CFU/mL$) and inoculated on tryptic soy agar(TSA) in Petri dishes. The Petri dishes(80mm internal diameter)were exposed to the non -thermal DBD plasma in the chamber. Results: The results showed that 95% of S. aureus colonies were killed after a six-hour exposure to the DBD plasma. In the case of E. coli, it took two hours to kill 100% of the colonies. The gram-negative E. coli had a greater reduction than the gram-positive S. aureus. This difference may be due to the structure of their cell membranes. The thickness of gram-positive bacteria is greater than that of gram-negative bacteria. The S. aureus is more resistant to DBD plasma exposures than is E. coli. It should be noted that average concentrations of ozone, a byproduct of the DBD plasma generator, were monitored throughout the experiment and the results were well below the criteria, 50 ppb, recommended by the Korean Ministry of the Environment. Thus, non-thermal DBD plasma is deemed safe for use in hospital and public facilities. Conclusions: There was evidence that non-thermal DBD plasma can effectively kill S. aureus and E. coli. The results indicate that DBD plasma technology can greatly contribute to the control of infections in hospitals and other public and private facilities.