• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.2
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• pp.59-70
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• 2006

Objective : This study was performed to investigate the Anti-Inflammatory Effects of WooBangHaeGiTang on the Allergic Contact dermatitis. Method : Contact hypersensitivity assay, video microscope, WBC count, RBU count, neutrophil ratio, lymphpcyte ratio and GOT & GPT were measurd. Result : 1. At Contact hypersensitivity Aasay, at 24 hours after Control group & Sample group showed appreciably more ear swelling than Normal group, at 48 hours after Control group showed more ear swelling than Normal group & Sample group, at 72 hours after Control group & Sample group showed more ear swelling than Normal group 2. Regarding the number of WBC, at 24 or 48 hours after There are no significant difference among Normal group, Control group. Sample group, at 72 hours after Sample group showed more WBC than Control group. 3. Regarding the number of RBC, at 24 hours after Control group showed more RBC than Normal group, at 48 hours after Control group & Sample group showed more RBC than Normal group. at 72 hours after Control group showed more RBC than Normal group. 4. Regarding the percentage of neutrophil in WBC, at 24 & 48 hours after Control group & Sample group showed higher percentage than Normal group. 5. Regarding the percentage of Lymphocyte in WBC, at 24 hours after Sample group showed lower percentage than Normal group, at 48 hours after Sample group & Control group showed lower percentage than Normal group. 6. Regarding the GOT & GPT in blood, the GOT & GPT are in Normal scale, so there are no Hepatotoxicity in Normal group, Control group, Sample group. Conclusions : According to above experiments, WooBangHaeGiTang have some anti allergy effects on allergic contact dermatitis.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.1
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• pp.115-126
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• 1996

In the time optimal control problem, bang-bang control has been used becaese it is the theoretical time minimum solution. However, to improve tracking speed performance in the time optimal control, it is important to select a switching point accurately which makes the velocity zero near the target track. But it is not easy to select the swiching point accurately because of the damping coefficient variation and uncertainties of modeling an actual system. The Adaptive model following control(AMFC) is implemented to relieve the difficulty and inconvenience of this task. The AMFC and make the controlled plant follow as closely as possible to a desired reference model whose switching point can be calculated easily and accurately, assuring the error between the states of the reference model and those of the controlled plant appoaches zero. The hybrid control method composed of AMFC and PID is applied to a tracking actuator of the magneto optical disk drive(MODD) in random access devices to improve its slow tracking performance. According to the simulaion and experimental results, the average tracking time as small as 20ms is obtained for a 3.5 magneto-optical disk drive. The AMFC also can be applied for other random access devices to improve the average tracking performance.

• The Journal of Internal Korean Medicine
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• v.31 no.2
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• pp.331-345
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• 2010

Objectives : This study was designed to investigate the effects of Saenggantanggami-bang (SG) on nonalcoholic fatty liver disease. Methods : HepG2 cells were used in an in vitro model. HepG2 cells were divided into three groups. The Normal group was incubated with no fatty acid. The Control group was incubated with 1mM palmitic acid to introduce fat overloading. The PA-SG group was incubated with 1mM palmitic acid and various concentrations of Saenggantanggami-bang (SG). Cell viability and cytotoxicity were analyzed by MTT assay and LDH assay. Intracellular triglyceride (TG) levels, reactive oxygen species (ROS) levels, ATP amount, and GST activity were measured. Cell death pattern and protective effect of SG on cell death were studied by DNA fragmentation and caspase-3 intensity (western blot). Results : Compared with the Control group, cell viability of the PA-SG group significantly increased (P<0.01), cytotoxicity of the PA-SG group decreased (P<0.01), and intracellular TG levels and ROS levels of the PA-SG group decreased (P<0.05). In DNA fragmentation assay, necrotic pattern was observed and DNA fragment decreased in the PA-SG group. In western blot, apoptotic pattern was observed, caspase-3 intensity of the PA-SG group was reduced significantly, but there were no significant differences in intracellular ATP amount and GST activity between the control group and the PA-SG group. Conclusion : The results suggest that Saenggantanggami-bang can be a potential candidate for the clinical treatment of nonalcoholic fatty liver disease.

• Journal of Oriental Neuropsychiatry
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• v.17 no.3
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• pp.21-43
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• 2006

This study was designed to assess Effects of jingansikpungtanggagam-bang on Central Nerve System. Method : jingansikpungtanggagam-bang, a Korean traditional prescription, was evaluated for its anticonvulsant effect, hypnotic activity, analgesic action, anxiolytic effect, memory enhancement, and MAO inhibitory activity and detennined the content of neurotransmitter in brain by HPLC method. Result : 1. The extract increased potently anticonvulsant effect at 1g/kg by 5.6-fold extention of onset time against control group. 2. The extract increased hvrmsis at 500mg/kg by over twofold length of sleeping time compared to control. 3. The extract showed a significant analgesic effect with 86.0% inhibition on writhing frequency at 500mg/kg by phenylquinone-induced writhing test. 4. The extract inhibited dose-dependently the activity of monoamine oxidase in vitro. 5. This prescription increased the brain levels of serotonin and 5-hydroxyindoleacetic acid by 3.3% and 1.4%, respectively. 6. the extract exhibited the anxiolytic effect with 21.3% decrease of the immobility duration against control group. 7. the extract enhanced memory recovery on scopolamine-induced impairment of passive avoidance performance at 1g/kg pretreatment with 20.2% increase of latency time. Conclusion : The result sugguest that jiugansikpungtanggagam-bang can be used effectively as a sedative prescription in Korean traditional medicine.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.38 no.9
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• pp.882-889
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• 2010

Semi-active vibration control is one of the attractive control methods for space application due to its robustness as passive damping system and much higher damping performance than passive system. However, a chattering induced by the sudden variation of damping force at the time of On-Off switching of semi-active control device degrades pointing performance of the on-board payload. In this paper, to enhance the pointing performance of the on-board payload, we proposed a semi-active vibration isolation with a strategy for attenuating chattering effect. Numerical simulation results using simplified analysis model indicated that the proposed semi-active control strategy produced much better isolation performance than the conventional Bang-Bang control semi-active control laws derived from skyhook and LQ theories.

• Proceedings of the KIEE Conference
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• 1987.11a
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• pp.45-48
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• 1987

In applications of step-motor, the requirements of small-size and strong-power gave birth to feed-back drive to the maximum efficiency and complete damping. In this paper, a new scheme that determines switching times from sensed values of position and speed is presented for simple bang-bang type drive circuit. The optimal values of each phase switching times are obtained using conjugate gradient method.

• Journal of Haehwa Medicine
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• v.22 no.2
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• pp.57-66
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• 2014

Objectives : Features of military medicine and war pattern at the time Methods : "Haeng Gun Bang Pyeon Pyeon Bang", military medicine literature, that allows pattern of ancient war to be inferred was considered. First, background of this literature formation was examined, and the contents included were arranged based on table of contents. Lastly, pattern of war at the time and role of military medicine were studied through the meaning of times and medicine in this book. Results : This book was written by Naseyo(羅世瑤, of an unidentifiable period), an intellectual of Qing Period(淸代) in the 2nd year of Emperor Xianfeng(咸豊 2, 1852). It was composed of total 3 volumes and a book, and 684 prescriptions were written under 6 large sections(大門). Conclusions : This book was written in the middle of spirit of the times of national prosperity and military power caused by defeat in the Opium War and popular publication in a series, an academic current of the times. Though there were many treatments about external wound in this book, thoughts of armed forces and combat by people of the time were reflected, including drying method(乾法) making portable foods, drinking control method(戒酒法) to resolve drinking(飮酒) problem in the armed forces, treatment method of infectious disease, information collection method from enemy troops by confession, and various treatments for diseases of military horse. It is expected that this book will be good material for studies in the field of military medicine and used as material for diverse combination studies such as history and military science.

• Korean Journal of Acupuncture
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• v.24 no.4
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• pp.163-180
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• 2007

Objective : Oriental medicines have been applied to Membranous nephropathy(MN) for the purpose on increasing renal blood flow and modulating immune activity in according to Oriental medicine theories. Magsungsinyeom-bang (MSSYB) is one of the prescription which is known to show positive results in clinic with lack of laboratorial evidence. Thus, this study was aimed to evaluate the effects of MSSYB and partially investigate the mechanisms of it. Methods : The effect of MSSYB was evaluated by the morphology for the GBM thickening, protein excretion in urine and biochemical parameters in serum using cBSA-induced MN mice model. Mice were administered with MSSYB(250 or 500 mg/kg) or PBS for control group from experimental week 3 for 4 weeks. Results : 24 hrs proteinuria and the concentrations BUN was significantly decreased in the MS groups compared to the control group while the concentrations of serum albumin was higher in the MS groups than control group. MSSYB didn't affect the ratio of CD3e+/CD or 19CD4+/CD8 in the spleen and kidney, but inhibit the expression of IL-1${\beta}$, TNF-${\alpha}$, IL-6, and production of IgG and IgM. In histological analysis of kidney tissue, thickening of GBM was significantly decreased in the MS group compared to control group. Conclusions : MSSYB showed the positive results on the cBSA-induced membranous nephropathy in mice, thus, it could be a useful candidate for oriental drug for treating the membranous nephropathy in clinic.

• Journal of Bio-Environment Control
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• v.18 no.1
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• pp.60-66
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• 2009

This study was conducted to investigate into the effective drying method for three greens such as bang-a (Isodon japonicus), aster (Aster yomena) and lettuce greens (Ixeris dentata) Nakai. We have dried three greens using the different drying methods, have made methanol extracts and have also determined the physiological activities in $1,000mg{\cdot}L^{-1}$ extracts. Total phenolic compound contents were most increased by 65.1 and $60.2mg{\cdot}L^{-1}$ in the extracts of bang-a and aster which were frozen dried, however, that in lettuce greens were oven dried by $51.2mg{\cdot}L^{-1}$. Total flavonoid contents were extremely much more in bang-a extracts dried in the oven by $70.6mg{\cdot}L^{-1}$, however, aster and lettuce greens extracts frozen dried by 53.9 and $35.8mg{\cdot}L^{-1}$. DPPH radical scavenging activity in bang-a extracts were greatly increased by 78.8% when bang-a were frozen and dried, however, that in aster were not significant by $89.8{\sim}90.9%$. DPPH radical scavenging activities in lettuce greens extracts were became highest in the order f oven drying (91.9%), natural drying (91.0%) and freeze drying methods (90.9%). Nitrite radical scavenging activities in bang-a and aster extracts were most increased in the natural drying treatment by 73.3 and 78.2%, however, that in lettuce greens extracts were highest in freeze drying treatment by 75.1%.

• Journal of KSNVE
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• v.7 no.1
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• pp.161-168
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• 1997

The present paper describes the vibration control experiment of composite plates with bonded piezoelectric sensor and actuator. The system is modeled as two degree-of-freedom system using modal coordinates and the system parameters are obtained from vibration tests. Kalman filter is adopted for extracting modal coordinates from sensor signal, and control algorithms applied to the system are Linear Quadratic Gaussian(LQG) control, Bang-Bang Control (BBC), Negative Velocity Feedback(NVF), Proportional Derivative Control(PDC). From observation of the spillover and control perfomance, it is concluded that a higher order control algorithm such as LQG rather than BBG, NVF, PDC is suitable for efficient simultaneous control of both bending and twisting modes of composite plates.