• Title/Summary/Keyword: Bangkibokryeong-tang(Fanjifuling-tang)

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A Case Report of Bangkibokryeong-tang on Antibiotic Resistant Urinary Tract Infection of Cerebral Vascular Accident Patient (뇌졸중 환자의 요로감염에 대한 방기복령탕 치험 1례)

  • Hwang, Yun-Kyeong;Kim, Won-Ill
    • Herbal Formula Science
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    • v.23 no.1
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    • pp.141-150
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    • 2015
  • Objectives : This study is to report the effects of Bangkibokryeong-tang(Fanjifuling-tang(BBT)) on stroke patient with Urinary tract infection.(UTI) Methods : A stroke patient diagnosed as UTI was treated with BBT (防己茯笭湯) at one-month intervals. We observed body temperature, amount of urine and recorded photographs of any changes during the treatment period. Treatment efficacy was assessed using urinary analysis. Results : After the treatment, there was improvement in urine analysis. And the symptoms of UTI and her conditions got better. Conclusion : The report suggests that BBT is effective in controlling various symptoms related to UTI with antibiotic resistance on stroke patient.

The Effects of Bangkibokryeong-tang on Papain-induced OsteoArthritis C57BL/10 Mouse (방기복령탕(防己茯苓湯)이 papain으로 유도된 생쥐의 골관절염에 미치는 영향)

  • Park, In-Sun;Yoon, Il-Ji;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.1
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    • pp.25-49
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    • 2013
  • Objectives : This study was carried out to know the anti-osteroarthritic effects of Bangkibokryeong-tang(Fanjifuling-tang(BBT)) on the papain-induced osteoarthritis C57BL/10 mouse. Methods : Osteoarthritis was induced by injection of papain(6 ${\mu}l$) into knee joint of mouse. Osteoarthritic mice were divided into 4 groups(normal, control, joins(R), BBT). The injection did not fit the normal group. A week later, after the injection of papain, control group was taken normal saline 200 ${\mu}l$, positive control group was taken joins(R)(100 mg/kg), treated group was taken extract of Bangkibokryeong-tang(Fanjifuling-tang(BBT))(400 mg/kg). After then, we examined hepatotoxicity, nephrotoxicity, inflammation cytokines, expression of inflammation factor mRNA, hemotology, histology through the micro CT-arthrography, and etc. Results : 1. Hepatotoxicity and nephrotoxicity have not expressed. 2. The levels of IL-$1{\beta}$, TNF-${\alpha}$, IL-6, MCP-1, Thromboxane B2, Leukotriene B4, Prostaglandin E2 in serum were significantly decreased. 3. In hematology, the levels of neutrophils and monocytes were significantly decreased. 4. The expression of inflammation factor mRNA like TNF-${\alpha}$ and IL-6, COX-2, iNOS-II were significantly inhibited. 5. In micro CT-arthrography, cartilage volume was less decreased. 6. The degree of osteoarthritis induced damage of joint of BBT group is low in histopathologic observation(hematoxylin&eosin(H&E), Safranin-O). Conclusions : According to this study, BBT has effect of anti-osteoarthritis. Further clinical research for the cartilage protective effect is necessary.